RALGPS2 (Ral GEF with PH domain and SH3 binding motif 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 55103 |
| Gene name | Ral GEF with PH domain and SH3 binding motif 2 |
| Gene symbol | RALGPS2 |
| Synonyms (NCBI Gene) |
dJ595C2.1
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| Chromosome | 1 |
| Chromosome location | 1q25.2 |
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miRNA
miRNA information provided by mirtarbase database.
408
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q86X27 | |||||||||||||||
| Protein name | Ras-specific guanine nucleotide-releasing factor RalGPS2 (Ral GEF with PH domain and SH3-binding motif 2) (RalA exchange factor RalGPS2) | |||||||||||||||
| Protein function | Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity). | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 583 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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