LRRN3 (leucine rich repeat neuronal 3)

Gene
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
54674
Gene name Gene Name - the full gene name approved by the HGNC.
Leucine rich repeat neuronal 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
LRRN3
Synonyms (NCBI Gene) Gene synonyms aliases
FIGLER5, NLRR-3, NLRR3
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7q31.1
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Show/Hide all(2)
miRTarBase ID miRNA Experiments Reference
MIRT025063 hsa-miR-181a-5p Microarray 17612493
MIRT2034242 hsa-miR-4698 CLIP-seq
Transcription factors
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Show/Hide all(2)
Transcription factor Regulation Reference
MYCN Repression 21908575
PIAS2 Repression 21908575
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Show/Hide all(4)
GO ID Ontology Definition Evidence Reference
GO:0005615 Component Extracellular space IBA 21873635
GO:0016021 Component Integral component of membrane IEA
GO:0031012 Component Extracellular matrix IBA 21873635
GO:0051965 Process Positive regulation of synapse assembly IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
619748 17200 ENSG00000173114
Protein
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9H3W5
Protein name Leucine-rich repeat neuronal protein 3 (Neuronal leucine-rich repeat protein 3) (NLRR-3)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13855 LRR_8 116 → 176 Leucine rich repeat Repeat
PF13855 LRR_8 164 → 223 Leucine rich repeat Repeat
PF13855 LRR_8 212 → 272 Leucine rich repeat Repeat
PF13855 LRR_8 309 → 370 Leucine rich repeat Repeat
PF07679 I-set 425 → 513 Immunoglobulin I-set domain Domain
PF00041 fn3 525 → 599 Fibronectin type III domain Domain
Sequence 
MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGL
LTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLS
VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN
SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES
ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISI
DSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNL
KEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICL
PLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGT
LDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVS
WKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQ
KNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHS
YVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS
Sequence length 708
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (2)
Causal
Disease term Disease name dbSNP ID References
Autism spectrum disorder Autism Spectrum Disorders rs724159978, rs75184679, rs119103221, rs9332964, rs121912562, rs1594344233, rs727504317, rs111033204, rs1801086, rs587784464, rs724159948, rs764659822, rs794727977, rs796052733, rs796052728
View all (51 more)		 20678249
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)		 30285260
Show/Hide Text Mining Associations (8)
Associations from Text Mining
Disease Name Relationship Type References
Heart Failure Associate 31059043, 34857156
HIV Infections Associate 23717651, 32579550
Lung Neoplasms Associate 25556184
Lymphoma Mantle Cell Associate 32961552
Parkinson Disease Associate 31199560
Sarcopenia Associate 34371826
Smoke Inhalation Injury Associate 25556184, 27154971
Stroke Associate 31436916