Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5298
Gene name	Phosphatidylinositol 4-kinase beta
Gene symbol	PI4KB
Synonyms (NCBI Gene)	DFNA87NPIKPI4K-BETAPI4K92PI4KBETAPI4KIIIPI4KIIIBETAPIK4CB
Chromosome	1
Chromosome location	1q21.3

358

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miRTarBase ID	miRNA	Experiments	Reference
MIRT021489	hsa-miR-191-5p	Sequencing	20371350
MIRT050695	hsa-miR-18a-5p	CLASH	23622248
MIRT046289	hsa-miR-23b-3p	CLASH	23622248
MIRT043436	hsa-miR-331-3p	CLASH	23622248
MIRT036853	hsa-miR-877-3p	CLASH	23622248
MIRT1232828	hsa-miR-103a	CLIP-seq
MIRT1232829	hsa-miR-107	CLIP-seq
MIRT1232830	hsa-miR-1193	CLIP-seq
MIRT1232831	hsa-miR-1225-5p	CLIP-seq
MIRT1232832	hsa-miR-1262	CLIP-seq
MIRT1232833	hsa-miR-1285	CLIP-seq
MIRT1232834	hsa-miR-1293	CLIP-seq
MIRT1232835	hsa-miR-1343	CLIP-seq
MIRT1232836	hsa-miR-140-3p	CLIP-seq
MIRT1232837	hsa-miR-15a	CLIP-seq
MIRT1232838	hsa-miR-15b	CLIP-seq
MIRT1232839	hsa-miR-16	CLIP-seq
MIRT1232840	hsa-miR-1909	CLIP-seq
MIRT1232841	hsa-miR-195	CLIP-seq
MIRT1232842	hsa-miR-3074-5p	CLIP-seq
MIRT1232843	hsa-miR-3132	CLIP-seq
MIRT1232844	hsa-miR-3165	CLIP-seq
MIRT1232845	hsa-miR-3170	CLIP-seq
MIRT1232846	hsa-miR-3187-5p	CLIP-seq
MIRT1232847	hsa-miR-3192	CLIP-seq
MIRT1232848	hsa-miR-3677-5p	CLIP-seq
MIRT1232849	hsa-miR-3689a-3p	CLIP-seq
MIRT1232850	hsa-miR-3689c	CLIP-seq
MIRT1232851	hsa-miR-3691-5p	CLIP-seq
MIRT1232852	hsa-miR-3918	CLIP-seq
MIRT1232853	hsa-miR-3926	CLIP-seq
MIRT1232854	hsa-miR-424	CLIP-seq
MIRT1232855	hsa-miR-4258	CLIP-seq
MIRT1232856	hsa-miR-4292	CLIP-seq
MIRT1232857	hsa-miR-4300	CLIP-seq
MIRT1232858	hsa-miR-4308	CLIP-seq
MIRT1232859	hsa-miR-4435	CLIP-seq
MIRT1232860	hsa-miR-4451	CLIP-seq
MIRT1232861	hsa-miR-4453	CLIP-seq
MIRT1232862	hsa-miR-4483	CLIP-seq
MIRT1232863	hsa-miR-4487	CLIP-seq
MIRT1232864	hsa-miR-4538	CLIP-seq
MIRT1232865	hsa-miR-4640-5p	CLIP-seq
MIRT1232866	hsa-miR-4701-3p	CLIP-seq
MIRT1232867	hsa-miR-4707-3p	CLIP-seq
MIRT1232868	hsa-miR-4726-5p	CLIP-seq
MIRT1232869	hsa-miR-4728-5p	CLIP-seq
MIRT1232870	hsa-miR-4732-5p	CLIP-seq
MIRT1232871	hsa-miR-4746-5p	CLIP-seq
MIRT1232872	hsa-miR-497	CLIP-seq
MIRT1232873	hsa-miR-519a	CLIP-seq
MIRT1232874	hsa-miR-519b-3p	CLIP-seq
MIRT1232875	hsa-miR-519c-3p	CLIP-seq
MIRT1232876	hsa-miR-545	CLIP-seq
MIRT1232877	hsa-miR-548s	CLIP-seq
MIRT1232878	hsa-miR-612	CLIP-seq
MIRT1232879	hsa-miR-635	CLIP-seq
MIRT1232880	hsa-miR-920	CLIP-seq
MIRT1232881	hsa-miR-939	CLIP-seq
MIRT1232882	hsa-miR-3133	CLIP-seq
MIRT1232883	hsa-miR-3921	CLIP-seq
MIRT1232884	hsa-miR-3978	CLIP-seq
MIRT1232885	hsa-miR-4251	CLIP-seq
