ZWILCH (zwilch kinetochore protein)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 55055 |
| Gene name | Zwilch kinetochore protein |
| Gene symbol | ZWILCH |
| Synonyms (NCBI Gene) |
KNTC1APhZwilch
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| Chromosome | 15 |
| Chromosome location | 15q22.31 |
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miRNA
miRNA information provided by mirtarbase database.
523
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9H900 | ||||||||||
| Protein name | Protein zwilch homolog (hZwilch) | ||||||||||
| Protein function | Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machin | ||||||||||
| PDB | 3IF8 , 7QPG | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 591 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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