Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	54491
Gene name Gene Name - the full gene name approved by the HGNC.	OTU deubiquitinase with linear linkage specificity like
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	OTULINL
Synonyms (NCBI Gene) Gene synonyms aliases	FAM105A, NET20
Chromosome Chromosome number	5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	5p15.2

Show/Hide all(13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005635	Component	Nuclear envelope	IDA	31056421
GO:0005635	Component	Nuclear envelope	IEA
GO:0005737	Component	Cytoplasm	IDA	31056421
GO:0005737	Component	Cytoplasm	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0016579	Process	Protein deubiquitination	IDA	31056421
GO:0019783	Function	Ubiquitin-like protein peptidase activity	IDA	31056421
GO:0043130	Function	Ubiquitin binding	IDA	31056421
GO:0098554	Component	Cytoplasmic side of endoplasmic reticulum membrane	IDA	31056421

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q9NUU6

Protein name

Inactive ubiquitin thioesterase OTULINL

Protein function

Lacks deubiquitinase activity.

PDB

6DRM

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16218	Peptidase_C101	88 → 355	Peptidase family C101	Family

Sequence

MAATRSPTRARERERSGAPAAGSDQVHSWMLATSQALDTVWRMAKGFVMLAVSFLVAAIC
YFRRLHLYSGHKLKWWIGYLQRKFKRNLSVEAEVDLLSYCAREWKGETPRNKLMRKAYEE
LFWRHHIKCVRQVRRDNYDALRSVLFQIFSQGISFPSWMKEKDIVKLPEKLLFSQGCNWI
QQYSFGPEKYTGSNVFGKLRKYVELLKTQWTEFNGIRDYHKRGSMCNTLFSDAILEYKLY
EALKFIMLYQVTEVYEQMKTKKVIPSLFRLLFSRETSSDPLSFMMNHLNSVGDTCGLEQI
DMFILGYSLEVKIKVFRLFKFNSRDFEVCYPEEPLRDWPEISLLTENDRHYHIPVF

Sequence length

356

Interactions

View interactions

Show/Hide Unknown Diseases (4)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Asthma	Nonatopic asthma, Atopic asthma, Asthma onset (childhood vs adult), Asthma in any disease, Asthma, Asthma (childhood onset)	N/A	N/A	GWAS
Dermatitis	Atopic dermatitis	N/A	N/A	GWAS
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Eczema	Eczema	N/A	N/A	GWAS

OTULINL (OTU deubiquitinase with linear linkage specificity like)