ZNHIT6 (zinc finger HIT-type containing 6)

Gene

• Entrez ID: 54680
• Gene name: Zinc finger HIT-type containing 6
• Gene symbol: ZNHIT6
• Synonyms (NCBI Gene): BCD1, C1orf181, NY-BR-75
• Chromosome: 1
• Chromosome location: 1p22.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022197	hsa-miR-124-3p	Microarray	18668037
MIRT045407	hsa-miR-149-5p	CLASH	23622248
MIRT686180	hsa-miR-4677-3p	HITS-CLIP	23313552
MIRT686179	hsa-miR-6889-3p	HITS-CLIP	23313552
MIRT686178	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT686177	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT686176	hsa-miR-550b-2-5p	HITS-CLIP	23313552
MIRT441516	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT441515	hsa-miR-339-5p	PAR-CLIP	22100165
MIRT441514	hsa-miR-670-5p	PAR-CLIP	22100165
MIRT441516	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT441515	hsa-miR-339-5p	PAR-CLIP	22100165
MIRT441514	hsa-miR-670-5p	PAR-CLIP	22100165
MIRT686180	hsa-miR-4677-3p	HITS-CLIP	23313552
MIRT686179	hsa-miR-6889-3p	HITS-CLIP	23313552
MIRT686178	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT686177	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT686176	hsa-miR-550b-2-5p	HITS-CLIP	23313552
MIRT441516	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT441515	hsa-miR-339-5p	PAR-CLIP	22100165
MIRT441514	hsa-miR-670-5p	PAR-CLIP	22100165
MIRT441516	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT441515	hsa-miR-339-5p	PAR-CLIP	22100165
MIRT441514	hsa-miR-670-5p	PAR-CLIP	22100165
MIRT1542954	hsa-miR-1	CLIP-seq
MIRT1542955	hsa-miR-1208	CLIP-seq
MIRT1542956	hsa-miR-1279	CLIP-seq
MIRT1542957	hsa-miR-128	CLIP-seq
MIRT1542958	hsa-miR-15a	CLIP-seq
MIRT1542959	hsa-miR-15b	CLIP-seq
MIRT1542960	hsa-miR-16	CLIP-seq
MIRT1542961	hsa-miR-195	CLIP-seq
MIRT1542962	hsa-miR-203	CLIP-seq
MIRT1542963	hsa-miR-206	CLIP-seq
MIRT1542964	hsa-miR-25	CLIP-seq
MIRT1542965	hsa-miR-27a	CLIP-seq
MIRT1542966	hsa-miR-27b	CLIP-seq
MIRT1542967	hsa-miR-3145-5p	CLIP-seq
MIRT1542968	hsa-miR-3152-3p	CLIP-seq
MIRT1542969	hsa-miR-3163	CLIP-seq
MIRT1542970	hsa-miR-32	CLIP-seq
MIRT1542971	hsa-miR-323b-3p	CLIP-seq
MIRT1542972	hsa-miR-330-3p	CLIP-seq
MIRT1542973	hsa-miR-34b	CLIP-seq
MIRT1542974	hsa-miR-3545-3p	CLIP-seq
MIRT1542975	hsa-miR-363	CLIP-seq
MIRT1542976	hsa-miR-3653	CLIP-seq
MIRT1542977	hsa-miR-3658	CLIP-seq
MIRT1542978	hsa-miR-367	CLIP-seq
MIRT1542979	hsa-miR-3942-5p	CLIP-seq
MIRT1542980	hsa-miR-410	CLIP-seq
MIRT1542981	hsa-miR-424	CLIP-seq
MIRT1542982	hsa-miR-4282	CLIP-seq
MIRT1542983	hsa-miR-4417	CLIP-seq
MIRT1542984	hsa-miR-4481	CLIP-seq
MIRT1542985	hsa-miR-4693-3p	CLIP-seq
MIRT1542986	hsa-miR-4703-5p	CLIP-seq
MIRT1542987	hsa-miR-4712-3p	CLIP-seq
MIRT1542988	hsa-miR-4745-5p	CLIP-seq
MIRT1542989	hsa-miR-4753-3p	CLIP-seq
MIRT1542990	hsa-miR-497	CLIP-seq
MIRT1542991	hsa-miR-513a-5p	CLIP-seq
MIRT1542992	hsa-miR-582-5p	CLIP-seq
MIRT1542993	hsa-miR-600	CLIP-seq
MIRT1542994	hsa-miR-613	CLIP-seq
MIRT1542995	hsa-miR-888	CLIP-seq
MIRT1542996	hsa-miR-92a	CLIP-seq
MIRT1542997	hsa-miR-92b	CLIP-seq
MIRT1542998	hsa-miR-938	CLIP-seq
MIRT1542999	hsa-miR-942	CLIP-seq
MIRT1542955	hsa-miR-1208	CLIP-seq
MIRT1543000	hsa-miR-129-5p	CLIP-seq
MIRT1543001	hsa-miR-1304	CLIP-seq
MIRT1543002	hsa-miR-1827	CLIP-seq
MIRT1542962	hsa-miR-203	CLIP-seq
MIRT1543003	hsa-miR-22	CLIP-seq
