Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
53
Gene name Gene Name - the full gene name approved by the HGNC.
Acid phosphatase 2, lysosomal
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ACP2
Synonyms (NCBI Gene) Gene synonyms aliases
LAP
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11p11.2|11p12-p11
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from th
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001481 hsa-miR-16-5p pSILAC 18668040
MIRT023652 hsa-miR-1-3p Proteomics 18668040
MIRT028470 hsa-miR-30a-5p Proteomics 18668040
MIRT001481 hsa-miR-16-5p Proteomics;Other 18668040
MIRT763199 hsa-miR-1260 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003993 Function Acid phosphatase activity IBA 21873635
GO:0005515 Function Protein binding IPI 32814053
GO:0005764 Component Lysosome IBA 21873635
GO:0005764 Component Lysosome IDA 3160696
GO:0005765 Component Lysosomal membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
171650 123 ENSG00000134575
Protein
UniProt ID P11117
Protein name Lysosomal acid phosphatase (LAP) (EC 3.1.3.2)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00328 His_Phos_2 32 330 Histidine phosphatase superfamily (branch 2) Family
Sequence
Sequence length 423
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Riboflavin metabolism
Metabolic pathways
Lysosome
 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Acid Phosphatase Deficiency lysosomal acid phosphatase deficiency GenCC
Metabolic Syndrome Metabolic Syndrome GWAS
Insomnia Insomnia GWAS
Associations from Text Mining
Disease Name Relationship Type References
Anti N Methyl D Aspartate Receptor Encephalitis Associate 34584012
Carcinoma Hepatocellular Associate 15967798
Colorectal Neoplasms Associate 28076332
Drug Hypersensitivity Associate 25633562
Lysosomal Storage Diseases Associate 17357082
Neoplasms Associate 36706181
Supranuclear Palsy Progressive Associate 17357082