Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	54469
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger AN1-type containing 6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZFAND6
Synonyms (NCBI Gene) Gene synonyms aliases	AWP1, ZA20D3, ZFAND5B
Chromosome Chromosome number	15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	15q25.1

Show/Hide all(203)

miRTarBase ID	miRNA	Experiments	Reference
MIRT194174	hsa-miR-181a-5p	HITS-CLIP	21572407
MIRT194176	hsa-miR-181c-5p	HITS-CLIP	21572407
MIRT194177	hsa-miR-181d-5p	HITS-CLIP	21572407
MIRT194180	hsa-miR-4262	HITS-CLIP	21572407
MIRT194175	hsa-miR-181b-5p	HITS-CLIP	21572407
MIRT519890	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT194179	hsa-miR-580-5p	HITS-CLIP	21572407
MIRT282242	hsa-miR-935	HITS-CLIP	21572407
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	20371350
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	20371350
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	20371350
MIRT194180	hsa-miR-4262	PAR-CLIP	20371350
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	20371350
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	20371350
MIRT194179	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT282242	hsa-miR-935	PAR-CLIP	20371350
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	21572407
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	21572407
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	21572407
MIRT194180	hsa-miR-4262	PAR-CLIP	21572407
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	21572407
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT194179	hsa-miR-580-5p	PAR-CLIP	21572407
MIRT282242	hsa-miR-935	PAR-CLIP	21572407
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	23446348
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	23446348
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	23446348
MIRT194180	hsa-miR-4262	PAR-CLIP	23446348
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	23446348
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	23446348
MIRT194179	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT282242	hsa-miR-935	PAR-CLIP	23446348
MIRT194174	hsa-miR-181a-5p	HITS-CLIP	21572407
MIRT194176	hsa-miR-181c-5p	HITS-CLIP	21572407
MIRT194177	hsa-miR-181d-5p	HITS-CLIP	21572407
MIRT194180	hsa-miR-4262	HITS-CLIP	21572407
MIRT194175	hsa-miR-181b-5p	HITS-CLIP	21572407
MIRT519890	hsa-miR-4662a-3p	HITS-CLIP	21572407
MIRT194179	hsa-miR-580-5p	HITS-CLIP	21572407
MIRT282242	hsa-miR-935	HITS-CLIP	21572407
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	20371350
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	20371350
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	20371350
MIRT194180	hsa-miR-4262	PAR-CLIP	20371350
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	20371350
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	20371350
MIRT194179	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT282242	hsa-miR-935	PAR-CLIP	20371350
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	21572407
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	21572407
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	21572407
MIRT194180	hsa-miR-4262	PAR-CLIP	21572407
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	21572407
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT194179	hsa-miR-580-5p	PAR-CLIP	21572407
MIRT282242	hsa-miR-935	PAR-CLIP	21572407
MIRT194174	hsa-miR-181a-5p	PAR-CLIP	23446348
MIRT194176	hsa-miR-181c-5p	PAR-CLIP	23446348
MIRT194177	hsa-miR-181d-5p	PAR-CLIP	23446348
MIRT194180	hsa-miR-4262	PAR-CLIP	23446348
MIRT194175	hsa-miR-181b-5p	PAR-CLIP	23446348
MIRT519890	hsa-miR-4662a-3p	PAR-CLIP	23446348
MIRT194179	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT282242	hsa-miR-935	PAR-CLIP	23446348
MIRT1509695	hsa-miR-1264	CLIP-seq
MIRT1509696	hsa-miR-3157-5p	CLIP-seq
MIRT1509697	hsa-miR-4279	CLIP-seq
MIRT1509698	hsa-miR-4691-3p	CLIP-seq
MIRT1509699	hsa-miR-561	CLIP-seq
MIRT1509700	hsa-miR-1243	CLIP-seq
MIRT1509701	hsa-miR-155	CLIP-seq
MIRT1509702	hsa-miR-200b	CLIP-seq
MIRT1509703	hsa-miR-200c	CLIP-seq
MIRT1509704	hsa-miR-3120-3p	CLIP-seq
MIRT1509705	hsa-miR-3148	CLIP-seq
MIRT1509706	hsa-miR-3157-3p	CLIP-seq
MIRT1509707	hsa-miR-3654	CLIP-seq
MIRT1509708	hsa-miR-374c	CLIP-seq
MIRT1509709	hsa-miR-3908	CLIP-seq
MIRT1509710	hsa-miR-429	CLIP-seq
MIRT1509711	hsa-miR-4290	CLIP-seq
MIRT1509712	hsa-miR-4509	CLIP-seq
MIRT1509713	hsa-miR-4687-5p	CLIP-seq
MIRT1509714	hsa-miR-4766-5p	CLIP-seq
MIRT1509715	hsa-miR-4803	CLIP-seq
MIRT1509716	hsa-miR-548c-3p	CLIP-seq
MIRT1509717	hsa-miR-649	CLIP-seq
MIRT1509718	hsa-miR-655	CLIP-seq
MIRT1509719	hsa-miR-875-3p	CLIP-seq
MIRT1509720	hsa-miR-1279	CLIP-seq
MIRT1509721	hsa-miR-4789-5p	CLIP-seq
MIRT1509722	hsa-miR-568	CLIP-seq
MIRT1509723	hsa-miR-1305	CLIP-seq
MIRT1509724	hsa-miR-1323	CLIP-seq
MIRT1509725	hsa-miR-181a	CLIP-seq
MIRT1509726	hsa-miR-181b	CLIP-seq
MIRT1509727	hsa-miR-181c	CLIP-seq
MIRT1509728	hsa-miR-181d	CLIP-seq
MIRT1509729	hsa-miR-2467-3p	CLIP-seq
MIRT1509704	hsa-miR-3120-3p	CLIP-seq
MIRT1509706	hsa-miR-3157-3p	CLIP-seq
MIRT1509730	hsa-miR-3158-5p	CLIP-seq
MIRT1509731	hsa-miR-3678-3p	CLIP-seq
MIRT1509732	hsa-miR-3919	CLIP-seq
MIRT1509733	hsa-miR-4275	CLIP-seq
MIRT1509734	hsa-miR-4299	CLIP-seq
MIRT1509735	hsa-miR-4311	CLIP-seq
MIRT1509736	hsa-miR-4463	CLIP-seq
MIRT1509712	hsa-miR-4509	CLIP-seq
MIRT1509737	hsa-miR-4761-3p	CLIP-seq
MIRT1509715	hsa-miR-4803	CLIP-seq
MIRT1509738	hsa-miR-539	CLIP-seq
MIRT1509739	hsa-miR-548aa	CLIP-seq
MIRT1509740	hsa-miR-548o	CLIP-seq
MIRT1509741	hsa-miR-548u	CLIP-seq
MIRT1509742	hsa-miR-607	CLIP-seq
MIRT1509743	hsa-miR-1273d	CLIP-seq
MIRT1509720	hsa-miR-1279	CLIP-seq
MIRT1509744	hsa-miR-1324	CLIP-seq
MIRT1509745	hsa-miR-19a	CLIP-seq
MIRT1509746	hsa-miR-19b	CLIP-seq
MIRT1509704	hsa-miR-3120-3p	CLIP-seq
MIRT1509747	hsa-miR-3121-3p	CLIP-seq
MIRT1509748	hsa-miR-329	CLIP-seq
MIRT1509749	hsa-miR-362-3p	CLIP-seq
MIRT1509750	hsa-miR-3682-5p	CLIP-seq
MIRT1509751	hsa-miR-3941	CLIP-seq
MIRT1509752	hsa-miR-3942-3p	CLIP-seq
MIRT1509733	hsa-miR-4275	CLIP-seq
MIRT1509734	hsa-miR-4299	CLIP-seq
MIRT1509736	hsa-miR-4463	CLIP-seq
MIRT1509753	hsa-miR-4727-3p	CLIP-seq
MIRT1509721	hsa-miR-4789-5p	CLIP-seq
MIRT1509715	hsa-miR-4803	CLIP-seq
MIRT1509754	hsa-miR-518a-5p	CLIP-seq
MIRT1509755	hsa-miR-527	CLIP-seq
MIRT1509741	hsa-miR-548u	CLIP-seq
MIRT1509722	hsa-miR-568	CLIP-seq
MIRT1509756	hsa-miR-603	CLIP-seq
MIRT1509731	hsa-miR-3678-3p	CLIP-seq
MIRT1509750	hsa-miR-3682-5p	CLIP-seq
MIRT1509715	hsa-miR-4803	CLIP-seq
MIRT1509731	hsa-miR-3678-3p	CLIP-seq
MIRT1509700	hsa-miR-1243	CLIP-seq
MIRT1509701	hsa-miR-155	CLIP-seq
MIRT1509702	hsa-miR-200b	CLIP-seq
MIRT1509703	hsa-miR-200c	CLIP-seq
MIRT2666447	hsa-miR-203	CLIP-seq
MIRT2666448	hsa-miR-2276	CLIP-seq
MIRT1509729	hsa-miR-2467-3p	CLIP-seq
MIRT1509704	hsa-miR-3120-3p	CLIP-seq
MIRT1509705	hsa-miR-3148	CLIP-seq
MIRT1509706	hsa-miR-3157-3p	CLIP-seq
MIRT1509730	hsa-miR-3158-5p	CLIP-seq
MIRT1509707	hsa-miR-3654	CLIP-seq
MIRT1509731	hsa-miR-3678-3p	CLIP-seq
MIRT1509708	hsa-miR-374c	CLIP-seq
MIRT1509709	hsa-miR-3908	CLIP-seq
MIRT1509732	hsa-miR-3919	CLIP-seq
MIRT1509710	hsa-miR-429	CLIP-seq
MIRT1509711	hsa-miR-4290	CLIP-seq
MIRT1509735	hsa-miR-4311	CLIP-seq
MIRT1509712	hsa-miR-4509	CLIP-seq
MIRT1509713	hsa-miR-4687-5p	CLIP-seq
MIRT2666449	hsa-miR-4696	CLIP-seq
MIRT2666450	hsa-miR-4731-3p	CLIP-seq
MIRT1509737	hsa-miR-4761-3p	CLIP-seq
MIRT2666451	hsa-miR-4801	CLIP-seq
MIRT1509738	hsa-miR-539	CLIP-seq
MIRT1509716	hsa-miR-548c-3p	CLIP-seq
MIRT2666452	hsa-miR-548g	CLIP-seq
MIRT1509718	hsa-miR-655	CLIP-seq
MIRT1509719	hsa-miR-875-3p	CLIP-seq
MIRT1509700	hsa-miR-1243	CLIP-seq
MIRT1509701	hsa-miR-155	CLIP-seq
MIRT1509702	hsa-miR-200b	CLIP-seq
MIRT1509703	hsa-miR-200c	CLIP-seq
MIRT2666447	hsa-miR-203	CLIP-seq
MIRT2666448	hsa-miR-2276	CLIP-seq
MIRT1509729	hsa-miR-2467-3p	CLIP-seq
MIRT1509704	hsa-miR-3120-3p	CLIP-seq
MIRT1509705	hsa-miR-3148	CLIP-seq
MIRT1509706	hsa-miR-3157-3p	CLIP-seq
MIRT1509730	hsa-miR-3158-5p	CLIP-seq
MIRT1509707	hsa-miR-3654	CLIP-seq
MIRT1509731	hsa-miR-3678-3p	CLIP-seq
MIRT1509708	hsa-miR-374c	CLIP-seq
MIRT1509709	hsa-miR-3908	CLIP-seq
MIRT1509732	hsa-miR-3919	CLIP-seq
MIRT1509710	hsa-miR-429	CLIP-seq
MIRT1509711	hsa-miR-4290	CLIP-seq
MIRT1509735	hsa-miR-4311	CLIP-seq
MIRT1509712	hsa-miR-4509	CLIP-seq
MIRT1509713	hsa-miR-4687-5p	CLIP-seq
MIRT2666449	hsa-miR-4696	CLIP-seq
MIRT2666450	hsa-miR-4731-3p	CLIP-seq
MIRT1509737	hsa-miR-4761-3p	CLIP-seq
MIRT2666451	hsa-miR-4801	CLIP-seq
MIRT1509738	hsa-miR-539	CLIP-seq
MIRT1509716	hsa-miR-548c-3p	CLIP-seq
MIRT2666452	hsa-miR-548g	CLIP-seq
MIRT1509718	hsa-miR-655	CLIP-seq
MIRT1509719	hsa-miR-875-3p	CLIP-seq

