Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	55227
Gene name Gene Name - the full gene name approved by the HGNC.	Leucine rich repeat containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LRRC1
Synonyms (NCBI Gene) Gene synonyms aliases	LANO, dJ523E19.1
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p12.1

Show/Hide all(248)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002712	hsa-miR-124-3p	Microarray	15685193
MIRT002712	hsa-miR-124-3p	Microarray	18668037
MIRT002712	hsa-miR-124-3p	Microarray	15685193
MIRT030660	hsa-miR-22-3p	Sequencing	20371350
MIRT002712	hsa-miR-124-3p	PAR-CLIP	20371350
MIRT002712	hsa-miR-124-3p	PAR-CLIP	20371350
MIRT361115	hsa-miR-506-3p	PAR-CLIP	20371350
MIRT566868	hsa-miR-3714	PAR-CLIP	20371350
MIRT566869	hsa-miR-3910	PAR-CLIP	20371350
MIRT566865	hsa-miR-101-3p	PAR-CLIP	20371350
MIRT566867	hsa-miR-144-3p	PAR-CLIP	20371350
MIRT361120	hsa-miR-5582-5p	PAR-CLIP	20371350
MIRT361117	hsa-miR-3681-5p	PAR-CLIP	20371350
MIRT361121	hsa-miR-6849-5p	PAR-CLIP	20371350
MIRT566866	hsa-miR-5579-5p	PAR-CLIP	20371350
MIRT361113	hsa-miR-125b-2-3p	PAR-CLIP	20371350
MIRT361116	hsa-miR-1193	PAR-CLIP	20371350
MIRT361118	hsa-miR-3691-5p	PAR-CLIP	20371350
MIRT566865	hsa-miR-101-3p	PAR-CLIP	20371350
MIRT361114	hsa-miR-432-3p	PAR-CLIP	20371350
MIRT566864	hsa-miR-150-3p	PAR-CLIP	20371350
MIRT445853	hsa-miR-4282	PAR-CLIP	22100165
MIRT445851	hsa-miR-4635	PAR-CLIP	22100165
MIRT445852	hsa-miR-7843-3p	PAR-CLIP	22100165
MIRT445850	hsa-miR-127-5p	PAR-CLIP	22100165
MIRT440312	hsa-miR-432-5p	HITS-CLIP	24374217
MIRT440310	hsa-miR-1185-2-3p	HITS-CLIP	24374217
MIRT440311	hsa-miR-1185-1-3p	HITS-CLIP	24374217
MIRT440312	hsa-miR-432-5p	HITS-CLIP	24374217
MIRT440310	hsa-miR-1185-2-3p	HITS-CLIP	24374217
MIRT440311	hsa-miR-1185-1-3p	HITS-CLIP	24374217
MIRT733765	hsa-miR-193a-3p	Luciferase reporter assay, Western blotting, qRT-PCR, Flow cytometry	32978367
MIRT002712	hsa-miR-124-3p	PAR-CLIP	20371350
MIRT002712	hsa-miR-124-3p	PAR-CLIP	20371350
MIRT361115	hsa-miR-506-3p	PAR-CLIP	20371350
MIRT566868	hsa-miR-3714	PAR-CLIP	20371350
MIRT566869	hsa-miR-3910	PAR-CLIP	20371350
MIRT566865	hsa-miR-101-3p	PAR-CLIP	20371350
MIRT566867	hsa-miR-144-3p	PAR-CLIP	20371350
MIRT361120	hsa-miR-5582-5p	PAR-CLIP	20371350
MIRT361117	hsa-miR-3681-5p	PAR-CLIP	20371350
MIRT361121	hsa-miR-6849-5p	PAR-CLIP	20371350
MIRT566866	hsa-miR-5579-5p	PAR-CLIP	20371350
