Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	54976
Gene name	Adipose secreted signaling protein
Gene symbol	ADISSP
Synonyms (NCBI Gene)	C20orf27
Chromosome	20
Chromosome location	20p13

288

Show/Hide all (288)

miRTarBase ID	miRNA	Experiments	Reference
MIRT027009	hsa-miR-103a-3p	Sequencing	20371350
MIRT044398	hsa-miR-320a	CLASH	23622248
MIRT462625	hsa-miR-3646	PAR-CLIP	20371350
MIRT462624	hsa-miR-3714	PAR-CLIP	20371350
MIRT462623	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT462622	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT462621	hsa-miR-4688	PAR-CLIP	20371350
MIRT462620	hsa-miR-6743-5p	PAR-CLIP	20371350
MIRT462619	hsa-miR-4719	PAR-CLIP	20371350
MIRT462617	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT462616	hsa-miR-4493	PAR-CLIP	20371350
MIRT462612	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT462610	hsa-miR-885-3p	PAR-CLIP	20371350
MIRT462609	hsa-miR-1207-5p	PAR-CLIP	20371350
MIRT462608	hsa-miR-4763-3p	PAR-CLIP	20371350
MIRT462607	hsa-miR-6721-5p	PAR-CLIP	20371350
MIRT462606	hsa-miR-486-3p	PAR-CLIP	20371350
MIRT462605	hsa-miR-6126	PAR-CLIP	20371350
MIRT462625	hsa-miR-3646	PAR-CLIP	20371350
MIRT462624	hsa-miR-3714	PAR-CLIP	20371350
MIRT462623	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT462622	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT462619	hsa-miR-4719	PAR-CLIP	20371350
MIRT462617	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT462616	hsa-miR-4493	PAR-CLIP	20371350
MIRT462612	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT462610	hsa-miR-885-3p	PAR-CLIP	20371350
MIRT462609	hsa-miR-1207-5p	PAR-CLIP	20371350
MIRT462608	hsa-miR-4763-3p	PAR-CLIP	20371350
MIRT462607	hsa-miR-6721-5p	PAR-CLIP	20371350
MIRT462606	hsa-miR-486-3p	PAR-CLIP	20371350
MIRT462605	hsa-miR-6126	PAR-CLIP	20371350
MIRT462625	hsa-miR-3646	PAR-CLIP	23592263
MIRT462624	hsa-miR-3714	PAR-CLIP	23592263
MIRT462623	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT462622	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT462621	hsa-miR-4688	PAR-CLIP	23592263
MIRT462620	hsa-miR-6743-5p	PAR-CLIP	23592263
MIRT462619	hsa-miR-4719	PAR-CLIP	23592263
MIRT462618	hsa-miR-4257	PAR-CLIP	23592263
MIRT462617	hsa-miR-605-3p	PAR-CLIP	23592263
MIRT462616	hsa-miR-4493	PAR-CLIP	23592263
MIRT462615	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT462614	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT462613	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT462612	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT462611	hsa-miR-6853-5p	PAR-CLIP	23592263
MIRT462610	hsa-miR-885-3p	PAR-CLIP	23592263
MIRT462609	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT462608	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT462607	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT462606	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT462605	hsa-miR-6126	PAR-CLIP	23592263
MIRT462625	hsa-miR-3646	PAR-CLIP	20371350
MIRT462624	hsa-miR-3714	PAR-CLIP	20371350
MIRT462623	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT462622	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT462621	hsa-miR-4688	PAR-CLIP	20371350
MIRT462620	hsa-miR-6743-5p	PAR-CLIP	20371350
MIRT462619	hsa-miR-4719	PAR-CLIP	20371350
MIRT462617	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT462616	hsa-miR-4493	PAR-CLIP	20371350
MIRT462612	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT462610	hsa-miR-885-3p	PAR-CLIP	20371350
MIRT462609	hsa-miR-1207-5p	PAR-CLIP	20371350
MIRT462608	hsa-miR-4763-3p	PAR-CLIP	20371350
MIRT462607	hsa-miR-6721-5p	PAR-CLIP	20371350
MIRT462606	hsa-miR-486-3p	PAR-CLIP	20371350
MIRT462605	hsa-miR-6126	PAR-CLIP	20371350
MIRT462625	hsa-miR-3646	PAR-CLIP	20371350
MIRT462624	hsa-miR-3714	PAR-CLIP	20371350
MIRT462623	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT462622	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT462619	hsa-miR-4719	PAR-CLIP	20371350
MIRT462617	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT462616	hsa-miR-4493	PAR-CLIP	20371350
MIRT462612	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT462610	hsa-miR-885-3p	PAR-CLIP	20371350
MIRT462609	hsa-miR-1207-5p	PAR-CLIP	20371350
MIRT462608	hsa-miR-4763-3p	PAR-CLIP	20371350
MIRT462607	hsa-miR-6721-5p	PAR-CLIP	20371350
MIRT462606	hsa-miR-486-3p	PAR-CLIP	20371350
MIRT462605	hsa-miR-6126	PAR-CLIP	20371350
MIRT462625	hsa-miR-3646	PAR-CLIP	23592263
MIRT462624	hsa-miR-3714	PAR-CLIP	23592263
MIRT462623	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT462622	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT462621	hsa-miR-4688	PAR-CLIP	23592263
MIRT462620	hsa-miR-6743-5p	PAR-CLIP	23592263
MIRT462619	hsa-miR-4719	PAR-CLIP	23592263
MIRT462618	hsa-miR-4257	PAR-CLIP	23592263
MIRT462617	hsa-miR-605-3p	PAR-CLIP	23592263
MIRT462616	hsa-miR-4493	PAR-CLIP	23592263
MIRT462615	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT462614	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT462613	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT462612	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT462611	hsa-miR-6853-5p	PAR-CLIP	23592263
MIRT462610	hsa-miR-885-3p	PAR-CLIP	23592263
MIRT462609	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT462608	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT462607	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT462606	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT462605	hsa-miR-6126	PAR-CLIP	23592263
MIRT843884	hsa-miR-103a	CLIP-seq
MIRT843885	hsa-miR-107	CLIP-seq
MIRT843886	hsa-miR-1288	CLIP-seq
MIRT843887	hsa-miR-1321	CLIP-seq
MIRT843888	hsa-miR-1324	CLIP-seq
MIRT843889	hsa-miR-1470	CLIP-seq
MIRT843890	hsa-miR-1827	CLIP-seq
MIRT843891	hsa-miR-3130-3p	CLIP-seq
MIRT843892	hsa-miR-3138	CLIP-seq
MIRT843893	hsa-miR-3144-5p	CLIP-seq
MIRT843894	hsa-miR-3162-5p	CLIP-seq
MIRT843895	hsa-miR-3165	CLIP-seq
MIRT843896	hsa-miR-3184	CLIP-seq
MIRT843897	hsa-miR-3191	CLIP-seq
