Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	5522
Gene name	Protein phosphatase 2 regulatory subunit Bgamma
Gene symbol	PPP2R2C
Synonyms (NCBI Gene)	B55-GAMMAB55gammaIMYPNOIMYPNO1PR52PR55G
Chromosome	4
Chromosome location	4p16.1
Summary	The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heter

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miRTarBase ID	miRNA	Experiments	Reference
MIRT021554	hsa-miR-142-3p	Microarray	17612493
MIRT1257566	hsa-miR-1284	CLIP-seq
MIRT1257567	hsa-miR-300	CLIP-seq
MIRT1257568	hsa-miR-3591-3p	CLIP-seq
MIRT1257569	hsa-miR-3613-3p	CLIP-seq
MIRT1257570	hsa-miR-3688-3p	CLIP-seq
MIRT1257571	hsa-miR-3691-3p	CLIP-seq
MIRT1257572	hsa-miR-381	CLIP-seq
MIRT1257573	hsa-miR-4261	CLIP-seq
MIRT1257574	hsa-miR-4506	CLIP-seq
MIRT1257575	hsa-miR-4666-3p	CLIP-seq
MIRT1257576	hsa-miR-548aa	CLIP-seq
MIRT1257577	hsa-miR-548p	CLIP-seq
MIRT1257578	hsa-miR-555	CLIP-seq
MIRT1257579	hsa-miR-561	CLIP-seq
MIRT1257580	hsa-miR-607	CLIP-seq
MIRT1257581	hsa-miR-942	CLIP-seq
MIRT1257582	hsa-miR-1207-5p	CLIP-seq
MIRT1257583	hsa-miR-1253	CLIP-seq
MIRT1257584	hsa-miR-24	CLIP-seq
MIRT1257585	hsa-miR-2467-3p	CLIP-seq
MIRT1257586	hsa-miR-2467-5p	CLIP-seq
MIRT1257587	hsa-miR-3665	CLIP-seq
MIRT1257588	hsa-miR-3919	CLIP-seq
MIRT1257589	hsa-miR-4736	CLIP-seq
MIRT1257590	hsa-miR-4756-3p	CLIP-seq
MIRT1257591	hsa-miR-4763-3p	CLIP-seq
MIRT1257592	hsa-miR-545	CLIP-seq
MIRT1257593	hsa-miR-610	CLIP-seq
MIRT1257594	hsa-miR-922	CLIP-seq
MIRT1257595	hsa-miR-1243	CLIP-seq
MIRT1257596	hsa-miR-1273f	CLIP-seq
MIRT1257597	hsa-miR-1290	CLIP-seq
MIRT1257598	hsa-miR-190	CLIP-seq
MIRT1257599	hsa-miR-190b	CLIP-seq
MIRT1257600	hsa-miR-198	CLIP-seq
MIRT1257601	hsa-miR-200b	CLIP-seq
MIRT1257602	hsa-miR-200c	CLIP-seq
MIRT1257603	hsa-miR-3134	CLIP-seq
MIRT1257604	hsa-miR-3167	CLIP-seq
MIRT1257571	hsa-miR-3691-3p	CLIP-seq
MIRT1257605	hsa-miR-369-3p	CLIP-seq
MIRT1257606	hsa-miR-374a	CLIP-seq
MIRT1257607	hsa-miR-374b	CLIP-seq
MIRT1257608	hsa-miR-429	CLIP-seq
MIRT1257609	hsa-miR-4487	CLIP-seq
MIRT1257574	hsa-miR-4506	CLIP-seq
MIRT1257610	hsa-miR-4753-5p	CLIP-seq
MIRT1257577	hsa-miR-548p	CLIP-seq
MIRT1257578	hsa-miR-555	CLIP-seq
MIRT1257611	hsa-miR-629	CLIP-seq
MIRT1257612	hsa-miR-876-5p	CLIP-seq
MIRT2075899	hsa-miR-2964a-3p	CLIP-seq
MIRT2302517	hsa-miR-1225-5p	CLIP-seq
MIRT2302518	hsa-miR-1226	CLIP-seq
MIRT2302519	hsa-miR-1262	CLIP-seq
MIRT2302520	hsa-miR-1914	CLIP-seq
MIRT2302521	hsa-miR-2113	CLIP-seq
MIRT2302522	hsa-miR-218	CLIP-seq
MIRT1257584	hsa-miR-24	CLIP-seq
MIRT1257585	hsa-miR-2467-3p	CLIP-seq
MIRT1257586	hsa-miR-2467-5p	CLIP-seq
MIRT2302523	hsa-miR-3140-3p	CLIP-seq
MIRT2302524	hsa-miR-3177-3p	CLIP-seq
MIRT2302525	hsa-miR-324-5p	CLIP-seq
MIRT2302526	hsa-miR-329	CLIP-seq
MIRT2302527	hsa-miR-362-3p	CLIP-seq