MIRT361113	hsa-miR-125b-2-3p	PAR-CLIP	20371350
MIRT361116	hsa-miR-1193	PAR-CLIP	20371350
MIRT361118	hsa-miR-3691-5p	PAR-CLIP	20371350
MIRT566865	hsa-miR-101-3p	PAR-CLIP	20371350
MIRT361114	hsa-miR-432-3p	PAR-CLIP	20371350
MIRT566864	hsa-miR-150-3p	PAR-CLIP	20371350
MIRT445853	hsa-miR-4282	PAR-CLIP	22100165
MIRT445851	hsa-miR-4635	PAR-CLIP	22100165
MIRT445852	hsa-miR-7843-3p	PAR-CLIP	22100165
MIRT445850	hsa-miR-127-5p	PAR-CLIP	22100165
MIRT1118772	hsa-miR-1208	CLIP-seq
MIRT1118773	hsa-miR-124	CLIP-seq
MIRT1118774	hsa-miR-1255a	CLIP-seq
MIRT1118775	hsa-miR-1255b	CLIP-seq
MIRT1118776	hsa-miR-128	CLIP-seq
MIRT1118777	hsa-miR-1323	CLIP-seq
MIRT1118778	hsa-miR-1324	CLIP-seq
MIRT1118779	hsa-miR-134	CLIP-seq
MIRT1118780	hsa-miR-1343	CLIP-seq
MIRT1118781	hsa-miR-141	CLIP-seq
MIRT1118782	hsa-miR-200a	CLIP-seq
MIRT1118783	hsa-miR-22	CLIP-seq
MIRT1118784	hsa-miR-2467-3p	CLIP-seq
MIRT1118785	hsa-miR-2467-5p	CLIP-seq
MIRT1118786	hsa-miR-3118	CLIP-seq
MIRT1118787	hsa-miR-3125	CLIP-seq
MIRT1118788	hsa-miR-3160-3p	CLIP-seq
MIRT1118789	hsa-miR-3161	CLIP-seq
MIRT1118790	hsa-miR-3166	CLIP-seq
MIRT1118791	hsa-miR-3188	CLIP-seq
MIRT1118792	hsa-miR-3192	CLIP-seq
MIRT1118793	hsa-miR-3200-5p	CLIP-seq
MIRT1118794	hsa-miR-329	CLIP-seq
MIRT1118795	hsa-miR-3591-3p	CLIP-seq
MIRT1118796	hsa-miR-3613-3p	CLIP-seq
MIRT1118797	hsa-miR-362-3p	CLIP-seq
MIRT1118798	hsa-miR-3662	CLIP-seq
MIRT1118799	hsa-miR-3685	CLIP-seq
MIRT1118800	hsa-miR-3689d	CLIP-seq
MIRT1118801	hsa-miR-384	CLIP-seq
MIRT1118802	hsa-miR-3916	CLIP-seq
MIRT1118803	hsa-miR-3920	CLIP-seq
MIRT1118804	hsa-miR-3927	CLIP-seq
MIRT1118805	hsa-miR-3975	CLIP-seq
MIRT1118806	hsa-miR-421	CLIP-seq
MIRT1118807	hsa-miR-4303	CLIP-seq
MIRT1118808	hsa-miR-4305	CLIP-seq
MIRT1118809	hsa-miR-4316	CLIP-seq
MIRT1118810	hsa-miR-432	CLIP-seq
MIRT1118811	hsa-miR-4443	CLIP-seq
MIRT1118812	hsa-miR-4487	CLIP-seq
MIRT1118813	hsa-miR-4532	CLIP-seq
MIRT1118814	hsa-miR-4699-3p	CLIP-seq
MIRT1118815	hsa-miR-4709-5p	CLIP-seq
MIRT1118816	hsa-miR-4733-3p	CLIP-seq
MIRT1118817	hsa-miR-4738-3p	CLIP-seq
MIRT1118818	hsa-miR-4760-3p	CLIP-seq
MIRT1118819	hsa-miR-485-5p	CLIP-seq
MIRT1118820	hsa-miR-506	CLIP-seq
MIRT1118821	hsa-miR-548a-3p	CLIP-seq
MIRT1118822	hsa-miR-548ac	CLIP-seq
MIRT1118823	hsa-miR-548ae	CLIP-seq
MIRT1118824	hsa-miR-548aj	CLIP-seq
MIRT1118825	hsa-miR-548am	CLIP-seq
MIRT1118826	hsa-miR-548d-3p	CLIP-seq
MIRT1118827	hsa-miR-548e	CLIP-seq
MIRT1118828	hsa-miR-548f	CLIP-seq
MIRT1118829	hsa-miR-548o	CLIP-seq
MIRT1118830	hsa-miR-548x	CLIP-seq
MIRT1118831	hsa-miR-548z	CLIP-seq
MIRT1118832	hsa-miR-558	CLIP-seq
MIRT1118833	hsa-miR-579	CLIP-seq
MIRT1118834	hsa-miR-590-3p	CLIP-seq
MIRT1118835	hsa-miR-618	CLIP-seq
MIRT1118836	hsa-miR-646	CLIP-seq
MIRT1118837	hsa-miR-659	CLIP-seq
MIRT1118838	hsa-miR-7	CLIP-seq
MIRT1118839	hsa-miR-873	CLIP-seq
MIRT1118840	hsa-miR-890	CLIP-seq
MIRT1118841	hsa-miR-922	CLIP-seq
MIRT1118776	hsa-miR-128	CLIP-seq
MIRT1118779	hsa-miR-134	CLIP-seq
MIRT1118786	hsa-miR-3118	CLIP-seq
MIRT1118776	hsa-miR-128	CLIP-seq
MIRT1118779	hsa-miR-134	CLIP-seq
MIRT1118786	hsa-miR-3118	CLIP-seq
MIRT1118773	hsa-miR-124	CLIP-seq
MIRT1118774	hsa-miR-1255a	CLIP-seq
MIRT1118775	hsa-miR-1255b	CLIP-seq
MIRT1118780	hsa-miR-1343	CLIP-seq
MIRT1118784	hsa-miR-2467-3p	CLIP-seq
MIRT2033581	hsa-miR-3117-5p	CLIP-seq
MIRT1118787	hsa-miR-3125	CLIP-seq
MIRT1118792	hsa-miR-3192	CLIP-seq
MIRT2033582	hsa-miR-3622a-5p	CLIP-seq
MIRT2033583	hsa-miR-3660	CLIP-seq
MIRT1118802	hsa-miR-3916	CLIP-seq
MIRT1118810	hsa-miR-432	CLIP-seq
MIRT2033584	hsa-miR-4423-3p	CLIP-seq
MIRT1118811	hsa-miR-4443	CLIP-seq
MIRT2033585	hsa-miR-4459	CLIP-seq
MIRT2033586	hsa-miR-4526	CLIP-seq
MIRT2033587	hsa-miR-4528	CLIP-seq
MIRT2033588	hsa-miR-4712-3p	CLIP-seq
MIRT2033589	hsa-miR-4753-3p	CLIP-seq
MIRT2033590	hsa-miR-4768-5p	CLIP-seq
MIRT2033591	hsa-miR-4793-3p	CLIP-seq
MIRT1118820	hsa-miR-506	CLIP-seq
MIRT2033592	hsa-miR-520d-5p	CLIP-seq
MIRT2033593	hsa-miR-524-5p	CLIP-seq
MIRT1118821	hsa-miR-548a-3p	CLIP-seq
MIRT1118827	hsa-miR-548e	CLIP-seq
MIRT1118828	hsa-miR-548f	CLIP-seq
MIRT2033594	hsa-miR-556-3p	CLIP-seq
MIRT1118833	hsa-miR-579	CLIP-seq
MIRT2033595	hsa-miR-622	CLIP-seq
MIRT2033596	hsa-miR-630	CLIP-seq
MIRT1118836	hsa-miR-646	CLIP-seq
MIRT1118838	hsa-miR-7	CLIP-seq
MIRT2033597	hsa-miR-759	CLIP-seq
MIRT1118839	hsa-miR-873	CLIP-seq
MIRT1118840	hsa-miR-890	CLIP-seq
MIRT1118841	hsa-miR-922	CLIP-seq
MIRT2264024	hsa-miR-101	CLIP-seq
MIRT1118773	hsa-miR-124	CLIP-seq
MIRT2264025	hsa-miR-1275	CLIP-seq
MIRT1118776	hsa-miR-128	CLIP-seq
MIRT1118778	hsa-miR-1324	CLIP-seq
MIRT1118779	hsa-miR-134	CLIP-seq
MIRT1118781	hsa-miR-141	CLIP-seq
MIRT2264026	hsa-miR-144	CLIP-seq
MIRT2264027	hsa-miR-199a-3p	CLIP-seq
MIRT2264028	hsa-miR-199b-3p	CLIP-seq
MIRT1118782	hsa-miR-200a	CLIP-seq
MIRT1118784	hsa-miR-2467-3p	CLIP-seq
MIRT2033581	hsa-miR-3117-5p	CLIP-seq
