Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	54879
Gene name	Suppression of tumorigenicity 7 like
Gene symbol	ST7L
Synonyms (NCBI Gene)	FAM4BST7RSTLR
Chromosome	1
Chromosome location	1p13.2
Summary	This gene was identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of

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miRTarBase ID	miRNA	Experiments	Reference
MIRT007215	hsa-miR-24-3p	Luciferase reporter assayqRT-PCRWestern blot	23142218
MIRT007215	hsa-miR-24-3p	Luciferase reporter assayqRT-PCRWestern blot	23142218
MIRT040824	hsa-miR-18a-3p	CLASH	23622248
MIRT488594	hsa-miR-1321	PAR-CLIP	23592263
MIRT488593	hsa-miR-4739	PAR-CLIP	23592263
MIRT488591	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT488592	hsa-miR-4270	PAR-CLIP	23592263
MIRT488590	hsa-miR-4441	PAR-CLIP	23592263
MIRT488589	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT488588	hsa-miR-7113-5p	PAR-CLIP	23592263
MIRT488587	hsa-miR-7515	PAR-CLIP	23592263
MIRT488586	hsa-miR-4731-5p	PAR-CLIP	23592263
MIRT488584	hsa-miR-7154-3p	PAR-CLIP	23592263
MIRT488585	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT488583	hsa-miR-3180	PAR-CLIP	23592263
MIRT488582	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT488581	hsa-miR-3196	PAR-CLIP	23592263
MIRT488580	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT488594	hsa-miR-1321	PAR-CLIP	23592263
MIRT488593	hsa-miR-4739	PAR-CLIP	23592263
MIRT488591	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT488592	hsa-miR-4270	PAR-CLIP	23592263
MIRT488590	hsa-miR-4441	PAR-CLIP	23592263
MIRT488589	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT488588	hsa-miR-7113-5p	PAR-CLIP	23592263
MIRT488587	hsa-miR-7515	PAR-CLIP	23592263
MIRT488586	hsa-miR-4731-5p	PAR-CLIP	23592263
MIRT488584	hsa-miR-7154-3p	PAR-CLIP	23592263
MIRT488585	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT488583	hsa-miR-3180	PAR-CLIP	23592263
MIRT488582	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT488581	hsa-miR-3196	PAR-CLIP	23592263
MIRT488580	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT1393822	hsa-miR-3123	CLIP-seq
MIRT1393823	hsa-miR-3177-5p	CLIP-seq
MIRT1393824	hsa-miR-329	CLIP-seq
MIRT1393825	hsa-miR-362-3p	CLIP-seq
MIRT1393826	hsa-miR-376c	CLIP-seq
MIRT1393827	hsa-miR-3925-5p	CLIP-seq
MIRT1393828	hsa-miR-3941	CLIP-seq
MIRT1393829	hsa-miR-3976	CLIP-seq
MIRT1393830	hsa-miR-466	CLIP-seq
MIRT1393831	hsa-miR-4672	CLIP-seq
MIRT1393832	hsa-miR-4789-3p	CLIP-seq
MIRT1393833	hsa-miR-603	CLIP-seq
MIRT1393834	hsa-miR-642b	CLIP-seq
MIRT1393835	hsa-miR-1238	CLIP-seq
MIRT1393836	hsa-miR-1290	CLIP-seq
MIRT1393837	hsa-miR-3159	CLIP-seq
MIRT1393838	hsa-miR-4264	CLIP-seq
MIRT1393839	hsa-miR-622	CLIP-seq
MIRT1393840	hsa-miR-651	CLIP-seq
MIRT1393841	hsa-miR-1273f	CLIP-seq
MIRT1393842	hsa-miR-383	CLIP-seq
MIRT1393843	hsa-miR-3919	CLIP-seq
MIRT1393844	hsa-miR-4514	CLIP-seq
MIRT1393845	hsa-miR-4692	CLIP-seq
MIRT1393846	hsa-miR-4756-3p	CLIP-seq
MIRT1393847	hsa-miR-4775	CLIP-seq
MIRT1393848	hsa-miR-578	CLIP-seq
MIRT1393849	hsa-miR-581	CLIP-seq
MIRT1393847	hsa-miR-4775	CLIP-seq
MIRT1393847	hsa-miR-4775	CLIP-seq
MIRT2634157	hsa-miR-1206	CLIP-seq
MIRT2634158	hsa-miR-1266	CLIP-seq
MIRT1393841	hsa-miR-1273f	CLIP-seq
MIRT2634159	hsa-miR-143	CLIP-seq
MIRT2634160	hsa-miR-146a	CLIP-seq
MIRT2634161	hsa-miR-146b-5p	CLIP-seq
MIRT2634162	hsa-miR-153	CLIP-seq
MIRT2634163	hsa-miR-2467-3p	CLIP-seq
MIRT2634164	hsa-miR-298	CLIP-seq
MIRT1393822	hsa-miR-3123	CLIP-seq
MIRT2634165	hsa-miR-3134	CLIP-seq
MIRT2634166	hsa-miR-3155	CLIP-seq
MIRT2634167	hsa-miR-3155b	CLIP-seq
MIRT2634168	hsa-miR-3158-5p	CLIP-seq
MIRT2634169	hsa-miR-3174	CLIP-seq
MIRT2634170	hsa-miR-331-3p	CLIP-seq
MIRT2634171	hsa-miR-3605-3p	CLIP-seq
MIRT2634172	hsa-miR-3646	CLIP-seq
MIRT2634173	hsa-miR-3664-3p	CLIP-seq
MIRT2634174	hsa-miR-3672	CLIP-seq
MIRT2634175	hsa-miR-3678-3p	CLIP-seq
MIRT1393826	hsa-miR-376c	CLIP-seq
MIRT1393827	hsa-miR-3925-5p	CLIP-seq
MIRT1393829	hsa-miR-3976	CLIP-seq
MIRT2634176	hsa-miR-4251	CLIP-seq
MIRT2634177	hsa-miR-4292	CLIP-seq
MIRT2634178	hsa-miR-4313	CLIP-seq
MIRT2634179	hsa-miR-4518	CLIP-seq
MIRT2634180	hsa-miR-4534	CLIP-seq
MIRT2634181	hsa-miR-455-5p	CLIP-seq
MIRT2634182	hsa-miR-4632	CLIP-seq
MIRT2634183	hsa-miR-4663	CLIP-seq
MIRT2634184	hsa-miR-4708-3p	CLIP-seq
MIRT2634185	hsa-miR-4708-5p	CLIP-seq
MIRT1393846	hsa-miR-4756-3p	CLIP-seq
MIRT2634186	hsa-miR-4768-5p	CLIP-seq
MIRT2634187	hsa-miR-4770	CLIP-seq
MIRT1393832	hsa-miR-4789-3p	CLIP-seq
MIRT2634188	hsa-miR-4793-5p	CLIP-seq
MIRT2634189	hsa-miR-4797-5p	CLIP-seq
MIRT2634190	hsa-miR-484	CLIP-seq
MIRT2634191	hsa-miR-568	CLIP-seq
MIRT2634192	hsa-miR-576-3p	CLIP-seq
MIRT2634193	hsa-miR-580	CLIP-seq
MIRT1393834	hsa-miR-642b	CLIP-seq
MIRT2634194	hsa-miR-767-3p	CLIP-seq
MIRT2634195	hsa-miR-921	CLIP-seq
MIRT2634196	hsa-miR-942	CLIP-seq
MIRT2634174	hsa-miR-3672	CLIP-seq
MIRT2634184	hsa-miR-4708-3p	CLIP-seq
MIRT2634191	hsa-miR-568	CLIP-seq