MIRT2302528	hsa-miR-3661	CLIP-seq
MIRT2302529	hsa-miR-3941	CLIP-seq
MIRT2302530	hsa-miR-4325	CLIP-seq
MIRT2302531	hsa-miR-4464	CLIP-seq
MIRT2302532	hsa-miR-4659a-5p	CLIP-seq
MIRT2302533	hsa-miR-4659b-5p	CLIP-seq
MIRT2302534	hsa-miR-466	CLIP-seq
MIRT2302535	hsa-miR-4672	CLIP-seq
MIRT2302536	hsa-miR-4701-3p	CLIP-seq
MIRT2302537	hsa-miR-4722-3p	CLIP-seq
MIRT2302538	hsa-miR-4733-3p	CLIP-seq
MIRT2302539	hsa-miR-4748	CLIP-seq
MIRT2302540	hsa-miR-4769-3p	CLIP-seq
MIRT2302541	hsa-miR-4773	CLIP-seq
MIRT1257592	hsa-miR-545	CLIP-seq
MIRT1257578	hsa-miR-555	CLIP-seq
MIRT2302542	hsa-miR-572	CLIP-seq
MIRT2302543	hsa-miR-603	CLIP-seq
MIRT2302544	hsa-miR-631	CLIP-seq
MIRT2302545	hsa-miR-636	CLIP-seq
MIRT1257594	hsa-miR-922	CLIP-seq
MIRT2302546	hsa-miR-1343	CLIP-seq
MIRT2302531	hsa-miR-4464	CLIP-seq
MIRT1257589	hsa-miR-4736	CLIP-seq
MIRT2302539	hsa-miR-4748	CLIP-seq
MIRT2302547	hsa-miR-657	CLIP-seq
MIRT2457064	hsa-miR-188-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000159	Component	Protein phosphatase type 2A complex	IBA
GO:0000159	Component	Protein phosphatase type 2A complex	IEA
GO:0000159	Component	Protein phosphatase type 2A complex	NAS	10945473
GO:0005515	Function	Protein binding	IPI	19156129, 24126060, 25816751, 33961781
GO:0005829	Component	Cytosol	IBA
GO:0019888	Function	Protein phosphatase regulator activity	IBA
GO:0019888	Function	Protein phosphatase regulator activity	IEA
GO:0019888	Function	Protein phosphatase regulator activity	NAS	10945473

MIM	HGNC	e!Ensembl
605997	9306	ENSG00000074211

Q9Y2T4

Protein name

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform (IMYPNO1) (PP2A subunit B isoform B55-gamma) (PP2A subunit B isoform PR55-gamma) (PP2A subunit B isoform R2-gamma) (PP2A subunit B isoform gamma)

Protein function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment.

Family and domains

Sequence

MGEDTDTRKINHSFLRDHSYVTEADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNA
PHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKI
TERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSIS
VNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVY
SSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRD
YLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNN
FFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAW
HPAENIIAIAATNNLYIFQDKVNSDMH

Sequence length

447

Interactions

View interactions

	KEGG
	mRNA surveillance pathway Sphingolipid signaling pathway PI3K-Akt signaling pathway AMPK signaling pathway Adrenergic signaling in cardiomyocytes Hippo signaling pathway Tight junction T cell receptor signaling pathway Dopaminergic synapse Chagas disease Hepatitis C Human papillomavirus infection

PPP2R2C (protein phosphatase 2 regulatory subunit Bgamma)