Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	54965
Gene name Gene Name - the full gene name approved by the HGNC.	Phosphatidylinositol glycan anchor biosynthesis class X
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PIGX
Synonyms (NCBI Gene) Gene synonyms aliases	PIG-X
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q29
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors du

Show/Hide all(236)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024277	hsa-miR-215-5p	Microarray	19074876
MIRT026837	hsa-miR-192-5p	Microarray	19074876
MIRT031052	hsa-miR-21-5p	Microarray	18591254
MIRT1233644	hsa-miR-1182	CLIP-seq
MIRT1233645	hsa-miR-1193	CLIP-seq
MIRT1233646	hsa-miR-1206	CLIP-seq
MIRT1233647	hsa-miR-122	CLIP-seq
MIRT1233648	hsa-miR-1270	CLIP-seq
MIRT1233649	hsa-miR-1307	CLIP-seq
MIRT1233650	hsa-miR-130a	CLIP-seq
MIRT1233651	hsa-miR-130b	CLIP-seq
MIRT1233652	hsa-miR-142-3p	CLIP-seq
MIRT1233653	hsa-miR-1913	CLIP-seq
MIRT1233654	hsa-miR-197	CLIP-seq
MIRT1233655	hsa-miR-1976	CLIP-seq
MIRT1233656	hsa-miR-2276	CLIP-seq
MIRT1233657	hsa-miR-2392	CLIP-seq
MIRT1233658	hsa-miR-301a	CLIP-seq
MIRT1233659	hsa-miR-301b	CLIP-seq
MIRT1233660	hsa-miR-3121-5p	CLIP-seq
MIRT1233661	hsa-miR-3127-3p	CLIP-seq
MIRT1233662	hsa-miR-3152-3p	CLIP-seq
MIRT1233663	hsa-miR-3170	CLIP-seq
MIRT1233664	hsa-miR-3194-3p	CLIP-seq
MIRT1233665	hsa-miR-320e	CLIP-seq
MIRT1233666	hsa-miR-324-3p	CLIP-seq
MIRT1233667	hsa-miR-3606	CLIP-seq
MIRT1233668	hsa-miR-3666	CLIP-seq
MIRT1233669	hsa-miR-3679-3p	CLIP-seq
MIRT1233670	hsa-miR-411	CLIP-seq
MIRT1233671	hsa-miR-4279	CLIP-seq
MIRT1233672	hsa-miR-4284	CLIP-seq
MIRT1233673	hsa-miR-4295	CLIP-seq
MIRT1233674	hsa-miR-4297	CLIP-seq
MIRT1233675	hsa-miR-4497	CLIP-seq
MIRT1233676	hsa-miR-4524	CLIP-seq
MIRT1233677	hsa-miR-4531	CLIP-seq
MIRT1233678	hsa-miR-454	CLIP-seq
MIRT1233679	hsa-miR-4638-5p	CLIP-seq
MIRT1233680	hsa-miR-4659a-3p	CLIP-seq
MIRT1233681	hsa-miR-4659b-3p	CLIP-seq
MIRT1233682	hsa-miR-4662a-5p	CLIP-seq
MIRT1233683	hsa-miR-4671-3p	CLIP-seq
MIRT1233684	hsa-miR-4676-5p	CLIP-seq
MIRT1233685	hsa-miR-4695-3p	CLIP-seq
MIRT1233686	hsa-miR-4777-5p	CLIP-seq
MIRT1233687	hsa-miR-4778-3p	CLIP-seq
MIRT1233688	hsa-miR-5096	CLIP-seq
MIRT1233689	hsa-miR-518d-5p	CLIP-seq
MIRT1233690	hsa-miR-519b-5p	CLIP-seq
MIRT1233691	hsa-miR-519c-5p	CLIP-seq
MIRT1233692	hsa-miR-520c-5p	CLIP-seq
MIRT1233693	hsa-miR-526a	CLIP-seq
MIRT1233694	hsa-miR-548a-5p	CLIP-seq
MIRT1233695	hsa-miR-548ab	CLIP-seq
MIRT1233696	hsa-miR-548ak	CLIP-seq
MIRT1233697	hsa-miR-548b-5p	CLIP-seq
MIRT1233698	hsa-miR-548c-5p	CLIP-seq
MIRT1233699	hsa-miR-548d-5p	CLIP-seq
MIRT1233700	hsa-miR-548h	CLIP-seq
MIRT1233701	hsa-miR-548i	CLIP-seq
MIRT1233702	hsa-miR-548j	CLIP-seq
MIRT1233703	hsa-miR-548n	CLIP-seq
MIRT1233704	hsa-miR-548t	CLIP-seq
MIRT1233705	hsa-miR-548w	CLIP-seq
MIRT1233706	hsa-miR-548y	CLIP-seq
MIRT1233707	hsa-miR-559	CLIP-seq
MIRT1233708	hsa-miR-575	CLIP-seq
MIRT1233709	hsa-miR-577	CLIP-seq
MIRT1233710	hsa-miR-620	CLIP-seq
MIRT1233711	hsa-miR-1185	CLIP-seq
MIRT1233645	hsa-miR-1193	CLIP-seq
MIRT1233647	hsa-miR-122	CLIP-seq
MIRT1233712	hsa-miR-1279	CLIP-seq
MIRT1233653	hsa-miR-1913	CLIP-seq
MIRT1233655	hsa-miR-1976	CLIP-seq
MIRT1233713	hsa-miR-2114	CLIP-seq
MIRT1233714	hsa-miR-2278	CLIP-seq
MIRT1233657	hsa-miR-2392	CLIP-seq
MIRT1233715	hsa-miR-300	CLIP-seq
MIRT1233660	hsa-miR-3121-5p	CLIP-seq
MIRT1233662	hsa-miR-3152-3p	CLIP-seq
MIRT1233716	hsa-miR-3159	CLIP-seq
MIRT1233663	hsa-miR-3170	CLIP-seq
MIRT1233666	hsa-miR-324-3p	CLIP-seq
MIRT1233717	hsa-miR-3605-5p	CLIP-seq
MIRT1233718	hsa-miR-3679-5p	CLIP-seq
MIRT1233719	hsa-miR-381	CLIP-seq
MIRT1233720	hsa-miR-410	CLIP-seq
MIRT1233721	hsa-miR-4272	CLIP-seq
MIRT1233722	hsa-miR-4276	CLIP-seq
MIRT1233723	hsa-miR-4302	CLIP-seq
MIRT1233724	hsa-miR-4328	CLIP-seq
MIRT1233725	hsa-miR-4661-3p	CLIP-seq
MIRT1233682	hsa-miR-4662a-5p	CLIP-seq
MIRT1233726	hsa-miR-4666-3p	CLIP-seq
MIRT1233684	hsa-miR-4676-5p	CLIP-seq
MIRT1233727	hsa-miR-4760-3p	CLIP-seq
MIRT1233728	hsa-miR-4776-3p	CLIP-seq
MIRT1233729	hsa-miR-4789-5p	CLIP-seq
MIRT1233730	hsa-miR-4795-3p	CLIP-seq
MIRT1233688	hsa-miR-5096	CLIP-seq
MIRT1233731	hsa-miR-510	CLIP-seq
MIRT1233732	hsa-miR-512-5p	CLIP-seq
MIRT1233708	hsa-miR-575	CLIP-seq
MIRT1233733	hsa-miR-656	CLIP-seq
MIRT1552316	hsa-miR-3662	CLIP-seq
MIRT2068776	hsa-miR-106a	CLIP-seq
MIRT2068777	hsa-miR-106b	CLIP-seq
MIRT1233645	hsa-miR-1193	CLIP-seq
MIRT1233647	hsa-miR-122	CLIP-seq
MIRT2068778	hsa-miR-1224-3p	CLIP-seq
MIRT2068779	hsa-miR-1234	CLIP-seq
MIRT1233649	hsa-miR-1307	CLIP-seq
MIRT1233650	hsa-miR-130a	CLIP-seq
MIRT1233651	hsa-miR-130b	CLIP-seq
MIRT1233652	hsa-miR-142-3p	CLIP-seq
MIRT2068780	hsa-miR-150	CLIP-seq
MIRT2068781	hsa-miR-17	CLIP-seq
MIRT1233653	hsa-miR-1913	CLIP-seq
MIRT2068782	hsa-miR-192	CLIP-seq
MIRT1233655	hsa-miR-1976	CLIP-seq
MIRT2068783	hsa-miR-20a	CLIP-seq
MIRT2068784	hsa-miR-20b	CLIP-seq
MIRT2068785	hsa-miR-215	CLIP-seq
MIRT1233657	hsa-miR-2392	CLIP-seq
MIRT1233658	hsa-miR-301a	CLIP-seq
MIRT1233659	hsa-miR-301b	CLIP-seq
MIRT2068786	hsa-miR-302a	CLIP-seq
MIRT2068787	hsa-miR-302b	CLIP-seq
MIRT2068788	hsa-miR-302c	CLIP-seq
MIRT2068789	hsa-miR-302d	CLIP-seq
MIRT2068790	hsa-miR-302e	CLIP-seq
MIRT1233660	hsa-miR-3121-5p	CLIP-seq
MIRT1233662	hsa-miR-3152-3p	CLIP-seq
MIRT2068791	hsa-miR-323-3p	CLIP-seq
MIRT1233666	hsa-miR-324-3p	CLIP-seq
MIRT2068792	hsa-miR-3620	CLIP-seq
MIRT2068793	hsa-miR-3663-5p	CLIP-seq
MIRT1233668	hsa-miR-3666	CLIP-seq
MIRT2068794	hsa-miR-372	CLIP-seq
MIRT2068795	hsa-miR-373	CLIP-seq
MIRT1233670	hsa-miR-411	CLIP-seq
MIRT1233673	hsa-miR-4295	CLIP-seq
MIRT2068796	hsa-miR-4299	CLIP-seq
MIRT2068797	hsa-miR-4454	CLIP-seq
MIRT2068798	hsa-miR-4456	CLIP-seq
MIRT2068799	hsa-miR-4466	CLIP-seq
MIRT2068800	hsa-miR-4474-5p	CLIP-seq
MIRT1233678	hsa-miR-454	CLIP-seq
MIRT1233679	hsa-miR-4638-5p	CLIP-seq
MIRT1233682	hsa-miR-4662a-5p	CLIP-seq
MIRT1233683	hsa-miR-4671-3p	CLIP-seq
MIRT1233684	hsa-miR-4676-5p	CLIP-seq
MIRT1233685	hsa-miR-4695-3p	CLIP-seq
MIRT2068801	hsa-miR-4731-5p	CLIP-seq
MIRT2068802	hsa-miR-4775	CLIP-seq
MIRT1233688	hsa-miR-5096	CLIP-seq
MIRT2068803	hsa-miR-512-3p	CLIP-seq
MIRT2068804	hsa-miR-519d	CLIP-seq
MIRT2068805	hsa-miR-520a-3p	CLIP-seq
MIRT2068806	hsa-miR-520b	CLIP-seq
MIRT2068807	hsa-miR-520c-3p	CLIP-seq
MIRT2068808	hsa-miR-520d-3p	CLIP-seq
MIRT2068809	hsa-miR-520e	CLIP-seq
MIRT2068810	hsa-miR-520g	CLIP-seq
MIRT2068811	hsa-miR-520h	CLIP-seq
MIRT2068812	hsa-miR-548q	CLIP-seq
MIRT1233708	hsa-miR-575	CLIP-seq
MIRT2068813	hsa-miR-633	CLIP-seq
MIRT2068814	hsa-miR-675	CLIP-seq
MIRT2068815	hsa-miR-93	CLIP-seq
MIRT1233646	hsa-miR-1206	CLIP-seq
MIRT1233647	hsa-miR-122	CLIP-seq
MIRT1233649	hsa-miR-1307	CLIP-seq
MIRT1233653	hsa-miR-1913	CLIP-seq
MIRT1233655	hsa-miR-1976	CLIP-seq
MIRT2295849	hsa-miR-3187-3p	CLIP-seq
MIRT2295850	hsa-miR-3199	CLIP-seq
MIRT1233666	hsa-miR-324-3p	CLIP-seq
MIRT2295851	hsa-miR-3646	CLIP-seq
MIRT1233671	hsa-miR-4279	CLIP-seq
MIRT1233672	hsa-miR-4284	CLIP-seq
MIRT1233674	hsa-miR-4297	CLIP-seq
MIRT2295852	hsa-miR-4435	CLIP-seq
MIRT2295853	hsa-miR-4464	CLIP-seq
MIRT2295854	hsa-miR-4476	CLIP-seq
MIRT1233675	hsa-miR-4497	CLIP-seq
MIRT2295855	hsa-miR-4502	CLIP-seq
MIRT1233679	hsa-miR-4638-5p	CLIP-seq
MIRT1233685	hsa-miR-4695-3p	CLIP-seq
MIRT2295856	hsa-miR-4701-5p	CLIP-seq
MIRT2295857	hsa-miR-4719	CLIP-seq
MIRT2295858	hsa-miR-4722-3p	CLIP-seq
MIRT2295859	hsa-miR-4740-3p	CLIP-seq
MIRT2295860	hsa-miR-4748	CLIP-seq
MIRT2068802	hsa-miR-4775	CLIP-seq
MIRT2295861	hsa-miR-4803	CLIP-seq
MIRT2295862	hsa-miR-548s	CLIP-seq
MIRT2295863	hsa-miR-552	CLIP-seq
MIRT2295864	hsa-miR-588	CLIP-seq
MIRT2295865	hsa-miR-590-3p	CLIP-seq
MIRT2295866	hsa-miR-606	CLIP-seq
MIRT2068799	hsa-miR-4466	CLIP-seq
MIRT2068814	hsa-miR-675	CLIP-seq
MIRT2439490	hsa-miR-4699-3p	CLIP-seq
MIRT1233647	hsa-miR-122	CLIP-seq
MIRT2593891	hsa-miR-1278	CLIP-seq
MIRT1233649	hsa-miR-1307	CLIP-seq
MIRT1233656	hsa-miR-2276	CLIP-seq
MIRT1233660	hsa-miR-3121-5p	CLIP-seq
MIRT2593892	hsa-miR-3163	CLIP-seq
MIRT1233664	hsa-miR-3194-3p	CLIP-seq
MIRT1552316	hsa-miR-3662	CLIP-seq
MIRT1233721	hsa-miR-4272	CLIP-seq
MIRT1233672	hsa-miR-4284	CLIP-seq
MIRT1233674	hsa-miR-4297	CLIP-seq
MIRT1233724	hsa-miR-4328	CLIP-seq
MIRT2593893	hsa-miR-4495	CLIP-seq
MIRT1233675	hsa-miR-4497	CLIP-seq
MIRT1233679	hsa-miR-4638-5p	CLIP-seq
MIRT1233685	hsa-miR-4695-3p	CLIP-seq
MIRT2593894	hsa-miR-4714-5p	CLIP-seq
MIRT1233727	hsa-miR-4760-3p	CLIP-seq
MIRT2593895	hsa-miR-4762-5p	CLIP-seq
MIRT1233728	hsa-miR-4776-3p	CLIP-seq
MIRT2593896	hsa-miR-494	CLIP-seq
MIRT1233731	hsa-miR-510	CLIP-seq
MIRT1233732	hsa-miR-512-5p	CLIP-seq
MIRT1233647	hsa-miR-122	CLIP-seq
MIRT2593891	hsa-miR-1278	CLIP-seq
MIRT1233724	hsa-miR-4328	CLIP-seq
MIRT2593894	hsa-miR-4714-5p	CLIP-seq
MIRT2593895	hsa-miR-4762-5p	CLIP-seq
MIRT1233731	hsa-miR-510	CLIP-seq
MIRT1233732	hsa-miR-512-5p	CLIP-seq

Show/Hide all(3)

GO ID	Ontology	Definition	Evidence
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0016021	Component	Integral component of membrane	IEA
GO:0016254	Process	Preassembly of GPI anchor in ER membrane	TAS

MIM	HGNC	e!Ensembl
610276	26046	ENSG00000163964

Protein

UniProt ID

Q8TBF5

Protein name

GPI alpha-1,4-mannosyltransferase I, stabilizing subunit (Phosphatidylinositol-glycan biosynthesis class X protein) (PIG-X)

Protein function

Stabilizing subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylino

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08320	PIG-X	54 → 251	PIG-X / PBN1	Domain

Sequence

MAARVAAVRAAAWLLLGAATGLTRGPAAAFTAARSDAGIRAMCSEIILRQEVLKDGFHRD
LLIKVKFGESIEDLHTCRLLIKQDIPAGLYVDPYELASLRERNITEAVMVSENFDIEAPN
YLSKESEVLIYARRDSQCIDCFQAFLPVHCRYHRPHSEDGEASIVVNNPDLLMFCDQEFP
ILKCWAHSEVAAPCALENEDICQWNKMKYKSVYKNVILQVPVGLTVHTSLVCSVTLLITI
LCSTLILVAVFKYGHFSL

Sequence length

258

Interactions

View interactions

	KEGG		Reactome
	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis Metabolic pathways		Synthesis of glycosylphosphatidylinositol (GPI)

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Bardet-biedl syndrome	Bardet-Biedl Syndrome	rs397704728, rs397515335, rs397515337, rs267607031, rs121918327, rs587777801, rs587777802, rs121918328, rs587777803, rs549625604, rs137852837, rs137852833, rs137852835, rs267606719, rs199874059 View all (560 more)	29127258
Polydactyly	Polydactyly	rs1583729398, rs121917709, rs1583734240, rs121917714, rs397507422, rs398122899, rs587776959, rs386833752, rs1057518698, rs1060499558, rs755938967, rs1375768446, rs1309855392, rs1565601979, rs748321474 View all (3 more)	29127258
Rod-cone dystrophy	obsolete Rod-cone dystrophy	rs267606641, rs199476133, rs193302849, rs777668842, rs775518991, rs752300607, rs142759730, rs756225251, rs536742386, rs1588830568, rs778907433	29127258

Show/Hide Unknown Diseases (2)

Disease term	Disease name	References	Source
Unknown
Asthma	Asthma	29785011	ClinVar, GWAS
Eczema	Eczema		GWAS

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	27572108
Hereditary Breast and Ovarian Cancer Syndrome	Associate	27572108

PIGX (phosphatidylinositol glycan anchor biosynthesis class X)