AIRIM (AFG2 interacting ribosome maturation factor)

Gene

• Entrez ID: 54955
• Gene name: AFG2 interacting ribosome maturation factor
• Gene symbol: AIRIM
• Synonyms (NCBI Gene): C1orf109
• Chromosome: 1
• Chromosome location: 1p34.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT025066	hsa-miR-181a-5p	Microarray	17612493
MIRT046095	hsa-miR-125b-5p	CLASH	23622248
MIRT449796	hsa-miR-875-3p	PAR-CLIP	22100165
MIRT449795	hsa-miR-6128	PAR-CLIP	22100165
MIRT449794	hsa-miR-1185-5p	PAR-CLIP	22100165
MIRT449793	hsa-miR-3679-5p	PAR-CLIP	22100165
MIRT449792	hsa-miR-3605-5p	PAR-CLIP	22100165
MIRT449791	hsa-miR-5093	PAR-CLIP	22100165
MIRT449790	hsa-miR-152-5p	PAR-CLIP	22100165
MIRT449789	hsa-miR-1299	PAR-CLIP	22100165
MIRT449788	hsa-miR-516b-5p	PAR-CLIP	22100165
MIRT449787	hsa-miR-4782-5p	PAR-CLIP	22100165
MIRT449786	hsa-miR-5706	PAR-CLIP	22100165
MIRT449785	hsa-miR-3915	PAR-CLIP	22100165
MIRT449784	hsa-miR-1224-5p	PAR-CLIP	22100165
MIRT449783	hsa-miR-4689	PAR-CLIP	22100165
MIRT449782	hsa-miR-6858-5p	PAR-CLIP	22100165
MIRT441934	hsa-miR-4436b-3p	PAR-CLIP	22100165
MIRT441933	hsa-miR-4632-5p	PAR-CLIP	22100165
MIRT441932	hsa-miR-6735-5p	PAR-CLIP	22100165
MIRT441930	hsa-miR-6879-5p	PAR-CLIP	22100165
MIRT441931	hsa-miR-7843-5p	PAR-CLIP	22100165
MIRT441929	hsa-miR-1322	PAR-CLIP	22100165
MIRT441928	hsa-miR-4480	PAR-CLIP	22100165
MIRT441927	hsa-miR-1251-3p	PAR-CLIP	22100165
MIRT441926	hsa-miR-6744-5p	PAR-CLIP	22100165
MIRT441925	hsa-miR-1255a	PAR-CLIP	22100165
MIRT441924	hsa-miR-1255b-5p	PAR-CLIP	22100165
MIRT441923	hsa-miR-432-3p	PAR-CLIP	22100165
MIRT441921	hsa-miR-5004-3p	PAR-CLIP	22100165
MIRT449796	hsa-miR-875-3p	PAR-CLIP	22100165
MIRT449795	hsa-miR-6128	PAR-CLIP	22100165
MIRT449794	hsa-miR-1185-5p	PAR-CLIP	22100165
MIRT449793	hsa-miR-3679-5p	PAR-CLIP	22100165
MIRT449792	hsa-miR-3605-5p	PAR-CLIP	22100165
MIRT449791	hsa-miR-5093	PAR-CLIP	22100165
MIRT449790	hsa-miR-152-5p	PAR-CLIP	22100165
MIRT449789	hsa-miR-1299	PAR-CLIP	22100165
MIRT449788	hsa-miR-516b-5p	PAR-CLIP	22100165
MIRT449787	hsa-miR-4782-5p	PAR-CLIP	22100165
MIRT449786	hsa-miR-5706	PAR-CLIP	22100165
MIRT449785	hsa-miR-3915	PAR-CLIP	22100165
MIRT449784	hsa-miR-1224-5p	PAR-CLIP	22100165
