RPRD1A (regulation of nuclear pre-mRNA domain containing 1A)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55197 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Regulation of nuclear pre-mRNA domain containing 1A |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RPRD1A |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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HsT3101, P15RS |
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Chromosome
Chromosome number
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18 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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18q12.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator of G(1)/S phase progression. This protein also |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q96P16 | |||||||||||||||
| Protein name | Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein) | |||||||||||||||
| Protein function | Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin | |||||||||||||||
| PDB | 4JXT , 4NAC | |||||||||||||||
| Family and domains |
Pfam
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| Sequence | ||||||||||||||||
| Sequence length | 312 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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