MIRT1543004	hsa-miR-3157-5p	CLIP-seq
MIRT1542969	hsa-miR-3163	CLIP-seq
MIRT1543005	hsa-miR-340	CLIP-seq
MIRT1542973	hsa-miR-34b	CLIP-seq
MIRT1543006	hsa-miR-4312	CLIP-seq
MIRT1543007	hsa-miR-452	CLIP-seq
MIRT1543008	hsa-miR-4676-3p	CLIP-seq
MIRT1543009	hsa-miR-4769-3p	CLIP-seq
MIRT1543010	hsa-miR-4778-5p	CLIP-seq
MIRT1543011	hsa-miR-4797-5p	CLIP-seq
MIRT1543012	hsa-miR-548g	CLIP-seq
MIRT1543013	hsa-miR-558	CLIP-seq
MIRT2163796	hsa-miR-105	CLIP-seq
MIRT1542956	hsa-miR-1279	CLIP-seq
MIRT2163797	hsa-miR-153	CLIP-seq
MIRT2163798	hsa-miR-155	CLIP-seq
MIRT2163799	hsa-miR-2116	CLIP-seq
MIRT1542967	hsa-miR-3145-5p	CLIP-seq
MIRT1542968	hsa-miR-3152-3p	CLIP-seq
MIRT1542971	hsa-miR-323b-3p	CLIP-seq
MIRT2163800	hsa-miR-3614-5p	CLIP-seq
MIRT2163801	hsa-miR-3672	CLIP-seq
MIRT2163802	hsa-miR-448	CLIP-seq
MIRT2163803	hsa-miR-4512	CLIP-seq
MIRT2163804	hsa-miR-4517	CLIP-seq
MIRT2163805	hsa-miR-4645-5p	CLIP-seq
MIRT2163806	hsa-miR-4673	CLIP-seq
MIRT2163807	hsa-miR-4728-3p	CLIP-seq
MIRT2163808	hsa-miR-4733-5p	CLIP-seq
MIRT1543011	hsa-miR-4797-5p	CLIP-seq
MIRT2163809	hsa-miR-515-5p	CLIP-seq
MIRT2163810	hsa-miR-548ac	CLIP-seq
MIRT2163811	hsa-miR-548ae	CLIP-seq
MIRT2163812	hsa-miR-548aj	CLIP-seq
MIRT2163813	hsa-miR-548am	CLIP-seq
MIRT2163814	hsa-miR-548d-3p	CLIP-seq
MIRT2163815	hsa-miR-548x	CLIP-seq
MIRT2163816	hsa-miR-548z	CLIP-seq
MIRT2163817	hsa-miR-668	CLIP-seq
MIRT2163818	hsa-miR-889	CLIP-seq
MIRT2163819	hsa-miR-935	CLIP-seq
MIRT2382997	hsa-miR-1184	CLIP-seq
MIRT2382998	hsa-miR-1205	CLIP-seq
MIRT1542955	hsa-miR-1208	CLIP-seq
MIRT2382999	hsa-miR-1237	CLIP-seq
MIRT2383000	hsa-miR-1272	CLIP-seq
MIRT2383001	hsa-miR-144	CLIP-seq
MIRT2383002	hsa-miR-2467-3p	CLIP-seq
MIRT2383003	hsa-miR-3147	CLIP-seq
MIRT2383004	hsa-miR-3149	CLIP-seq
MIRT1543004	hsa-miR-3157-5p	CLIP-seq
MIRT2383005	hsa-miR-3158-5p	CLIP-seq
MIRT1542969	hsa-miR-3163	CLIP-seq
MIRT2383006	hsa-miR-3678-3p	CLIP-seq
MIRT2383007	hsa-miR-3689a-3p	CLIP-seq
MIRT2383008	hsa-miR-3689c	CLIP-seq
MIRT2383009	hsa-miR-3924	CLIP-seq
MIRT2383010	hsa-miR-3938	CLIP-seq
MIRT2383011	hsa-miR-4252	CLIP-seq
MIRT2383012	hsa-miR-4317	CLIP-seq
MIRT2383013	hsa-miR-4420	CLIP-seq
MIRT2383014	hsa-miR-4425	CLIP-seq
MIRT2383015	hsa-miR-4690-3p	CLIP-seq
MIRT2383016	hsa-miR-4691-3p	CLIP-seq
MIRT2383017	hsa-miR-4694-3p	CLIP-seq
MIRT2383018	hsa-miR-4705	CLIP-seq
MIRT2383019	hsa-miR-4715-3p	CLIP-seq
MIRT2383020	hsa-miR-4722-3p	CLIP-seq
MIRT2383021	hsa-miR-4728-5p	CLIP-seq
MIRT2383022	hsa-miR-4735-5p	CLIP-seq
MIRT2383023	hsa-miR-4763-5p	CLIP-seq
MIRT2383024	hsa-miR-4775	CLIP-seq
MIRT2383025	hsa-miR-4794	CLIP-seq
MIRT2383026	hsa-miR-485-5p	CLIP-seq
MIRT2383027	hsa-miR-488	CLIP-seq
MIRT2383028	hsa-miR-522	CLIP-seq
MIRT2383029	hsa-miR-544	CLIP-seq
MIRT2383030	hsa-miR-548a-3p	CLIP-seq
MIRT2383031	hsa-miR-548e	CLIP-seq
MIRT2383032	hsa-miR-548f	CLIP-seq
MIRT1543012	hsa-miR-548g	CLIP-seq
MIRT2383033	hsa-miR-550a	CLIP-seq
MIRT2383034	hsa-miR-582-3p	CLIP-seq
MIRT2383035	hsa-miR-590-3p	CLIP-seq
MIRT2383036	hsa-miR-660	CLIP-seq
MIRT1542968	hsa-miR-3152-3p	CLIP-seq
MIRT2673507	hsa-miR-10a	CLIP-seq
MIRT2673508	hsa-miR-10b	CLIP-seq
MIRT2673509	hsa-miR-1200	CLIP-seq
MIRT2673510	hsa-miR-1276	CLIP-seq
MIRT2673511	hsa-miR-1303	CLIP-seq
MIRT2673512	hsa-miR-1305	CLIP-seq
MIRT1542967	hsa-miR-3145-5p	CLIP-seq
