Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	54742
Gene name Gene Name - the full gene name approved by the HGNC.	Lymphocyte antigen 6 family member K
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LY6K
Synonyms (NCBI Gene) Gene synonyms aliases	CT97, HSJ001348, URLC10, ly-6K
Chromosome Chromosome number	8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	8q24.3

Show/Hide all(107)

miRTarBase ID	miRNA	Experiments	Reference
MIRT001541	hsa-miR-155-5p	pSILAC	18668040
MIRT001541	hsa-miR-155-5p	Proteomics;Other	18668040
MIRT031622	hsa-miR-16-5p	Proteomics	18668040
MIRT720692	hsa-miR-5683	HITS-CLIP	19536157
MIRT720691	hsa-miR-6783-5p	HITS-CLIP	19536157
MIRT720690	hsa-miR-329-5p	HITS-CLIP	19536157
MIRT720689	hsa-miR-1245b-3p	HITS-CLIP	19536157
MIRT720688	hsa-miR-6798-5p	HITS-CLIP	19536157
MIRT720687	hsa-miR-3127-5p	HITS-CLIP	19536157
MIRT720686	hsa-miR-30a-3p	HITS-CLIP	19536157
MIRT720685	hsa-miR-30d-3p	HITS-CLIP	19536157
MIRT720684	hsa-miR-30e-3p	HITS-CLIP	19536157
MIRT568775	hsa-miR-382-3p	PAR-CLIP	20371350
MIRT568774	hsa-miR-892c-5p	PAR-CLIP	20371350
MIRT568772	hsa-miR-4494	PAR-CLIP	20371350
MIRT568773	hsa-miR-499b-5p	PAR-CLIP	20371350
MIRT568771	hsa-miR-412-3p	PAR-CLIP	20371350
MIRT568770	hsa-miR-6754-3p	PAR-CLIP	20371350
MIRT568769	hsa-miR-6837-3p	PAR-CLIP	20371350
MIRT568768	hsa-miR-6740-3p	PAR-CLIP	20371350
MIRT568767	hsa-miR-6802-3p	PAR-CLIP	20371350
MIRT568776	hsa-miR-6757-5p	PAR-CLIP	20371350
MIRT568775	hsa-miR-382-3p	PAR-CLIP	20371350
MIRT568774	hsa-miR-892c-5p	PAR-CLIP	20371350
MIRT568772	hsa-miR-4494	PAR-CLIP	20371350
MIRT568773	hsa-miR-499b-5p	PAR-CLIP	20371350
MIRT568771	hsa-miR-412-3p	PAR-CLIP	20371350
MIRT568770	hsa-miR-6754-3p	PAR-CLIP	20371350
MIRT568769	hsa-miR-6837-3p	PAR-CLIP	20371350
MIRT568768	hsa-miR-6740-3p	PAR-CLIP	20371350
MIRT568767	hsa-miR-6802-3p	PAR-CLIP	20371350
MIRT512431	hsa-miR-5088-3p	PAR-CLIP	23446348
MIRT512430	hsa-miR-370-3p	PAR-CLIP	23446348
MIRT512429	hsa-miR-6893-3p	PAR-CLIP	23446348
MIRT512428	hsa-miR-1976	PAR-CLIP	23446348
MIRT512427	hsa-miR-4268	PAR-CLIP	23446348
MIRT512425	hsa-miR-4448	PAR-CLIP	23446348
MIRT512426	hsa-miR-515-5p	PAR-CLIP	23446348
MIRT512424	hsa-miR-519e-5p	PAR-CLIP	23446348
MIRT512423	hsa-miR-6772-3p	PAR-CLIP	23446348
MIRT720692	hsa-miR-5683	HITS-CLIP	19536157
MIRT720691	hsa-miR-6783-5p	HITS-CLIP	19536157
MIRT720690	hsa-miR-329-5p	HITS-CLIP	19536157
MIRT720689	hsa-miR-1245b-3p	HITS-CLIP	19536157
MIRT720688	hsa-miR-6798-5p	HITS-CLIP	19536157
MIRT720687	hsa-miR-3127-5p	HITS-CLIP	19536157
MIRT720686	hsa-miR-30a-3p	HITS-CLIP	19536157
MIRT720685	hsa-miR-30d-3p	HITS-CLIP	19536157
MIRT720684	hsa-miR-30e-3p	HITS-CLIP	19536157
MIRT568775	hsa-miR-382-3p	PAR-CLIP	20371350
MIRT568774	hsa-miR-892c-5p	PAR-CLIP	20371350
MIRT568772	hsa-miR-4494	PAR-CLIP	20371350
MIRT568773	hsa-miR-499b-5p	PAR-CLIP	20371350
MIRT568771	hsa-miR-412-3p	PAR-CLIP	20371350
MIRT568770	hsa-miR-6754-3p	PAR-CLIP	20371350
MIRT568769	hsa-miR-6837-3p	PAR-CLIP	20371350
MIRT568768	hsa-miR-6740-3p	PAR-CLIP	20371350
MIRT568767	hsa-miR-6802-3p	PAR-CLIP	20371350
MIRT568776	hsa-miR-6757-5p	PAR-CLIP	20371350
MIRT568775	hsa-miR-382-3p	PAR-CLIP	20371350
MIRT568774	hsa-miR-892c-5p	PAR-CLIP	20371350
MIRT568772	hsa-miR-4494	PAR-CLIP	20371350
MIRT568773	hsa-miR-499b-5p	PAR-CLIP	20371350
MIRT568771	hsa-miR-412-3p	PAR-CLIP	20371350
MIRT568770	hsa-miR-6754-3p	PAR-CLIP	20371350
MIRT568769	hsa-miR-6837-3p	PAR-CLIP	20371350
MIRT568768	hsa-miR-6740-3p	PAR-CLIP	20371350
MIRT568767	hsa-miR-6802-3p	PAR-CLIP	20371350
MIRT512431	hsa-miR-5088-3p	PAR-CLIP	23446348
MIRT512430	hsa-miR-370-3p	PAR-CLIP	23446348
MIRT512429	hsa-miR-6893-3p	PAR-CLIP	23446348
MIRT512428	hsa-miR-1976	PAR-CLIP	23446348
MIRT512427	hsa-miR-4268	PAR-CLIP	23446348
MIRT512425	hsa-miR-4448	PAR-CLIP	23446348
MIRT512426	hsa-miR-515-5p	PAR-CLIP	23446348
MIRT512424	hsa-miR-519e-5p	PAR-CLIP	23446348
MIRT512423	hsa-miR-6772-3p	PAR-CLIP	23446348
MIRT1122894	hsa-miR-1224-5p	CLIP-seq
MIRT1122895	hsa-miR-3915	CLIP-seq
MIRT1122896	hsa-miR-3928	CLIP-seq
MIRT1122897	hsa-miR-3942-3p	CLIP-seq
MIRT1122898	hsa-miR-4490	CLIP-seq
MIRT1122899	hsa-miR-4496	CLIP-seq
MIRT1122900	hsa-miR-4689	CLIP-seq
MIRT1122901	hsa-miR-4774-5p	CLIP-seq
MIRT1122902	hsa-miR-653	CLIP-seq
MIRT1122903	hsa-miR-34b	CLIP-seq
MIRT1122904	hsa-miR-34c-3p	CLIP-seq
MIRT1122905	hsa-miR-3664-3p	CLIP-seq
MIRT1122906	hsa-miR-378	CLIP-seq
MIRT1122907	hsa-miR-378b	CLIP-seq
MIRT1122908	hsa-miR-378c	CLIP-seq
MIRT1122909	hsa-miR-378d	CLIP-seq
MIRT1122910	hsa-miR-378e	CLIP-seq
MIRT1122911	hsa-miR-378f	CLIP-seq
MIRT1122912	hsa-miR-378h	CLIP-seq
MIRT1122913	hsa-miR-378i	CLIP-seq
MIRT1122914	hsa-miR-422a	CLIP-seq
MIRT1122915	hsa-miR-4433	CLIP-seq
MIRT1122916	hsa-miR-4459	CLIP-seq
MIRT1122917	hsa-miR-4638-3p	CLIP-seq
MIRT1122918	hsa-miR-4683	CLIP-seq
MIRT1122919	hsa-miR-4768-3p	CLIP-seq
MIRT1122920	hsa-miR-510	CLIP-seq
MIRT1122921	hsa-miR-512-5p	CLIP-seq
MIRT2265234	hsa-miR-1827	CLIP-seq
MIRT2265235	hsa-miR-2467-3p	CLIP-seq

