Gene Gene information from NCBI Gene database.
Entrez ID 5480
Gene name Peptidylprolyl isomerase C
Gene symbol PPIC
Synonyms (NCBI Gene)
CYPC
Chromosome 5
Chromosome location 5q23.2
Summary The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to othe
miRNA miRNA information provided by mirtarbase database.
1073
miRTarBase ID miRNA Experiments Reference
MIRT030019 hsa-miR-26b-5p Microarray 19088304
MIRT608424 hsa-miR-8485 HITS-CLIP 19536157
MIRT608423 hsa-miR-329-3p HITS-CLIP 19536157
MIRT608422 hsa-miR-362-3p HITS-CLIP 19536157
MIRT608420 hsa-miR-6801-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
GO ID Ontology Definition Evidence Reference
GO:0003755 Function Peptidyl-prolyl cis-trans isomerase activity IBA
GO:0003755 Function Peptidyl-prolyl cis-trans isomerase activity IDA 20676357
GO:0003755 Function Peptidyl-prolyl cis-trans isomerase activity IEA
GO:0005515 Function Protein binding IPI 25416956, 32296183
GO:0005737 Component Cytoplasm IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
123842 9256 ENSG00000168938
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P45877
Protein name Peptidyl-prolyl cis-trans isomerase C (PPIase C) (EC 5.2.1.8) (Cyclophilin C) (Rotamase C)
Protein function PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.
PDB 2ESL
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00160 Pro_isomerase 41 198 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in kidney, skeletal muscle, pancreas, heart, lung, liver and to a lower extent in brain. {ECO:0000269|PubMed:8031755}.
Sequence
Sequence length 212
Interactions View interactions