Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	53349
Gene name	Zinc finger FYVE-type containing 1
Gene symbol	ZFYVE1
Synonyms (NCBI Gene)	DFCP1PPP1R172SR3TAFF1ZNFN2A1
Chromosome	14
Chromosome location	14q24.2
Summary	The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to

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miRTarBase ID	miRNA	Experiments	Reference
MIRT018968	hsa-miR-335-5p	Microarray	18185580
MIRT046077	hsa-miR-125b-5p	CLASH	23622248
MIRT1512227	hsa-miR-1272	CLIP-seq
MIRT1512228	hsa-miR-1324	CLIP-seq
MIRT1512229	hsa-miR-145	CLIP-seq
MIRT1512230	hsa-miR-2115	CLIP-seq
MIRT1512231	hsa-miR-3065-3p	CLIP-seq
MIRT1512232	hsa-miR-3159	CLIP-seq
MIRT1512233	hsa-miR-3167	CLIP-seq
MIRT1512234	hsa-miR-3180-5p	CLIP-seq
MIRT1512235	hsa-miR-3188	CLIP-seq
MIRT1512236	hsa-miR-3682-3p	CLIP-seq
MIRT1512237	hsa-miR-4263	CLIP-seq
MIRT1512238	hsa-miR-4291	CLIP-seq
MIRT1512239	hsa-miR-452	CLIP-seq
MIRT1512240	hsa-miR-4676-3p	CLIP-seq
MIRT1512241	hsa-miR-4696	CLIP-seq
MIRT1512242	hsa-miR-4768-3p	CLIP-seq
MIRT1512243	hsa-miR-576-5p	CLIP-seq
MIRT1512244	hsa-miR-876-5p	CLIP-seq
MIRT1512245	hsa-miR-1827	CLIP-seq
MIRT1512246	hsa-miR-3612	CLIP-seq
MIRT1512247	hsa-miR-4459	CLIP-seq
MIRT1512248	hsa-miR-4695-5p	CLIP-seq
MIRT1512249	hsa-miR-4722-5p	CLIP-seq
MIRT1512250	hsa-miR-650	CLIP-seq
MIRT1512251	hsa-miR-665	CLIP-seq
MIRT1512252	hsa-miR-711	CLIP-seq
MIRT1512253	hsa-miR-765	CLIP-seq
MIRT1512254	hsa-miR-940	CLIP-seq
MIRT2154255	hsa-miR-4277	CLIP-seq
MIRT2154256	hsa-miR-4292	CLIP-seq
MIRT2154257	hsa-miR-4308	CLIP-seq
MIRT2154258	hsa-miR-433	CLIP-seq
MIRT2154259	hsa-miR-670	CLIP-seq
MIRT2154260	hsa-miR-1224-5p	CLIP-seq
MIRT1512245	hsa-miR-1827	CLIP-seq
MIRT2154261	hsa-miR-3150b-3p	CLIP-seq
MIRT2154262	hsa-miR-3184	CLIP-seq
MIRT1512246	hsa-miR-3612	CLIP-seq
MIRT2154263	hsa-miR-3689a-3p	CLIP-seq
MIRT2154264	hsa-miR-3689c	CLIP-seq
MIRT2154265	hsa-miR-3915	CLIP-seq
MIRT2154266	hsa-miR-423-5p	CLIP-seq
MIRT2154267	hsa-miR-4417	CLIP-seq
MIRT2154268	hsa-miR-4632	CLIP-seq
MIRT2154269	hsa-miR-4651	CLIP-seq
MIRT2154270	hsa-miR-4689	CLIP-seq
MIRT2154271	hsa-miR-4728-5p	CLIP-seq
MIRT2154272	hsa-miR-4784	CLIP-seq
MIRT2154273	hsa-miR-541	CLIP-seq
MIRT2154274	hsa-miR-608	CLIP-seq
MIRT1512250	hsa-miR-650	CLIP-seq
MIRT2154275	hsa-miR-654-5p	CLIP-seq
MIRT2374465	hsa-miR-15a	CLIP-seq
MIRT2374466	hsa-miR-15b	CLIP-seq
MIRT2374467	hsa-miR-16	CLIP-seq
MIRT2374468	hsa-miR-1914	CLIP-seq
MIRT2374469	hsa-miR-195	CLIP-seq
MIRT2374470	hsa-miR-424	CLIP-seq
MIRT2154267	hsa-miR-4417	CLIP-seq
MIRT2374471	hsa-miR-4476	CLIP-seq
MIRT2374472	hsa-miR-497	CLIP-seq
MIRT2154273	hsa-miR-541	CLIP-seq
MIRT2154275	hsa-miR-654-5p	CLIP-seq
MIRT2154261	hsa-miR-3150b-3p	CLIP-seq
MIRT2441791	hsa-miR-3155	CLIP-seq
MIRT2441792	hsa-miR-3155b	CLIP-seq
MIRT2154272	hsa-miR-4784	CLIP-seq
MIRT2441793	hsa-miR-484	CLIP-seq
MIRT2441791	hsa-miR-3155	CLIP-seq
MIRT2441792	hsa-miR-3155b	CLIP-seq
MIRT2466378	hsa-miR-4269	CLIP-seq
MIRT2374471	hsa-miR-4476	CLIP-seq
MIRT2466379	hsa-miR-4514	CLIP-seq
MIRT2466380	hsa-miR-4533	CLIP-seq
MIRT2466381	hsa-miR-4687-3p	CLIP-seq
MIRT2466382	hsa-miR-4692	CLIP-seq
MIRT2466383	hsa-miR-4742-5p	CLIP-seq
MIRT2441793	hsa-miR-484	CLIP-seq
MIRT1512254	hsa-miR-940	CLIP-seq
MIRT2667099	hsa-miR-10a	CLIP-seq
MIRT2667100	hsa-miR-10b	CLIP-seq
MIRT2154260	hsa-miR-1224-5p	CLIP-seq
MIRT2667101	hsa-miR-1228	CLIP-seq
MIRT2667102	hsa-miR-1264	CLIP-seq
MIRT2667103	hsa-miR-1302	CLIP-seq
MIRT2667104	hsa-miR-132	CLIP-seq
MIRT2667105	hsa-miR-1321	CLIP-seq
MIRT2667106	hsa-miR-1470	CLIP-seq
MIRT2667107	hsa-miR-147b	CLIP-seq
MIRT2667108	hsa-miR-149	CLIP-seq
MIRT2374465	hsa-miR-15a	CLIP-seq
MIRT2374466	hsa-miR-15b	CLIP-seq
MIRT2374467	hsa-miR-16	CLIP-seq
MIRT2374468	hsa-miR-1914	CLIP-seq
MIRT2667109	hsa-miR-1915	CLIP-seq
MIRT2374469	hsa-miR-195	CLIP-seq
MIRT2667110	hsa-miR-198	CLIP-seq
MIRT2667111	hsa-miR-204	CLIP-seq
MIRT2667112	hsa-miR-211	CLIP-seq
MIRT1512230	hsa-miR-2115	CLIP-seq
MIRT2667113	hsa-miR-212	CLIP-seq
MIRT2667114	hsa-miR-2278	CLIP-seq
MIRT2667115	hsa-miR-2355-5p	CLIP-seq
MIRT2667116	hsa-miR-2467-3p	CLIP-seq
MIRT2667117	hsa-miR-2467-5p	CLIP-seq
MIRT2667118	hsa-miR-27a	CLIP-seq
MIRT2667119	hsa-miR-27b	CLIP-seq
MIRT2667120	hsa-miR-2964a-5p	CLIP-seq
MIRT2667121	hsa-miR-3121-5p	CLIP-seq
MIRT2667122	hsa-miR-3122	CLIP-seq
MIRT2667123	hsa-miR-3125	CLIP-seq
MIRT2154261	hsa-miR-3150b-3p	CLIP-seq
MIRT2441791	hsa-miR-3155	CLIP-seq
MIRT2441792	hsa-miR-3155b	CLIP-seq
MIRT2667124	hsa-miR-3162-5p	CLIP-seq
MIRT2667125	hsa-miR-3179	CLIP-seq
MIRT2667126	hsa-miR-3187-3p	CLIP-seq
MIRT1512235	hsa-miR-3188	CLIP-seq
MIRT2667127	hsa-miR-3194-5p	CLIP-seq
MIRT2667128	hsa-miR-3199	CLIP-seq
MIRT2667129	hsa-miR-3202	CLIP-seq
MIRT2667130	hsa-miR-320a	CLIP-seq
MIRT2667131	hsa-miR-320b	CLIP-seq
MIRT2667132	hsa-miR-320c	CLIP-seq
MIRT2667133	hsa-miR-320d	CLIP-seq
MIRT2667134	hsa-miR-335	CLIP-seq
MIRT2667135	hsa-miR-3620	CLIP-seq
MIRT2667136	hsa-miR-3622b-5p	CLIP-seq
MIRT2667137	hsa-miR-3653	CLIP-seq
MIRT2667138	hsa-miR-3658	CLIP-seq
MIRT2667139	hsa-miR-3660	CLIP-seq
MIRT2667140	hsa-miR-3661	CLIP-seq