MIRT449783	hsa-miR-4689	PAR-CLIP	22100165
MIRT449782	hsa-miR-6858-5p	PAR-CLIP	22100165
MIRT441934	hsa-miR-4436b-3p	PAR-CLIP	22100165
MIRT441933	hsa-miR-4632-5p	PAR-CLIP	22100165
MIRT441932	hsa-miR-6735-5p	PAR-CLIP	22100165
MIRT441930	hsa-miR-6879-5p	PAR-CLIP	22100165
MIRT441931	hsa-miR-7843-5p	PAR-CLIP	22100165
MIRT441929	hsa-miR-1322	PAR-CLIP	22100165
MIRT441928	hsa-miR-4480	PAR-CLIP	22100165
MIRT441927	hsa-miR-1251-3p	PAR-CLIP	22100165
MIRT441926	hsa-miR-6744-5p	PAR-CLIP	22100165
MIRT441925	hsa-miR-1255a	PAR-CLIP	22100165
MIRT441924	hsa-miR-1255b-5p	PAR-CLIP	22100165
MIRT441923	hsa-miR-432-3p	PAR-CLIP	22100165
MIRT441921	hsa-miR-5004-3p	PAR-CLIP	22100165
MIRT839273	hsa-miR-1	CLIP-seq
MIRT839274	hsa-miR-1179	CLIP-seq
MIRT839275	hsa-miR-1185	CLIP-seq
MIRT839276	hsa-miR-1224-3p	CLIP-seq
MIRT839277	hsa-miR-124	CLIP-seq
MIRT839278	hsa-miR-1256	CLIP-seq
MIRT839279	hsa-miR-1260	CLIP-seq
MIRT839280	hsa-miR-1260b	CLIP-seq
MIRT839281	hsa-miR-1269	CLIP-seq
MIRT839282	hsa-miR-1269b	CLIP-seq
MIRT839283	hsa-miR-1280	CLIP-seq
MIRT839284	hsa-miR-1285	CLIP-seq
MIRT839285	hsa-miR-1288	CLIP-seq
MIRT839286	hsa-miR-129-5p	CLIP-seq
MIRT839287	hsa-miR-150	CLIP-seq
MIRT839288	hsa-miR-1587	CLIP-seq
MIRT839289	hsa-miR-188-5p	CLIP-seq
MIRT839290	hsa-miR-2054	CLIP-seq
MIRT839291	hsa-miR-206	CLIP-seq
MIRT839292	hsa-miR-21	CLIP-seq
MIRT839293	hsa-miR-24	CLIP-seq
MIRT839294	hsa-miR-25	CLIP-seq
MIRT839295	hsa-miR-3125	CLIP-seq
MIRT839296	hsa-miR-3145-5p	CLIP-seq
MIRT839297	hsa-miR-3163	CLIP-seq
MIRT839298	hsa-miR-3187-5p	CLIP-seq
MIRT839299	hsa-miR-32	CLIP-seq
MIRT839300	hsa-miR-326	CLIP-seq
MIRT839301	hsa-miR-330-3p	CLIP-seq
MIRT839302	hsa-miR-330-5p	CLIP-seq
MIRT839303	hsa-miR-340	CLIP-seq
MIRT839304	hsa-miR-345	CLIP-seq
MIRT839305	hsa-miR-34c-3p	CLIP-seq
MIRT839306	hsa-miR-3620	CLIP-seq
MIRT839307	hsa-miR-363	CLIP-seq
MIRT839308	hsa-miR-3661	CLIP-seq
MIRT839309	hsa-miR-367	CLIP-seq
MIRT839310	hsa-miR-3671	CLIP-seq
MIRT839311	hsa-miR-3689a-3p	CLIP-seq
MIRT839312	hsa-miR-3689c	CLIP-seq
MIRT839313	hsa-miR-3714	CLIP-seq
MIRT839314	hsa-miR-376c	CLIP-seq
MIRT839315	hsa-miR-378g	CLIP-seq
MIRT839316	hsa-miR-3916	CLIP-seq
MIRT839317	hsa-miR-3922-5p	CLIP-seq
MIRT839318	hsa-miR-4257	CLIP-seq
MIRT839319	hsa-miR-4284	CLIP-seq
MIRT839320	hsa-miR-4422	CLIP-seq
MIRT839321	hsa-miR-4433	CLIP-seq
MIRT839322	hsa-miR-4459	CLIP-seq
MIRT839323	hsa-miR-4486	CLIP-seq
MIRT839324	hsa-miR-4492	CLIP-seq
MIRT839325	hsa-miR-4493	CLIP-seq
MIRT839326	hsa-miR-4498	CLIP-seq
MIRT839327	hsa-miR-4513	CLIP-seq
MIRT839328	hsa-miR-4515	CLIP-seq
MIRT839329	hsa-miR-4519	CLIP-seq
MIRT839330	hsa-miR-4522	CLIP-seq
MIRT839331	hsa-miR-4656	CLIP-seq
MIRT839332	hsa-miR-4661-3p	CLIP-seq
MIRT839333	hsa-miR-4675	CLIP-seq
MIRT839334	hsa-miR-4678	CLIP-seq
MIRT839335	hsa-miR-4698	CLIP-seq
MIRT839336	hsa-miR-4713-5p	CLIP-seq
MIRT839337	hsa-miR-4720-5p	CLIP-seq
MIRT839338	hsa-miR-4724-3p	CLIP-seq
MIRT839339	hsa-miR-4728-5p	CLIP-seq
MIRT839340	hsa-miR-4740-5p	CLIP-seq
MIRT839341	hsa-miR-4741	CLIP-seq
MIRT839342	hsa-miR-4742-3p	CLIP-seq
MIRT839343	hsa-miR-4768-3p	CLIP-seq
MIRT839344	hsa-miR-4780	CLIP-seq
MIRT839345	hsa-miR-4799-3p	CLIP-seq
MIRT839346	hsa-miR-492	CLIP-seq
MIRT839347	hsa-miR-505	CLIP-seq
MIRT839348	hsa-miR-506	CLIP-seq
MIRT839349	hsa-miR-508-5p	CLIP-seq
MIRT839350	hsa-miR-516b	CLIP-seq
MIRT839351	hsa-miR-532-3p	CLIP-seq
MIRT839352	hsa-miR-541	CLIP-seq
MIRT839353	hsa-miR-548a-5p	CLIP-seq
MIRT839354	hsa-miR-548aa	CLIP-seq
MIRT839355	hsa-miR-548ab	CLIP-seq
MIRT839356	hsa-miR-548ak	CLIP-seq
MIRT839357	hsa-miR-548b-5p	CLIP-seq
MIRT839358	hsa-miR-548c-5p	CLIP-seq
MIRT839359	hsa-miR-548d-5p	CLIP-seq
MIRT839360	hsa-miR-548h	CLIP-seq
MIRT839361	hsa-miR-548i	CLIP-seq
MIRT839362	hsa-miR-548j	CLIP-seq
MIRT839363	hsa-miR-548w	CLIP-seq
MIRT839364	hsa-miR-548y	CLIP-seq
MIRT839365	hsa-miR-556-3p	CLIP-seq
MIRT839366	hsa-miR-559	CLIP-seq
MIRT839367	hsa-miR-590-5p	CLIP-seq
MIRT839368	hsa-miR-607	CLIP-seq
MIRT839369	hsa-miR-612	CLIP-seq
MIRT839370	hsa-miR-613	CLIP-seq
MIRT839371	hsa-miR-623	CLIP-seq
MIRT839372	hsa-miR-631	CLIP-seq
MIRT839373	hsa-miR-654-5p	CLIP-seq
MIRT839374	hsa-miR-762	CLIP-seq
MIRT839375	hsa-miR-802	CLIP-seq
MIRT839376	hsa-miR-885-5p	CLIP-seq
MIRT839377	hsa-miR-922	CLIP-seq
MIRT839378	hsa-miR-92a	CLIP-seq
MIRT839379	hsa-miR-92b	CLIP-seq
MIRT1948854	hsa-miR-3942-5p	CLIP-seq
MIRT1948855	hsa-miR-4703-5p	CLIP-seq
MIRT839273	hsa-miR-1	CLIP-seq
MIRT839279	hsa-miR-1260	CLIP-seq
MIRT839280	hsa-miR-1260b	CLIP-seq
MIRT2186759	hsa-miR-181a	CLIP-seq
MIRT2186760	hsa-miR-181b	CLIP-seq
MIRT2186761	hsa-miR-181c	CLIP-seq
MIRT2186762	hsa-miR-181d	CLIP-seq
MIRT839289	hsa-miR-188-5p	CLIP-seq
MIRT839291	hsa-miR-206	CLIP-seq
MIRT2186763	hsa-miR-3122	CLIP-seq
MIRT2186764	hsa-miR-3664-3p	CLIP-seq
MIRT2186765	hsa-miR-3670	CLIP-seq
MIRT2186766	hsa-miR-3674	CLIP-seq
MIRT839311	hsa-miR-3689a-3p	CLIP-seq
MIRT839312	hsa-miR-3689c	CLIP-seq
MIRT2186767	hsa-miR-369-3p	CLIP-seq
MIRT2186768	hsa-miR-374a	CLIP-seq
MIRT2186769	hsa-miR-374b	CLIP-seq
MIRT2186770	hsa-miR-374c	CLIP-seq
MIRT2186771	hsa-miR-3913-5p	CLIP-seq
MIRT2186772	hsa-miR-3935	CLIP-seq
MIRT2186773	hsa-miR-3975	CLIP-seq
MIRT2186774	hsa-miR-4262	CLIP-seq
MIRT839332	hsa-miR-4661-3p	CLIP-seq
MIRT839337	hsa-miR-4720-5p	CLIP-seq
MIRT839339	hsa-miR-4728-5p	CLIP-seq
MIRT839344	hsa-miR-4780	CLIP-seq
MIRT839345	hsa-miR-4799-3p	CLIP-seq
MIRT839352	hsa-miR-541	CLIP-seq
MIRT839370	hsa-miR-613	CLIP-seq
MIRT839371	hsa-miR-623	CLIP-seq
MIRT839373	hsa-miR-654-5p	CLIP-seq
MIRT2186775	hsa-miR-655	CLIP-seq
MIRT839273	hsa-miR-1	CLIP-seq
MIRT2490688	hsa-miR-1202	CLIP-seq
MIRT839276	hsa-miR-1224-3p	CLIP-seq
MIRT2490689	hsa-miR-1245b-3p	CLIP-seq
MIRT839278	hsa-miR-1256	CLIP-seq
MIRT839279	hsa-miR-1260	CLIP-seq
MIRT839280	hsa-miR-1260b	CLIP-seq
MIRT839283	hsa-miR-1280	CLIP-seq
MIRT839284	hsa-miR-1285	CLIP-seq
MIRT839287	hsa-miR-150	CLIP-seq
MIRT839288	hsa-miR-1587	CLIP-seq
MIRT2490690	hsa-miR-200b	CLIP-seq
MIRT2490691	hsa-miR-200c	CLIP-seq
MIRT839291	hsa-miR-206	CLIP-seq
MIRT2490692	hsa-miR-223	CLIP-seq
MIRT2490693	hsa-miR-31	CLIP-seq
MIRT839295	hsa-miR-3125	CLIP-seq
MIRT839296	hsa-miR-3145-5p	CLIP-seq
MIRT2490694	hsa-miR-3187-3p	CLIP-seq
MIRT839298	hsa-miR-3187-5p	CLIP-seq
MIRT2490695	hsa-miR-3194-5p	CLIP-seq
MIRT839300	hsa-miR-326	CLIP-seq
MIRT839302	hsa-miR-330-5p	CLIP-seq
MIRT2490696	hsa-miR-3613-3p	CLIP-seq
MIRT2490697	hsa-miR-3622b-5p	CLIP-seq
MIRT2490698	hsa-miR-3688-5p	CLIP-seq
MIRT839315	hsa-miR-378g	CLIP-seq
MIRT2490699	hsa-miR-3910	CLIP-seq
MIRT839316	hsa-miR-3916	CLIP-seq
MIRT2490700	hsa-miR-3926	CLIP-seq
MIRT2490701	hsa-miR-3972	CLIP-seq
MIRT839318	hsa-miR-4257	CLIP-seq
MIRT2490702	hsa-miR-4282	CLIP-seq
MIRT2490703	hsa-miR-429	CLIP-seq
MIRT2490704	hsa-miR-4421	CLIP-seq
MIRT2490705	hsa-miR-4435	CLIP-seq
MIRT839323	hsa-miR-4486	CLIP-seq
MIRT839324	hsa-miR-4492	CLIP-seq
MIRT839326	hsa-miR-4498	CLIP-seq
MIRT839330	hsa-miR-4522	CLIP-seq
MIRT839331	hsa-miR-4656	CLIP-seq
MIRT839333	hsa-miR-4675	CLIP-seq
MIRT2490706	hsa-miR-4697-3p	CLIP-seq
MIRT2490707	hsa-miR-4701-5p	CLIP-seq
MIRT2490708	hsa-miR-4708-3p	CLIP-seq
MIRT839336	hsa-miR-4713-5p	CLIP-seq
MIRT839337	hsa-miR-4720-5p	CLIP-seq
MIRT839341	hsa-miR-4741	CLIP-seq
MIRT2490709	hsa-miR-4786-5p	CLIP-seq
MIRT839345	hsa-miR-4799-3p	CLIP-seq
MIRT2490710	hsa-miR-494	CLIP-seq
MIRT839349	hsa-miR-508-5p	CLIP-seq
MIRT839351	hsa-miR-532-3p	CLIP-seq
MIRT2490711	hsa-miR-548ae	CLIP-seq
MIRT2490712	hsa-miR-548aj	CLIP-seq
MIRT2490713	hsa-miR-548am	CLIP-seq
MIRT2490714	hsa-miR-548s	CLIP-seq
MIRT2490715	hsa-miR-548x	CLIP-seq
MIRT2490716	hsa-miR-588	CLIP-seq
MIRT839369	hsa-miR-612	CLIP-seq
MIRT839370	hsa-miR-613	CLIP-seq
MIRT2490717	hsa-miR-616	CLIP-seq
MIRT2490718	hsa-miR-622	CLIP-seq
MIRT2490719	hsa-miR-656	CLIP-seq
MIRT839374	hsa-miR-762	CLIP-seq
MIRT2490720	hsa-miR-769-5p	CLIP-seq
MIRT839273	hsa-miR-1	CLIP-seq
MIRT2490688	hsa-miR-1202	CLIP-seq
MIRT839276	hsa-miR-1224-3p	CLIP-seq
MIRT2490689	hsa-miR-1245b-3p	CLIP-seq
MIRT839278	hsa-miR-1256	CLIP-seq
MIRT839279	hsa-miR-1260	CLIP-seq
MIRT839280	hsa-miR-1260b	CLIP-seq
MIRT839283	hsa-miR-1280	CLIP-seq
MIRT839284	hsa-miR-1285	CLIP-seq
MIRT839287	hsa-miR-150	CLIP-seq
MIRT839288	hsa-miR-1587	CLIP-seq
MIRT2490690	hsa-miR-200b	CLIP-seq
MIRT2490691	hsa-miR-200c	CLIP-seq
MIRT839291	hsa-miR-206	CLIP-seq
MIRT2490693	hsa-miR-31	CLIP-seq
MIRT839295	hsa-miR-3125	CLIP-seq
MIRT839296	hsa-miR-3145-5p	CLIP-seq
MIRT2490694	hsa-miR-3187-3p	CLIP-seq
MIRT839298	hsa-miR-3187-5p	CLIP-seq
MIRT2490695	hsa-miR-3194-5p	CLIP-seq
MIRT839300	hsa-miR-326	CLIP-seq
MIRT839302	hsa-miR-330-5p	CLIP-seq
MIRT2490696	hsa-miR-3613-3p	CLIP-seq
MIRT2490697	hsa-miR-3622b-5p	CLIP-seq
MIRT2490698	hsa-miR-3688-5p	CLIP-seq
MIRT839315	hsa-miR-378g	CLIP-seq
MIRT2490699	hsa-miR-3910	CLIP-seq
MIRT839316	hsa-miR-3916	CLIP-seq
MIRT2490700	hsa-miR-3926	CLIP-seq
MIRT2490701	hsa-miR-3972	CLIP-seq
