Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	5523
Gene name Gene Name - the full gene name approved by the HGNC.	Protein phosphatase 2 regulatory subunit B''alpha
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PPP2R3A
Synonyms (NCBI Gene) Gene synonyms aliases	PPP2R3, PR130, PR72
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q22.2-q22.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phos

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019482	hsa-miR-148b-3p	Microarray	17612493
MIRT649473	hsa-miR-4759	HITS-CLIP	23824327
MIRT649472	hsa-miR-3169	HITS-CLIP	23824327
MIRT649471	hsa-miR-8083	HITS-CLIP	23824327
MIRT621045	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621044	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT621043	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT649470	hsa-miR-3117-3p	HITS-CLIP	23824327
MIRT621045	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621044	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT621043	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT649473	hsa-miR-4759	HITS-CLIP	23824327
MIRT649472	hsa-miR-3169	HITS-CLIP	23824327
MIRT649471	hsa-miR-8083	HITS-CLIP	23824327
MIRT621045	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621044	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT621043	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT649470	hsa-miR-3117-3p	HITS-CLIP	23824327
MIRT621045	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621044	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT621043	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT1257635	hsa-miR-1183	CLIP-seq
MIRT1257636	hsa-miR-1202	CLIP-seq
MIRT1257637	hsa-miR-1208	CLIP-seq
MIRT1257638	hsa-miR-1263	CLIP-seq
MIRT1257639	hsa-miR-129-5p	CLIP-seq
MIRT1257640	hsa-miR-1321	CLIP-seq
MIRT1257641	hsa-miR-150	CLIP-seq
MIRT1257642	hsa-miR-181a	CLIP-seq
MIRT1257643	hsa-miR-181b	CLIP-seq
MIRT1257644	hsa-miR-181c	CLIP-seq
MIRT1257645	hsa-miR-181d	CLIP-seq
MIRT1257646	hsa-miR-3152-5p	CLIP-seq
MIRT1257647	hsa-miR-3156-5p	CLIP-seq
MIRT1257648	hsa-miR-3163	CLIP-seq
MIRT1257649	hsa-miR-3189-3p	CLIP-seq
MIRT1257650	hsa-miR-3194-5p	CLIP-seq
MIRT1257651	hsa-miR-3200-3p	CLIP-seq
MIRT1257652	hsa-miR-3202	CLIP-seq
MIRT1257653	hsa-miR-335	CLIP-seq
MIRT1257654	hsa-miR-362-5p	CLIP-seq
MIRT1257655	hsa-miR-3653	CLIP-seq
MIRT1257656	hsa-miR-3658	CLIP-seq
MIRT1257657	hsa-miR-3662	CLIP-seq
MIRT1257658	hsa-miR-3972	CLIP-seq
MIRT1257659	hsa-miR-409-5p	CLIP-seq
MIRT1257660	hsa-miR-410	CLIP-seq
MIRT1257661	hsa-miR-4262	CLIP-seq
MIRT1257662	hsa-miR-4270	CLIP-seq
MIRT1257663	hsa-miR-4280	CLIP-seq
MIRT1257664	hsa-miR-4282	CLIP-seq
MIRT1257665	hsa-miR-4438	CLIP-seq
MIRT1257666	hsa-miR-4441	CLIP-seq
MIRT1257667	hsa-miR-4452	CLIP-seq
MIRT1257668	hsa-miR-4471	CLIP-seq