Show/Hide all(17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 21810480, 25416956, 30561431, 32296183, 33961781
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006625	Process	Protein targeting to peroxisome	IBA
GO:0006625	Process	Protein targeting to peroxisome	IEA
GO:0006625	Process	Protein targeting to peroxisome	ISS
GO:0006915	Process	Apoptotic process	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0015031	Process	Protein transport	IEA
GO:0031593	Function	Polyubiquitin modification-dependent protein binding	IBA
GO:0031593	Function	Polyubiquitin modification-dependent protein binding	IEA
GO:0031593	Function	Polyubiquitin modification-dependent protein binding	ISS
GO:0043066	Process	Negative regulation of apoptotic process	IMP	21810480
GO:0043122	Process	Regulation of canonical NF-kappaB signal transduction	IMP	21810480
GO:0046872	Function	Metal ion binding	IEA
GO:0071356	Process	Cellular response to tumor necrosis factor	IMP	21810480

MIM	HGNC	e!Ensembl
610183	30164	ENSG00000086666

Protein

UniProt ID

Q6FIF0

Protein name

AN1-type zinc finger protein 6 (Associated with PRK1 protein) (Zinc finger A20 domain-containing protein 3)

Protein function

Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-depend

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01754	zf-A20	12 → 35	A20-like zinc finger	Family
PF01428	zf-AN1	149 → 186	AN1-like Zinc finger	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed with high level in heart, skeletal muscle, liver, kidney and placenta. {ECO:0000269|PubMed:11054541}.

Sequence

MAQETNHSQVPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPATSVSSLSE
SLPVQCTDGSVPEAQSALDSTSSSMQPSPVSNQSLLSESVASSQLDSTSVDKAVPETEDV
QASVSDTAQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGVHRYSDVHN
CSYNYKADAAEKIRKENPVVVGEKIQKI

Sequence length

208

Interactions

View interactions

	Reactome
			Peroxisomal protein import

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (8)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Diabetes Mellitus Type 2	Associate	25273842, 26599349, 37738238
Hypertension	Associate	26599349
Inflammation	Associate	36980809
Metabolic Syndrome	Associate	26599349
Myopia	Associate	36036911
Obesity	Associate	36980809
Obesity Abdominal	Associate	26599349
Prediabetic State	Associate	36980809

ZFAND6 (zinc finger AN1-type containing 6)