Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55014
Gene name Gene Name - the full gene name approved by the HGNC.
Syntaxin 17
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
STX17
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
9q31.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT046119 hsa-miR-30b-5p CLASH 23622248
MIRT520887 hsa-miR-6769a-3p PAR-CLIP 23446348
MIRT520886 hsa-miR-512-3p PAR-CLIP 23446348
MIRT520885 hsa-miR-6801-3p PAR-CLIP 23446348
MIRT520884 hsa-miR-6810-3p PAR-CLIP 23446348
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000149 Function SNARE binding IBA
GO:0000149 Function SNARE binding IDA 23217709
GO:0000149 Function SNARE binding IEA
GO:0000421 Component Autophagosome membrane IBA
GO:0000421 Component Autophagosome membrane IDA 23217709, 26416964, 28306502
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
604204 11432 ENSG00000136874
Protein
UniProt ID P56962
Protein name Syntaxin-17
Protein function SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four al
PDB 4WY4 , 7BV4 , 7BV6
Family and domains
Sequence
MSEDEEKVKLRRLEPAIQKFIKIVIPTDLERLRKHQINIEKYQRCRIWDKLHEEHINAGR
TVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQF
NDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADLI
ELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALIG
GMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDKK
CS
Sequence length 302
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  SNARE interactions in vesicular transport
Autophagy - animal
  COPII-mediated vesicle transport
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Alopecia Areata Alopecia areata N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Alopecia Areata Associate 20596022, 29080678
Cardiomyopathies Associate 30584088
COVID 19 Associate 36394763
Depressive Disorder Major Associate 36394763
Down Syndrome Associate 31714914
Drug Related Side Effects and Adverse Reactions Associate 29445155
Glycogen Storage Disease Type II Associate 33799647
Lysosomal Storage Diseases Associate 29445155
Neoplasms Associate 37083075
Urinary Bladder Neoplasms Associate 37083075