Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	54875
Gene name	Centlein
Gene symbol	CNTLN
Synonyms (NCBI Gene)	C9orf101C9orf39bA340N12.1
Chromosome	9
Chromosome location	9p22.2

116

Show/Hide all (116)

miRTarBase ID	miRNA	Experiments	Reference
MIRT029145	hsa-miR-26b-5p	Microarray	19088304
MIRT047533	hsa-miR-10a-5p	CLASH	23622248
MIRT572615	hsa-miR-548m	PAR-CLIP	20371350
MIRT572616	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT572614	hsa-miR-545-5p	PAR-CLIP	20371350
MIRT572613	hsa-miR-222-5p	PAR-CLIP	20371350
MIRT572612	hsa-miR-8055	PAR-CLIP	20371350
MIRT572611	hsa-miR-129-5p	PAR-CLIP	20371350
MIRT572611	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT572612	hsa-miR-8055	HITS-CLIP	27418678
MIRT572615	hsa-miR-548m	PAR-CLIP	20371350
MIRT572616	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT572614	hsa-miR-545-5p	PAR-CLIP	20371350
MIRT572613	hsa-miR-222-5p	PAR-CLIP	20371350
MIRT572612	hsa-miR-8055	PAR-CLIP	20371350
MIRT572611	hsa-miR-129-5p	PAR-CLIP	20371350
MIRT901568	hsa-miR-1206	CLIP-seq
MIRT901569	hsa-miR-1272	CLIP-seq
MIRT901570	hsa-miR-1301	CLIP-seq
MIRT901571	hsa-miR-1322	CLIP-seq
MIRT901572	hsa-miR-137	CLIP-seq
MIRT901573	hsa-miR-145	CLIP-seq
MIRT901574	hsa-miR-188-3p	CLIP-seq
MIRT901575	hsa-miR-203	CLIP-seq
MIRT901576	hsa-miR-2052	CLIP-seq
MIRT901577	hsa-miR-25	CLIP-seq
MIRT901578	hsa-miR-3129-3p	CLIP-seq
MIRT901579	hsa-miR-3189-3p	CLIP-seq
MIRT901580	hsa-miR-32	CLIP-seq
MIRT901581	hsa-miR-3609	CLIP-seq
MIRT901582	hsa-miR-3611	CLIP-seq
MIRT901583	hsa-miR-363	CLIP-seq
MIRT901584	hsa-miR-3668	CLIP-seq
MIRT901585	hsa-miR-367	CLIP-seq
MIRT901586	hsa-miR-383	CLIP-seq
MIRT901587	hsa-miR-3919	CLIP-seq
MIRT901588	hsa-miR-4272	CLIP-seq
MIRT901589	hsa-miR-4290	CLIP-seq
MIRT901590	hsa-miR-4327	CLIP-seq
MIRT901591	hsa-miR-4328	CLIP-seq
MIRT901592	hsa-miR-4452	CLIP-seq
MIRT901593	hsa-miR-4660	CLIP-seq
MIRT901594	hsa-miR-4667-3p	CLIP-seq
MIRT901595	hsa-miR-4668-3p	CLIP-seq
MIRT901596	hsa-miR-4687-5p	CLIP-seq
MIRT901597	hsa-miR-4698	CLIP-seq
MIRT901598	hsa-miR-4699-5p	CLIP-seq
MIRT901599	hsa-miR-4732-5p	CLIP-seq
MIRT901600	hsa-miR-4735-5p	CLIP-seq
MIRT901601	hsa-miR-4756-3p	CLIP-seq
MIRT901602	hsa-miR-4775	CLIP-seq
MIRT901603	hsa-miR-4785	CLIP-seq
