Gene Gene information from NCBI Gene database.
Entrez ID 54520
Gene name CCC complex scaffolding subunit CCDC93
Gene symbol CCDC93
Synonyms (NCBI Gene)
-
Chromosome 2
Chromosome location 2q14.1
miRNA miRNA information provided by mirtarbase database.
788
miRTarBase ID miRNA Experiments Reference
MIRT659728 hsa-miR-4280 HITS-CLIP 23824327
MIRT659727 hsa-miR-3168 HITS-CLIP 23824327
MIRT659726 hsa-miR-148b-5p HITS-CLIP 23824327
MIRT659725 hsa-miR-6874-3p HITS-CLIP 23824327
MIRT659724 hsa-miR-5584-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25355947, 26496610, 28514442, 28892079, 29778605, 30833792, 33961781, 35271311, 37172566
GO:0005768 Component Endosome IEA
GO:0005769 Component Early endosome IEA
GO:0006893 Process Golgi to plasma membrane transport IBA
GO:0006893 Process Golgi to plasma membrane transport IMP 25355947
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
620553 25611 ENSG00000125633
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q567U6
Protein name Coiled-coil domain-containing protein 93
Protein function Component of the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of composed of the CCC subcomplex and the retriever subcomplex (PubMed:37172566, PubMed:38459129). Component
PDB 8F2U , 8P0V , 8P0W , 8P0X
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF09762 CCDC93_CC 27 206 CCDC93, coiled-coil domain Coiled-coil
Sequence
MGLPRGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWC
ITTCNFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVV
QWLVKRAIETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRR
KYKRHQGAEELLDEESRIHATLLEYG
RRYGFSRQSKMEKAEDKKTALPAGLSATEKADAH
EEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSEL
SAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTY
SEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIEN
LKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAI
LHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLN
SIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLE
KQRLYFKTVKEFKEEGRKNEMLLSKVKAKAS
Sequence length 631
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
EBV-positive nodal T- and NK-cell lymphoma Likely benign rs1676940793 RCV004558105