Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
54929
Gene name Gene Name - the full gene name approved by the HGNC.
Transmembrane protein 161A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TMEM161A
Synonyms (NCBI Gene) Gene synonyms aliases
AROS-29, AROS29
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19p13.11
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT023011 hsa-miR-124-3p Microarray 18668037
MIRT049308 hsa-miR-92a-3p CLASH 23622248
MIRT042309 hsa-miR-484 CLASH 23622248
MIRT2129424 hsa-miR-1913 CLIP-seq
MIRT2129425 hsa-miR-3189-5p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 28298427
GO:0016020 Component Membrane IEA
GO:0032526 Process Response to retinoic acid IDA 16551573
GO:0034599 Process Cellular response to oxidative stress IDA 16551573
GO:0034644 Process Cellular response to UV IDA 16551573
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
618966 26020 ENSG00000064545
Protein
UniProt ID Q9NX61
Protein name Transmembrane protein 161A (Adaptive response to oxidative stress protein 29) (AROS-29)
Protein function May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF10268 Tmemb_161AB 2 477 Predicted transmembrane protein 161AB Family
Sequence
Sequence length 479
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Restless Legs Syndrome Restless legs syndrome N/A N/A GWAS