Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	54549
Gene name	Sidekick cell adhesion molecule 2
Gene symbol	SDK2
Synonyms (NCBI Gene)	-
Chromosome	17
Chromosome location	17q25.1
Summary	The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular pro

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miRTarBase ID	miRNA	Experiments	Reference
MIRT721753	hsa-miR-3162-3p	HITS-CLIP	19536157
MIRT721752	hsa-miR-6795-5p	HITS-CLIP	19536157
MIRT721751	hsa-miR-6887-5p	HITS-CLIP	19536157
MIRT721750	hsa-miR-328-5p	HITS-CLIP	19536157
MIRT721749	hsa-miR-6885-5p	HITS-CLIP	19536157
MIRT721748	hsa-miR-193b-5p	HITS-CLIP	19536157
MIRT721747	hsa-miR-491-5p	HITS-CLIP	19536157
MIRT721746	hsa-miR-3151-5p	HITS-CLIP	19536157
MIRT721745	hsa-miR-4447	HITS-CLIP	19536157
MIRT721744	hsa-miR-4472	HITS-CLIP	19536157
MIRT721743	hsa-miR-6742-5p	HITS-CLIP	19536157
MIRT721742	hsa-miR-4713-5p	HITS-CLIP	19536157
MIRT721741	hsa-miR-6867-3p	HITS-CLIP	19536157
MIRT721740	hsa-miR-7109-5p	HITS-CLIP	19536157
MIRT721739	hsa-miR-4265	HITS-CLIP	19536157
MIRT721738	hsa-miR-4296	HITS-CLIP	19536157
MIRT721737	hsa-miR-4322	HITS-CLIP	19536157
MIRT721736	hsa-miR-6796-5p	HITS-CLIP	19536157
MIRT721735	hsa-miR-6759-5p	HITS-CLIP	19536157
MIRT721734	hsa-miR-629-3p	HITS-CLIP	19536157
MIRT707208	hsa-miR-576-3p	HITS-CLIP	21572407
MIRT707207	hsa-miR-6871-5p	HITS-CLIP	21572407
MIRT707206	hsa-miR-6878-5p	HITS-CLIP	21572407
MIRT707204	hsa-miR-6731-5p	HITS-CLIP	21572407
MIRT707205	hsa-miR-8085	HITS-CLIP	21572407
MIRT707203	hsa-miR-3911	HITS-CLIP	21572407
MIRT707202	hsa-miR-644a	HITS-CLIP	21572407
MIRT707201	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT707200	hsa-miR-30c-1-3p	HITS-CLIP	21572407
MIRT707199	hsa-miR-30c-2-3p	HITS-CLIP	21572407
MIRT707198	hsa-miR-6788-5p	HITS-CLIP	21572407
MIRT707197	hsa-miR-147a	HITS-CLIP	21572407
MIRT707196	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT707196	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT707196	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT707201	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT707201	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT721753	hsa-miR-3162-3p	HITS-CLIP	19536157
MIRT721752	hsa-miR-6795-5p	HITS-CLIP	19536157
MIRT721751	hsa-miR-6887-5p	HITS-CLIP	19536157
MIRT721750	hsa-miR-328-5p	HITS-CLIP	19536157
MIRT721749	hsa-miR-6885-5p	HITS-CLIP	19536157
MIRT721748	hsa-miR-193b-5p	HITS-CLIP	19536157
MIRT721747	hsa-miR-491-5p	HITS-CLIP	19536157
MIRT721746	hsa-miR-3151-5p	HITS-CLIP	19536157
MIRT721745	hsa-miR-4447	HITS-CLIP	19536157
MIRT721744	hsa-miR-4472	HITS-CLIP	19536157
MIRT721743	hsa-miR-6742-5p	HITS-CLIP	19536157
MIRT721742	hsa-miR-4713-5p	HITS-CLIP	19536157
MIRT721741	hsa-miR-6867-3p	HITS-CLIP	19536157
MIRT721740	hsa-miR-7109-5p	HITS-CLIP	19536157
MIRT721739	hsa-miR-4265	HITS-CLIP	19536157
MIRT721738	hsa-miR-4296	HITS-CLIP	19536157
MIRT721737	hsa-miR-4322	HITS-CLIP	19536157
MIRT721736	hsa-miR-6796-5p	HITS-CLIP	19536157
MIRT721735	hsa-miR-6759-5p	HITS-CLIP	19536157
MIRT721734	hsa-miR-629-3p	HITS-CLIP	19536157
MIRT707208	hsa-miR-576-3p	HITS-CLIP	21572407
MIRT707207	hsa-miR-6871-5p	HITS-CLIP	21572407
MIRT707206	hsa-miR-6878-5p	HITS-CLIP	21572407
MIRT707204	hsa-miR-6731-5p	HITS-CLIP	21572407
MIRT707205	hsa-miR-8085	HITS-CLIP	21572407
MIRT707203	hsa-miR-3911	HITS-CLIP	21572407
MIRT707202	hsa-miR-644a	HITS-CLIP	21572407
MIRT707201	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT707200	hsa-miR-30c-1-3p	HITS-CLIP	21572407
MIRT707199	hsa-miR-30c-2-3p	HITS-CLIP	21572407
MIRT707198	hsa-miR-6788-5p	HITS-CLIP	21572407
MIRT707197	hsa-miR-147a	HITS-CLIP	21572407
MIRT707196	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT1331937	hsa-miR-1207-5p	CLIP-seq
MIRT1331938	hsa-miR-1237	CLIP-seq
MIRT1331939	hsa-miR-1248	CLIP-seq
MIRT1331940	hsa-miR-1255a	CLIP-seq
MIRT1331941	hsa-miR-1255b	CLIP-seq
MIRT1331942	hsa-miR-1273f	CLIP-seq
MIRT1331943	hsa-miR-1283	CLIP-seq
MIRT1331944	hsa-miR-1291	CLIP-seq
MIRT1331945	hsa-miR-1299	CLIP-seq
MIRT1331946	hsa-miR-147	CLIP-seq
MIRT1331947	hsa-miR-1470	CLIP-seq
MIRT1331948	hsa-miR-1909	CLIP-seq
MIRT1331949	hsa-miR-2467-5p	CLIP-seq
MIRT1331950	hsa-miR-3120-5p	CLIP-seq
MIRT1331951	hsa-miR-3148	CLIP-seq
MIRT1331952	hsa-miR-3175	CLIP-seq
MIRT1331953	hsa-miR-3176	CLIP-seq
MIRT1331954	hsa-miR-3179	CLIP-seq
MIRT1331955	hsa-miR-3184	CLIP-seq
MIRT1331956	hsa-miR-3188	CLIP-seq
MIRT1331957	hsa-miR-3202	CLIP-seq
MIRT1331958	hsa-miR-326	CLIP-seq
MIRT1331959	hsa-miR-330-5p	CLIP-seq
MIRT1331960	hsa-miR-346	CLIP-seq
MIRT1331961	hsa-miR-3652	CLIP-seq
MIRT1331962	hsa-miR-3664-3p	CLIP-seq
MIRT1331963	hsa-miR-3689d	CLIP-seq
MIRT1331964	hsa-miR-3690	CLIP-seq
MIRT1331965	hsa-miR-376c	CLIP-seq
MIRT1331966	hsa-miR-3918	CLIP-seq
MIRT1331967	hsa-miR-3922-3p	CLIP-seq
MIRT1331968	hsa-miR-3973	CLIP-seq
MIRT1331969	hsa-miR-3975	CLIP-seq
MIRT1331970	hsa-miR-3976	CLIP-seq
MIRT1331971	hsa-miR-423-5p	CLIP-seq
MIRT1331972	hsa-miR-425	CLIP-seq
MIRT1331973	hsa-miR-4254	CLIP-seq
MIRT1331974	hsa-miR-4283	CLIP-seq
MIRT1331975	hsa-miR-4288	CLIP-seq
MIRT1331976	hsa-miR-4421	CLIP-seq
MIRT1331977	hsa-miR-4430	CLIP-seq
MIRT1331978	hsa-miR-4433	CLIP-seq
MIRT1331979	hsa-miR-4434	CLIP-seq
MIRT1331980	hsa-miR-4436b-3p	CLIP-seq
MIRT1331981	hsa-miR-4455	CLIP-seq
MIRT1331982	hsa-miR-4459	CLIP-seq
MIRT1331983	hsa-miR-4468	CLIP-seq
MIRT1331984	hsa-miR-4469	CLIP-seq
MIRT1331985	hsa-miR-4474-3p	CLIP-seq
MIRT1331986	hsa-miR-448	CLIP-seq
MIRT1331987	hsa-miR-4489	CLIP-seq
MIRT1331988	hsa-miR-4492	CLIP-seq
MIRT1331989	hsa-miR-4498	CLIP-seq
MIRT1331990	hsa-miR-4505	CLIP-seq
MIRT1331991	hsa-miR-4516	CLIP-seq
MIRT1331992	hsa-miR-4533	CLIP-seq
MIRT1331993	hsa-miR-4539	CLIP-seq
MIRT1331994	hsa-miR-4640-5p	CLIP-seq
MIRT1331995	hsa-miR-4642	CLIP-seq
MIRT1331996	hsa-miR-4663	CLIP-seq
MIRT1331997	hsa-miR-4667-3p	CLIP-seq
MIRT1331998	hsa-miR-4675	CLIP-seq
MIRT1331999	hsa-miR-4720-5p	CLIP-seq
MIRT1332000	hsa-miR-4726-5p	CLIP-seq
MIRT1332001	hsa-miR-4731-5p	CLIP-seq
MIRT1332002	hsa-miR-4741	CLIP-seq
MIRT1332003	hsa-miR-4763-3p	CLIP-seq
MIRT1332004	hsa-miR-4768-3p	CLIP-seq
MIRT1332005	hsa-miR-4782-5p	CLIP-seq
MIRT1332006	hsa-miR-4799-3p	CLIP-seq
MIRT1332007	hsa-miR-485-5p	CLIP-seq
MIRT1332008	hsa-miR-486-3p	CLIP-seq
MIRT1332009	hsa-miR-510	CLIP-seq
MIRT1332010	hsa-miR-520d-5p	CLIP-seq
MIRT1332011	hsa-miR-520g	CLIP-seq
MIRT1332012	hsa-miR-520h	CLIP-seq
MIRT1332013	hsa-miR-524-5p	CLIP-seq
MIRT1332014	hsa-miR-564	CLIP-seq
MIRT1332015	hsa-miR-599	CLIP-seq
MIRT1332016	hsa-miR-609	CLIP-seq
MIRT1332017	hsa-miR-616	CLIP-seq
MIRT1332018	hsa-miR-632	CLIP-seq
MIRT1332019	hsa-miR-635	CLIP-seq
MIRT1332020	hsa-miR-762	CLIP-seq
MIRT1332021	hsa-miR-875-3p	CLIP-seq
MIRT1332022	hsa-miR-9	CLIP-seq
MIRT1331937	hsa-miR-1207-5p	CLIP-seq
MIRT1331943	hsa-miR-1283	CLIP-seq
MIRT1331966	hsa-miR-3918	CLIP-seq
MIRT1553285	hsa-miR-4318	CLIP-seq
MIRT1331980	hsa-miR-4436b-3p	CLIP-seq
MIRT1331992	hsa-miR-4533	CLIP-seq
MIRT1332003	hsa-miR-4763-3p	CLIP-seq
MIRT1332010	hsa-miR-520d-5p	CLIP-seq
MIRT1332013	hsa-miR-524-5p	CLIP-seq
MIRT1553286	hsa-miR-759	CLIP-seq
MIRT1331937	hsa-miR-1207-5p	CLIP-seq
MIRT1331943	hsa-miR-1283	CLIP-seq
MIRT1331966	hsa-miR-3918	CLIP-seq
MIRT1331980	hsa-miR-4436b-3p	CLIP-seq
MIRT1332003	hsa-miR-4763-3p	CLIP-seq
MIRT1332010	hsa-miR-520d-5p	CLIP-seq
MIRT1332013	hsa-miR-524-5p	CLIP-seq
MIRT1331937	hsa-miR-1207-5p	CLIP-seq
MIRT1331943	hsa-miR-1283	CLIP-seq
MIRT2098108	hsa-miR-1289	CLIP-seq
MIRT1331945	hsa-miR-1299	CLIP-seq
MIRT2098109	hsa-miR-132	CLIP-seq
MIRT1331948	hsa-miR-1909	CLIP-seq
MIRT2098110	hsa-miR-212	CLIP-seq
MIRT2098111	hsa-miR-3134	CLIP-seq
MIRT2098112	hsa-miR-3198	CLIP-seq
MIRT1331958	hsa-miR-326	CLIP-seq
MIRT1331959	hsa-miR-330-5p	CLIP-seq
MIRT1331966	hsa-miR-3918	CLIP-seq
MIRT2098113	hsa-miR-3925-5p	CLIP-seq
MIRT2098114	hsa-miR-4294	CLIP-seq
MIRT2098115	hsa-miR-4309	CLIP-seq
MIRT2098116	hsa-miR-4311	CLIP-seq
MIRT1331980	hsa-miR-4436b-3p	CLIP-seq
MIRT1331986	hsa-miR-448	CLIP-seq
MIRT1331994	hsa-miR-4640-5p	CLIP-seq
MIRT2098117	hsa-miR-4701-5p	CLIP-seq
MIRT2098118	hsa-miR-4709-3p	CLIP-seq
MIRT1332000	hsa-miR-4726-5p	CLIP-seq
MIRT2098119	hsa-miR-4736	CLIP-seq
MIRT2098120	hsa-miR-4762-5p	CLIP-seq
MIRT1332003	hsa-miR-4763-3p	CLIP-seq
MIRT2098121	hsa-miR-4773	CLIP-seq
MIRT2098122	hsa-miR-4777-5p	CLIP-seq
MIRT1332005	hsa-miR-4782-5p	CLIP-seq
MIRT2098123	hsa-miR-502-5p	CLIP-seq
MIRT2098124	hsa-miR-516b	CLIP-seq
MIRT1332010	hsa-miR-520d-5p	CLIP-seq