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GO ID	Ontology	Definition	Evidence
GO:0016020	Component	Membrane	IEA
GO:0030308	Process	Negative regulation of cell growth	IEA
GO:0030308	Process	Negative regulation of cell growth	ISS

MIM	HGNC	e!Ensembl
617640	18441	ENSG00000007341

Q8TDW4

Protein name

Suppressor of tumorigenicity 7 protein-like (ST7-related protein)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04184	ST7	38 → 555	ST7 protein	Family

Sequence

MADRGGVGEAAAVGASPASVPGLNPTLGWRERLRAGLAGTGASLWFVAGLGLLYALRIPL
RLCENLAAVTVFLNSLTPKFYVALTGTSSLISGLIFIFEWWYFHKHGTSFIEQVSVSHLQ
PLMGGTESSISEPGSPSRNRENETSRQNLSECKVWRNPLNLFRGAEYRRYTWVTGKEPLT
YYDMNLSAQDHQTFFTCDTDFLRPSDTVMQKAWRERNPPARIKAAYQALELNNDCATAYV
LLAEEEATTIVDAERLFKQALKAGETIYRQSQQCQHQSPQHEAQLRRDTNVLVYIKRRLA
MCARKLGRIREAVKIMRDLMKEFPPLTMLNIHENLLESLLELQAYPDVQAVLAKYDDISL
PKSAAICYTAALLKTRTVSEKFSPETASRRGLSTAEINAVEAIHRAVEFNPHVPKYLLEM
KSLILPPEHILKRGDSEAIAYAFFHLQHWKRIEGALNLLQCTWEGTFRMIPYPLEKGHLF
YPYPSCTETADRELLPTFHHVSVYPKKELPLFIHFTAGFCSSTAMIAILTHQFPEIMGIF
AKAVLGLWCPQPWASSGFEENTQDLKSEDLGLSSG

Sequence length

575

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OPEN-ANGLE GLAUCOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANCREATIC CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Carcinoma Ovarian Epithelial	Associate	27537390	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	27537390	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Associate	32924881	★★★★★ ★☆☆☆☆ Found in Text Mining only

ST7L (suppression of tumorigenicity 7 like)