Gene Gene information from NCBI Gene database.
Entrez ID 5306
Gene name Phosphatidylinositol transfer protein alpha
Gene symbol PITPNA
Synonyms (NCBI Gene)
HEL-S-36PI-TPalphaPITPNVIB1A
Chromosome 17
Chromosome location 17p13.3
Summary This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidyl
miRNA miRNA information provided by mirtarbase database.
912
miRTarBase ID miRNA Experiments Reference
MIRT049660 hsa-miR-92a-3p CLASH 23622248
MIRT043471 hsa-miR-331-3p CLASH 23622248
MIRT042415 hsa-miR-18b-5p CLASH 23622248
MIRT039821 hsa-miR-615-3p CLASH 23622248
MIRT039821 hsa-miR-615-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
39
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32814053
GO:0005548 Function Phospholipid transporter activity IEA
GO:0005634 Component Nucleus IEA
GO:0005634 Component Nucleus ISS
GO:0005737 Component Cytoplasm IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
600174 9001 ENSG00000174238
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q00169
Protein name Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha)
Protein function Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes (PubMed:10531358, PubMed:14962392, PubMed:15522822, PubMed:18636990, PubMed:22822086). Shows a preference for PI and PC containing shorter saturat
PDB 1UW5 , 8PQO
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02121 IP_trans 2 252 Phosphatidylinositol transfer protein Family
Sequence
Sequence length 270
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation