Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
53944
Gene name Gene Name - the full gene name approved by the HGNC.
Casein kinase 1 gamma 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CSNK1G1
Synonyms (NCBI Gene) Gene synonyms aliases
CK1gamma1
Chromosome Chromosome number
15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q22.31
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020171 hsa-miR-130b-3p Sequencing 20371350
MIRT028049 hsa-miR-93-5p Sequencing 20371350
MIRT028532 hsa-miR-30a-5p Proteomics 18668040
MIRT029209 hsa-miR-26b-5p Microarray 19088304
MIRT031148 hsa-miR-19b-3p Sequencing 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004674 Function Protein serine/threonine kinase activity IBA 21873635
GO:0004674 Function Protein serine/threonine kinase activity IDA 25500533
GO:0005515 Function Protein binding IPI 25416956
GO:0005524 Function ATP binding IEA
GO:0005634 Component Nucleus IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
606274 2454 ENSG00000169118
Protein
UniProt ID Q9HCP0
Protein name Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)
Protein function Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulat
PDB 2CMW
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00069 Pkinase 44 304 Protein kinase domain Domain
PF12605 CK1gamma_C 331 369 Casein kinase 1 gamma C terminal Family
PF12605 CK1gamma_C 367 392 Casein kinase 1 gamma C terminal Family
Sequence
Sequence length 422
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Hedgehog signaling pathway  
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Mental depression Major Depressive Disorder 29942085 ClinVar
Neurodevelopmental Disorders complex neurodevelopmental disorder GenCC
Neuroticism Neuroticism GWAS
Monoclonal Gammapathies Monoclonal Gammapathies GWAS
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Basal Cell Associate 29967001
Carcinoma Endometrioid Associate 29967001
Carcinoma Squamous Cell Associate 37248471
Lymphoma Non Hodgkin Associate 29967001
Optic atrophy X linked Associate 24463883