Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
5306
Gene name Gene Name - the full gene name approved by the HGNC.
Phosphatidylinositol transfer protein alpha
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PITPNA
Synonyms (NCBI Gene) Gene synonyms aliases
HEL-S-36, PI-TPalpha, PITPN, VIB1A
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17p13.3
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidyl
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT049660 hsa-miR-92a-3p CLASH 23622248
MIRT043471 hsa-miR-331-3p CLASH 23622248
MIRT042415 hsa-miR-18b-5p CLASH 23622248
MIRT039821 hsa-miR-615-3p CLASH 23622248
MIRT039821 hsa-miR-615-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32814053
GO:0005634 Component Nucleus ISS
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005737 Component Cytoplasm ISS
GO:0005829 Component Cytosol TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
600174 9001 ENSG00000174238
Protein
UniProt ID Q00169
Protein name Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha)
Protein function Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes (PubMed:10531358, PubMed:14962392, PubMed:15522822, PubMed:18636990, PubMed:22822086). Shows a preference for PI and PC containing shorter saturat
PDB 1UW5 , 8PQO
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02121 IP_trans 2 252 Phosphatidylinositol transfer protein Family
Sequence
Sequence length 270
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Chronic obstructive pulmonary disease Chronic Obstructive Airway Disease 26503814 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Glycogen Storage Disease Type II Associate 20360305