MIRT1332013	hsa-miR-524-5p	CLIP-seq
MIRT2098125	hsa-miR-558	CLIP-seq
MIRT2098126	hsa-miR-588	CLIP-seq
MIRT1332019	hsa-miR-635	CLIP-seq
MIRT2098127	hsa-miR-7	CLIP-seq
MIRT1331937	hsa-miR-1207-5p	CLIP-seq
MIRT2322829	hsa-miR-1238	CLIP-seq
MIRT1331940	hsa-miR-1255a	CLIP-seq
MIRT1331941	hsa-miR-1255b	CLIP-seq
MIRT2322830	hsa-miR-1343	CLIP-seq
MIRT2322831	hsa-miR-1827	CLIP-seq
MIRT1331948	hsa-miR-1909	CLIP-seq
MIRT1331949	hsa-miR-2467-5p	CLIP-seq
MIRT2322832	hsa-miR-2682	CLIP-seq
MIRT2322833	hsa-miR-3156-3p	CLIP-seq
MIRT1331955	hsa-miR-3184	CLIP-seq
MIRT1331956	hsa-miR-3188	CLIP-seq
MIRT1331958	hsa-miR-326	CLIP-seq
MIRT1331959	hsa-miR-330-5p	CLIP-seq
MIRT2322834	hsa-miR-34a	CLIP-seq
MIRT2322835	hsa-miR-34c-5p	CLIP-seq
MIRT2322836	hsa-miR-3682-5p	CLIP-seq
MIRT1331964	hsa-miR-3690	CLIP-seq
MIRT1331969	hsa-miR-3975	CLIP-seq
MIRT1331971	hsa-miR-423-5p	CLIP-seq
MIRT1331973	hsa-miR-4254	CLIP-seq
MIRT2098114	hsa-miR-4294	CLIP-seq
MIRT2322837	hsa-miR-4301	CLIP-seq
MIRT1331980	hsa-miR-4436b-3p	CLIP-seq
MIRT2322838	hsa-miR-449a	CLIP-seq
MIRT2322839	hsa-miR-449b	CLIP-seq
MIRT2322840	hsa-miR-449c	CLIP-seq
MIRT2322841	hsa-miR-450b-5p	CLIP-seq
MIRT2322842	hsa-miR-4514	CLIP-seq
MIRT1331994	hsa-miR-4640-5p	CLIP-seq
MIRT2322843	hsa-miR-4688	CLIP-seq
MIRT2322844	hsa-miR-4692	CLIP-seq
MIRT2322845	hsa-miR-4710	CLIP-seq
MIRT1332000	hsa-miR-4726-5p	CLIP-seq
MIRT2322846	hsa-miR-4753-3p	CLIP-seq
MIRT1332003	hsa-miR-4763-3p	CLIP-seq
MIRT1332005	hsa-miR-4782-5p	CLIP-seq
MIRT2322847	hsa-miR-4799-5p	CLIP-seq
MIRT1332007	hsa-miR-485-5p	CLIP-seq
MIRT1332008	hsa-miR-486-3p	CLIP-seq
MIRT2098124	hsa-miR-516b	CLIP-seq
MIRT2322848	hsa-miR-518a-5p	CLIP-seq
MIRT2322849	hsa-miR-527	CLIP-seq
MIRT2322850	hsa-miR-629	CLIP-seq
MIRT1332019	hsa-miR-635	CLIP-seq
MIRT2322851	hsa-miR-661	CLIP-seq
MIRT2394141	hsa-miR-1915	CLIP-seq
MIRT2394142	hsa-miR-4419a	CLIP-seq
MIRT2394143	hsa-miR-4510	CLIP-seq
MIRT2459000	hsa-miR-2115	CLIP-seq
MIRT2459001	hsa-miR-378g	CLIP-seq
MIRT2459002	hsa-miR-4267	CLIP-seq
MIRT1331985	hsa-miR-4474-3p	CLIP-seq
MIRT2459003	hsa-miR-4650-5p	CLIP-seq
MIRT2322851	hsa-miR-661	CLIP-seq