Show/Hide all(8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001669	Component	Acrosomal vesicle	IBA	21873635
GO:0001669	Component	Acrosomal vesicle	ISS
GO:0005576	Component	Extracellular region	TAS
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS
GO:0007339	Process	Binding of sperm to zona pellucida	IBA	21873635
GO:0031225	Component	Anchored component of membrane	IEA
GO:0045121	Component	Membrane raft	IEA

MIM	HGNC	e!Ensembl
615093	24225	ENSG00000160886

Protein

UniProt ID

Q17RY6

Protein name

Lymphocyte antigen 6K (Ly-6K)

Protein function

Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida (By similarity). May play a role in cell growth (PubMed:18089789).

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Specifically expressed in testis (at protein level). {ECO:0000269|PubMed:12516096, ECO:0000269|PubMed:18089789}.

Sequence

MALLALLLVVALPRVWTDANLTARQRDPEDSQRTDEGDNRVWCHVCERENTFECQNPRRC
KWTEPYCVIAAVKIFPRFFMVAKQCSAGCAAMERPKPEEKRFLLEEPMPFFYLKCCKIRY
CNLEGPPINSSVFKEYAGSMGESCGGLWLAILLLLASIAAGLSLS

Sequence length

165

Interactions

View interactions

	Reactome
			Post-translational modification: synthesis of GPI-anchored proteins

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Gastric ulcer	Gastric ulcer			GWAS

Show/Hide Text Mining Associations (23)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	22988241, 27304060
Breast Neoplasms	Stimulate	26862846
Carcinogenesis	Associate	26862846, 30696738
Carcinoma Ovarian Epithelial	Associate	36768616
Cell Transformation Neoplastic	Stimulate	32055849
Central Nervous System Infections	Associate	26862846
Epstein Barr Virus Infections	Associate	32532891
Esophageal Neoplasms	Associate	32500232
Esophageal Squamous Cell Carcinoma	Associate	18452554
Glioblastoma	Associate	32055849
Lung Diseases	Stimulate	26862846
Lung Neoplasms	Associate	17784873
Neoplasm Metastasis	Associate	22988241, 27304060
Neoplasms	Associate	17784873, 32055849, 37076981, 37628960
Neoplasms	Stimulate	26862846
Neoplasms	Inhibit	32500232
Squamous Cell Carcinoma of Head and Neck	Associate	23481573
Stomach Neoplasms	Associate	24398900
Syndrome	Stimulate	26862846
Urinary Bladder Diseases	Associate	26862846
Urinary Bladder Neoplasms	Associate	21063397
Uterine Cervical Neoplasms	Stimulate	37076981
Uterine Cervicitis	Associate	30696738

LY6K (lymphocyte antigen 6 family member K)