Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
53
Gene name Gene Name - the full gene name approved by the HGNC.
Acid phosphatase 2, lysosomal
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ACP2
Synonyms (NCBI Gene) Gene synonyms aliases
LAP
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11p11.2|11p12-p11
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from th
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001481 hsa-miR-16-5p pSILAC 18668040
MIRT023652 hsa-miR-1-3p Proteomics 18668040
MIRT028470 hsa-miR-30a-5p Proteomics 18668040
MIRT001481 hsa-miR-16-5p Proteomics;Other 18668040
MIRT763199 hsa-miR-1260 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001501 Process Skeletal system development IEA
GO:0003993 Function Acid phosphatase activity IBA
GO:0003993 Function Acid phosphatase activity IEA
GO:0003993 Function Acid phosphatase activity TAS 3191910
GO:0005515 Function Protein binding IPI 28514442, 32814053, 33961781
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
171650 123 ENSG00000134575
Protein
UniProt ID P11117
Protein name Lysosomal acid phosphatase (LAP) (EC 3.1.3.2)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00328 His_Phos_2 32 330 Histidine phosphatase superfamily (branch 2) Family
Sequence
Sequence length 423
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Riboflavin metabolism
Metabolic pathways
Lysosome
 
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Acid Phosphatase Deficiency lysosomal acid phosphatase deficiency N/A N/A GenCC
Insomnia Insomnia N/A N/A GWAS
Metabolic Syndrome Metabolic syndrome N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Anti N Methyl D Aspartate Receptor Encephalitis Associate 34584012
Carcinoma Hepatocellular Associate 15967798
Colorectal Neoplasms Associate 28076332
Drug Hypersensitivity Associate 25633562
Lysosomal Storage Diseases Associate 17357082
Neoplasms Associate 36706181
Supranuclear Palsy Progressive Associate 17357082