Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
54852
Gene name Gene Name - the full gene name approved by the HGNC.
Progestin and adipoQ receptor family member 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PAQR5
Synonyms (NCBI Gene) Gene synonyms aliases
MPRG
Chromosome Chromosome number
15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q23
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT052583 hsa-let-7a-5p CLASH 23622248
MIRT050543 hsa-miR-20a-5p CLASH 23622248
MIRT471616 hsa-miR-4432 HITS-CLIP 21572407
MIRT471615 hsa-miR-8087 HITS-CLIP 21572407
MIRT471614 hsa-miR-519a-3p HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005496 Function Steroid binding IEA
GO:0005515 Function Protein binding IPI 25416956, 32296183
GO:0005886 Component Plasma membrane IEA
GO:0007275 Process Multicellular organism development IEA
GO:0016021 Component Integral component of membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
607781 29645 ENSG00000137819
Protein
UniProt ID Q9NXK6
Protein name Membrane progestin receptor gamma (mPR gamma) (Membrane progesterone P4 receptor gamma) (Membrane progesterone receptor gamma) (Progesterone and adipoQ receptor family member 5) (Progestin and adipoQ receptor family member 5) (Progestin and adipoQ recepto
Protein function Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (PubMed:12601167). {ECO:0000269|PubMed:12601167, ECO:0000303
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03006 HlyIII 43 269 Haemolysin-III related Family
Tissue specificity TISSUE SPECIFICITY: Expressed in the brain, lung, kidney, colon, adrenal and lung. {ECO:0000269|PubMed:12601167, ECO:0000269|PubMed:16044242}.
Sequence
Sequence length 330
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Chemical carcinogenesis - receptor activation  
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Hypertension Hypertension GWAS
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 22350867
Endometrial Neoplasms Inhibit 32733932
Endometriosis Associate 32733932
Glioblastoma Associate 32077034
Neoplasms Associate 34572596