ANKRD16 (ankyrin repeat domain 16)

Gene

• Entrez ID: 54522
• Gene name: Ankyrin repeat domain 16
• Gene symbol: ANKRD16
• Synonyms (NCBI Gene): -
• Chromosome: 10
• Chromosome location: 10p15.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT782893	hsa-miR-1254	CLIP-seq
MIRT782894	hsa-miR-1270	CLIP-seq
MIRT782895	hsa-miR-129-5p	CLIP-seq
MIRT782896	hsa-miR-197	CLIP-seq
MIRT782897	hsa-miR-1976	CLIP-seq
MIRT782898	hsa-miR-3116	CLIP-seq
MIRT782899	hsa-miR-3199	CLIP-seq
MIRT782900	hsa-miR-412	CLIP-seq
MIRT782901	hsa-miR-4258	CLIP-seq
MIRT782902	hsa-miR-4294	CLIP-seq
MIRT782903	hsa-miR-431	CLIP-seq
MIRT782904	hsa-miR-433	CLIP-seq
MIRT782905	hsa-miR-4438	CLIP-seq
MIRT782906	hsa-miR-4531	CLIP-seq
MIRT782907	hsa-miR-5095	CLIP-seq
MIRT782908	hsa-miR-617	CLIP-seq
MIRT782909	hsa-miR-620	CLIP-seq
MIRT782910	hsa-miR-661	CLIP-seq
MIRT782911	hsa-miR-924	CLIP-seq
MIRT1931036	hsa-miR-1193	CLIP-seq
MIRT1931037	hsa-miR-1200	CLIP-seq
MIRT1931038	hsa-miR-1234	CLIP-seq
MIRT782893	hsa-miR-1254	CLIP-seq
MIRT1931039	hsa-miR-150	CLIP-seq
MIRT782896	hsa-miR-197	CLIP-seq
MIRT782897	hsa-miR-1976	CLIP-seq
MIRT1931040	hsa-miR-2113	CLIP-seq
MIRT1931041	hsa-miR-2392	CLIP-seq
MIRT782898	hsa-miR-3116	CLIP-seq
MIRT782899	hsa-miR-3199	CLIP-seq
MIRT782901	hsa-miR-4258	CLIP-seq
MIRT1931042	hsa-miR-4307	CLIP-seq
MIRT1931043	hsa-miR-4324	CLIP-seq
MIRT782905	hsa-miR-4438	CLIP-seq
MIRT1931044	hsa-miR-4662a-5p	CLIP-seq
MIRT1931045	hsa-miR-4676-5p	CLIP-seq
MIRT1931046	hsa-miR-4735-5p	CLIP-seq
MIRT1931047	hsa-miR-4775	CLIP-seq
MIRT1931048	hsa-miR-4794	CLIP-seq
MIRT782907	hsa-miR-5095	CLIP-seq
MIRT1931049	hsa-miR-5096	CLIP-seq
MIRT1931050	hsa-miR-520g	CLIP-seq
MIRT1931051	hsa-miR-520h	CLIP-seq
MIRT1931052	hsa-miR-544b	CLIP-seq
MIRT1931053	hsa-miR-575	CLIP-seq
MIRT1931054	hsa-miR-590-3p	CLIP-seq
MIRT1931055	hsa-miR-599	CLIP-seq
MIRT782910	hsa-miR-661	CLIP-seq
MIRT1931056	hsa-miR-892a	CLIP-seq
MIRT2171614	hsa-miR-106a	CLIP-seq
MIRT2171615	hsa-miR-106b	CLIP-seq
MIRT2171616	hsa-miR-1179	CLIP-seq
MIRT1931037	hsa-miR-1200	CLIP-seq
MIRT2171617	hsa-miR-122	CLIP-seq
MIRT1931038	hsa-miR-1234	CLIP-seq
MIRT2171618	hsa-miR-124	CLIP-seq
MIRT782893	hsa-miR-1254	CLIP-seq
MIRT2171619	hsa-miR-1258	CLIP-seq
MIRT2171620	hsa-miR-1267	CLIP-seq
MIRT1931039	hsa-miR-150	CLIP-seq
MIRT2171621	hsa-miR-17	CLIP-seq
MIRT2171622	hsa-miR-1827	CLIP-seq
MIRT782897	hsa-miR-1976	CLIP-seq
MIRT2171623	hsa-miR-20a	CLIP-seq
MIRT2171624	hsa-miR-20b	CLIP-seq
MIRT2171625	hsa-miR-223	CLIP-seq
MIRT2171626	hsa-miR-2467-3p	CLIP-seq
MIRT2171627	hsa-miR-27a	CLIP-seq
MIRT2171628	hsa-miR-27b	CLIP-seq
MIRT2171629	hsa-miR-298	CLIP-seq
MIRT2171630	hsa-miR-302a	CLIP-seq
MIRT2171631	hsa-miR-302b	CLIP-seq
MIRT2171632	hsa-miR-302c	CLIP-seq
MIRT2171633	hsa-miR-302d	CLIP-seq
MIRT2171634	hsa-miR-302e	CLIP-seq
MIRT782898	hsa-miR-3116	CLIP-seq
MIRT2171635	hsa-miR-3127-5p	CLIP-seq
MIRT2171636	hsa-miR-3135b	CLIP-seq
MIRT2171637	hsa-miR-3194-3p	CLIP-seq
MIRT782899	hsa-miR-3199	CLIP-seq
MIRT2171638	hsa-miR-3652	CLIP-seq
MIRT2171639	hsa-miR-372	CLIP-seq
MIRT2171640	hsa-miR-373	CLIP-seq
MIRT2171641	hsa-miR-3918	CLIP-seq
MIRT782901	hsa-miR-4258	CLIP-seq
MIRT2171642	hsa-miR-4279	CLIP-seq
MIRT782902	hsa-miR-4294	CLIP-seq
MIRT782903	hsa-miR-431	CLIP-seq
MIRT2171643	hsa-miR-4310	CLIP-seq
MIRT1931043	hsa-miR-4324	CLIP-seq
MIRT2171644	hsa-miR-4328	CLIP-seq
MIRT782904	hsa-miR-433	CLIP-seq
MIRT2171645	hsa-miR-4423-3p	CLIP-seq
MIRT2171646	hsa-miR-4423-5p	CLIP-seq
MIRT2171647	hsa-miR-4430	CLIP-seq
MIRT2171648	hsa-miR-4436b-3p	CLIP-seq
MIRT782905	hsa-miR-4438	CLIP-seq
MIRT2171649	hsa-miR-4722-3p	CLIP-seq
MIRT2171650	hsa-miR-4731-5p	CLIP-seq
MIRT1931046	hsa-miR-4735-5p	CLIP-seq
MIRT2171651	hsa-miR-4772-5p	CLIP-seq
MIRT1931047	hsa-miR-4775	CLIP-seq
MIRT2171652	hsa-miR-4793-5p	CLIP-seq
MIRT1931048	hsa-miR-4794	CLIP-seq
MIRT2171653	hsa-miR-506	CLIP-seq
MIRT782907	hsa-miR-5095	CLIP-seq
MIRT2171654	hsa-miR-512-3p	CLIP-seq
MIRT2171655	hsa-miR-513a-5p	CLIP-seq
MIRT2171656	hsa-miR-519d	CLIP-seq
MIRT2171657	hsa-miR-520a-3p	CLIP-seq
MIRT2171658	hsa-miR-520b	CLIP-seq
MIRT2171659	hsa-miR-520c-3p	CLIP-seq
MIRT2171660	hsa-miR-520d-3p	CLIP-seq
MIRT2171661	hsa-miR-520e	CLIP-seq
MIRT1931050	hsa-miR-520g	CLIP-seq
MIRT1931051	hsa-miR-520h	CLIP-seq
MIRT1931052	hsa-miR-544b	CLIP-seq
MIRT1931054	hsa-miR-590-3p	CLIP-seq
MIRT782910	hsa-miR-661	CLIP-seq
MIRT782911	hsa-miR-924	CLIP-seq
MIRT2171662	hsa-miR-93	CLIP-seq
MIRT782893	hsa-miR-1254	CLIP-seq
MIRT782898	hsa-miR-3116	CLIP-seq
MIRT1931046	hsa-miR-4735-5p	CLIP-seq
MIRT1931047	hsa-miR-4775	CLIP-seq
MIRT1931048	hsa-miR-4794	CLIP-seq
MIRT1931054	hsa-miR-590-3p	CLIP-seq
MIRT782910	hsa-miR-661	CLIP-seq
MIRT782893	hsa-miR-1254	CLIP-seq
MIRT782895	hsa-miR-129-5p	CLIP-seq
MIRT782898	hsa-miR-3116	CLIP-seq
MIRT2474692	hsa-miR-3149	CLIP-seq
MIRT2171637	hsa-miR-3194-3p	CLIP-seq
MIRT782899	hsa-miR-3199	CLIP-seq
MIRT782905	hsa-miR-4438	CLIP-seq
MIRT1931046	hsa-miR-4735-5p	CLIP-seq
MIRT1931047	hsa-miR-4775	CLIP-seq
MIRT1931048	hsa-miR-4794	CLIP-seq
MIRT782907	hsa-miR-5095	CLIP-seq
MIRT1931054	hsa-miR-590-3p	CLIP-seq
MIRT782910	hsa-miR-661	CLIP-seq
MIRT1931038	hsa-miR-1234	CLIP-seq
MIRT782893	hsa-miR-1254	CLIP-seq
MIRT782895	hsa-miR-129-5p	CLIP-seq
MIRT782898	hsa-miR-3116	CLIP-seq
MIRT2474692	hsa-miR-3149	CLIP-seq
MIRT782901	hsa-miR-4258	CLIP-seq
MIRT782904	hsa-miR-433	CLIP-seq
MIRT1931046	hsa-miR-4735-5p	CLIP-seq
MIRT1931047	hsa-miR-4775	CLIP-seq
MIRT1931048	hsa-miR-4794	CLIP-seq
MIRT1931054	hsa-miR-590-3p	CLIP-seq
MIRT782910	hsa-miR-661	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0006400	Process	TRNA modification	IEA
GO:0006400	Process	TRNA modification	ISS

Other IDs

• MIM: 618017
• HGNC: 23471
• e!Ensembl: ENSG00000134461

Protein

• UniProt ID: Q6P6B7
• Protein name: Ankyrin repeat domain-containing protein 16
• Protein function: Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12796	Ank_2	10 → 103	Ankyrin repeats (3 copies)	Repeat
  PF12796	Ank_2	141 → 236	Ankyrin repeats (3 copies)	Repeat
  PF13637	Ank_4	171 → 225		Repeat
  PF13637	Ank_4	274 → 327		Repeat

• Sequence:

  MAQPGDPRRLCRLVQEGRLRALKEELQAAGGCPGPAGDTLLHCAARHGHRDVLAYLAEAW
  GMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAAVDCLKKADWTPLMMACTRKNLGVI
  QELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKIRRTPLHTAAM
  HGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCGHIDVARLLLDEHGACLSAEDSLGA
  QALHRAAVTGQDEAIRFLVSELGVDVDVRATSTHLTALHYAAKEGHTSTIQTLLSLGADI
  NSKDEKNRSALHLACAGQHLACAKFLLQSGLKDSEDITGTLAQQLPRRADVLQGSGHSAM
  T

• Sequence length: 361