MIRT843898	hsa-miR-3199	CLIP-seq
MIRT843899	hsa-miR-3667-3p	CLIP-seq
MIRT843900	hsa-miR-3675-5p	CLIP-seq
MIRT843901	hsa-miR-4287	CLIP-seq
MIRT843902	hsa-miR-4290	CLIP-seq
MIRT843903	hsa-miR-4447	CLIP-seq
MIRT843904	hsa-miR-4469	CLIP-seq
MIRT843905	hsa-miR-4472	CLIP-seq
MIRT843906	hsa-miR-4488	CLIP-seq
MIRT843907	hsa-miR-4492	CLIP-seq
MIRT843908	hsa-miR-4498	CLIP-seq
MIRT843909	hsa-miR-4499	CLIP-seq
MIRT843910	hsa-miR-4505	CLIP-seq
MIRT843911	hsa-miR-4506	CLIP-seq
MIRT843912	hsa-miR-4519	CLIP-seq
MIRT843913	hsa-miR-4520a-3p	CLIP-seq
MIRT843914	hsa-miR-4649-3p	CLIP-seq
MIRT843915	hsa-miR-4649-5p	CLIP-seq
MIRT843916	hsa-miR-4651	CLIP-seq
MIRT843917	hsa-miR-4652-5p	CLIP-seq
MIRT843918	hsa-miR-4667-3p	CLIP-seq
MIRT843919	hsa-miR-4667-5p	CLIP-seq
MIRT843920	hsa-miR-4685-3p	CLIP-seq
MIRT843921	hsa-miR-4697-5p	CLIP-seq
MIRT843922	hsa-miR-4700-5p	CLIP-seq
MIRT843923	hsa-miR-4708-3p	CLIP-seq
MIRT843924	hsa-miR-4722-5p	CLIP-seq
MIRT843925	hsa-miR-4728-5p	CLIP-seq
MIRT843926	hsa-miR-4731-5p	CLIP-seq
MIRT843927	hsa-miR-4739	CLIP-seq
MIRT843928	hsa-miR-4756-5p	CLIP-seq
MIRT843929	hsa-miR-4768-3p	CLIP-seq
MIRT843930	hsa-miR-4786-3p	CLIP-seq
MIRT843931	hsa-miR-4787-5p	CLIP-seq
MIRT843932	hsa-miR-491-5p	CLIP-seq
MIRT843933	hsa-miR-544b	CLIP-seq
MIRT843934	hsa-miR-608	CLIP-seq
MIRT843935	hsa-miR-642a	CLIP-seq
MIRT843936	hsa-miR-671-5p	CLIP-seq
MIRT843937	hsa-miR-762	CLIP-seq
MIRT843938	hsa-miR-802	CLIP-seq
MIRT843884	hsa-miR-103a	CLIP-seq
MIRT843885	hsa-miR-107	CLIP-seq
MIRT1950091	hsa-miR-1273d	CLIP-seq
MIRT843886	hsa-miR-1288	CLIP-seq
MIRT843887	hsa-miR-1321	CLIP-seq
MIRT843889	hsa-miR-1470	CLIP-seq
MIRT843891	hsa-miR-3130-3p	CLIP-seq
MIRT843892	hsa-miR-3138	CLIP-seq
MIRT843893	hsa-miR-3144-5p	CLIP-seq
MIRT843894	hsa-miR-3162-5p	CLIP-seq
MIRT843895	hsa-miR-3165	CLIP-seq
MIRT843896	hsa-miR-3184	CLIP-seq
MIRT843897	hsa-miR-3191	CLIP-seq
MIRT843898	hsa-miR-3199	CLIP-seq
MIRT843900	hsa-miR-3675-5p	CLIP-seq
MIRT1950092	hsa-miR-3922-5p	CLIP-seq
MIRT843901	hsa-miR-4287	CLIP-seq
MIRT843903	hsa-miR-4447	CLIP-seq
MIRT843904	hsa-miR-4469	CLIP-seq
MIRT843905	hsa-miR-4472	CLIP-seq
MIRT843906	hsa-miR-4488	CLIP-seq
MIRT843907	hsa-miR-4492	CLIP-seq
MIRT843908	hsa-miR-4498	CLIP-seq
MIRT843910	hsa-miR-4505	CLIP-seq
MIRT843911	hsa-miR-4506	CLIP-seq
MIRT843912	hsa-miR-4519	CLIP-seq
MIRT843913	hsa-miR-4520a-3p	CLIP-seq
MIRT843915	hsa-miR-4649-5p	CLIP-seq
MIRT843916	hsa-miR-4651	CLIP-seq
MIRT843917	hsa-miR-4652-5p	CLIP-seq
MIRT843918	hsa-miR-4667-3p	CLIP-seq
MIRT843919	hsa-miR-4667-5p	CLIP-seq
MIRT843920	hsa-miR-4685-3p	CLIP-seq
MIRT843921	hsa-miR-4697-5p	CLIP-seq
MIRT843922	hsa-miR-4700-5p	CLIP-seq
MIRT843923	hsa-miR-4708-3p	CLIP-seq
MIRT1950093	hsa-miR-4717-5p	CLIP-seq
MIRT843924	hsa-miR-4722-5p	CLIP-seq
MIRT843926	hsa-miR-4731-5p	CLIP-seq
MIRT1950094	hsa-miR-4733-5p	CLIP-seq
MIRT843927	hsa-miR-4739	CLIP-seq
MIRT1950095	hsa-miR-4753-5p	CLIP-seq
MIRT843928	hsa-miR-4756-5p	CLIP-seq
MIRT843929	hsa-miR-4768-3p	CLIP-seq