MIRT839318	hsa-miR-4257	CLIP-seq
MIRT2490703	hsa-miR-429	CLIP-seq
MIRT2490705	hsa-miR-4435	CLIP-seq
MIRT839323	hsa-miR-4486	CLIP-seq
MIRT839324	hsa-miR-4492	CLIP-seq
MIRT839326	hsa-miR-4498	CLIP-seq
MIRT839330	hsa-miR-4522	CLIP-seq
MIRT839331	hsa-miR-4656	CLIP-seq
MIRT839333	hsa-miR-4675	CLIP-seq
MIRT2490707	hsa-miR-4701-5p	CLIP-seq
MIRT2490708	hsa-miR-4708-3p	CLIP-seq
MIRT839336	hsa-miR-4713-5p	CLIP-seq
MIRT839337	hsa-miR-4720-5p	CLIP-seq
MIRT839341	hsa-miR-4741	CLIP-seq
MIRT839345	hsa-miR-4799-3p	CLIP-seq
MIRT2490710	hsa-miR-494	CLIP-seq
MIRT839349	hsa-miR-508-5p	CLIP-seq
MIRT839351	hsa-miR-532-3p	CLIP-seq
MIRT2490714	hsa-miR-548s	CLIP-seq
MIRT2490716	hsa-miR-588	CLIP-seq
MIRT839369	hsa-miR-612	CLIP-seq
MIRT839370	hsa-miR-613	CLIP-seq
MIRT839374	hsa-miR-762	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	21516116, 25416956, 28514442, 32296183, 33961781, 35354024, 38554706
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	22548824
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	22548824
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0042254	Process	Ribosome biogenesis	IEA
GO:0042273	Process	Ribosomal large subunit biogenesis	IDA	35354024

Other IDs

• MIM: 614799
• HGNC: 26039
• e!Ensembl: ENSG00000116922

Protein

• UniProt ID: Q9NX04
• Protein name: AFG2-interacting ribosome maturation factor (Ribosome biogenesis protein C1orf109)
• Protein function: Part of the 55LCC heterohexameric ATPase complex which is chromatin-associated and promotes replisome proteostasis to maintain replication fork progression and genome stability. Required for replication fork progression, sister chromatid cohesio
• PDB: 8RHN
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15011	CK2S	13 → 174	Casein Kinase 2 substrate	Family

• Sequence:

  MTQDRPLLAVQEALKKCFPVVEEQQGLWQSALRDCQPLLSSLSNLAEQLQAAQNLRFEDV
  PALRAFPDLKERLRRKQLVAGDIVLDKLGERLAILLKVRDMVSSHVERVFQIYEQHADTV
  GIDAVLQPSAVSPSVADMLEWLQDIERHYRKSYLKRKYLLSSIQWGDLANIQALPKAWDR
  ISKDEHQDLVQDILLNVSFFLEE

• Sequence length: 203

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Familial cancer of breast	Uncertain significance	rs148859861	RCV005932349
Melanoma	Uncertain significance	rs148859861	RCV005932350