Gene Gene information from NCBI Gene database.
Entrez ID 54893
Gene name Myotubularin related protein 10
Gene symbol MTMR10
Synonyms (NCBI Gene)
-
Chromosome 15
Chromosome location 15q13.3
miRNA miRNA information provided by mirtarbase database.
517
miRTarBase ID miRNA Experiments Reference
MIRT019381 hsa-miR-148b-3p Microarray 17612493
MIRT021829 hsa-miR-132-3p Microarray 17612493
MIRT679020 hsa-miR-4797-5p HITS-CLIP 23824327
MIRT679019 hsa-miR-5007-5p HITS-CLIP 23824327
MIRT679018 hsa-miR-500b-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
4
GO ID Ontology Definition Evidence Reference
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IDA 16787938
GO:0005829 Component Cytosol TAS
GO:0016020 Component Membrane IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NXD2
Protein name Myotubularin-related protein 10 (Inactive phosphatidylinositol 3-phosphatase 10)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06602 Myotub-related 212 334 Myotubularin-like phosphatase domain Domain
PF06602 Myotub-related 330 512 Myotubularin-like phosphatase domain Domain
PF12578 3-PAP 574 705 Myotubularin-associated protein Family
Sequence
MFSLKPPKPTFRSYLLPPPQTDDKINSEPKIKKLEPVLLPGEIVVNEVNFVRKCIATDTS
QYDLWGKLICSNFKISFITDDPMPLQKFHYRNLLLGEHDVPLTCIEQIVTVNDHKRKQKV
LGPNQKLKFNPTELIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEY
VGKKYHNSANKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGASGWR
VCSINEGYMISTCLPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSHSNGSALVRMALI
KDVLQQRKIDQRICNAITKSHPQRSDVYK
SDLDKTLPNIQEVQAAFVKLKQLCVNEPFEE
TEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQVM
LDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKESPLFLLFLDATWQLLEQYPAA
FEFSETYLAVLYDSTRISLFGTFLFNSPHQRV
KQSTEFAISKNIQLGDEKGLKFPSVWDW
SLQFTAKDRTLFHNPFYIGKSTPCIQNGSVKSFKRTKKSYSSTLRGMPSALKNGIISDQE
LLPRRNSLILKPKPDPAQQTDSQNSDTEQYFREWFSKPANLHGVILPRVSGTHIKLWKLC
YFRWVPEAQISLGGSITAFHKLSLLADEVDVLSRMLRQQRSGPLE
ACYGELGQSRMYFNA
SGPHHTDTSGTPEFLSSSFPFSPVGNLCRRSILGTPLSKFLSGAKIWLSTETLANED
Sequence length 777
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
HUNTINGTON DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
INTERSTITIAL NEPHRITIS, KARYOMEGALIC Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations