Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	54800
Gene name Gene Name - the full gene name approved by the HGNC.	Kelch like family member 24
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	KLHL24
Synonyms (NCBI Gene) Gene synonyms aliases	CMH29, DRE1, EBS6, EBSSH, KRIP6
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q27.1
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a ubiquitin ligase substrate receptor and is regulated by autoubiquitination. Variations in the translation initiation codon of this gene have been found, which result in an N-terminally truncated but more stable protei

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SNP ID	Visualize variation	Clinical significance	Consequence
rs886037956	A>G,T	Pathogenic	Missense variant, initiator codon variant, non coding transcript variant, 5 prime UTR variant
rs886037957	G>A,T	Pathogenic	Missense variant, initiator codon variant, non coding transcript variant, 5 prime UTR variant
rs1057515580	T>C	Pathogenic	Initiator codon variant, 5 prime UTR variant, missense variant, non coding transcript variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT017030	hsa-miR-335-5p	Microarray	18185580
MIRT022299	hsa-miR-124-3p	Microarray	18668037
MIRT025029	hsa-miR-183-5p	Sequencing	20371350
MIRT029040	hsa-miR-26b-5p	Microarray	19088304
MIRT029040	hsa-miR-26b-5p	Sequencing	20371350
MIRT030750	hsa-miR-21-5p	Microarray	18591254
MIRT720885	hsa-miR-4310	HITS-CLIP	19536157
MIRT720884	hsa-miR-7157-5p	HITS-CLIP	19536157
MIRT720883	hsa-miR-520d-5p	HITS-CLIP	19536157
MIRT720882	hsa-miR-524-5p	HITS-CLIP	19536157
MIRT720881	hsa-miR-3674	HITS-CLIP	19536157
MIRT708831	hsa-miR-548g-3p	HITS-CLIP	19536157
MIRT708830	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT708829	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT708828	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT708827	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT708826	hsa-miR-4262	HITS-CLIP	19536157
MIRT708825	hsa-miR-1305	HITS-CLIP	19536157
MIRT708831	hsa-miR-548g-3p	HITS-CLIP	19536157
MIRT708830	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT708829	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT708828	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT708827	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT708826	hsa-miR-4262	HITS-CLIP	19536157
MIRT708825	hsa-miR-1305	HITS-CLIP	19536157
MIRT306297	hsa-miR-4428	PAR-CLIP	21572407
MIRT306298	hsa-miR-6888-5p	PAR-CLIP	21572407
MIRT543531	hsa-miR-4501	PAR-CLIP	21572407
MIRT543530	hsa-miR-4670-3p	PAR-CLIP	21572407
MIRT306292	hsa-miR-190a-5p	PAR-CLIP	21572407
MIRT306294	hsa-miR-190b	PAR-CLIP	21572407
MIRT306295	hsa-miR-3611	PAR-CLIP	21572407
MIRT720885	hsa-miR-4310	HITS-CLIP	19536157
MIRT720884	hsa-miR-7157-5p	HITS-CLIP	19536157
MIRT720883	hsa-miR-520d-5p	HITS-CLIP	19536157
MIRT720882	hsa-miR-524-5p	HITS-CLIP	19536157
MIRT720881	hsa-miR-3674	HITS-CLIP	19536157
MIRT708831	hsa-miR-548g-3p	HITS-CLIP	19536157
MIRT708830	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT708829	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT708828	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT708827	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT708826	hsa-miR-4262	HITS-CLIP	19536157
MIRT708825	hsa-miR-1305	HITS-CLIP	19536157
MIRT708831	hsa-miR-548g-3p	HITS-CLIP	19536157
MIRT708830	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT708829	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT708828	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT708827	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT708826	hsa-miR-4262	HITS-CLIP	19536157
MIRT708825	hsa-miR-1305	HITS-CLIP	19536157
MIRT306297	hsa-miR-4428	PAR-CLIP	21572407
MIRT306298	hsa-miR-6888-5p	PAR-CLIP	21572407
MIRT543531	hsa-miR-4501	PAR-CLIP	21572407
MIRT543530	hsa-miR-4670-3p	PAR-CLIP	21572407
MIRT306292	hsa-miR-190a-5p	PAR-CLIP	21572407
MIRT306294	hsa-miR-190b	PAR-CLIP	21572407
MIRT306295	hsa-miR-3611	PAR-CLIP	21572407
MIRT1098051	hsa-miR-1207-3p	CLIP-seq
MIRT1098052	hsa-miR-134	CLIP-seq
MIRT1098053	hsa-miR-142-5p	CLIP-seq
MIRT1098054	hsa-miR-1827	CLIP-seq
MIRT1098055	hsa-miR-210	CLIP-seq
MIRT1098056	hsa-miR-224	CLIP-seq
MIRT1098057	hsa-miR-23a	CLIP-seq
MIRT1098058	hsa-miR-23b	CLIP-seq
MIRT1098059	hsa-miR-23c	CLIP-seq
MIRT1098060	hsa-miR-299-5p	CLIP-seq
MIRT1098061	hsa-miR-3118	CLIP-seq
MIRT1098062	hsa-miR-3120-3p	CLIP-seq
MIRT1098063	hsa-miR-3168	CLIP-seq
MIRT1098064	hsa-miR-3173-3p	CLIP-seq
MIRT1098065	hsa-miR-3183	CLIP-seq
MIRT1098066	hsa-miR-3613-3p	CLIP-seq
MIRT1098067	hsa-miR-3617	CLIP-seq
MIRT1098068	hsa-miR-3689d	CLIP-seq
MIRT1098069	hsa-miR-3921	CLIP-seq
MIRT1098070	hsa-miR-3929	CLIP-seq
MIRT1098071	hsa-miR-409-3p	CLIP-seq
MIRT1098072	hsa-miR-4263	CLIP-seq
MIRT1098073	hsa-miR-4302	CLIP-seq
MIRT1098074	hsa-miR-432	CLIP-seq
MIRT1098075	hsa-miR-4419b	CLIP-seq
MIRT1098076	hsa-miR-4423-5p	CLIP-seq
MIRT1098077	hsa-miR-4455	CLIP-seq
MIRT1098078	hsa-miR-4474-3p	CLIP-seq
MIRT1098079	hsa-miR-4478	CLIP-seq
MIRT1098080	hsa-miR-4649-3p	CLIP-seq
MIRT1098081	hsa-miR-4653-5p	CLIP-seq
MIRT1098082	hsa-miR-4684-5p	CLIP-seq
MIRT1098083	hsa-miR-4694-3p	CLIP-seq
MIRT1098084	hsa-miR-4696	CLIP-seq
MIRT1098085	hsa-miR-4723-3p	CLIP-seq
MIRT1098086	hsa-miR-4729	CLIP-seq
MIRT1098087	hsa-miR-4760-5p	CLIP-seq
MIRT1098088	hsa-miR-4780	CLIP-seq
MIRT1098089	hsa-miR-485-5p	CLIP-seq
MIRT1098090	hsa-miR-522	CLIP-seq
MIRT1098091	hsa-miR-548c-3p	CLIP-seq
MIRT1098092	hsa-miR-550b	CLIP-seq
MIRT1098093	hsa-miR-564	CLIP-seq
MIRT1098094	hsa-miR-579	CLIP-seq
MIRT1098095	hsa-miR-641	CLIP-seq
MIRT1098096	hsa-miR-644	CLIP-seq
MIRT1098097	hsa-miR-936	CLIP-seq
MIRT1550608	hsa-miR-125a-5p	CLIP-seq
MIRT1550609	hsa-miR-125b	CLIP-seq
MIRT1550610	hsa-miR-374c	CLIP-seq
MIRT1550611	hsa-miR-4319	CLIP-seq
MIRT1550612	hsa-miR-4699-3p	CLIP-seq
MIRT1550613	hsa-miR-4732-3p	CLIP-seq
MIRT1550614	hsa-miR-496	CLIP-seq
MIRT1550615	hsa-miR-499-3p	CLIP-seq
MIRT1550616	hsa-miR-499a-3p	CLIP-seq
MIRT1098091	hsa-miR-548c-3p	CLIP-seq
MIRT1550617	hsa-miR-655	CLIP-seq
MIRT1550618	hsa-miR-670	CLIP-seq
MIRT1556598	hsa-miR-3647-3p	CLIP-seq
MIRT1556599	hsa-miR-4282	CLIP-seq
MIRT1556600	hsa-miR-4496	CLIP-seq
MIRT1556601	hsa-miR-889	CLIP-seq
MIRT1922198	hsa-miR-188-5p	CLIP-seq
MIRT1922199	hsa-miR-3667-5p	CLIP-seq
MIRT1922200	hsa-miR-4457	CLIP-seq
MIRT1922201	hsa-miR-451b	CLIP-seq
MIRT1098084	hsa-miR-4696	CLIP-seq
MIRT1922202	hsa-miR-4711-5p	CLIP-seq
MIRT1922203	hsa-miR-4713-5p	CLIP-seq
MIRT1922204	hsa-miR-513b	CLIP-seq
MIRT2026655	hsa-miR-1238	CLIP-seq
MIRT2026656	hsa-miR-1303	CLIP-seq
MIRT2026657	hsa-miR-136	CLIP-seq
MIRT2026658	hsa-miR-24	CLIP-seq
MIRT1098062	hsa-miR-3120-3p	CLIP-seq
MIRT2026659	hsa-miR-3124-3p	CLIP-seq
MIRT2026660	hsa-miR-3148	CLIP-seq
MIRT2026661	hsa-miR-3613-5p	CLIP-seq
MIRT1922199	hsa-miR-3667-5p	CLIP-seq
MIRT2026662	hsa-miR-3692	CLIP-seq
MIRT2026663	hsa-miR-376c	CLIP-seq
MIRT2026664	hsa-miR-377	CLIP-seq
MIRT2026665	hsa-miR-378g	CLIP-seq
MIRT1556599	hsa-miR-4282	CLIP-seq
MIRT2026666	hsa-miR-4284	CLIP-seq
MIRT2026667	hsa-miR-4494	CLIP-seq
MIRT1922201	hsa-miR-451b	CLIP-seq
MIRT2026668	hsa-miR-4643	CLIP-seq
MIRT1098083	hsa-miR-4694-3p	CLIP-seq
MIRT1098084	hsa-miR-4696	CLIP-seq
MIRT2026669	hsa-miR-4699-5p	CLIP-seq
MIRT2026670	hsa-miR-511	CLIP-seq
MIRT2026671	hsa-miR-513a-3p	CLIP-seq
MIRT2026672	hsa-miR-514	CLIP-seq
MIRT2026673	hsa-miR-514b-3p	CLIP-seq
MIRT2026674	hsa-miR-526b	CLIP-seq
MIRT1098091	hsa-miR-548c-3p	CLIP-seq
MIRT2026675	hsa-miR-561	CLIP-seq
MIRT2026676	hsa-miR-659	CLIP-seq
MIRT1098097	hsa-miR-936	CLIP-seq
MIRT2257739	hsa-let-7a	CLIP-seq
MIRT2257740	hsa-let-7b	CLIP-seq
MIRT2257741	hsa-let-7c	CLIP-seq
MIRT2257742	hsa-let-7d	CLIP-seq
MIRT2257743	hsa-let-7e	CLIP-seq
MIRT2257744	hsa-let-7f	CLIP-seq
MIRT2257745	hsa-let-7g	CLIP-seq
MIRT2257746	hsa-let-7i	CLIP-seq
MIRT2257747	hsa-miR-101	CLIP-seq
MIRT2257748	hsa-miR-103b	CLIP-seq
MIRT2257749	hsa-miR-1183	CLIP-seq
MIRT1098051	hsa-miR-1207-3p	CLIP-seq
MIRT2257750	hsa-miR-1208	CLIP-seq
MIRT2257751	hsa-miR-1236	CLIP-seq
MIRT2257752	hsa-miR-124	CLIP-seq
MIRT2257753	hsa-miR-1244	CLIP-seq
MIRT2257754	hsa-miR-1260	CLIP-seq
MIRT2257755	hsa-miR-1260b	CLIP-seq
MIRT2257756	hsa-miR-1267	CLIP-seq
MIRT2257757	hsa-miR-1273	CLIP-seq
MIRT2257758	hsa-miR-1294	CLIP-seq
MIRT2257759	hsa-miR-129-5p	CLIP-seq
MIRT2257760	hsa-miR-1324	CLIP-seq
MIRT2257761	hsa-miR-1343	CLIP-seq
MIRT2026657	hsa-miR-136	CLIP-seq
MIRT1098053	hsa-miR-142-5p	CLIP-seq
MIRT2257762	hsa-miR-144	CLIP-seq
MIRT1098054	hsa-miR-1827	CLIP-seq
MIRT2257763	hsa-miR-183	CLIP-seq
MIRT2257764	hsa-miR-188-3p	CLIP-seq
MIRT1922198	hsa-miR-188-5p	CLIP-seq
MIRT2257765	hsa-miR-190	CLIP-seq
MIRT2257766	hsa-miR-1913	CLIP-seq
MIRT2257767	hsa-miR-1976	CLIP-seq
MIRT2257768	hsa-miR-202	CLIP-seq
MIRT2257769	hsa-miR-204	CLIP-seq
MIRT2257770	hsa-miR-211	CLIP-seq
MIRT2257771	hsa-miR-217	CLIP-seq
MIRT1098056	hsa-miR-224	CLIP-seq
MIRT2026658	hsa-miR-24	CLIP-seq
MIRT2257772	hsa-miR-3117-5p	CLIP-seq
MIRT2026659	hsa-miR-3124-3p	CLIP-seq
MIRT2257773	hsa-miR-3125	CLIP-seq
MIRT2257774	hsa-miR-3129-3p	CLIP-seq
MIRT2257775	hsa-miR-3137	CLIP-seq
MIRT2026660	hsa-miR-3148	CLIP-seq
MIRT2257776	hsa-miR-3156-3p	CLIP-seq
MIRT2257777	hsa-miR-3163	CLIP-seq
MIRT2257778	hsa-miR-3166	CLIP-seq
MIRT2257779	hsa-miR-3175	CLIP-seq
MIRT2257780	hsa-miR-3179	CLIP-seq
MIRT2257781	hsa-miR-3182	CLIP-seq
MIRT2257782	hsa-miR-3189-5p	CLIP-seq
MIRT2257783	hsa-miR-3202	CLIP-seq
MIRT2257784	hsa-miR-324-3p	CLIP-seq
MIRT2257785	hsa-miR-34b	CLIP-seq
MIRT2026661	hsa-miR-3613-5p	CLIP-seq
MIRT2257786	hsa-miR-3616-5p	CLIP-seq
MIRT2257787	hsa-miR-3647-5p	CLIP-seq
MIRT2257788	hsa-miR-3653	CLIP-seq
MIRT2257789	hsa-miR-3658	CLIP-seq
MIRT2257790	hsa-miR-3662	CLIP-seq
MIRT2257791	hsa-miR-3668	CLIP-seq
MIRT2257792	hsa-miR-3689a-3p	CLIP-seq
MIRT2257793	hsa-miR-3689c	CLIP-seq
MIRT1098068	hsa-miR-3689d	CLIP-seq
MIRT2026662	hsa-miR-3692	CLIP-seq
MIRT2257794	hsa-miR-370	CLIP-seq
MIRT2257795	hsa-miR-3714	CLIP-seq
MIRT1550610	hsa-miR-374c	CLIP-seq
MIRT2257796	hsa-miR-376a	CLIP-seq
MIRT2257797	hsa-miR-376b	CLIP-seq
MIRT2026663	hsa-miR-376c	CLIP-seq
MIRT2026664	hsa-miR-377	CLIP-seq
MIRT2026665	hsa-miR-378g	CLIP-seq
MIRT2257798	hsa-miR-3910	CLIP-seq
MIRT2257799	hsa-miR-3916	CLIP-seq
MIRT2257800	hsa-miR-3920	CLIP-seq
MIRT1098070	hsa-miR-3929	CLIP-seq
MIRT2257801	hsa-miR-3935	CLIP-seq
MIRT2257802	hsa-miR-3938	CLIP-seq
MIRT2257803	hsa-miR-409-5p	CLIP-seq
MIRT2257804	hsa-miR-4252	CLIP-seq
MIRT2257805	hsa-miR-4256	CLIP-seq
MIRT2257806	hsa-miR-4259	CLIP-seq
MIRT2257807	hsa-miR-4274	CLIP-seq
MIRT2257808	hsa-miR-4275	CLIP-seq
MIRT2257809	hsa-miR-4281	CLIP-seq
MIRT2026666	hsa-miR-4284	CLIP-seq
MIRT2257810	hsa-miR-4299	CLIP-seq
MIRT2257811	hsa-miR-4301	CLIP-seq
MIRT1098073	hsa-miR-4302	CLIP-seq
MIRT2257812	hsa-miR-4418	CLIP-seq
MIRT1098075	hsa-miR-4419b	CLIP-seq
MIRT2257813	hsa-miR-4421	CLIP-seq
MIRT2257814	hsa-miR-4425	CLIP-seq
MIRT2257815	hsa-miR-4432	CLIP-seq
MIRT2257816	hsa-miR-4436b-5p	CLIP-seq
MIRT2257817	hsa-miR-4437	CLIP-seq
MIRT1098077	hsa-miR-4455	CLIP-seq
MIRT2257818	hsa-miR-4456	CLIP-seq
MIRT2257819	hsa-miR-4458	CLIP-seq
MIRT1098078	hsa-miR-4474-3p	CLIP-seq
MIRT1098079	hsa-miR-4478	CLIP-seq
MIRT2257820	hsa-miR-4480	CLIP-seq
MIRT2257821	hsa-miR-4486	CLIP-seq
MIRT2026667	hsa-miR-4494	CLIP-seq
MIRT2257822	hsa-miR-4495	CLIP-seq
MIRT2257823	hsa-miR-4500	CLIP-seq
MIRT2257824	hsa-miR-4522	CLIP-seq
MIRT1098080	hsa-miR-4649-3p	CLIP-seq
MIRT2257825	hsa-miR-4649-5p	CLIP-seq
MIRT2257826	hsa-miR-4651	CLIP-seq
MIRT2257827	hsa-miR-4654	CLIP-seq
MIRT2257828	hsa-miR-4663	CLIP-seq
MIRT2257829	hsa-miR-4674	CLIP-seq
MIRT2257830	hsa-miR-4697-3p	CLIP-seq
MIRT2026669	hsa-miR-4699-5p	CLIP-seq
MIRT2257831	hsa-miR-4703-3p	CLIP-seq
MIRT2257832	hsa-miR-4705	CLIP-seq
MIRT2257833	hsa-miR-4710	CLIP-seq
MIRT2257834	hsa-miR-4714-3p	CLIP-seq
MIRT2257835	hsa-miR-4715-5p	CLIP-seq
MIRT2257836	hsa-miR-4718	CLIP-seq
MIRT2257837	hsa-miR-4719	CLIP-seq
MIRT2257838	hsa-miR-4722-3p	CLIP-seq
MIRT2257839	hsa-miR-4728-3p	CLIP-seq
MIRT2257840	hsa-miR-4732-5p	CLIP-seq
MIRT2257841	hsa-miR-4735-5p	CLIP-seq
MIRT2257842	hsa-miR-4747-5p	CLIP-seq
MIRT2257843	hsa-miR-4753-5p	CLIP-seq
MIRT2257844	hsa-miR-4755-5p	CLIP-seq
MIRT2257845	hsa-miR-4758-3p	CLIP-seq
MIRT2257846	hsa-miR-4762-3p	CLIP-seq
MIRT2257847	hsa-miR-4766-3p	CLIP-seq
MIRT2257848	hsa-miR-4769-5p	CLIP-seq
MIRT2257849	hsa-miR-4771	CLIP-seq
MIRT2257850	hsa-miR-4778-3p	CLIP-seq
MIRT1098088	hsa-miR-4780	CLIP-seq
MIRT2257851	hsa-miR-4789-5p	CLIP-seq
MIRT2257852	hsa-miR-4793-3p	CLIP-seq
MIRT2257853	hsa-miR-4796-3p	CLIP-seq
MIRT1098089	hsa-miR-485-5p	CLIP-seq
MIRT2257854	hsa-miR-489	CLIP-seq
MIRT2257855	hsa-miR-499a-5p	CLIP-seq
MIRT2257856	hsa-miR-506	CLIP-seq
MIRT2257857	hsa-miR-508-5p	CLIP-seq
MIRT2257858	hsa-miR-509-3-5p	CLIP-seq
MIRT2257859	hsa-miR-509-5p	CLIP-seq
MIRT2257860	hsa-miR-5096	CLIP-seq
MIRT2026670	hsa-miR-511	CLIP-seq
MIRT2026672	hsa-miR-514	CLIP-seq
MIRT2026673	hsa-miR-514b-3p	CLIP-seq
MIRT2257861	hsa-miR-516b	CLIP-seq
MIRT2257862	hsa-miR-548a-5p	CLIP-seq
MIRT2257863	hsa-miR-548ab	CLIP-seq
MIRT2257864	hsa-miR-548ac	CLIP-seq
MIRT2257865	hsa-miR-548ak	CLIP-seq
MIRT2257866	hsa-miR-548b-5p	CLIP-seq
MIRT2257867	hsa-miR-548c-5p	CLIP-seq
MIRT2257868	hsa-miR-548d-3p	CLIP-seq
MIRT2257869	hsa-miR-548d-5p	CLIP-seq
MIRT2257870	hsa-miR-548h	CLIP-seq
MIRT2257871	hsa-miR-548i	CLIP-seq
MIRT2257872	hsa-miR-548j	CLIP-seq
MIRT2257873	hsa-miR-548m	CLIP-seq
MIRT2257874	hsa-miR-548n	CLIP-seq
MIRT2257875	hsa-miR-548p	CLIP-seq
MIRT2257876	hsa-miR-548q	CLIP-seq
MIRT2257877	hsa-miR-548w	CLIP-seq
MIRT2257878	hsa-miR-548y	CLIP-seq
MIRT2257879	hsa-miR-548z	CLIP-seq
MIRT2257880	hsa-miR-559	CLIP-seq
MIRT2257881	hsa-miR-563	CLIP-seq
MIRT1098093	hsa-miR-564	CLIP-seq
MIRT2257882	hsa-miR-573	CLIP-seq
MIRT2257883	hsa-miR-576-3p	CLIP-seq
MIRT1098094	hsa-miR-579	CLIP-seq
MIRT2257884	hsa-miR-582-5p	CLIP-seq
MIRT2257885	hsa-miR-590-3p	CLIP-seq
MIRT2257886	hsa-miR-596	CLIP-seq
MIRT2257887	hsa-miR-608	CLIP-seq
MIRT2257888	hsa-miR-622	CLIP-seq
MIRT2257889	hsa-miR-623	CLIP-seq
MIRT2257890	hsa-miR-629	CLIP-seq
MIRT1098096	hsa-miR-644	CLIP-seq
MIRT1550617	hsa-miR-655	CLIP-seq
MIRT2257891	hsa-miR-656	CLIP-seq
MIRT2026676	hsa-miR-659	CLIP-seq
MIRT2257892	hsa-miR-661	CLIP-seq
MIRT2257893	hsa-miR-766	CLIP-seq
MIRT2257894	hsa-miR-802	CLIP-seq
MIRT2257895	hsa-miR-877	CLIP-seq
MIRT2257896	hsa-miR-890	CLIP-seq
MIRT1098097	hsa-miR-936	CLIP-seq
MIRT2257897	hsa-miR-98	CLIP-seq
MIRT2389955	hsa-miR-21	CLIP-seq
MIRT2389956	hsa-miR-3145-3p	CLIP-seq
MIRT2257790	hsa-miR-3662	CLIP-seq
MIRT2389957	hsa-miR-539	CLIP-seq
MIRT2389958	hsa-miR-570	CLIP-seq
MIRT2389959	hsa-miR-590-5p	CLIP-seq
MIRT2452662	hsa-miR-29a	CLIP-seq
MIRT2452663	hsa-miR-29b	CLIP-seq