MIRT901604	hsa-miR-488	CLIP-seq
MIRT901605	hsa-miR-5047	CLIP-seq
MIRT901606	hsa-miR-545	CLIP-seq
MIRT901607	hsa-miR-548ah	CLIP-seq
MIRT901608	hsa-miR-548g	CLIP-seq
MIRT901609	hsa-miR-548n	CLIP-seq
MIRT901610	hsa-miR-548t	CLIP-seq
MIRT901611	hsa-miR-590-3p	CLIP-seq
MIRT901612	hsa-miR-758	CLIP-seq
MIRT901613	hsa-miR-92a	CLIP-seq
MIRT901614	hsa-miR-92b	CLIP-seq
MIRT901597	hsa-miR-4698	CLIP-seq
MIRT2203132	hsa-miR-4707-3p	CLIP-seq
MIRT2203133	hsa-miR-221	CLIP-seq
MIRT2203134	hsa-miR-222	CLIP-seq
MIRT2203135	hsa-miR-4704-5p	CLIP-seq
MIRT2203136	hsa-miR-548v	CLIP-seq
MIRT2386302	hsa-miR-1827	CLIP-seq
MIRT2386303	hsa-miR-299-3p	CLIP-seq
MIRT2386304	hsa-miR-3612	CLIP-seq
MIRT2386305	hsa-miR-3689a-3p	CLIP-seq
MIRT2386306	hsa-miR-3689c	CLIP-seq
MIRT2386307	hsa-miR-4269	CLIP-seq
MIRT2386308	hsa-miR-4648	CLIP-seq
MIRT2386309	hsa-miR-4654	CLIP-seq
MIRT2386310	hsa-miR-4728-5p	CLIP-seq
MIRT2386311	hsa-miR-4769-5p	CLIP-seq
MIRT2386312	hsa-miR-650	CLIP-seq
MIRT2386313	hsa-miR-940	CLIP-seq
MIRT2447404	hsa-miR-1281	CLIP-seq
MIRT2447405	hsa-miR-1297	CLIP-seq
MIRT2447406	hsa-miR-150	CLIP-seq
MIRT2447407	hsa-miR-1915	CLIP-seq
MIRT2447408	hsa-miR-1976	CLIP-seq
MIRT2447409	hsa-miR-26a	CLIP-seq
MIRT2447410	hsa-miR-26b	CLIP-seq
MIRT2447411	hsa-miR-4279	CLIP-seq
MIRT2447412	hsa-miR-4465	CLIP-seq
MIRT2447413	hsa-miR-4722-3p	CLIP-seq
MIRT2447414	hsa-miR-4726-3p	CLIP-seq
MIRT2447404	hsa-miR-1281	CLIP-seq
MIRT2447405	hsa-miR-1297	CLIP-seq
MIRT2447406	hsa-miR-150	CLIP-seq
MIRT2447407	hsa-miR-1915	CLIP-seq
MIRT2447408	hsa-miR-1976	CLIP-seq
MIRT2447409	hsa-miR-26a	CLIP-seq
MIRT2447410	hsa-miR-26b	CLIP-seq
MIRT2447411	hsa-miR-4279	CLIP-seq
MIRT2447412	hsa-miR-4465	CLIP-seq
MIRT2447413	hsa-miR-4722-3p	CLIP-seq
MIRT2447414	hsa-miR-4726-3p	CLIP-seq
MIRT2506146	hsa-miR-562	CLIP-seq
MIRT2447404	hsa-miR-1281	CLIP-seq
MIRT2447405	hsa-miR-1297	CLIP-seq
MIRT2447406	hsa-miR-150	CLIP-seq
MIRT2447407	hsa-miR-1915	CLIP-seq
MIRT2447408	hsa-miR-1976	CLIP-seq
MIRT2447409	hsa-miR-26a	CLIP-seq
MIRT2447410	hsa-miR-26b	CLIP-seq
MIRT2447411	hsa-miR-4279	CLIP-seq
MIRT2447412	hsa-miR-4465	CLIP-seq
MIRT2447413	hsa-miR-4722-3p	CLIP-seq
MIRT2447414	hsa-miR-4726-3p	CLIP-seq
MIRT2506146	hsa-miR-562	CLIP-seq