MIRT2667141	hsa-miR-3676	CLIP-seq
MIRT2667142	hsa-miR-3913-5p	CLIP-seq
MIRT2154265	hsa-miR-3915	CLIP-seq
MIRT2667143	hsa-miR-3916	CLIP-seq
MIRT2667144	hsa-miR-3924	CLIP-seq
MIRT2667145	hsa-miR-3938	CLIP-seq
MIRT2667146	hsa-miR-412	CLIP-seq
MIRT2374470	hsa-miR-424	CLIP-seq
MIRT2466378	hsa-miR-4269	CLIP-seq
MIRT2667147	hsa-miR-4270	CLIP-seq
MIRT2667148	hsa-miR-4284	CLIP-seq
MIRT2154256	hsa-miR-4292	CLIP-seq
MIRT2667149	hsa-miR-4298	CLIP-seq
MIRT2154257	hsa-miR-4308	CLIP-seq
MIRT2667150	hsa-miR-4311	CLIP-seq
MIRT2667151	hsa-miR-4328	CLIP-seq
MIRT2154258	hsa-miR-433	CLIP-seq
MIRT2667152	hsa-miR-4429	CLIP-seq
MIRT2667153	hsa-miR-4431	CLIP-seq
MIRT2667154	hsa-miR-4437	CLIP-seq
MIRT2667155	hsa-miR-4438	CLIP-seq
MIRT2667156	hsa-miR-4441	CLIP-seq
MIRT2667157	hsa-miR-4446-5p	CLIP-seq
MIRT2374471	hsa-miR-4476	CLIP-seq
MIRT2466379	hsa-miR-4514	CLIP-seq
MIRT2667158	hsa-miR-4526	CLIP-seq
MIRT2667159	hsa-miR-4528	CLIP-seq
MIRT2667160	hsa-miR-4529-5p	CLIP-seq
MIRT2667161	hsa-miR-4530	CLIP-seq
MIRT2466380	hsa-miR-4533	CLIP-seq
MIRT2667162	hsa-miR-4535	CLIP-seq
MIRT2667163	hsa-miR-4638-5p	CLIP-seq
MIRT2667164	hsa-miR-4640-5p	CLIP-seq
MIRT2667165	hsa-miR-4643	CLIP-seq
MIRT2667166	hsa-miR-4645-5p	CLIP-seq
MIRT2667167	hsa-miR-466	CLIP-seq
MIRT2667168	hsa-miR-4673	CLIP-seq
MIRT2667169	hsa-miR-4685-5p	CLIP-seq
MIRT2466381	hsa-miR-4687-3p	CLIP-seq
MIRT2154270	hsa-miR-4689	CLIP-seq
MIRT2667170	hsa-miR-4691-3p	CLIP-seq
MIRT2466382	hsa-miR-4692	CLIP-seq
MIRT2667171	hsa-miR-4699-5p	CLIP-seq
MIRT2667172	hsa-miR-4708-3p	CLIP-seq
MIRT2667173	hsa-miR-4712-3p	CLIP-seq
MIRT2667174	hsa-miR-4715-3p	CLIP-seq
MIRT2667175	hsa-miR-4720-3p	CLIP-seq
MIRT2667176	hsa-miR-4726-3p	CLIP-seq
MIRT2667177	hsa-miR-4726-5p	CLIP-seq
MIRT2667178	hsa-miR-4733-3p	CLIP-seq
MIRT2667179	hsa-miR-4739	CLIP-seq
MIRT2466383	hsa-miR-4742-5p	CLIP-seq
MIRT2667180	hsa-miR-4749-3p	CLIP-seq
MIRT2667181	hsa-miR-4753-3p	CLIP-seq
MIRT2667182	hsa-miR-4755-5p	CLIP-seq
MIRT2667183	hsa-miR-4756-3p	CLIP-seq
MIRT2667184	hsa-miR-4756-5p	CLIP-seq
MIRT1512242	hsa-miR-4768-3p	CLIP-seq
MIRT2154272	hsa-miR-4784	CLIP-seq
MIRT2667185	hsa-miR-4789-3p	CLIP-seq
MIRT2667186	hsa-miR-4789-5p	CLIP-seq
MIRT2667187	hsa-miR-4793-5p	CLIP-seq
MIRT2667188	hsa-miR-4802-5p	CLIP-seq
MIRT2667189	hsa-miR-483-3p	CLIP-seq
MIRT2441793	hsa-miR-484	CLIP-seq
MIRT2667190	hsa-miR-492	CLIP-seq
MIRT2374472	hsa-miR-497	CLIP-seq
MIRT2667191	hsa-miR-508-5p	CLIP-seq
MIRT2667192	hsa-miR-513a-3p	CLIP-seq
MIRT2667193	hsa-miR-513a-5p	CLIP-seq
MIRT2667194	hsa-miR-515-3p	CLIP-seq
MIRT2667195	hsa-miR-519e	CLIP-seq
MIRT2667196	hsa-miR-526b	CLIP-seq
MIRT2667197	hsa-miR-577	CLIP-seq
MIRT2667198	hsa-miR-603	CLIP-seq
MIRT2667199	hsa-miR-617	CLIP-seq
MIRT2667200	hsa-miR-623	CLIP-seq
MIRT2667201	hsa-miR-631	CLIP-seq
MIRT2667202	hsa-miR-658	CLIP-seq
MIRT2667203	hsa-miR-664	CLIP-seq
MIRT1512251	hsa-miR-665	CLIP-seq
MIRT2154259	hsa-miR-670	CLIP-seq
MIRT1512253	hsa-miR-765	CLIP-seq
MIRT2667204	hsa-miR-769-5p	CLIP-seq
MIRT2667205	hsa-miR-922	CLIP-seq
MIRT2667206	hsa-miR-935	CLIP-seq
MIRT1512254	hsa-miR-940	CLIP-seq
MIRT2667207	hsa-miR-942	CLIP-seq
MIRT2667099	hsa-miR-10a	CLIP-seq
MIRT2667100	hsa-miR-10b	CLIP-seq
MIRT2154260	hsa-miR-1224-5p	CLIP-seq
MIRT2667101	hsa-miR-1228	CLIP-seq
MIRT2667102	hsa-miR-1264	CLIP-seq
MIRT2667103	hsa-miR-1302	CLIP-seq
MIRT2667104	hsa-miR-132	CLIP-seq
MIRT2667105	hsa-miR-1321	CLIP-seq
MIRT2667106	hsa-miR-1470	CLIP-seq
MIRT2667107	hsa-miR-147b	CLIP-seq
MIRT2374465	hsa-miR-15a	CLIP-seq
MIRT2374466	hsa-miR-15b	CLIP-seq
MIRT2374467	hsa-miR-16	CLIP-seq
MIRT2374468	hsa-miR-1914	CLIP-seq
MIRT2667109	hsa-miR-1915	CLIP-seq
MIRT2374469	hsa-miR-195	CLIP-seq
MIRT2667110	hsa-miR-198	CLIP-seq
MIRT2667111	hsa-miR-204	CLIP-seq
MIRT2667112	hsa-miR-211	CLIP-seq
MIRT1512230	hsa-miR-2115	CLIP-seq
MIRT2667113	hsa-miR-212	CLIP-seq
MIRT2667114	hsa-miR-2278	CLIP-seq
MIRT2667115	hsa-miR-2355-5p	CLIP-seq
MIRT2667116	hsa-miR-2467-3p	CLIP-seq
MIRT2667117	hsa-miR-2467-5p	CLIP-seq
MIRT2667118	hsa-miR-27a	CLIP-seq
MIRT2667119	hsa-miR-27b	CLIP-seq
MIRT2667120	hsa-miR-2964a-5p	CLIP-seq
MIRT2667121	hsa-miR-3121-5p	CLIP-seq
MIRT2667122	hsa-miR-3122	CLIP-seq
MIRT2667123	hsa-miR-3125	CLIP-seq
MIRT2154261	hsa-miR-3150b-3p	CLIP-seq
MIRT2441791	hsa-miR-3155	CLIP-seq
MIRT2441792	hsa-miR-3155b	CLIP-seq
MIRT2667124	hsa-miR-3162-5p	CLIP-seq
MIRT2667125	hsa-miR-3179	CLIP-seq
MIRT1512235	hsa-miR-3188	CLIP-seq
MIRT2667127	hsa-miR-3194-5p	CLIP-seq
MIRT2667128	hsa-miR-3199	CLIP-seq
MIRT2667129	hsa-miR-3202	CLIP-seq
MIRT2667130	hsa-miR-320a	CLIP-seq
MIRT2667131	hsa-miR-320b	CLIP-seq
MIRT2667132	hsa-miR-320c	CLIP-seq
MIRT2667133	hsa-miR-320d	CLIP-seq
MIRT2667134	hsa-miR-335	CLIP-seq
MIRT2667135	hsa-miR-3620	CLIP-seq
MIRT2667136	hsa-miR-3622b-5p	CLIP-seq
MIRT2667137	hsa-miR-3653	CLIP-seq
MIRT2667138	hsa-miR-3658	CLIP-seq
MIRT2667142	hsa-miR-3913-5p	CLIP-seq
MIRT2154265	hsa-miR-3915	CLIP-seq
MIRT2667143	hsa-miR-3916	CLIP-seq
MIRT2667144	hsa-miR-3924	CLIP-seq
MIRT2667145	hsa-miR-3938	CLIP-seq
MIRT2667146	hsa-miR-412	CLIP-seq
MIRT2374470	hsa-miR-424	CLIP-seq
