TMEM161A (transmembrane protein 161A)

Gene

• Entrez ID: 54929
• Gene name: Transmembrane protein 161A
• Gene symbol: TMEM161A
• Synonyms (NCBI Gene): AROS-29, AROS29
• Chromosome: 19
• Chromosome location: 19p13.11

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT023011	hsa-miR-124-3p	Microarray	18668037
MIRT049308	hsa-miR-92a-3p	CLASH	23622248
MIRT042309	hsa-miR-484	CLASH	23622248
MIRT2129424	hsa-miR-1913	CLIP-seq
MIRT2129425	hsa-miR-3189-5p	CLIP-seq
MIRT2129426	hsa-miR-324-3p	CLIP-seq
MIRT2129427	hsa-miR-3657	CLIP-seq
MIRT2129428	hsa-miR-4449	CLIP-seq
MIRT2129429	hsa-miR-4758-3p	CLIP-seq
MIRT2129430	hsa-miR-873	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	28298427
GO:0016020	Component	Membrane	IEA
GO:0032526	Process	Response to retinoic acid	IDA	16551573
GO:0034599	Process	Cellular response to oxidative stress	IDA	16551573
GO:0034644	Process	Cellular response to UV	IDA	16551573
GO:0045739	Process	Positive regulation of DNA repair	IMP	16551573
GO:1902230	Process	Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	IMP	16551573

Other IDs

• MIM: 618966
• HGNC: 26020
• e!Ensembl: ENSG00000064545

Protein

• UniProt ID: Q9NX61
• Protein name: Transmembrane protein 161A (Adaptive response to oxidative stress protein 29) (AROS-29)
• Protein function: May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF10268	Tmemb_161AB	2 → 477	Predicted transmembrane protein 161AB	Family

• Sequence:

  MAVLGVQLVVTLLTATLMHRLAPHCSFARWLLCNGSLFRYKHPSEEELRALAGKPRPRGR
  KERWANGLSEEKPLSVPRDAPFQLETCPLTTVDALVLRFFLEYQWFVDFAVYSGGVYLFT
  EAYYYMLGPAKETNIAVFWCLLTVTFSIKMFLTVTRLYFSAEEGGERSVCLTFAFLFLLL
  AMLVQVVREETLELGLEPGLASMTQNLEPLLKKQGWDWALPVAKLAIRVGLAVVGSVLGA
  FLTFPGLRLAQTHRDALTMSEDRPMLQFLLHTSFLSPLFILWLWTKPIARDFLHQPPFGE
  TRFSLLSDSAFDSGRLWLLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRREAGRIEAREI
  QQRVVRVYCYVTVVSLQYLTPLILTLNCTLLLKTLGGYSWGLGPAPLLSPDPSSASAAPI
  GSGEDEVQQTAARIAGALGGLLTPLFLRGVLAYLIWWTAACQLLASLFGLYFHQHLAGS

• Sequence length: 479