MIRT1257669	hsa-miR-4533	CLIP-seq
MIRT1257670	hsa-miR-4699-5p	CLIP-seq
MIRT1257671	hsa-miR-4729	CLIP-seq
MIRT1257672	hsa-miR-4732-5p	CLIP-seq
MIRT1257673	hsa-miR-4739	CLIP-seq
MIRT1257674	hsa-miR-4756-5p	CLIP-seq
MIRT1257675	hsa-miR-4764-3p	CLIP-seq
MIRT1257676	hsa-miR-4774-3p	CLIP-seq
MIRT1257677	hsa-miR-500b	CLIP-seq
MIRT1257678	hsa-miR-5095	CLIP-seq
MIRT1257679	hsa-miR-512-3p	CLIP-seq
MIRT1257680	hsa-miR-545	CLIP-seq
MIRT1257681	hsa-miR-577	CLIP-seq
MIRT1257682	hsa-miR-579	CLIP-seq
MIRT1257683	hsa-miR-618	CLIP-seq
MIRT1257684	hsa-miR-628-5p	CLIP-seq
MIRT1257685	hsa-miR-106a	CLIP-seq
MIRT1257686	hsa-miR-106b	CLIP-seq
MIRT1257635	hsa-miR-1183	CLIP-seq
MIRT1257687	hsa-miR-1185	CLIP-seq
MIRT1257688	hsa-miR-1207-5p	CLIP-seq
MIRT1257637	hsa-miR-1208	CLIP-seq
MIRT1257689	hsa-miR-1244	CLIP-seq
MIRT1257690	hsa-miR-1252	CLIP-seq
MIRT1257638	hsa-miR-1263	CLIP-seq
MIRT1257691	hsa-miR-1265	CLIP-seq
MIRT1257692	hsa-miR-1271	CLIP-seq
MIRT1257693	hsa-miR-1273d	CLIP-seq
MIRT1257694	hsa-miR-1273e	CLIP-seq
MIRT1257695	hsa-miR-1275	CLIP-seq
MIRT1257696	hsa-miR-1284	CLIP-seq
MIRT1257697	hsa-miR-1343	CLIP-seq
MIRT1257698	hsa-miR-140-5p	CLIP-seq
MIRT1257699	hsa-miR-17	CLIP-seq
MIRT1257700	hsa-miR-182	CLIP-seq
MIRT1257701	hsa-miR-200b	CLIP-seq
MIRT1257702	hsa-miR-200c	CLIP-seq
MIRT1257703	hsa-miR-20a	CLIP-seq
MIRT1257704	hsa-miR-20b	CLIP-seq
MIRT1257705	hsa-miR-2861	CLIP-seq
MIRT1257706	hsa-miR-3119	CLIP-seq
MIRT1257707	hsa-miR-3134	CLIP-seq
MIRT1257708	hsa-miR-3150b-3p	CLIP-seq
MIRT1257647	hsa-miR-3156-5p	CLIP-seq
MIRT1257709	hsa-miR-3158-3p	CLIP-seq
MIRT1257710	hsa-miR-3192	CLIP-seq
MIRT1257651	hsa-miR-3200-3p	CLIP-seq
MIRT1257711	hsa-miR-3201	CLIP-seq
MIRT1257652	hsa-miR-3202	CLIP-seq
MIRT1257712	hsa-miR-323-3p	CLIP-seq
MIRT1257713	hsa-miR-325	CLIP-seq
MIRT1257714	hsa-miR-338-5p	CLIP-seq
MIRT1257715	hsa-miR-3545-3p	CLIP-seq
MIRT1257716	hsa-miR-3605-5p	CLIP-seq
MIRT1257717	hsa-miR-3609	CLIP-seq
MIRT1257718	hsa-miR-3671	CLIP-seq
MIRT1257719	hsa-miR-3674	CLIP-seq
MIRT1257720	hsa-miR-3679-5p	CLIP-seq
MIRT1257721	hsa-miR-3689a-3p	CLIP-seq
MIRT1257722	hsa-miR-3689c	CLIP-seq
MIRT1257723	hsa-miR-3691-3p	CLIP-seq
MIRT1257724	hsa-miR-382	CLIP-seq
MIRT1257725	hsa-miR-3923	CLIP-seq
MIRT1257726	hsa-miR-3925-3p	CLIP-seq
MIRT1257659	hsa-miR-409-5p	CLIP-seq
MIRT1257727	hsa-miR-429	CLIP-seq
MIRT1257728	hsa-miR-4294	CLIP-seq
MIRT1257729	hsa-miR-4303	CLIP-seq
MIRT1257730	hsa-miR-4423-5p	CLIP-seq
MIRT1257731	hsa-miR-4434	CLIP-seq
MIRT1257732	hsa-miR-4464	CLIP-seq
MIRT1257733	hsa-miR-4476	CLIP-seq
MIRT1257734	hsa-miR-4477a	CLIP-seq
MIRT1257735	hsa-miR-4493	CLIP-seq
MIRT1257736	hsa-miR-4495	CLIP-seq
MIRT1257737	hsa-miR-4516	CLIP-seq
MIRT1257669	hsa-miR-4533	CLIP-seq
MIRT1257738	hsa-miR-4649-3p	CLIP-seq
MIRT1257739	hsa-miR-4665-5p	CLIP-seq
MIRT1257740	hsa-miR-4680-5p	CLIP-seq
MIRT1257741	hsa-miR-4689	CLIP-seq
MIRT1257742	hsa-miR-4712-5p	CLIP-seq
MIRT1257743	hsa-miR-4728-5p	CLIP-seq
MIRT1257672	hsa-miR-4732-5p	CLIP-seq
MIRT1257744	hsa-miR-4736	CLIP-seq
MIRT1257745	hsa-miR-4748	CLIP-seq
MIRT1257746	hsa-miR-4763-3p	CLIP-seq
MIRT1257675	hsa-miR-4764-3p	CLIP-seq
MIRT1257747	hsa-miR-4781-3p	CLIP-seq
MIRT1257748	hsa-miR-4784	CLIP-seq
MIRT1257749	hsa-miR-4791	CLIP-seq
MIRT1257750	hsa-miR-4796-3p	CLIP-seq
MIRT1257751	hsa-miR-499-3p	CLIP-seq
MIRT1257752	hsa-miR-499a-3p	CLIP-seq
MIRT1257753	hsa-miR-508-5p	CLIP-seq
MIRT1257754	hsa-miR-519d	CLIP-seq
MIRT1257755	hsa-miR-544b	CLIP-seq
MIRT1257680	hsa-miR-545	CLIP-seq
MIRT1257756	hsa-miR-548ah	CLIP-seq
MIRT1257683	hsa-miR-618	CLIP-seq
MIRT1257757	hsa-miR-661	CLIP-seq
MIRT1257758	hsa-miR-770-5p	CLIP-seq
MIRT1257759	hsa-miR-93	CLIP-seq
MIRT1257760	hsa-miR-96	CLIP-seq
MIRT2075902	hsa-miR-103b	CLIP-seq
MIRT1257685	hsa-miR-106a	CLIP-seq
MIRT1257686	hsa-miR-106b	CLIP-seq
MIRT2075903	hsa-miR-1184	CLIP-seq
MIRT1257636	hsa-miR-1202	CLIP-seq
MIRT1257694	hsa-miR-1273e	CLIP-seq
MIRT1257695	hsa-miR-1275	CLIP-seq
MIRT2075904	hsa-miR-1304	CLIP-seq
MIRT1257699	hsa-miR-17	CLIP-seq
MIRT1257703	hsa-miR-20a	CLIP-seq
MIRT1257704	hsa-miR-20b	CLIP-seq
MIRT2075905	hsa-miR-3123	CLIP-seq
MIRT1257707	hsa-miR-3134	CLIP-seq
MIRT2075906	hsa-miR-3135	CLIP-seq
MIRT1257647	hsa-miR-3156-5p	CLIP-seq
MIRT1257650	hsa-miR-3194-5p	CLIP-seq
MIRT1257652	hsa-miR-3202	CLIP-seq
MIRT2075907	hsa-miR-3622a-3p	CLIP-seq
MIRT2075908	hsa-miR-3622b-3p	CLIP-seq
MIRT2075909	hsa-miR-3652	CLIP-seq
MIRT1257718	hsa-miR-3671	CLIP-seq
MIRT1257724	hsa-miR-382	CLIP-seq
MIRT2075910	hsa-miR-3925-5p	CLIP-seq
MIRT2075911	hsa-miR-3929	CLIP-seq
MIRT1257658	hsa-miR-3972	CLIP-seq
MIRT2075912	hsa-miR-4418	CLIP-seq
MIRT2075913	hsa-miR-4419b	CLIP-seq
MIRT2075914	hsa-miR-4430	CLIP-seq
MIRT1257731	hsa-miR-4434	CLIP-seq
MIRT2075915	hsa-miR-4478	CLIP-seq
MIRT1257737	hsa-miR-4516	CLIP-seq
MIRT1257669	hsa-miR-4533	CLIP-seq
MIRT1257739	hsa-miR-4665-5p	CLIP-seq
MIRT2075916	hsa-miR-4704-3p	CLIP-seq
MIRT1257672	hsa-miR-4732-5p	CLIP-seq
MIRT2075917	hsa-miR-4796-5p	CLIP-seq
MIRT1257751	hsa-miR-499-3p	CLIP-seq
MIRT1257752	hsa-miR-499a-3p	CLIP-seq
MIRT2075918	hsa-miR-509-3-5p	CLIP-seq
MIRT2075919	hsa-miR-509-5p	CLIP-seq
MIRT2075920	hsa-miR-514	CLIP-seq
MIRT2075921	hsa-miR-514b-3p	CLIP-seq
MIRT1257754	hsa-miR-519d	CLIP-seq
MIRT2075922	hsa-miR-520g	CLIP-seq
MIRT2075923	hsa-miR-520h	CLIP-seq
MIRT2075924	hsa-miR-589	CLIP-seq
MIRT2075925	hsa-miR-645	CLIP-seq
MIRT2075926	hsa-miR-891b	CLIP-seq
MIRT1257759	hsa-miR-93	CLIP-seq
MIRT1257685	hsa-miR-106a	CLIP-seq
MIRT1257686	hsa-miR-106b	CLIP-seq
MIRT1257687	hsa-miR-1185	CLIP-seq
MIRT1257636	hsa-miR-1202	CLIP-seq
MIRT1257689	hsa-miR-1244	CLIP-seq
MIRT1257691	hsa-miR-1265	CLIP-seq
MIRT2302548	hsa-miR-1305	CLIP-seq
MIRT1257698	hsa-miR-140-5p	CLIP-seq
MIRT1257699	hsa-miR-17	CLIP-seq
MIRT1257703	hsa-miR-20a	CLIP-seq
MIRT1257704	hsa-miR-20b	CLIP-seq
MIRT1257647	hsa-miR-3156-5p	CLIP-seq
MIRT1257650	hsa-miR-3194-5p	CLIP-seq
MIRT1257652	hsa-miR-3202	CLIP-seq
MIRT1257713	hsa-miR-325	CLIP-seq
MIRT1257714	hsa-miR-338-5p	CLIP-seq
MIRT1257716	hsa-miR-3605-5p	CLIP-seq
MIRT1257717	hsa-miR-3609	CLIP-seq
MIRT2075909	hsa-miR-3652	CLIP-seq
MIRT1257718	hsa-miR-3671	CLIP-seq
MIRT1257720	hsa-miR-3679-5p	CLIP-seq
MIRT2302549	hsa-miR-384	CLIP-seq
MIRT1257725	hsa-miR-3923	CLIP-seq
MIRT1257658	hsa-miR-3972	CLIP-seq
MIRT1257659	hsa-miR-409-5p	CLIP-seq
MIRT2075914	hsa-miR-4430	CLIP-seq
MIRT1257735	hsa-miR-4493	CLIP-seq
MIRT1257736	hsa-miR-4495	CLIP-seq
MIRT1257669	hsa-miR-4533	CLIP-seq
MIRT1257750	hsa-miR-4796-3p	CLIP-seq
MIRT2302550	hsa-miR-498	CLIP-seq
MIRT2302551	hsa-miR-513a-3p	CLIP-seq
MIRT1257754	hsa-miR-519d	CLIP-seq
MIRT1257755	hsa-miR-544b	CLIP-seq
MIRT1257680	hsa-miR-545	CLIP-seq
MIRT1257756	hsa-miR-548ah	CLIP-seq
MIRT2302552	hsa-miR-576-3p	CLIP-seq
MIRT2302553	hsa-miR-767-5p	CLIP-seq
MIRT1257759	hsa-miR-93	CLIP-seq
MIRT1257685	hsa-miR-106a	CLIP-seq
MIRT1257686	hsa-miR-106b	CLIP-seq
MIRT1257636	hsa-miR-1202	CLIP-seq
MIRT1257699	hsa-miR-17	CLIP-seq
MIRT1257703	hsa-miR-20a	CLIP-seq
MIRT1257704	hsa-miR-20b	CLIP-seq
MIRT1257658	hsa-miR-3972	CLIP-seq
MIRT1257659	hsa-miR-409-5p	CLIP-seq
MIRT1257754	hsa-miR-519d	CLIP-seq
MIRT1257759	hsa-miR-93	CLIP-seq
MIRT1257694	hsa-miR-1273e	CLIP-seq
MIRT1257695	hsa-miR-1275	CLIP-seq
MIRT2457065	hsa-miR-128	CLIP-seq
MIRT2457066	hsa-miR-1909	CLIP-seq
MIRT2457067	hsa-miR-193a-5p	CLIP-seq
MIRT1257707	hsa-miR-3134	CLIP-seq
MIRT2075906	hsa-miR-3135	CLIP-seq
MIRT2457068	hsa-miR-3194-3p	CLIP-seq
MIRT1257711	hsa-miR-3201	CLIP-seq
MIRT1257724	hsa-miR-382	CLIP-seq
MIRT2457069	hsa-miR-431	CLIP-seq
MIRT1257734	hsa-miR-4477a	CLIP-seq
MIRT2457070	hsa-miR-4504	CLIP-seq
MIRT1257739	hsa-miR-4665-5p	CLIP-seq
MIRT2457071	hsa-miR-4672	CLIP-seq
MIRT1257749	hsa-miR-4791	CLIP-seq
MIRT2457072	hsa-miR-615-5p	CLIP-seq
MIRT2075917	hsa-miR-4796-5p	CLIP-seq
MIRT1257751	hsa-miR-499-3p	CLIP-seq
MIRT1257752	hsa-miR-499a-3p	CLIP-seq
MIRT1257694	hsa-miR-1273e	CLIP-seq
MIRT1257695	hsa-miR-1275	CLIP-seq
MIRT1257707	hsa-miR-3134	CLIP-seq
MIRT1257711	hsa-miR-3201	CLIP-seq
MIRT1257654	hsa-miR-362-5p	CLIP-seq
MIRT1257724	hsa-miR-382	CLIP-seq
MIRT1257734	hsa-miR-4477a	CLIP-seq
MIRT1257739	hsa-miR-4665-5p	CLIP-seq
MIRT1257749	hsa-miR-4791	CLIP-seq
MIRT2075917	hsa-miR-4796-5p	CLIP-seq
MIRT1257751	hsa-miR-499-3p	CLIP-seq
MIRT1257752	hsa-miR-499a-3p	CLIP-seq
MIRT1257677	hsa-miR-500b	CLIP-seq
MIRT2599191	hsa-miR-501-5p	CLIP-seq
MIRT2302552	hsa-miR-576-3p	CLIP-seq
MIRT2599192	hsa-miR-633	CLIP-seq
MIRT2302553	hsa-miR-767-5p	CLIP-seq

Show/Hide all(22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000159	Component	Protein phosphatase type 2A complex	IBA
GO:0000159	Component	Protein phosphatase type 2A complex	IDA	15687260, 17055435
GO:0000159	Component	Protein phosphatase type 2A complex	ISS	1849734
GO:0001754	Process	Eye photoreceptor cell differentiation	IGI	15687260
GO:0001756	Process	Somitogenesis	IBA
GO:0001756	Process	Somitogenesis	IGI	15687260
GO:0005509	Function	Calcium ion binding	IEA
GO:0005515	Function	Protein binding	IPI	9847399, 15687260, 16567647, 30595372
GO:0006470	Process	Protein dephosphorylation	ISS	1849734
GO:0007525	Process	Somatic muscle development	IBA
GO:0007525	Process	Somatic muscle development	IGI	15687260
GO:0019888	Function	Protein phosphatase regulator activity	IBA
GO:0019888	Function	Protein phosphatase regulator activity	TAS	8392071
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	15687260
GO:0045732	Process	Positive regulation of protein catabolic process	IMP	15687260
GO:0046872	Function	Metal ion binding	IEA
GO:0060828	Process	Regulation of canonical Wnt signaling pathway	IBA
GO:0061053	Process	Somite development	ISS	16567647
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	IGI	15687260
GO:0090249	Process	Regulation of cell migration involved in somitogenic axis elongation	IBA
GO:0090249	Process	Regulation of cell migration involved in somitogenic axis elongation	IGI	15687260
GO:0090263	Process	Positive regulation of canonical Wnt signaling pathway	IDA	16567647

