AKIRIN2 (akirin 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 55122 |
| Gene name | Akirin 2 |
| Gene symbol | AKIRIN2 |
| Synonyms (NCBI Gene) |
C6orf166FBI1dJ486L4.2
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| Chromosome | 6 |
| Chromosome location | 6q15 |
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miRNA
miRNA information provided by mirtarbase database.
291
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
42
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q53H80 | |
| Protein name | Akirin-2 | |
| Protein function | Molecular adapter that acts as a bridge between a variety of multiprotein complexes, and which is involved in embryonic development, immunity, myogenesis and brain development (PubMed:34711951). Plays a key role in nuclear protein degradation by | |
| PDB | 7NHT | |
| Family and domains | ||
| Tissue specificity | TISSUE SPECIFICITY: Widely expressed with the highest expression in peripheral blood leukocytes. {ECO:0000269|PubMed:18066067}. | |
| Sequence |
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| Sequence length | 203 | |
| Interactions | View interactions | |
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
16
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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