Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55007
Gene name Gene Name - the full gene name approved by the HGNC.
Family with sequence similarity 118 member A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
FAM118A
Synonyms (NCBI Gene) Gene synonyms aliases
C22orf8
Chromosome Chromosome number
22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q13.31
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT023325 hsa-miR-122-5p Microarray 17612493
MIRT029381 hsa-miR-26b-5p Microarray 19088304
MIRT043956 hsa-miR-378a-3p CLASH 23622248
MIRT707705 hsa-miR-548c-3p HITS-CLIP 21572407
MIRT707704 hsa-miR-6732-3p HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 29892012, 31515488, 32296183
GO:0016021 Component Integral component of membrane IEA
GO:0042802 Function Identical protein binding IPI 25416956, 32296183
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
UniProt ID Q9NWS6
Protein name Protein FAM118A
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13289 SIR2_2 142 284 SIR2-like domain Family
Sequence
MDSVEKTTNRSEQKSRKFLKSLIRKQPQELLLVIGTGVSAAVAPGIPALCSWRSCIEAVI
EAAEQLEVLHPGDVAEFRRKVTKDRDLLVVAHDLIRKMSPRTGDAKPSFFQDCLMEVFDD
LEQHIRSPVVLQSILSLMDRGAMVLTTNYDNLLEAFGRRQNKPMESLDLKDKTKVLEWAR
GHMKYGVLHIHGLYTDPCGVVLDPSGYKDVTQDAEVMEVLQNLYRTKSFLFVGCGETLRD
QIFQALFLYSVPNKVDLEHYMLVLKENEDHFFKHQADMLLHGIK
VVSYGDCFDHFPGYVQ
DLATQICKQQSPDADRVDSTTLLGNACQDCAKRKLEENGIEVSKKRTQSDTDDAGGS
Sequence length 357
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Psoriasis Psoriasis rs281875215, rs587777763, rs281875213, rs281875212 26974007
Unknown
Disease term Disease name Evidence References Source
Crohn disease Crohn Disease 26974007 ClinVar
Colorectal Cancer Colorectal Cancer In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1. GWAS, CBGDA
Prostate cancer Prostate cancer Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population. GWAS, CBGDA
Dental caries Dental caries GWAS