Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	55105
Gene name Gene Name - the full gene name approved by the HGNC.	G-patch domain containing 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	GPATCH2
Synonyms (NCBI Gene) Gene synonyms aliases	CT110, GPATC2, PPP1R30, Pfa1
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q41
Summary Summary of gene provided in NCBI Entrez Gene.	The gene encodes a nuclear factor that may play a role in spermatogenesis and in tumor growth during breast cancer. The encoded protein contains a G-patch domain with an RNA binding motif. Alternative splicing results in multiple transcript variants. [pro

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miRTarBase ID	miRNA	Experiments	Reference
MIRT020254	hsa-miR-130b-3p	Sequencing	20371350
MIRT028123	hsa-miR-93-5p	Sequencing	20371350
MIRT029984	hsa-miR-26b-5p	Microarray	19088304
MIRT1028228	hsa-miR-106a	CLIP-seq
MIRT1028229	hsa-miR-106b	CLIP-seq
MIRT1028230	hsa-miR-1207-5p	CLIP-seq
MIRT1028231	hsa-miR-1286	CLIP-seq
MIRT1028232	hsa-miR-17	CLIP-seq
MIRT1028233	hsa-miR-183	CLIP-seq
MIRT1028234	hsa-miR-20a	CLIP-seq
MIRT1028235	hsa-miR-20b	CLIP-seq
MIRT1028236	hsa-miR-219-2-3p	CLIP-seq
MIRT1028237	hsa-miR-2467-3p	CLIP-seq
MIRT1028238	hsa-miR-2964a-3p	CLIP-seq
MIRT1028239	hsa-miR-29a	CLIP-seq
MIRT1028240	hsa-miR-29b	CLIP-seq
MIRT1028241	hsa-miR-29c	CLIP-seq
MIRT1028242	hsa-miR-3169	CLIP-seq
MIRT1028243	hsa-miR-3609	CLIP-seq
MIRT1028244	hsa-miR-3647-3p	CLIP-seq
MIRT1028245	hsa-miR-3672	CLIP-seq
MIRT1028246	hsa-miR-3678-3p	CLIP-seq
MIRT1028247	hsa-miR-377	CLIP-seq
MIRT1028248	hsa-miR-4257	CLIP-seq
MIRT1028249	hsa-miR-4517	CLIP-seq
MIRT1028250	hsa-miR-4521	CLIP-seq
MIRT1028251	hsa-miR-4643	CLIP-seq
MIRT1028252	hsa-miR-4724-5p	CLIP-seq
MIRT1028253	hsa-miR-4736	CLIP-seq
MIRT1028254	hsa-miR-4763-3p	CLIP-seq
MIRT1028255	hsa-miR-4768-5p	CLIP-seq
MIRT1028256	hsa-miR-4786-3p	CLIP-seq
MIRT1028257	hsa-miR-4796-3p	CLIP-seq
MIRT1028258	hsa-miR-505	CLIP-seq
MIRT1028259	hsa-miR-514	CLIP-seq
MIRT1028260	hsa-miR-514b-3p	CLIP-seq
MIRT1028261	hsa-miR-519a	CLIP-seq
MIRT1028262	hsa-miR-519b-3p	CLIP-seq
MIRT1028263	hsa-miR-519c-3p	CLIP-seq
MIRT1028264	hsa-miR-519d	CLIP-seq
MIRT1028265	hsa-miR-548ah	CLIP-seq
MIRT1028266	hsa-miR-579	CLIP-seq
MIRT1028267	hsa-miR-605	CLIP-seq
MIRT1028268	hsa-miR-642b	CLIP-seq
MIRT1028269	hsa-miR-767-5p	CLIP-seq
MIRT1028270	hsa-miR-875-3p	CLIP-seq
MIRT1028271	hsa-miR-93	CLIP-seq
MIRT2005001	hsa-miR-3074-5p	CLIP-seq
MIRT2005002	hsa-miR-4421	CLIP-seq
MIRT2005003	hsa-miR-4456	CLIP-seq
MIRT2005004	hsa-miR-4738-3p	CLIP-seq
MIRT2005005	hsa-miR-4796-5p	CLIP-seq
MIRT2005006	hsa-miR-582-3p	CLIP-seq
MIRT1028267	hsa-miR-605	CLIP-seq
MIRT1028230	hsa-miR-1207-5p	CLIP-seq
MIRT1028231	hsa-miR-1286	CLIP-seq
MIRT2237711	hsa-miR-1323	CLIP-seq
MIRT1028233	hsa-miR-183	CLIP-seq
MIRT1028242	hsa-miR-3169	CLIP-seq
MIRT2237712	hsa-miR-338-5p	CLIP-seq
MIRT1028245	hsa-miR-3672	CLIP-seq
MIRT2237713	hsa-miR-4261	CLIP-seq
MIRT1028253	hsa-miR-4736	CLIP-seq
MIRT1028254	hsa-miR-4763-3p	CLIP-seq
MIRT2237714	hsa-miR-4765	CLIP-seq
MIRT1028255	hsa-miR-4768-5p	CLIP-seq
MIRT2237715	hsa-miR-494	CLIP-seq
MIRT2237716	hsa-miR-548o	CLIP-seq
MIRT1028267	hsa-miR-605	CLIP-seq
MIRT2005003	hsa-miR-4456	CLIP-seq
MIRT2005004	hsa-miR-4738-3p	CLIP-seq
MIRT2450531	hsa-miR-541	CLIP-seq
MIRT2005006	hsa-miR-582-3p	CLIP-seq
MIRT2450532	hsa-miR-654-5p	CLIP-seq
MIRT1028228	hsa-miR-106a	CLIP-seq
MIRT1028229	hsa-miR-106b	CLIP-seq
MIRT1028232	hsa-miR-17	CLIP-seq
MIRT1028234	hsa-miR-20a	CLIP-seq
MIRT1028235	hsa-miR-20b	CLIP-seq
MIRT1028237	hsa-miR-2467-3p	CLIP-seq
MIRT1028243	hsa-miR-3609	CLIP-seq
MIRT1028246	hsa-miR-3678-3p	CLIP-seq
MIRT1028248	hsa-miR-4257	CLIP-seq
MIRT1028257	hsa-miR-4796-3p	CLIP-seq
MIRT1028261	hsa-miR-519a	CLIP-seq
MIRT1028262	hsa-miR-519b-3p	CLIP-seq
MIRT1028263	hsa-miR-519c-3p	CLIP-seq
MIRT1028264	hsa-miR-519d	CLIP-seq
MIRT1028265	hsa-miR-548ah	CLIP-seq
MIRT1028266	hsa-miR-579	CLIP-seq
MIRT1028271	hsa-miR-93	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA
GO:0005515	Function	Protein binding	IPI	28514442, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005730	Component	Nucleolus	IEA
GO:0016607	Component	Nuclear speck	IDA
GO:0016607	Component	Nuclear speck	IEA

MIM	HGNC	e!Ensembl
616836	25499	ENSG00000092978

Protein

UniProt ID

Q9NW75

Protein name

G patch domain-containing protein 2

Protein function

Enhances the ATPase activity of DHX15 in vitro.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01585	G-patch	467 → 511	G-patch domain	Family

Tissue specificity

TISSUE SPECIFICITY: Testis. {ECO:0000269|PubMed:19432882}.

Sequence

MFGAAGRQPIGAPAAGNSWHFSRTMEELVHDLVSALEESSEQARGGFAETGDHSRSISCP
LKRQARKRRGRKRRSYNVHHPWETGHCLSEGSDSSLEEPSKDYRENHNNNKKDHSDSDDQ
MLVAKRRPSSNLNNNVRGKRPLWHESDFAVDNVGNRTLRRRRKVKRMAVDLPQDISNKRT
MTQPPEGCRDQDMDSDRAYQYQEFTKNKVKKRKLKIIRQGPKIQDEGVVLESEETNQTNK
DKMECEEQKVSDELMSESDSSSLSSTDAGLFTNDEGRQGDDEQSDWFYEKESGGACGITG
VVPWWEKEDPTELDKNVPDPVFESILTGSFPLMSHPSRRGFQARLSRLHGMSSKNIKKSG
GTPTSMVPIPGPVGNKRMVHFSPDSHHHDHWFSPGARTEHDQHQLLRDNRAERGHKKNCS
VRTASRQTSMHLGSLCTGDIKRRRKAAPLPGPTTAGFVGENAQPILENNIGNRMLQNMGW
TPGSGLGRDGKGISEPIQAMQRPKGLGLGFPLPKSTSATTTPNAGKSA

Sequence length

528

Interactions

View interactions

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Atrial Fibrillation	Atrial fibrillation	N/A	N/A	GWAS
Intracranial Aneurysm	Intracranial aneurysm	N/A	N/A	GWAS
Long QT Syndrome	long qt syndrome	N/A	N/A	ClinVar

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Breast Neoplasms	Associate	19432882
Hereditary Breast and Ovarian Cancer Syndrome	Associate	19432882
Neoplasms	Associate	19432882

GPATCH2 (G-patch domain containing 2)