VPS37C (VPS37C subunit of ESCRT-I)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55048 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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VPS37C subunit of ESCRT-I |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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VPS37C |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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- |
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Chromosome
Chromosome number
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11 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11q12.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | A5D8V6 | ||||||||||
| Protein name | Vacuolar protein sorting-associated protein 37C (hVps37C) (ESCRT-I complex subunit VPS37C) | ||||||||||
| Protein function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. {ECO:0000269|PubMed:155095 | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 355 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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