MIRT2452664	hsa-miR-29c	CLIP-seq
MIRT2452665	hsa-miR-330-3p	CLIP-seq
MIRT1098066	hsa-miR-3613-3p	CLIP-seq
MIRT1098077	hsa-miR-4455	CLIP-seq
MIRT1098082	hsa-miR-4684-5p	CLIP-seq
MIRT1098091	hsa-miR-548c-3p	CLIP-seq
MIRT1098093	hsa-miR-564	CLIP-seq
MIRT2452666	hsa-miR-767-5p	CLIP-seq
MIRT2257749	hsa-miR-1183	CLIP-seq
MIRT2558841	hsa-miR-1206	CLIP-seq
MIRT2257754	hsa-miR-1260	CLIP-seq
MIRT2257755	hsa-miR-1260b	CLIP-seq
MIRT2257756	hsa-miR-1267	CLIP-seq
MIRT2026657	hsa-miR-136	CLIP-seq
MIRT1098053	hsa-miR-142-5p	CLIP-seq
MIRT2257764	hsa-miR-188-3p	CLIP-seq
MIRT1922198	hsa-miR-188-5p	CLIP-seq
MIRT2257765	hsa-miR-190	CLIP-seq
MIRT2558842	hsa-miR-1912	CLIP-seq
MIRT2558843	hsa-miR-214	CLIP-seq
MIRT1098057	hsa-miR-23a	CLIP-seq
MIRT1098058	hsa-miR-23b	CLIP-seq
MIRT1098059	hsa-miR-23c	CLIP-seq
MIRT2257772	hsa-miR-3117-5p	CLIP-seq
MIRT1098062	hsa-miR-3120-3p	CLIP-seq
MIRT2558844	hsa-miR-3120-5p	CLIP-seq
MIRT2257773	hsa-miR-3125	CLIP-seq
MIRT2257774	hsa-miR-3129-3p	CLIP-seq
MIRT2026660	hsa-miR-3148	CLIP-seq
MIRT2257776	hsa-miR-3156-3p	CLIP-seq
MIRT1098063	hsa-miR-3168	CLIP-seq
MIRT2558845	hsa-miR-339-5p	CLIP-seq
MIRT2558846	hsa-miR-340	CLIP-seq
MIRT1098066	hsa-miR-3613-3p	CLIP-seq
MIRT2026661	hsa-miR-3613-5p	CLIP-seq
MIRT2558847	hsa-miR-3619-5p	CLIP-seq
MIRT2558848	hsa-miR-3622b-5p	CLIP-seq
MIRT2558849	hsa-miR-365	CLIP-seq
MIRT2257790	hsa-miR-3662	CLIP-seq
MIRT2558850	hsa-miR-3685	CLIP-seq
MIRT2026663	hsa-miR-376c	CLIP-seq
MIRT2558851	hsa-miR-384	CLIP-seq
MIRT2257799	hsa-miR-3916	CLIP-seq
MIRT1098071	hsa-miR-409-3p	CLIP-seq
MIRT2257803	hsa-miR-409-5p	CLIP-seq
MIRT2257807	hsa-miR-4274	CLIP-seq
MIRT2257811	hsa-miR-4301	CLIP-seq
MIRT1098074	hsa-miR-432	CLIP-seq
MIRT1098077	hsa-miR-4455	CLIP-seq
MIRT2026667	hsa-miR-4494	CLIP-seq
MIRT2558852	hsa-miR-4642	CLIP-seq
MIRT1098082	hsa-miR-4684-5p	CLIP-seq
MIRT2558853	hsa-miR-4688	CLIP-seq
MIRT2558854	hsa-miR-4690-5p	CLIP-seq
MIRT1922202	hsa-miR-4711-5p	CLIP-seq
MIRT2257837	hsa-miR-4719	CLIP-seq
MIRT2257840	hsa-miR-4732-5p	CLIP-seq
MIRT2558855	hsa-miR-4760-3p	CLIP-seq
MIRT2558856	hsa-miR-4773	CLIP-seq
MIRT2558857	hsa-miR-4777-5p	CLIP-seq
MIRT2558858	hsa-miR-4800-3p	CLIP-seq
MIRT2257855	hsa-miR-499a-5p	CLIP-seq
MIRT2257860	hsa-miR-5096	CLIP-seq
MIRT2026671	hsa-miR-513a-3p	CLIP-seq
MIRT1922204	hsa-miR-513b	CLIP-seq
MIRT2558859	hsa-miR-518d-5p	CLIP-seq
MIRT2558860	hsa-miR-519b-5p	CLIP-seq
MIRT2558861	hsa-miR-519c-5p	CLIP-seq
MIRT2558862	hsa-miR-520c-5p	CLIP-seq
MIRT2558863	hsa-miR-526a	CLIP-seq
MIRT2558864	hsa-miR-548aa	CLIP-seq
MIRT1098091	hsa-miR-548c-3p	CLIP-seq
MIRT2257873	hsa-miR-548m	CLIP-seq
MIRT2026675	hsa-miR-561	CLIP-seq
MIRT1098093	hsa-miR-564	CLIP-seq
MIRT2558865	hsa-miR-580	CLIP-seq
MIRT2558866	hsa-miR-600	CLIP-seq
MIRT2257888	hsa-miR-622	CLIP-seq
MIRT2558867	hsa-miR-626	CLIP-seq
MIRT2558868	hsa-miR-761	CLIP-seq
MIRT2257895	hsa-miR-877	CLIP-seq
MIRT2257896	hsa-miR-890	CLIP-seq
MIRT2257757	hsa-miR-1273	CLIP-seq
MIRT2026657	hsa-miR-136	CLIP-seq
