WDR70 (WD repeat domain 70)

Gene

• Entrez ID: 55100
• Gene name: WD repeat domain 70
• Gene symbol: WDR70
• Synonyms (NCBI Gene): -
• Chromosome: 5
• Chromosome location: 5p13.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT649460	hsa-miR-5193	HITS-CLIP	23824327
MIRT649459	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT649458	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT649457	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT649456	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT649455	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT649454	hsa-miR-7152-3p	HITS-CLIP	23824327
MIRT649453	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT649452	hsa-miR-9-5p	HITS-CLIP	23824327
MIRT649451	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT649449	hsa-miR-6844	HITS-CLIP	23824327
MIRT649460	hsa-miR-5193	HITS-CLIP	23824327
MIRT649459	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT649458	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT649457	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT649456	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT649455	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT649454	hsa-miR-7152-3p	HITS-CLIP	23824327
MIRT649453	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT649452	hsa-miR-9-5p	HITS-CLIP	23824327
MIRT649451	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT649449	hsa-miR-6844	HITS-CLIP	23824327
MIRT1491273	hsa-miR-3646	CLIP-seq
MIRT1491274	hsa-miR-3662	CLIP-seq
MIRT1491275	hsa-miR-433	CLIP-seq
MIRT1491276	hsa-miR-4775	CLIP-seq
MIRT1491277	hsa-miR-548c-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005634	Component	Nucleus	IBA
GO:0005654	Component	Nucleoplasm	TAS
GO:0019899	Function	Enzyme binding	IPI	23382074
GO:0035861	Component	Site of double-strand break	IBA

Other IDs

• MIM: 617233
• HGNC: 25495
• e!Ensembl: ENSG00000082068

Protein

• UniProt ID: Q9NW82
• Protein name: WD repeat-containing protein 70
• PDB: 6ZYM, 7A5P, 8I0W
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00400	WD40	168 → 210	WD domain, G-beta repeat	Repeat
  PF00400	WD40	323 → 360	WD domain, G-beta repeat	Repeat
  PF00400	WD40	365 → 406	WD domain, G-beta repeat	Repeat

• Sequence:

  MERSGPSEVTGSDASGPDPQLAVTMGFTGFGKKARTFDLEAMFEQTRRTAVERSRKTLEA
  REKEEEMNREKELRRQNEDIEPTSSRSNVVRDCSKSSSRDTSSSESEQSSDSSDDELIGP
  PLPPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEEEEEEEEEEENPVHKIPDSHEITLKH
  GTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNT
  GDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFM
  TCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWD
  RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGL
  PTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQRVYEIDITDASVVRCLWH
  PKLNQIMVGTGNGLAKVYYDPNKSQRGAKLCVVKTQRKAKQAETLTQDYIITPHALPMFR
  EPRQRSTRKQLEKDRLDPLKSHKPEPPVAGPGRGGRVGTHGGTLSSYIVKNIALDKTDDS
  NPREAILRHAKAAEDSPYWVSPAYSKTQPKTMFAQVESDDEEAKNEPEWKKRKI

• Sequence length: 654