EXD2 (exonuclease 3'-5' domain containing 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55218 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Exonuclease 3'-5' domain containing 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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EXD2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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C14orf114, EXDL2 |
Chromosome
Chromosome number
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14 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q24.1 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9NVH0 | ||||||||||
Protein name | Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) | ||||||||||
Protein function | Exonuclease that has both 3'-5' exoribonuclease and exodeoxyribonuclease activities, depending on the divalent metal cation used as cofactor (PubMed:29335528, PubMed:31127291). In presence of Mg(2+), only shows 3'-5' exoribonuclease activity, wh | ||||||||||
PDB | 6K17 , 6K18 , 6K19 , 6K1A , 6K1B , 6K1C , 6K1D , 6K1E | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 621 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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