Show/Hide all (18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0007155	Process	Cell adhesion	IEA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IBA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IEA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	ISS
GO:0007416	Process	Synapse assembly	IBA
GO:0007416	Process	Synapse assembly	IEA
GO:0007416	Process	Synapse assembly	ISS
GO:0010842	Process	Retina layer formation	IEA
GO:0010842	Process	Retina layer formation	ISS
GO:0016020	Component	Membrane	IEA
GO:0045202	Component	Synapse	IBA
GO:0045202	Component	Synapse	IEA
GO:0045202	Component	Synapse	ISS
GO:0060219	Process	Camera-type eye photoreceptor cell differentiation	IEA
GO:0060219	Process	Camera-type eye photoreceptor cell differentiation	ISS

MIM	HGNC	e!Ensembl
607217	19308	ENSG00000069188

Q58EX2

Protein name

Protein sidekick-2

Protein function

Adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion. Acts by promoting formation of synapses between two specific retinal cell

PDB

1WF5 , 1WFN , 1WFO , 1WIS

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07679	I-set	114 → 203	Immunoglobulin I-set domain	Domain
PF13927	Ig_3	214 → 287		Domain
PF07679	I-set	308 → 397	Immunoglobulin I-set domain	Domain
PF07679	I-set	402 → 492	Immunoglobulin I-set domain	Domain
PF13927	Ig_3	497 → 573		Domain
PF00041	fn3	592 → 677	Fibronectin type III domain	Domain
PF00041	fn3	692 → 779	Fibronectin type III domain	Domain
PF00041	fn3	793 → 883	Fibronectin type III domain	Domain
PF00041	fn3	896 → 980	Fibronectin type III domain	Domain
PF00041	fn3	994 → 1083	Fibronectin type III domain	Domain
PF00041	fn3	1098 → 1187	Fibronectin type III domain	Domain
PF00041	fn3	1201 → 1288	Fibronectin type III domain	Domain
PF00041	fn3	1302 → 1387	Fibronectin type III domain	Domain
PF00041	fn3	1402 → 1488	Fibronectin type III domain	Domain
PF00041	fn3	1503 → 1611	Fibronectin type III domain	Domain
PF00041	fn3	1625 → 1712	Fibronectin type III domain	Domain
PF00041	fn3	1725 → 1811	Fibronectin type III domain	Domain
PF00041	fn3	1825 → 1912	Fibronectin type III domain	Domain

Sequence

MWGLLIWTLLALHQIRAARAQDDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKW
LHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEK
HQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGR
YYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVAN
ARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGA
YLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR
NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVV
LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS
RGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT
ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATL
STVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARS
YQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQN
GILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSS
KVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEV
TMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGH
LSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTA
LTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGK
TSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTS
PPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSR
SDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPS
SGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRS
AQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLI
WQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTR
KGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTR
ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAA
PDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNP
GATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGE
AVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFL
AENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSV
NVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFR
IRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIE
ARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPA
QKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGALGHSEM
MSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDLIPAE
SSSLTEKPSEISDSQGSDSEYEVDSNHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAY
SYTESDSGEPDHTTVTNSTSTQQGSLFRPKASRTPTPQNPPNPPSQQSTLYRPPSSLAPG
SRAPIAGFSSFV

Sequence length

2172

Interactions

View interactions

	Reactome
			SDK interactions

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Likely benign	rs35867741	RCV005929490
Familial cancer of breast	Uncertain significance	rs541836618	RCV005932552
Gastric cancer	Likely benign	rs35867741	RCV005929492
Malignant tumor of esophagus	Likely benign; Uncertain significance	rs35867741, rs144120477	RCV005929491 RCV005939187
Ovarian serous cystadenocarcinoma	Likely benign	rs35867741	RCV005929493
SDK2-related disorder	Uncertain significance; Likely benign; Benign	rs200185560, rs143280778, rs143251430, rs137921116, rs139142614, rs778945510, rs751184995, rs117291342, rs146398103, rs374117631, rs2511331279, rs78185984, rs115502230, rs139527427, rs138527765 View all (30 more)	RCV003946345 RCV003928905 RCV003954154 RCV003909291 RCV003906990 RCV003924031 RCV003974485 RCV003974075 RCV003979546 RCV003901667 RCV003902063 RCV003979323 RCV003973956 RCV003974005 RCV003911541 RCV003909601 RCV003914156 RCV003933872 RCV003944123 RCV003961653 RCV003954320 RCV003939514 RCV003939637 RCV003939768 RCV003934747 RCV003949697 RCV003937033 RCV003949297 RCV003951499 RCV003947200 RCV003959117 RCV003954755 RCV003922260 RCV003926876 RCV003936846 RCV003942207 RCV003944257 RCV003946762 RCV003946861 RCV003952300 RCV003956822 RCV003976614 RCV003968976 RCV003981353 RCV003938602
See cases	Uncertain significance	rs144452885, rs144141099	RCV001291638 RCV001291639

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Medulloblastoma	Associate	36273157
Neoplasms	Associate	36273157

SDK2 (sidekick cell adhesion molecule 2)