MIRT843930	hsa-miR-4786-3p	CLIP-seq
MIRT843931	hsa-miR-4787-5p	CLIP-seq
MIRT1950096	hsa-miR-4795-5p	CLIP-seq
MIRT843932	hsa-miR-491-5p	CLIP-seq
MIRT1950097	hsa-miR-548aa	CLIP-seq
MIRT1950098	hsa-miR-548ac	CLIP-seq
MIRT1950099	hsa-miR-548ae	CLIP-seq
MIRT1950100	hsa-miR-548aj	CLIP-seq
MIRT1950101	hsa-miR-548am	CLIP-seq
MIRT1950102	hsa-miR-548d-3p	CLIP-seq
MIRT1950103	hsa-miR-548x	CLIP-seq
MIRT1950104	hsa-miR-548z	CLIP-seq
MIRT843934	hsa-miR-608	CLIP-seq
MIRT1950105	hsa-miR-660	CLIP-seq
MIRT843936	hsa-miR-671-5p	CLIP-seq
MIRT843937	hsa-miR-762	CLIP-seq
MIRT843938	hsa-miR-802	CLIP-seq
MIRT2188118	hsa-miR-1180	CLIP-seq
MIRT1950091	hsa-miR-1273d	CLIP-seq
MIRT843886	hsa-miR-1288	CLIP-seq
MIRT2188119	hsa-miR-1289	CLIP-seq
MIRT843890	hsa-miR-1827	CLIP-seq
MIRT2188120	hsa-miR-2114	CLIP-seq
MIRT843893	hsa-miR-3144-5p	CLIP-seq
MIRT843896	hsa-miR-3184	CLIP-seq
MIRT843897	hsa-miR-3191	CLIP-seq
MIRT843898	hsa-miR-3199	CLIP-seq
MIRT2188121	hsa-miR-339-5p	CLIP-seq
MIRT843903	hsa-miR-4447	CLIP-seq
MIRT2188122	hsa-miR-4456	CLIP-seq
MIRT843905	hsa-miR-4472	CLIP-seq
MIRT843906	hsa-miR-4488	CLIP-seq
MIRT843907	hsa-miR-4492	CLIP-seq
MIRT843908	hsa-miR-4498	CLIP-seq
MIRT843909	hsa-miR-4499	CLIP-seq
MIRT843910	hsa-miR-4505	CLIP-seq
MIRT843914	hsa-miR-4649-3p	CLIP-seq
MIRT843916	hsa-miR-4651	CLIP-seq
MIRT843917	hsa-miR-4652-5p	CLIP-seq
MIRT2188123	hsa-miR-4659a-3p	CLIP-seq
MIRT2188124	hsa-miR-4659b-3p	CLIP-seq
MIRT843919	hsa-miR-4667-5p	CLIP-seq
MIRT843921	hsa-miR-4697-5p	CLIP-seq
MIRT843922	hsa-miR-4700-5p	CLIP-seq
MIRT843924	hsa-miR-4722-5p	CLIP-seq
MIRT843926	hsa-miR-4731-5p	CLIP-seq
MIRT843929	hsa-miR-4768-3p	CLIP-seq
MIRT2188125	hsa-miR-541	CLIP-seq
MIRT843933	hsa-miR-544b	CLIP-seq
MIRT1950097	hsa-miR-548aa	CLIP-seq
MIRT1950098	hsa-miR-548ac	CLIP-seq
MIRT1950099	hsa-miR-548ae	CLIP-seq
MIRT1950100	hsa-miR-548aj	CLIP-seq
MIRT1950101	hsa-miR-548am	CLIP-seq
MIRT1950102	hsa-miR-548d-3p	CLIP-seq
MIRT1950103	hsa-miR-548x	CLIP-seq
MIRT1950104	hsa-miR-548z	CLIP-seq
MIRT843934	hsa-miR-608	CLIP-seq
MIRT2188126	hsa-miR-654-5p	CLIP-seq
MIRT1950105	hsa-miR-660	CLIP-seq
MIRT843937	hsa-miR-762	CLIP-seq
MIRT843900	hsa-miR-3675-5p	CLIP-seq
MIRT843911	hsa-miR-4506	CLIP-seq
MIRT843923	hsa-miR-4708-3p	CLIP-seq
MIRT843900	hsa-miR-3675-5p	CLIP-seq
MIRT843911	hsa-miR-4506	CLIP-seq
MIRT843923	hsa-miR-4708-3p	CLIP-seq
MIRT843887	hsa-miR-1321	CLIP-seq
MIRT843890	hsa-miR-1827	CLIP-seq
MIRT843896	hsa-miR-3184	CLIP-seq
MIRT2492035	hsa-miR-4419a	CLIP-seq
MIRT2492036	hsa-miR-4510	CLIP-seq
MIRT843925	hsa-miR-4728-5p	CLIP-seq
MIRT843927	hsa-miR-4739	CLIP-seq
MIRT843928	hsa-miR-4756-5p	CLIP-seq
MIRT1950096	hsa-miR-4795-5p	CLIP-seq
MIRT843887	hsa-miR-1321	CLIP-seq
MIRT843890	hsa-miR-1827	CLIP-seq
MIRT843896	hsa-miR-3184	CLIP-seq
MIRT2492035	hsa-miR-4419a	CLIP-seq
MIRT2492036	hsa-miR-4510	CLIP-seq
MIRT843925	hsa-miR-4728-5p	CLIP-seq
MIRT843927	hsa-miR-4739	CLIP-seq
MIRT843928	hsa-miR-4756-5p	CLIP-seq
MIRT1950096	hsa-miR-4795-5p	CLIP-seq

Show/Hide all (9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005575	Component	Cellular_component	ND
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	ISS
GO:0008157	Function	Protein phosphatase 1 binding	IDA	32024300
GO:0010739	Process	Positive regulation of protein kinase A signaling	ISS
GO:0030511	Process	Positive regulation of transforming growth factor beta receptor signaling pathway	IMP	32024300
GO:0042593	Process	Glucose homeostasis	ISS
GO:1901224	Process	Positive regulation of non-canonical NF-kappaB signal transduction	IMP	32024300
GO:1990845	Process	Adaptive thermogenesis	ISS

MIM	HGNC	e!Ensembl
620373	15873	ENSG00000101220

Q9GZN8

Protein name

Adipose-secreted signaling protein

Protein function

Adipocyte-secreted protein (adipokine) that acts as a key regulator for white adipose tissue (WAT) thermogenesis and glucose homeostasis at least in part through activation of protein kinase A (PKA).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15006	DUF4517	28 → 173	Domain of unknown function (DUF4517)	Family

Sequence

MAAANKGNKPRVRSIRFAAGHDAEGSHSHVHFDEKLHDSVVMVTQESDSSFLVKVGFLKI
LHRYEITFTLPPVHRLSKDVREAPVPSLHLKLLSVVPVPEGYSVKCEYSAHKEGVLKEEI
LLACEGGTGTCVRVTVQARVMDRHHGTPMLLDGVKCVGAELEYDSEHSDWHGFD

Sequence length

174

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
COLONIC NEOPLASM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

ADISSP (adipose secreted signaling protein)