MIRT1098053	hsa-miR-142-5p	CLIP-seq
MIRT1922198	hsa-miR-188-5p	CLIP-seq
MIRT2257765	hsa-miR-190	CLIP-seq
MIRT2558842	hsa-miR-1912	CLIP-seq
MIRT2558843	hsa-miR-214	CLIP-seq
MIRT1098057	hsa-miR-23a	CLIP-seq
MIRT1098058	hsa-miR-23b	CLIP-seq
MIRT1098059	hsa-miR-23c	CLIP-seq
MIRT2683577	hsa-miR-28-3p	CLIP-seq
MIRT2257772	hsa-miR-3117-5p	CLIP-seq
MIRT1098062	hsa-miR-3120-3p	CLIP-seq
MIRT2558844	hsa-miR-3120-5p	CLIP-seq
MIRT2683578	hsa-miR-3122	CLIP-seq
MIRT2257773	hsa-miR-3125	CLIP-seq
MIRT2026660	hsa-miR-3148	CLIP-seq
MIRT1098063	hsa-miR-3168	CLIP-seq
MIRT2558845	hsa-miR-339-5p	CLIP-seq
MIRT2558846	hsa-miR-340	CLIP-seq
MIRT2257785	hsa-miR-34b	CLIP-seq
MIRT1098066	hsa-miR-3613-3p	CLIP-seq
MIRT2026661	hsa-miR-3613-5p	CLIP-seq
MIRT2558847	hsa-miR-3619-5p	CLIP-seq
MIRT2558848	hsa-miR-3622b-5p	CLIP-seq
MIRT2558849	hsa-miR-365	CLIP-seq
MIRT2257790	hsa-miR-3662	CLIP-seq
MIRT1922199	hsa-miR-3667-5p	CLIP-seq
MIRT2558850	hsa-miR-3685	CLIP-seq
MIRT2257792	hsa-miR-3689a-3p	CLIP-seq
MIRT2257793	hsa-miR-3689c	CLIP-seq
MIRT2026663	hsa-miR-376c	CLIP-seq
MIRT2683579	hsa-miR-382	CLIP-seq
MIRT2558851	hsa-miR-384	CLIP-seq
MIRT2683580	hsa-miR-3913-5p	CLIP-seq
MIRT2257799	hsa-miR-3916	CLIP-seq
MIRT1098071	hsa-miR-409-3p	CLIP-seq
MIRT2257803	hsa-miR-409-5p	CLIP-seq
MIRT2257804	hsa-miR-4252	CLIP-seq
MIRT2683581	hsa-miR-431	CLIP-seq
MIRT1098076	hsa-miR-4423-5p	CLIP-seq
MIRT1098077	hsa-miR-4455	CLIP-seq
MIRT1922200	hsa-miR-4457	CLIP-seq
MIRT2257821	hsa-miR-4486	CLIP-seq
MIRT1922201	hsa-miR-451b	CLIP-seq
MIRT2558852	hsa-miR-4642	CLIP-seq
MIRT2257825	hsa-miR-4649-5p	CLIP-seq
MIRT1098082	hsa-miR-4684-5p	CLIP-seq
MIRT2558854	hsa-miR-4690-5p	CLIP-seq
MIRT1098084	hsa-miR-4696	CLIP-seq
MIRT1922202	hsa-miR-4711-5p	CLIP-seq
MIRT2257837	hsa-miR-4719	CLIP-seq
MIRT2257839	hsa-miR-4728-3p	CLIP-seq
MIRT2683582	hsa-miR-4728-5p	CLIP-seq
MIRT2257840	hsa-miR-4732-5p	CLIP-seq
MIRT2558855	hsa-miR-4760-3p	CLIP-seq
MIRT2558856	hsa-miR-4773	CLIP-seq
MIRT2558857	hsa-miR-4777-5p	CLIP-seq
MIRT2257852	hsa-miR-4793-3p	CLIP-seq
MIRT2558858	hsa-miR-4800-3p	CLIP-seq
MIRT2257857	hsa-miR-508-5p	CLIP-seq
MIRT2257860	hsa-miR-5096	CLIP-seq
MIRT2026670	hsa-miR-511	CLIP-seq
MIRT1922204	hsa-miR-513b	CLIP-seq
MIRT2558859	hsa-miR-518d-5p	CLIP-seq
MIRT2558860	hsa-miR-519b-5p	CLIP-seq
MIRT2558861	hsa-miR-519c-5p	CLIP-seq
MIRT2558862	hsa-miR-520c-5p	CLIP-seq
MIRT2558863	hsa-miR-526a	CLIP-seq
MIRT2026674	hsa-miR-526b	CLIP-seq
MIRT2683583	hsa-miR-541	CLIP-seq
MIRT2558864	hsa-miR-548aa	CLIP-seq
MIRT1098091	hsa-miR-548c-3p	CLIP-seq
MIRT2257873	hsa-miR-548m	CLIP-seq
MIRT2026675	hsa-miR-561	CLIP-seq
MIRT1098093	hsa-miR-564	CLIP-seq
MIRT2558865	hsa-miR-580	CLIP-seq
MIRT2558866	hsa-miR-600	CLIP-seq
MIRT2558867	hsa-miR-626	CLIP-seq
MIRT2683584	hsa-miR-654-5p	CLIP-seq
MIRT2257892	hsa-miR-661	CLIP-seq
MIRT2558868	hsa-miR-761	CLIP-seq
MIRT2257893	hsa-miR-766	CLIP-seq
MIRT2257895	hsa-miR-877	CLIP-seq
MIRT2257896	hsa-miR-890	CLIP-seq