MIRT2383004	hsa-miR-3149	CLIP-seq
MIRT2673513	hsa-miR-3613-3p	CLIP-seq
MIRT2673514	hsa-miR-3667-5p	CLIP-seq
MIRT2673515	hsa-miR-3688-3p	CLIP-seq
MIRT2673516	hsa-miR-371-5p	CLIP-seq
MIRT2673517	hsa-miR-371b-5p	CLIP-seq
MIRT2673518	hsa-miR-411	CLIP-seq
MIRT2673519	hsa-miR-4325	CLIP-seq
MIRT2673520	hsa-miR-4328	CLIP-seq
MIRT2673521	hsa-miR-4421	CLIP-seq
MIRT2673522	hsa-miR-4486	CLIP-seq
MIRT2673523	hsa-miR-4503	CLIP-seq
MIRT2673524	hsa-miR-4649-5p	CLIP-seq
MIRT2673525	hsa-miR-4684-5p	CLIP-seq
MIRT2383019	hsa-miR-4715-3p	CLIP-seq
MIRT2383020	hsa-miR-4722-3p	CLIP-seq
MIRT2163808	hsa-miR-4733-5p	CLIP-seq
MIRT2383022	hsa-miR-4735-5p	CLIP-seq
MIRT2383023	hsa-miR-4763-5p	CLIP-seq
MIRT2383024	hsa-miR-4775	CLIP-seq
MIRT2673526	hsa-miR-4786-5p	CLIP-seq
MIRT2383025	hsa-miR-4794	CLIP-seq
MIRT2383033	hsa-miR-550a	CLIP-seq
MIRT2673527	hsa-miR-561	CLIP-seq
MIRT2383035	hsa-miR-590-3p	CLIP-seq
MIRT2673528	hsa-miR-593	CLIP-seq
MIRT2673529	hsa-miR-603	CLIP-seq
MIRT2673530	hsa-miR-607	CLIP-seq
MIRT2673531	hsa-miR-661	CLIP-seq
MIRT2673532	hsa-miR-769-5p	CLIP-seq
MIRT2673507	hsa-miR-10a	CLIP-seq
MIRT2673508	hsa-miR-10b	CLIP-seq
MIRT2673510	hsa-miR-1276	CLIP-seq
MIRT2696408	hsa-miR-1294	CLIP-seq
MIRT2696409	hsa-miR-1468	CLIP-seq
MIRT2696410	hsa-miR-1914	CLIP-seq
MIRT2696411	hsa-miR-1976	CLIP-seq
MIRT2696412	hsa-miR-3065-5p	CLIP-seq
MIRT1542967	hsa-miR-3145-5p	CLIP-seq
MIRT2696413	hsa-miR-3168	CLIP-seq
MIRT2696414	hsa-miR-3174	CLIP-seq
MIRT2696415	hsa-miR-3591-5p	CLIP-seq
MIRT2696416	hsa-miR-3606	CLIP-seq
MIRT2673513	hsa-miR-3613-3p	CLIP-seq
MIRT2696417	hsa-miR-3613-5p	CLIP-seq
MIRT2673514	hsa-miR-3667-5p	CLIP-seq
MIRT2673516	hsa-miR-371-5p	CLIP-seq
MIRT2673517	hsa-miR-371b-5p	CLIP-seq
MIRT2696418	hsa-miR-4279	CLIP-seq
MIRT2673519	hsa-miR-4325	CLIP-seq
MIRT2673521	hsa-miR-4421	CLIP-seq
MIRT2696419	hsa-miR-4474-3p	CLIP-seq
MIRT2673522	hsa-miR-4486	CLIP-seq
MIRT2673524	hsa-miR-4649-5p	CLIP-seq
MIRT2673525	hsa-miR-4684-5p	CLIP-seq
MIRT2696420	hsa-miR-4699-5p	CLIP-seq
MIRT2673526	hsa-miR-4786-5p	CLIP-seq
MIRT2696421	hsa-miR-483-5p	CLIP-seq
MIRT2163811	hsa-miR-548ae	CLIP-seq
MIRT2163812	hsa-miR-548aj	CLIP-seq
MIRT2163813	hsa-miR-548am	CLIP-seq
MIRT2163815	hsa-miR-548x	CLIP-seq
MIRT2673527	hsa-miR-561	CLIP-seq
MIRT2673528	hsa-miR-593	CLIP-seq
MIRT2673531	hsa-miR-661	CLIP-seq
MIRT2673532	hsa-miR-769-5p	CLIP-seq
MIRT2696422	hsa-miR-921	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000463	Process	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA
GO:0000492	Process	Box C/D snoRNP assembly	IBA
GO:0000492	Process	Box C/D snoRNP assembly	IMP	17636026
GO:0001094	Function	TFIID-class transcription factor complex binding	IPI	17636026
GO:0005515	Function	Protein binding	IPI	17636026, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0019899	Function	Enzyme binding	IPI	23382074
GO:0042254	Process	Ribosome biogenesis	IEA
GO:0042802	Function	Identical protein binding	IPI	17636026
GO:0046872	Function	Metal ion binding	IEA
GO:0048254	Process	SnoRNA localization	IMP	17636026
GO:0051117	Function	ATPase binding	IPI	17636026
GO:0051259	Process	Protein complex oligomerization	IMP	17636026
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:0070761	Component	Pre-snoRNP complex	IBA
GO:0070761	Component	Pre-snoRNP complex	IDA	17636026