MIM	HGNC	e!Ensembl
604944	9307	ENSG00000073711

Protein

UniProt ID

Q06190

Protein name

Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha (PP2A subunit B isoform PR72/PR130) (PP2A subunit B isoform R3 isoform) (PP2A subunit B isoforms B''-PR72/PR130) (PP2A subunit B isoforms B72/B130) (Serine/threonine-protein phos

Protein function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment.

PDB

4I5J , 4I5K

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF17958	EF-hand_13	796 → 885	EF-hand domain	Domain
PF13499	EF-hand_7	900 → 1002	EF-hand domain pair	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in heart, brain, placenta, lung, muscle and kidney.

Sequence

MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPV
SQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFA
SGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSS
SVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCS
EDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSG
NNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNS
RKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEE
SDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNL
PKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFL
NSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIED
FAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT
PEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPD
TCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTA
QSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPE
FHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHF
YVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYAD
FVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHD
LLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDG
PEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEK
CGKLQSVDEE

Sequence length

1150

Interactions

View interactions

	KEGG
	mRNA surveillance pathway Sphingolipid signaling pathway PI3K-Akt signaling pathway AMPK signaling pathway Adrenergic signaling in cardiomyocytes T cell receptor signaling pathway Dopaminergic synapse Human papillomavirus infection

Show/Hide Unknown Diseases (8)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Atrial Fibrillation	Atrial fibrillation	N/A	N/A	GWAS
Coronary artery disease	Coronary artery disease	N/A	N/A	GWAS
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Dyslexia	Dyslexia	N/A	N/A	GWAS
Heart Failure	Heart failure	N/A	N/A	GWAS
Myocardial Infarction	Myocardial infarction	N/A	N/A	GWAS
Neuroticism	Neuroticism	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (11)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Ataxia Telangiectasia	Associate	19430199
Carcinoma Hepatocellular	Associate	35945177
Fibrosarcoma	Associate	26945059
Hepatitis B	Associate	19430199
Leukemia	Associate	19430199
Lipoma	Associate	26945059
Lymphoma Non Hodgkin	Associate	36788429
Neoplasms	Associate	19430199, 35945177
Pancreatic Neoplasms	Associate	35077391
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	19430199
Supranuclear Palsy Progressive	Associate	33635380

PPP2R3A (protein phosphatase 2 regulatory subunit B''alpha)