PPIA (peptidylprolyl isomerase A)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5478 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Peptidylprolyl isomerase A |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PPIA |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CYPA, CYPH, HEL-S-69p |
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Chromosome
Chromosome number
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7 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7p13 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclospor |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P62937 | ||||||||||
| Protein name | Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed] | ||||||||||
| Protein function | Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:2001362, PubMed:20676357, PubMed:21245143, PubMed:21593166, PubMed:25678563). Exerts a strong chemotactic effect on leukocytes partly through activati | ||||||||||
| PDB | 1AK4 , 1AWQ , 1AWR , 1AWS , 1AWT , 1AWU , 1AWV , 1BCK , 1CWA , 1CWB , 1CWC , 1CWF , 1CWH , 1CWI , 1CWJ , 1CWK , 1CWL , 1CWM , 1CWO , 1FGL , 1M63 , 1M9C , 1M9D , 1M9E , 1M9F , 1M9X , 1M9Y , 1MF8 , 1MIK , 1NMK , 1OCA , 1RMH , 1VBS , 1VBT , 1W8L , 1W8M , 1W8V , 1YND , 1ZKF , 2ALF , 2CPL , 2CYH , 2MS4 , 2MZU , 2N0T , 2RMA , 2RMB , 2X25 , 2X2A , 2X2C , 2X2D | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 165 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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