MIRT2466378	hsa-miR-4269	CLIP-seq
MIRT2667147	hsa-miR-4270	CLIP-seq
MIRT2667148	hsa-miR-4284	CLIP-seq
MIRT2154256	hsa-miR-4292	CLIP-seq
MIRT2667149	hsa-miR-4298	CLIP-seq
MIRT2154257	hsa-miR-4308	CLIP-seq
MIRT2667150	hsa-miR-4311	CLIP-seq
MIRT2667151	hsa-miR-4328	CLIP-seq
MIRT2154258	hsa-miR-433	CLIP-seq
MIRT2667152	hsa-miR-4429	CLIP-seq
MIRT2667153	hsa-miR-4431	CLIP-seq
MIRT2667154	hsa-miR-4437	CLIP-seq
MIRT2667155	hsa-miR-4438	CLIP-seq
MIRT2667156	hsa-miR-4441	CLIP-seq
MIRT2667157	hsa-miR-4446-5p	CLIP-seq
MIRT2374471	hsa-miR-4476	CLIP-seq
MIRT2466379	hsa-miR-4514	CLIP-seq
MIRT2667161	hsa-miR-4530	CLIP-seq
MIRT2466380	hsa-miR-4533	CLIP-seq
MIRT2667164	hsa-miR-4640-5p	CLIP-seq
MIRT2667165	hsa-miR-4643	CLIP-seq
MIRT2667166	hsa-miR-4645-5p	CLIP-seq
MIRT2667167	hsa-miR-466	CLIP-seq
MIRT2667168	hsa-miR-4673	CLIP-seq
MIRT2667169	hsa-miR-4685-5p	CLIP-seq
MIRT2466381	hsa-miR-4687-3p	CLIP-seq
MIRT2154270	hsa-miR-4689	CLIP-seq
MIRT2667170	hsa-miR-4691-3p	CLIP-seq
MIRT2466382	hsa-miR-4692	CLIP-seq
MIRT2667172	hsa-miR-4708-3p	CLIP-seq
MIRT2667173	hsa-miR-4712-3p	CLIP-seq
MIRT2667174	hsa-miR-4715-3p	CLIP-seq
MIRT2667175	hsa-miR-4720-3p	CLIP-seq
MIRT2667176	hsa-miR-4726-3p	CLIP-seq
MIRT2667177	hsa-miR-4726-5p	CLIP-seq
MIRT2667178	hsa-miR-4733-3p	CLIP-seq
MIRT2667179	hsa-miR-4739	CLIP-seq
MIRT2466383	hsa-miR-4742-5p	CLIP-seq
MIRT2667180	hsa-miR-4749-3p	CLIP-seq
MIRT2667181	hsa-miR-4753-3p	CLIP-seq
MIRT2667182	hsa-miR-4755-5p	CLIP-seq
MIRT2667183	hsa-miR-4756-3p	CLIP-seq
MIRT2667184	hsa-miR-4756-5p	CLIP-seq
MIRT1512242	hsa-miR-4768-3p	CLIP-seq
MIRT2154272	hsa-miR-4784	CLIP-seq
MIRT2667185	hsa-miR-4789-3p	CLIP-seq
MIRT2667186	hsa-miR-4789-5p	CLIP-seq
MIRT2667187	hsa-miR-4793-5p	CLIP-seq
MIRT2667188	hsa-miR-4802-5p	CLIP-seq
MIRT2667189	hsa-miR-483-3p	CLIP-seq
MIRT2441793	hsa-miR-484	CLIP-seq
MIRT2374472	hsa-miR-497	CLIP-seq
MIRT2667191	hsa-miR-508-5p	CLIP-seq
MIRT2667193	hsa-miR-513a-5p	CLIP-seq
MIRT2667194	hsa-miR-515-3p	CLIP-seq
MIRT2667195	hsa-miR-519e	CLIP-seq
MIRT2667196	hsa-miR-526b	CLIP-seq
MIRT2667197	hsa-miR-577	CLIP-seq
MIRT2667198	hsa-miR-603	CLIP-seq
MIRT2667199	hsa-miR-617	CLIP-seq
MIRT2667200	hsa-miR-623	CLIP-seq
MIRT2667202	hsa-miR-658	CLIP-seq
MIRT1512251	hsa-miR-665	CLIP-seq
MIRT2154259	hsa-miR-670	CLIP-seq
MIRT1512253	hsa-miR-765	CLIP-seq
MIRT2667204	hsa-miR-769-5p	CLIP-seq
MIRT2667205	hsa-miR-922	CLIP-seq
MIRT2667206	hsa-miR-935	CLIP-seq
MIRT1512254	hsa-miR-940	CLIP-seq
MIRT2667207	hsa-miR-942	CLIP-seq
MIRT2667140	hsa-miR-3661	CLIP-seq
MIRT2667201	hsa-miR-631	CLIP-seq

