PIP (prolactin induced protein)

Gene
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
5304
Gene name Gene Name - the full gene name approved by the HGNC.
Prolactin induced protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PIP
Synonyms (NCBI Gene) Gene synonyms aliases
BRST-2, GCDFP-15, GCDFP15, GPIP4
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7q34
Transcription factors
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(2)
Transcription factor Regulation Reference
AR Unknown 21809344
RUNX2 Unknown 21809344
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(21)
GO ID Ontology Definition Evidence Reference
GO:0001580 Process Detection of chemical stimulus involved in sensory perception of bitter taste IDA 24248522
GO:0002682 Process Regulation of immune system process IBA
GO:0003779 Function Actin binding IEA
GO:0003779 Function Actin binding NAS 2013294
GO:0004190 Function Aspartic-type endopeptidase activity IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
176720 8993 ENSG00000159763
Protein
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID P12273
Protein name Prolactin-inducible protein (Gross cystic disease fluid protein 15) (GCDFP-15) (Prolactin-induced protein) (Secretory actin-binding protein) (SABP) (gp17)
PDB 3ES6
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05326 SVA 3 → 126 Seminal vesicle autoantigen (SVA) Family
Tissue specificity TISSUE SPECIFICITY: Expressed in pathological conditions of the mammary gland and in several exocrine tissues, such as the lacrimal, salivary, and sweat glands.
Sequence
Sequence length 146
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Miscellaneous transport and binding events
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Dermatomyositis Dermatomyositis N/A N/A GWAS
Show/Hide Text Mining Associations (35)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma Associate 26881627
Alzheimer Disease Associate 40471493
Aneuploidy Inhibit 24862759
Breast Neoplasms Associate 10504398, 10576657, 10713110, 18251583, 19262752, 20173733, 21411781, 22963676, 23755096, 24228128, 24862759, 25070172, 26711786, 30509049, 3667631
View all (4 more)
Breast Neoplasms Stimulate 23663520
Calcinosis Cutis Associate 17922593
Carcinoma Basal Cell Inhibit 21411781
Carcinoma Basal Cell Associate 28470571
Carcinoma in Situ Associate 28693610
Carcinoma Intraductal Noninfiltrating Associate 21286874