ZWILCH (zwilch kinetochore protein)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55055 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Zwilch kinetochore protein |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ZWILCH |
Synonyms (NCBI Gene)
Gene synonyms aliases
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KNTC1AP, hZwilch |
Chromosome
Chromosome number
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15 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q22.31 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9H900 | ||||||||||
Protein name | Protein zwilch homolog (hZwilch) | ||||||||||
Protein function | Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machin | ||||||||||
PDB | 3IF8 , 7QPG | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 591 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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