Show/Hide all (25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IDA	24554434
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IBA
GO:0005813	Component	Centrosome	IDA
GO:0005814	Component	Centriole	IBA
GO:0005814	Component	Centriole	IDA	24554434
GO:0005814	Component	Centriole	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005856	Component	Cytoskeleton	IEA
GO:0007283	Process	Spermatogenesis	IEA
GO:0007338	Process	Single fertilization	IEA
GO:0008104	Process	Intracellular protein localization	IEA
GO:0010457	Process	Centriole-centriole cohesion	IBA
GO:0010457	Process	Centriole-centriole cohesion	IMP	24554434
GO:0019901	Function	Protein kinase binding	IPI	24554434
GO:0019904	Function	Protein domain specific binding	IPI	24554434
GO:0030674	Function	Protein-macromolecule adaptor activity	IMP	24554434
GO:0032880	Process	Regulation of protein localization	IEA
GO:0033365	Process	Protein localization to organelle	IBA
GO:0033365	Process	Protein localization to organelle	IMP	24554434
GO:0065003	Process	Protein-containing complex assembly	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:0120212	Component	Sperm head-tail coupling apparatus	IEA

MIM	HGNC	e!Ensembl
611870	23432	ENSG00000044459

Q9NXG0

Protein name

Centlein (Centrosomal protein)

Protein function

Required for centrosome cohesion and recruitment of CEP68 to centrosomes.

Family and domains

Sequence

MAARSPPSPHPSPPARQLGPRSPRVGRGAEVHAMRSEASGFAGAAREVVADESDKIWVGE
EGSGGRRGPGGAAPAHAPLLSAPMGSRRLEGISVEEAMVTRTQLLEEELSSLKEELALCQ
ADKEFVWSLWKRLQVTNPDLTQVVSLVVEREKQKSEAKDRKVLEILQVKDAKIQEFEQRE
SVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVI
KNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQ
SKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQVLNM
DTQKVLRNQEDVHTAESISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQLLQKEQENA
KLKEKLQESQGAPLPLPQESDPDYSAQVPHRPSLSSLETLMVSQKSEIEYLQEKLKIANE
KLSENISANKGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQKLRKAERKIEN
LEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADP
QQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAER
REEQLFRSGEDDEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMK
ENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAE
ANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYDCKTTMTKVKFKAAKKNCSVG
RHHTVLNHSIKVMSNVFENLSKDGWEDVSESSSDSEAQTSQTLGTIIVETSQKISPTEDG
KDQKESDPTEDSQTQGKEIVQTYLNIDGKTPKDYFHDKNAKKPTFQKKNCKMQKSSHTAV
PTRVNREKYKNITAQKSSSNIILLRERIISLQQQNSVLQNAKKTAELSVKEYKEVNEKLL
HQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSSEITSLAEENSQVTFPRIQ
VTSLSPSRSMDLEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRME
RDITMKRHLIEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLN
VAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIETAASKQLQELALQSE
QVLEGAQKTLLLANEKVEEFTTFVKALAKELQNDVHVVRRQIRELKKMKKNRDACKTSTH
KAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAENDKEWMLYIQKLLEGQSLTLSPR
LKCNGAIVAHQNLRLPDSSSSASAS

Sequence length

1405

Interactions

View interactions

Show/Hide Unknown Diseases (10)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Clear cell carcinoma of kidney	Uncertain significance	rs200594824, rs267602191	RCV005929107 RCV005927207
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	rs1163343070	RCV004560196
Familial cancer of breast	Benign	rs10963108	RCV005903370
Familial pancreatic carcinoma	Benign	rs10963108	RCV005903374
Hepatocellular carcinoma	Benign	rs10963108	RCV005903371
Malignant lymphoma, large B-cell, diffuse	Benign	rs10963108	RCV005903375
Melanoma	Uncertain significance	rs200594824	RCV005929108
Nonpapillary renal cell carcinoma	Benign	rs10963108	RCV005903372
Ovarian cancer	Benign	rs10963108	RCV005903373
Uterine carcinosarcoma	Benign	rs10963108	RCV005904855

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Breast Neoplasms	Associate	25901761, 36788602
Infant Premature Diseases	Associate	36788602
Leber Congenital Amaurosis	Associate	22355252
Neoplasms	Associate	28854272
Plaque Amyloid	Associate	27743375
Premature Birth	Associate	36788602

CNTLN (centlein)