Show/Hide all (38)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000407	Component	Phagophore assembly site	IDA	23455425, 33499712
GO:0000407	Component	Phagophore assembly site	IEA
GO:0005515	Function	Protein binding	IPI	19389623, 30970241, 31293035, 32296183, 35551511
GO:0005545	Function	1-phosphatidylinositol binding	IBA
GO:0005545	Function	1-phosphatidylinositol binding	IDA	11256955
GO:0005547	Function	Phosphatidylinositol-3,4,5-trisphosphate binding	IBA
GO:0005547	Function	Phosphatidylinositol-3,4,5-trisphosphate binding	IDA	11804589
GO:0005739	Component	Mitochondrion	IDA	25876663
GO:0005739	Component	Mitochondrion	IEA
GO:0005776	Component	Autophagosome	IDA	22456507
GO:0005783	Component	Endoplasmic reticulum	IDA	11739631, 25876663
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	30970241
GO:0005794	Component	Golgi apparatus	IDA	25876663
GO:0005794	Component	Golgi apparatus	IEA
GO:0005795	Component	Golgi stack	IDA	11256955
GO:0005795	Component	Golgi stack	IEA
GO:0005811	Component	Lipid droplet	IBA
GO:0005811	Component	Lipid droplet	IDA	30970241, 31293035
GO:0005811	Component	Lipid droplet	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008270	Function	Zinc ion binding	NAS	11739631
GO:0009267	Process	Cellular response to starvation	IDA	25578879
GO:0016020	Component	Membrane	IDA	25578879
GO:0016236	Process	Macroautophagy	IDA	25578879
GO:0032266	Function	Phosphatidylinositol-3-phosphate binding	IBA
GO:0032266	Function	Phosphatidylinositol-3-phosphate binding	IDA	31293035
GO:0043325	Function	Phosphatidylinositol-3,4-bisphosphate binding	IBA
GO:0043325	Function	Phosphatidylinositol-3,4-bisphosphate binding	IDA	11804589
GO:0044233	Component	Mitochondria-associated endoplasmic reticulum membrane contact site	IDA	23455425
GO:0044829	Process	Host-mediated activation of viral genome replication	IDA	35551511
GO:0046872	Function	Metal ion binding	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	11739631
GO:0097629	Component	Extrinsic component of omegasome membrane	IDA	19898463
GO:0140042	Process	Lipid droplet formation	IBA
GO:0140042	Process	Lipid droplet formation	IEA
GO:0140042	Process	Lipid droplet formation	IMP	30970241
GO:1990462	Component	Omegasome	IDA	24954904, 25876663, 31293035

MIM	HGNC	e!Ensembl
605471	13180	ENSG00000165861

Q9HBF4

Protein name

Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1)

Protein function

Plays a role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (PubMed:30970241). Regulates the morphology, size and distribution of LDs (PubMed:30970241, PubMed:31293035). Mediat

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01363	FYVE	593 → 659	FYVE zinc finger	Domain
PF01363	FYVE	710 → 775	FYVE zinc finger	Domain

Tissue specificity

TISSUE SPECIFICITY: [Isoform 2]: Highly expressed in heart. Also detected in the testis. {ECO:0000269|PubMed:11024279, ECO:0000269|PubMed:11256955}.; TISSUE SPECIFICITY: [Isoform 1]: Expressed in all tissues examined, including, brain, placenta, lung, liv

Sequence

MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHER
IRLKPGHVPYCDLCKGLSGHLPGVRQRAIVRCQTCKINLCLECQKRTHSGGNKRRHPVTV
YNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLL
GATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTA
RCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSS
FFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGE
EVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIV
HVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQ
ILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNV
QLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILH
CHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL

Sequence length

777

Interactions

View interactions

	KEGG
	Autophagy - animal Pathways of neurodegeneration - multiple diseases

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (6)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
KIDNEY CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SEVERE ACUTE RESPIRATORY SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Autoimmune Diseases	Associate	34143178	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Abnormalities	Associate	34298938	★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart Diseases	Associate	23280630	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Associate	36830707	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZFYVE1 (zinc finger FYVE-type containing 1)