MIRT1118786	hsa-miR-3118	CLIP-seq
MIRT1118787	hsa-miR-3125	CLIP-seq
MIRT2264029	hsa-miR-3129-5p	CLIP-seq
MIRT1118798	hsa-miR-3662	CLIP-seq
MIRT2264030	hsa-miR-3675-3p	CLIP-seq
MIRT2264031	hsa-miR-3681	CLIP-seq
MIRT1118799	hsa-miR-3685	CLIP-seq
MIRT1118800	hsa-miR-3689d	CLIP-seq
MIRT1118801	hsa-miR-384	CLIP-seq
MIRT1118802	hsa-miR-3916	CLIP-seq
MIRT1118803	hsa-miR-3920	CLIP-seq
MIRT1118804	hsa-miR-3927	CLIP-seq
MIRT1118808	hsa-miR-4305	CLIP-seq
MIRT1118810	hsa-miR-432	CLIP-seq
MIRT1118811	hsa-miR-4443	CLIP-seq
MIRT2264032	hsa-miR-4450	CLIP-seq
MIRT2033585	hsa-miR-4459	CLIP-seq
MIRT2264033	hsa-miR-4471	CLIP-seq
MIRT2264034	hsa-miR-4525	CLIP-seq
MIRT2033587	hsa-miR-4528	CLIP-seq
MIRT2264035	hsa-miR-4665-5p	CLIP-seq
MIRT2264036	hsa-miR-4698	CLIP-seq
MIRT2033588	hsa-miR-4712-3p	CLIP-seq
MIRT2264037	hsa-miR-4723-5p	CLIP-seq
MIRT1118817	hsa-miR-4738-3p	CLIP-seq
MIRT2033589	hsa-miR-4753-3p	CLIP-seq
MIRT2033590	hsa-miR-4768-5p	CLIP-seq
MIRT2033591	hsa-miR-4793-3p	CLIP-seq
MIRT1118820	hsa-miR-506	CLIP-seq
MIRT2033592	hsa-miR-520d-5p	CLIP-seq
MIRT2033593	hsa-miR-524-5p	CLIP-seq
MIRT1118821	hsa-miR-548a-3p	CLIP-seq
MIRT1118827	hsa-miR-548e	CLIP-seq
MIRT1118828	hsa-miR-548f	CLIP-seq
MIRT1118833	hsa-miR-579	CLIP-seq
MIRT2264038	hsa-miR-625	CLIP-seq
MIRT2264039	hsa-miR-642b	CLIP-seq
MIRT2264040	hsa-miR-652	CLIP-seq
MIRT1118838	hsa-miR-7	CLIP-seq
MIRT1118839	hsa-miR-873	CLIP-seq
MIRT1118840	hsa-miR-890	CLIP-seq
MIRT1118841	hsa-miR-922	CLIP-seq
MIRT2264041	hsa-miR-936	CLIP-seq
MIRT2033587	hsa-miR-4528	CLIP-seq
MIRT2033588	hsa-miR-4712-3p	CLIP-seq
MIRT2033591	hsa-miR-4793-3p	CLIP-seq
MIRT2264024	hsa-miR-101	CLIP-seq
MIRT1118773	hsa-miR-124	CLIP-seq
MIRT2264026	hsa-miR-144	CLIP-seq
MIRT2563169	hsa-miR-3117-3p	CLIP-seq
MIRT2033581	hsa-miR-3117-5p	CLIP-seq
MIRT2563170	hsa-miR-3163	CLIP-seq
MIRT2563171	hsa-miR-3169	CLIP-seq
MIRT2264031	hsa-miR-3681	CLIP-seq
MIRT2033587	hsa-miR-4528	CLIP-seq
MIRT2033588	hsa-miR-4712-3p	CLIP-seq
MIRT2563172	hsa-miR-4759	CLIP-seq
MIRT2033591	hsa-miR-4793-3p	CLIP-seq
MIRT1118820	hsa-miR-506	CLIP-seq
MIRT1118822	hsa-miR-548ac	CLIP-seq
MIRT1118823	hsa-miR-548ae	CLIP-seq
MIRT1118824	hsa-miR-548aj	CLIP-seq
MIRT1118825	hsa-miR-548am	CLIP-seq
MIRT1118826	hsa-miR-548d-3p	CLIP-seq
MIRT2563173	hsa-miR-548t	CLIP-seq
MIRT1118830	hsa-miR-548x	CLIP-seq
MIRT1118831	hsa-miR-548z	CLIP-seq
MIRT2264039	hsa-miR-642b	CLIP-seq
MIRT2563174	hsa-miR-651	CLIP-seq

Show/Hide all(2)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005829	Component	Cytosol	IDA
GO:0016020	Component	Membrane	IEA

MIM	HGNC	e!Ensembl
608195	14307	ENSG00000137269

Protein

UniProt ID

Q9BTT6

Protein name

Leucine-rich repeat-containing protein 1 (LANO adapter protein) (LAP and no PDZ protein)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13855	LRR_8	36 → 94	Leucine rich repeat	Repeat
PF13855	LRR_8	198 → 255	Leucine rich repeat	Repeat
PF13855	LRR_8	266 → 324	Leucine rich repeat	Repeat

Tissue specificity

TISSUE SPECIFICITY: Expressed strongly in testis and placenta, followed by heart, lung, kidney, thyroid, trachea, colon, prostate and pancreas. {ECO:0000269|PubMed:11440998}.

Sequence

MFHCIPLWRCNRHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVK
LRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRL
PESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELD
LGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEIS
GLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQ
LLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATEL
HVLDVAGNRLLHLPLSLTALKLKALWLSDNQSQPLLTFQTDTDYTTGEKILTCVLLPQLP
SEPTCQENLPRCGALENLVNDVSDEAWNERAVNRVSAIRFVEDEKDEEDNETRTLLRRAT
PHPGELKHMKKTVENLRNDMNAAKGLDSNKNEVNHAIDRVTTSV

Sequence length

524

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Metabolic Syndrome	Metabolic Syndrome	GWAS
Diabetes	Diabetes	GWAS

Show/Hide Text Mining Associations (9)

Disease Name	Relationship Type	References
Associations from Text Mining
Carcinoma Hepatocellular	Associate	32213663, 37505155
Carcinoma Non Small Cell Lung	Associate	32978367
Cholangiocarcinoma	Associate	34898474
Cognition Disorders	Associate	32938779
Embolic Stroke	Associate	32172663
Neoplasm Metastasis	Associate	32213663
Neoplasms	Associate	36370237, 37505155
Sarcoma	Associate	34294833
Stroke	Associate	32172663

LRRC1 (leucine rich repeat containing 1)