Show/Hide all(19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	27798626, 30190310, 32296183, 33961781
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	27889062
GO:0005737	Component	Cytoplasm	IEA
GO:0005912	Component	Adherens junction	IDA	27889062
GO:0005912	Component	Adherens junction	IEA
GO:0016567	Process	Protein ubiquitination	IDA	27798626
GO:0030057	Component	Desmosome	IDA	27889062
GO:0030057	Component	Desmosome	IEA
GO:0030424	Component	Axon	IEA
GO:0031463	Component	Cul3-RING ubiquitin ligase complex	IBA
GO:0031463	Component	Cul3-RING ubiquitin ligase complex	IMP	27798626
GO:0042995	Component	Cell projection	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:0043204	Component	Perikaryon	IEA
GO:0045109	Process	Intermediate filament organization	IMP	27889062
GO:0051865	Process	Protein autoubiquitination	IMP	27798626
GO:0070161	Component	Anchoring junction	IEA
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IBA

MIM	HGNC	e!Ensembl
611295	25947	ENSG00000114796

Protein

UniProt ID

Q6TFL4

Protein name

Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6) (Protein DRE1)

Protein function

Necessary to maintain the balance between intermediate filament stability and degradation, a process that is essential for skin integrity (PubMed:27889062). As part of the BCR(KLHL24) E3 ubiquitin ligase complex, mediates ubiquitination of KRT14

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00651	BTB	56 → 163	BTB/POZ domain	Domain
PF07707	BACK	168 → 270	BTB And C-terminal Kelch	Domain
PF01344	Kelch_1	307 → 349	Kelch motif	Repeat
PF01344	Kelch_1	353 → 394	Kelch motif	Repeat
PF01344	Kelch_1	397 → 441	Kelch motif	Repeat
PF01344	Kelch_1	443 → 483	Kelch motif	Repeat
PF01344	Kelch_1	535 → 571	Kelch motif	Repeat

Tissue specificity

TISSUE SPECIFICITY: Expressed in the skin (PubMed:27798626, PubMed:27889062). Found in keratinocytes, dermal fibroblasts, and melanocytes (PubMed:27889062). Basal-layer keratinocytes have lower KLHL24 expression than suprabasal keratinocytes (PubMed:27798

Sequence

MVLILGRRLNREDLGVRDSPATKRKVFEMDPKSLTGHEFFDFSSGSSHAENILQIFNEFR
DSRLFTDVIICVEGKEFPCHRAVLSACSSYFRAMFCNDHRESREMLVEINGILAEAMECF
LQYVYTGKVKITTENVQYLFETSSLFQISVLRDACAKFLEEQLDPCNCLGIQRFADTHSL
KTLFTKCKNFALQTFEDVSQHEEFLELDKDELIDYICSDELVIGKEEMVFEAVMRWVYRA
VDLRRPLLHELLTHVRLPLLHPNYFVQTVEVDQLIQNSPECYQLLHEARRYHILGNEMMS
PRTRPRRSTGYSEVIVVVGGCERVGGFNLPYTECYDPVTGEWKSLAKLPEFTKSEYAVCA
LRNDILVSGGRINSRDVWIYNSQLNIWIRVASLNKGRWRHKMAVLLGKVYVVGGYDGQNR
LSSVECYDSFSNRWTEVAPLKEAVSSPAVTSCVGKLFVIGGGPDDNTCSDKVQSYDPETN
SWLLRAAIPIAKRCITAVSLNNLIYVAGGLTKAIYCYDPVEDYWMHVQNTFSRQENCGMS
VCNGKIYILGGRRENGEATDTILCYDPATSIITGVAAMPRPVSYHGCVTIHRYNEKCFKL

Sequence length

600

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Epidermolysis Bullosa Simplex	Epidermolysis bullosa simplex, Koebner type, Epidermolysis bullosa simplex 6, generalized, with scarring and hair loss	rs886037957, rs886037956, rs1057515580	N/A

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Cardiomyopathy	cardiomyopathy, familial hypertrophic, 29, with polyglucosan bodies	N/A	N/A	GenCC
Hypertension	Hypertension	N/A	N/A	GWAS
Hypertrophic cardiomyopathy	hypertrophic cardiomyopathy	N/A	N/A	GenCC

Show/Hide Text Mining Associations (10)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Breast Neoplasms	Associate	34990474
Cardiomyopathies	Associate	34740256, 36672924
Cardiomyopathy Dilated	Associate	30579426, 35975634, 36672924
Cardiomyopathy Hypertrophic	Associate	36672924, 39971408
Ectodermal Dysplasia Skin Fragility Syndrome	Associate	27889062, 30579426, 34740256
Epidermolysis Bullosa Simplex	Associate	30579426, 34740256, 35975634, 39317060
Heredodegenerative Disorders Nervous System	Associate	30579426
Leukemia Myeloid Acute	Associate	32783661
Myopathy desmin storage	Associate	27889062
Skin Abnormalities	Associate	34740256

KLHL24 (kelch like family member 24)