Other IDs

• MIM: 620473
• HGNC: 26089
• e!Ensembl: ENSG00000117174

Protein

• UniProt ID: Q9NWK9
• Protein name: Box C/D snoRNA protein 1 (Serologically defined breast cancer antigen NY-BR-75) (Zinc finger HIT domain-containing protein 6)
• Protein function: Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04438	zf-HIT	216 → 246	HIT zinc finger	Domain

• Sequence:

  MEFAAENEGKSGGGLHSVAEGVRLSPEPGREGVRDLAGAEEFGGGEEGTGLTGIKEIGDG
  EEGSGQRPEEIPMDLTVVKQEIIDWPGTEGRLAGQWVEQEVEDRPEVKDENAGVLEVKQE
  TDSSLVVKEAKVGEPEVKEEKVKEEVMDWSEVKEEKDNLEIKQEEKFVGQCIKEELMHGE
  CVKEEKDFLKKEIVDDTKVKEEPPINHPVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSC
  SLPCVKKHKAELTCNGVRDKTAYISIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKRP
  ISNKYMYFMKNRARRQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAEYI
  EKRVPDDKTINEILKPYIDPEKSDPVIRQRLKAYIRSQTGVQILMKIEYMQQNLVRYYEL
  DPYKSLLDNLRNKVIIEYPTLHVVLKGSNNDMKVLHQVKSESTKNVGNEN

• Sequence length: 470