VRTN (vertebrae development associated)

Gene

• Entrez ID: 55237
• Gene name: Vertebrae development associated
• Gene symbol: VRTN
• Synonyms (NCBI Gene): C14orf115, vertnin
• Chromosome: 14
• Chromosome location: 14q24.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT2367290	hsa-miR-1245	CLIP-seq
MIRT2367291	hsa-miR-150	CLIP-seq
MIRT2367292	hsa-miR-1976	CLIP-seq
MIRT2367293	hsa-miR-3159	CLIP-seq
MIRT2367294	hsa-miR-4312	CLIP-seq
MIRT2367295	hsa-miR-4438	CLIP-seq
MIRT2367296	hsa-miR-4722-3p	CLIP-seq
MIRT2367297	hsa-miR-4757-5p	CLIP-seq
MIRT2367298	hsa-miR-5095	CLIP-seq
MIRT2367299	hsa-miR-518a-3p	CLIP-seq
MIRT2367300	hsa-miR-518b	CLIP-seq
MIRT2367301	hsa-miR-518c	CLIP-seq
MIRT2367302	hsa-miR-518d-3p	CLIP-seq
MIRT2367303	hsa-miR-518e	CLIP-seq
MIRT2367304	hsa-miR-518f	CLIP-seq
MIRT2660783	hsa-miR-2110	CLIP-seq
MIRT2660784	hsa-miR-3150a-3p	CLIP-seq
MIRT2660785	hsa-miR-3189-3p	CLIP-seq
MIRT2660786	hsa-miR-3661	CLIP-seq
MIRT2660787	hsa-miR-4287	CLIP-seq
MIRT2660788	hsa-miR-4450	CLIP-seq
MIRT2660789	hsa-miR-4469	CLIP-seq
MIRT2660790	hsa-miR-4685-3p	CLIP-seq
MIRT2660791	hsa-miR-4713-5p	CLIP-seq
MIRT2660792	hsa-miR-4780	CLIP-seq
MIRT2660793	hsa-miR-623	CLIP-seq
MIRT2660794	hsa-miR-631	CLIP-seq
MIRT2660783	hsa-miR-2110	CLIP-seq
MIRT2660784	hsa-miR-3150a-3p	CLIP-seq
MIRT2660785	hsa-miR-3189-3p	CLIP-seq
MIRT2660786	hsa-miR-3661	CLIP-seq
MIRT2660787	hsa-miR-4287	CLIP-seq
MIRT2660788	hsa-miR-4450	CLIP-seq
MIRT2660789	hsa-miR-4469	CLIP-seq
MIRT2660790	hsa-miR-4685-3p	CLIP-seq
MIRT2660791	hsa-miR-4713-5p	CLIP-seq
MIRT2660792	hsa-miR-4780	CLIP-seq
MIRT2660793	hsa-miR-623	CLIP-seq
MIRT2660794	hsa-miR-631	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	ISS
GO:0043565	Function	Sequence-specific DNA binding	IEA

Other IDs

• MIM: 620468
• HGNC: 20223
• e!Ensembl: ENSG00000133980

Protein

• UniProt ID: Q9H8Y1
• Protein name: Vertnin
• Protein function: Acts as a transcription factor that regulates development of thoracic vertebrae.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01527	HTH_Tnp_1	269 → 322	Transposase	Family

• Sequence:

  MTSRNQLVQKVLQELQEAVECEGLEGLIGASLEAKQVLSSFTLPTCREGGPGLQVLEVDS
  VALSLYPEDAPRNMLPLVCKGEGSLLFEAASMLLWGDAGLSLELRARTVVEMLLHRHYYL
  QGMIDSKVMLQAVRYSLCSEESPEMTSLPPATLEAIFDADVKASCFPSSFSNVWHLYALA
  SVLQRNIYSIYPMRNLKIRPYFNRVIRPRRCDHVPSTLHIMWAGQPLTSHFFRHQYFAPV
  VGLEEVEAEGAPGVAPALPALAPLSSPAKTLELLNREPGLSYSHLCERYSVTKSTFYRWR
  RQSQEHRQKVAARFSAKHFLQDSFHRGGVVPLQQFLQRFPEISRSTYYAWKHELLGSGTC
  PALPPREVLGMEELEKLPEEQVAEEELECSALAVSSPGMVLMQRAKLYLEHCISLNTLVP
  YRCFKRRFPGISRSTYYNWRRKALRRNPSFKPAPALSAAGTPQLASVGEGAVIPWKSEAE
  EGAGNATGEDPPAPGELLPLRMPLSRWQRRLRRAARRQVLSGHLPFCRFRLRYPSLSPSA
  FWVWKSLARGWPRGLSKLQVPVPTLGKGGQEAEEKQEKEAGRDVTAVMAPPVGASSEDVE
  GGPSREGALQEGATAQGQPHSGPLLSQPVVAAAGGRDGRMLVMDMIATTKFKAQAKLFLQ
  KRFQSKSFPSYKEFSALFPLTARSTYYMWKRALYDGLTLVDG

• Sequence length: 702