Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
54407
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier family 38 member 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLC38A2
Synonyms (NCBI Gene) Gene synonyms aliases
ATA2, PRO1068, SAT2, SNAT2
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q13.11
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT005160 hsa-miR-30a-5p pSILAC 18668040
MIRT017766 hsa-miR-335-5p Microarray 18185580
MIRT022556 hsa-miR-124-3p Microarray 18668037
MIRT027261 hsa-miR-101-3p Sequencing 20371350
MIRT005160 hsa-miR-30a-5p Proteomics;Other 18668040
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003333 Process Amino acid transmembrane transport IBA 21873635
GO:0003333 Process Amino acid transmembrane transport IMP 10930503
GO:0005295 Function Neutral amino acid:sodium symporter activity IDA 10930503
GO:0005515 Function Protein binding IPI 25759021, 32296183
GO:0005737 Component Cytoplasm IDA 15581851
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
605180 13448 ENSG00000134294
Protein
UniProt ID Q96QD8
Protein name Sodium-coupled neutral amino acid symporter 2 (Amino acid transporter A2) (Protein 40-9-1) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2)
Protein function Symporter that cotransports neutral amino acids and sodium ions from the extracellular to the intracellular side of the cell membrane (PubMed:10930503, PubMed:15774260, PubMed:15922329, PubMed:16621798). The transport is pH-sensitive, Li(+)-into
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01490 Aa_trans 69 495 Transmembrane amino acid transporter protein Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitously expressed (PubMed:10930503). Expressed in neocortex (PubMed:16616430). Widely expressed in the central nervous system with higher concentrations in caudal regions. Expressed by glutamatergic and GABAergic neurons together
Sequence
Sequence length 506
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Glutamatergic synapse
GABAergic synapse
Protein digestion and absorption
  Glutamate Neurotransmitter Release Cycle
Amino acid transport across the plasma membrane
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)
18400471
Associations from Text Mining
Disease Name Relationship Type References
Alzheimer Disease Associate 33875655
Bone Cysts Aneurysmal Associate 33147323
Breast Neoplasms Associate 33028955
Carcinogenesis Associate 36918802
Carcinoma Pancreatic Ductal Associate 32341021
Diabetes Mellitus Type 2 Associate 33989714
Fetal Diseases Associate 19741197
Fetal Growth Retardation Associate 26374858
Immune System Diseases Associate 37054944
Mitochondrial Diseases Associate 37210563