Gene Gene information from NCBI Gene database.
Entrez ID 53981
Gene name Cleavage and polyadenylation specific factor 2
Gene symbol CPSF2
Synonyms (NCBI Gene)
CPSF100
Chromosome 14
Chromosome location 14q32.12
miRNA miRNA information provided by mirtarbase database.
922
miRTarBase ID miRNA Experiments Reference
MIRT044892 hsa-miR-193a-3p CLASH 23622248
MIRT677316 hsa-miR-4519 HITS-CLIP 23824327
MIRT677315 hsa-miR-383-3p HITS-CLIP 23824327
MIRT677314 hsa-miR-3937 HITS-CLIP 23824327
MIRT677313 hsa-miR-5693 HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding IBA
GO:0003723 Function RNA binding IEA
GO:0005515 Function Protein binding IPI 18288197, 18688255, 26496610, 33961781, 35177536
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606028 2325 ENSG00000165934
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9P2I0
Protein name Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)
Protein function Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cl
PDB 6URG , 6V4X
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF16661 Lactamase_B_6 22 199 Metallo-beta-lactamase superfamily domain Domain
PF10996 Beta-Casp 243 368 Beta-Casp domain Domain
PF07521 RMMBL 528 591 Zn-dependent metallo-hydrolase RNA specificity domain Motif
PF13299 CPSF100_C 608 779 Cleavage and polyadenylation factor 2 C-terminal Family
Sequence
Sequence length 782
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  mRNA surveillance pathway   Transport of Mature mRNA Derived from an Intronless Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs