Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	55083
Gene name Gene Name - the full gene name approved by the HGNC.	Kinesin family member 26B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	KIF26B
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q44
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is an intracellular motor protein thought to transport organelles along microtubules. The encoded protein is required for kidney development. Elevated levels of this protein have been found in some breast and colorectal ca

Show/Hide all(79)

miRTarBase ID	miRNA	Experiments	Reference
MIRT667705	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT656874	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT656873	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT656872	hsa-miR-3944-3p	HITS-CLIP	23824327
MIRT667704	hsa-miR-4279	HITS-CLIP	23824327
MIRT656871	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT656874	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT656873	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT656872	hsa-miR-3944-3p	HITS-CLIP	23824327
MIRT656871	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT536468	hsa-miR-634	PAR-CLIP	22012620
MIRT536467	hsa-miR-4690-3p	PAR-CLIP	22012620
MIRT536466	hsa-miR-5685	PAR-CLIP	22012620
MIRT536464	hsa-miR-4530	PAR-CLIP	22012620
MIRT732249	hsa-miR-20a-5p	Luciferase reporter assay, qRT-PCR, Western blot	27499703
MIRT732249	hsa-miR-20a-5p	Luciferase reporter assay, qRT-PCR, Western blot	27499703
MIRT667705	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT656874	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT656873	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT656872	hsa-miR-3944-3p	HITS-CLIP	23824327
MIRT667704	hsa-miR-4279	HITS-CLIP	23824327
MIRT656871	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT656874	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT656873	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT656872	hsa-miR-3944-3p	HITS-CLIP	23824327
MIRT656871	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT536468	hsa-miR-634	PAR-CLIP	22012620
MIRT536467	hsa-miR-4690-3p	PAR-CLIP	22012620
MIRT536466	hsa-miR-5685	PAR-CLIP	22012620
MIRT536464	hsa-miR-4530	PAR-CLIP	22012620
MIRT1094412	hsa-miR-1253	CLIP-seq
MIRT1094413	hsa-miR-29a	CLIP-seq
MIRT1094414	hsa-miR-29b	CLIP-seq
MIRT1094415	hsa-miR-29c	CLIP-seq
MIRT1094416	hsa-miR-3158-3p	CLIP-seq
MIRT1094417	hsa-miR-451b	CLIP-seq
MIRT1094418	hsa-miR-4520a-3p	CLIP-seq
MIRT1094419	hsa-miR-4520b-3p	CLIP-seq
MIRT2025295	hsa-miR-3064-3p	CLIP-seq
MIRT2025296	hsa-miR-4715-3p	CLIP-seq
MIRT2025297	hsa-miR-499a-5p	CLIP-seq
MIRT2256568	hsa-miR-124	CLIP-seq
MIRT2256569	hsa-miR-2116	CLIP-seq
MIRT1094416	hsa-miR-3158-3p	CLIP-seq
MIRT2256570	hsa-miR-342-3p	CLIP-seq
MIRT2256571	hsa-miR-3924	CLIP-seq
MIRT2256572	hsa-miR-4274	CLIP-seq
MIRT2256573	hsa-miR-4277	CLIP-seq
MIRT2256574	hsa-miR-450b-5p	CLIP-seq
MIRT2256575	hsa-miR-4519	CLIP-seq
MIRT2256576	hsa-miR-4708-3p	CLIP-seq
MIRT2256577	hsa-miR-506	CLIP-seq
MIRT2256578	hsa-miR-513a-5p	CLIP-seq
MIRT2256579	hsa-miR-621	CLIP-seq
MIRT2256580	hsa-miR-622	CLIP-seq
MIRT1094413	hsa-miR-29a	CLIP-seq
MIRT1094414	hsa-miR-29b	CLIP-seq
MIRT1094415	hsa-miR-29c	CLIP-seq
MIRT2025295	hsa-miR-3064-3p	CLIP-seq
MIRT2025296	hsa-miR-4715-3p	CLIP-seq
MIRT2430433	hsa-miR-4731-3p	CLIP-seq
MIRT2430434	hsa-miR-4801	CLIP-seq
MIRT2025297	hsa-miR-499a-5p	CLIP-seq
MIRT2430435	hsa-miR-548l	CLIP-seq
MIRT2430436	hsa-miR-767-5p	CLIP-seq
MIRT1094413	hsa-miR-29a	CLIP-seq
MIRT1094414	hsa-miR-29b	CLIP-seq
MIRT1094415	hsa-miR-29c	CLIP-seq
MIRT2430433	hsa-miR-4731-3p	CLIP-seq
MIRT2430434	hsa-miR-4801	CLIP-seq
MIRT2430435	hsa-miR-548l	CLIP-seq
MIRT2430436	hsa-miR-767-5p	CLIP-seq
MIRT1094413	hsa-miR-29a	CLIP-seq
MIRT1094414	hsa-miR-29b	CLIP-seq
MIRT1094415	hsa-miR-29c	CLIP-seq
MIRT2430433	hsa-miR-4731-3p	CLIP-seq
MIRT2430434	hsa-miR-4801	CLIP-seq
MIRT2430435	hsa-miR-548l	CLIP-seq
MIRT2430436	hsa-miR-767-5p	CLIP-seq

Show/Hide all(11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003777	Function	Microtubule motor activity	IBA	21873635
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005871	Component	Kinesin complex	IBA	21873635
GO:0005874	Component	Microtubule	IBA	21873635
GO:0007018	Process	Microtubule-based movement	IBA	21873635
GO:0008017	Function	Microtubule binding	IBA	21873635
GO:0016887	Function	ATPase activity	IBA	21873635
GO:0022409	Process	Positive regulation of cell-cell adhesion	IEA
GO:0030010	Process	Establishment of cell polarity	IEA
GO:0072092	Process	Ureteric bud invasion	IEA

MIM	HGNC	e!Ensembl
614026	25484	ENSG00000162849

Protein

UniProt ID

Q2KJY2

Protein name

Kinesin-like protein KIF26B

Protein function

Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral inte

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00225	Kinesin	472 → 801	Kinesin motor domain	Domain

Sequence

MNSVAGNKERLAVSTRGKKYGVNEVCSPTKPAAPFSPESWYRKAYEESRAGSRPTPEGAG
SALGSSGTPSPGSGTSSPSSFTGSPGPASPGIGTSSPGSLGGSPGFGTGSPGSGSGGGSS
PGSDRGVWCENCNARLVELKRQALRLLLPGPFPGKDPAFSAVIHDKLQVPNTIRKAWNDR
DNRCDICATHLNQLKQEAIQMVLTLEQAAGSEHYDASPCSPPPLSNIPTLVGSRHVGGLQ
QPRDWAFVPAPCATSNYTGFANKHGSKPSSLGVSNGAEKKSGSPTHQAKVSLQMATSPSN
GNILNSVAIQAHQYLDGTWSLSRTNGVTLYPYQISQLMTESSREGLTEAVLNRYNADKPS
ACSVPASQGSCVASETSTGTSVAASFFARAAQKLNLSSKKKKHRPSTSSAAEPPLFATSF
SGILQTSPPPAPPCLLRAVNKVKDTPGLGKVKVMLRICSTLARDTSESSSFLKVDPRKKQ
ITLYDPLTCGGQNAFQKRGNQVPPKMFAFDAVFPQDASQAEVCAGTVAEVIQSVVNGADG
CVFCFGHAKLGKSYTMIGKDDSMQNLGIIPCAISWLFKLINERKEKTGARFSVRVSAVEV
WGKEENLRDLLSEVATGSLQDGQSPGVYLCEDPICGTQLQNQSELRAPTAEKAAFFLDAA
IASRRSHQQDCDEDDHRNSHVFFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCVKALS
KNREGGSGLCLSLSALGNVILALVNGSKHIPYKESKLAMLLRESLGNMNCRTTMIAHISA
AVGSYAETLSTIQIASRVLRMKKKKTKYTSSSSGGESSCEEGRMRRPTQLRPFHTRATVD
PDFPIAHLSSDPDYSSSSEQSCDTVIYIGPNGTALSDKELTDNEGPPDFVPIVPALQKTR
GDSRPAEAGEAAAGKSERDCLKCNTFAELQERLDCIDGSEEPSSFPFEELPAQFGPEQAS
RGPRLSQAAGASPLSESDKEDNGSEGQLTNREGPELPASKMQRSHSPVPAAAPAHSPSPA
SPRSVPGSSSQHSASPLVQSPSLQSSRESLNSCGFVEGKPRPMGSPRLGIASLSKTSEYK
PPSSPSQRCKVYTQKGVLPSPAPLPPSSKDSGVASRESLLQPEVRTPPVGMSPQVLKKSM
SAGSEGFPETPVDDEQQAATPSESKKEILSTTMVTVQQPLELNGEDELVFTLVEELTISG
VLDSGRPTSIISFNSDCSARALASGSRPVSIISSISEDLECYSSTAPVSEVSITQFLPLP
KMSLDEKAQDAGSRRSSISSWLSEMSAGSEGEQSCHSFIAQTCFGHGEAMAEPVASEFVS
SLQNTAVVCREKPKASPDNLLILSEMGDDSFNKAAPIKGCKISTVSKAMVTISNTANLSS
CEGYIPMKTNITVYPCIAMSPRNIQEPEAPTATPKAGPTLAQSRESKENSAKKEMKFEDP
WLKREEEVKKETAHPNEEGMMRCETATGPSNAETRAEQEQDGKPSPGDRLSSSSGEVSAS
PVTDNFRRVVDGCEMALPGLATQSPVHPNKSVKSSSLPRAFQKASRQEEPDSLSYYCAAE
TNGVGAASGTPPSKATLEGKVASPKHCVLARPKGTPPLPPVRKSSLDQKNRASPQHSASG
SGTSSPLNQPAAFPAGLPDEPSGKTKDASSSSKLFSAKLEQLASRSNSLGRATVSHYECL
SLERAESLSSVSSRLHAGKDGTMPRAGRSLGRSAGTSPPSSGASPKAGQSKISAVSRLLL
ASPRARGPSASTTKTLSFSTKSLPQAVGQGSSSPPGGKHTPWSTQSLSRNRSSGLASKLP
LRAVSGRISELLQGGAGARGLQLRAGPEAEARGGALAEDEPAAAHLLPSPYSKITPPRRP
HRCSSGHGSDNSSVLSGELPPAMGKTALFYHSGGSSGYESVMRDSEATGSASSAQDSTSE
NSSSVGGRCRSLKTPKKRSNPGSQRRRLIPALSLDTSSPVRKPPNSTGVRWVDGPLRSSP
RGLGEPFEIKVYEIDDVERLQRRRGGASKEAMCFNAKLKILEHRQQRIAEVRAKYEWLMK
ELEATKQYLMLDPNKWLSEFDLEQVWELDSLEYLEALECVTERLESRVNFCKAHLMMITC
FDITSRRR

Sequence length

2108

Interactions

View interactions

	KEGG		Reactome
	Motor proteins		COPI-dependent Golgi-to-ER retrograde traffic Kinesins

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Arthritis	Degenerative polyarthritis	rs1594890601, rs1594882933, rs184370809, rs776489319, rs1594883470	30664745
Glioma	Glioma	rs121909219, rs121909224, rs587776667, rs587776671, rs121909239, rs121909241, rs28933368, rs121913500, rs55863639, rs786201995, rs786202517, rs786201044, rs398123317, rs1057518425, rs121913499 View all (13 more)	19578366
Rheumatoid arthritis	Rheumatoid Arthritis	rs587776843	30251476

Show/Hide Unknown Diseases (3)

Disease term	Disease name	References	Source
Unknown
Ischemic stroke	Ischemic stroke	26718567	ClinVar
Schizophrenia	Schizophrenia		GWAS
Insomnia	Insomnia		GWAS

Show/Hide Text Mining Associations (19)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma	Associate	20651033
Anophthalmia with pulmonary hypoplasia	Associate	32799327
Breast Neoplasms	Stimulate	23585914
Breast Neoplasms	Associate	37551622
Carcinogenesis	Associate	23585914, 25652119
Colonic Neoplasms	Stimulate	37436127
Colorectal Neoplasms	Stimulate	25652119
Colorectal Neoplasms	Associate	27935967, 37436127
Leukemia Myeloid Acute	Associate	34579730
Medulloblastoma	Stimulate	35866054
Neoplasm Invasiveness	Stimulate	29880787
Neoplasms	Stimulate	25652119
Neoplasms	Associate	37436127
Neoplasms	Inhibit	37551622
Ovarian Neoplasms	Stimulate	29880787
Ovarian Neoplasms	Associate	32186777
Papillorenal syndrome	Associate	26571382
Recurrence	Associate	27935967
Vesico Ureteral Reflux	Associate	36417404

KIF26B (kinesin family member 26B)