PLCL1 (phospholipase C like 1 (inactive))
| Gene | |
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
5334 |
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Phospholipase C like 1 (inactive) |
|
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
PLCL1 |
|
Synonyms (NCBI Gene)
Gene synonyms aliases
|
PLCE, PLCL, PLDL1, PPP1R127, PRIP |
|
Chromosome
Chromosome number
|
2 |
|
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
2q33.1 |
|
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
|||||||
| Protein | |||||||||||||||||||||||||||||||
| UniProt ID | Q15111 | ||||||||||||||||||||||||||||||
| Protein name | Inactive phospholipase C-like protein 1 (PLC-L1) (Phospholipase C-deleted in lung carcinoma) (Phospholipase C-related but catalytically inactive protein) (PRIP) | ||||||||||||||||||||||||||||||
| Protein function | Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By si | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
|
||||||||||||||||||||||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Expressed in a variety of fetal and adult organs including brain, lung and kidney. Its expression was greatly reduced in small and non-small cell lung carcinoma. Isoform 1 is predominantly expressed in brain. {ECO:0000269|PubMed:169524 | ||||||||||||||||||||||||||||||
| Sequence | |||||||||||||||||||||||||||||||
| Sequence length | 1095 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
||||||||
|
||||||||
|
Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||