MIRT1232886	hsa-miR-4329	CLIP-seq
MIRT1232887	hsa-miR-4428	CLIP-seq
MIRT1232888	hsa-miR-4434	CLIP-seq
MIRT1232889	hsa-miR-4516	CLIP-seq
MIRT1232890	hsa-miR-4653-5p	CLIP-seq
MIRT1232891	hsa-miR-548b-3p	CLIP-seq
MIRT1232892	hsa-miR-624	CLIP-seq
MIRT1232828	hsa-miR-103a	CLIP-seq
MIRT1232829	hsa-miR-107	CLIP-seq
MIRT1232830	hsa-miR-1193	CLIP-seq
MIRT2068394	hsa-miR-1207-3p	CLIP-seq
MIRT2068395	hsa-miR-1207-5p	CLIP-seq
MIRT2068396	hsa-miR-1224-3p	CLIP-seq
MIRT1232831	hsa-miR-1225-5p	CLIP-seq
MIRT2068397	hsa-miR-1260	CLIP-seq
MIRT2068398	hsa-miR-1260b	CLIP-seq
MIRT1232832	hsa-miR-1262	CLIP-seq
MIRT2068399	hsa-miR-1280	CLIP-seq
MIRT2068400	hsa-miR-1289	CLIP-seq
MIRT1232834	hsa-miR-1293	CLIP-seq
MIRT2068401	hsa-miR-1299	CLIP-seq
MIRT2068402	hsa-miR-1321	CLIP-seq
MIRT2068403	hsa-miR-1324	CLIP-seq
MIRT2068404	hsa-miR-134	CLIP-seq
MIRT1232835	hsa-miR-1343	CLIP-seq
MIRT1232836	hsa-miR-140-3p	CLIP-seq
MIRT2068405	hsa-miR-149	CLIP-seq
MIRT2068406	hsa-miR-150	CLIP-seq
MIRT1232837	hsa-miR-15a	CLIP-seq
MIRT1232838	hsa-miR-15b	CLIP-seq
MIRT1232839	hsa-miR-16	CLIP-seq
MIRT1232840	hsa-miR-1909	CLIP-seq
MIRT1232841	hsa-miR-195	CLIP-seq
MIRT2068407	hsa-miR-200b	CLIP-seq
MIRT2068408	hsa-miR-200c	CLIP-seq
MIRT2068409	hsa-miR-204	CLIP-seq
MIRT2068410	hsa-miR-211	CLIP-seq
MIRT2068411	hsa-miR-2110	CLIP-seq
MIRT1232842	hsa-miR-3074-5p	CLIP-seq
MIRT2068412	hsa-miR-3118	CLIP-seq
MIRT1232843	hsa-miR-3132	CLIP-seq
MIRT1232882	hsa-miR-3133	CLIP-seq
MIRT2068413	hsa-miR-3162-5p	CLIP-seq
MIRT2068414	hsa-miR-3164	CLIP-seq
MIRT1232844	hsa-miR-3165	CLIP-seq
MIRT1232845	hsa-miR-3170	CLIP-seq
MIRT2068415	hsa-miR-3174	CLIP-seq
MIRT2068416	hsa-miR-3183	CLIP-seq
MIRT2068417	hsa-miR-3184	CLIP-seq
MIRT2068418	hsa-miR-3189-3p	CLIP-seq
MIRT2068419	hsa-miR-3190	CLIP-seq
MIRT2068420	hsa-miR-3198	CLIP-seq
MIRT2068421	hsa-miR-323-5p	CLIP-seq
MIRT2068422	hsa-miR-34a	CLIP-seq
MIRT2068423	hsa-miR-34c-5p	CLIP-seq
MIRT2068424	hsa-miR-3616-3p	CLIP-seq
MIRT2068425	hsa-miR-3667-3p	CLIP-seq
MIRT2068426	hsa-miR-3676	CLIP-seq
MIRT1232848	hsa-miR-3677-5p	CLIP-seq
MIRT2068427	hsa-miR-3690	CLIP-seq
MIRT1232851	hsa-miR-3691-5p	CLIP-seq
MIRT2068428	hsa-miR-378	CLIP-seq
MIRT2068429	hsa-miR-378b	CLIP-seq
MIRT2068430	hsa-miR-378c	CLIP-seq
MIRT2068431	hsa-miR-378d	CLIP-seq
MIRT2068432	hsa-miR-378e	CLIP-seq
MIRT2068433	hsa-miR-378f	CLIP-seq
MIRT2068434	hsa-miR-378h	CLIP-seq
MIRT2068435	hsa-miR-378i	CLIP-seq
MIRT1232852	hsa-miR-3918	CLIP-seq
MIRT1232883	hsa-miR-3921	CLIP-seq
MIRT1232853	hsa-miR-3926	CLIP-seq
MIRT2068436	hsa-miR-3938	CLIP-seq
MIRT1232884	hsa-miR-3978	CLIP-seq
MIRT2068437	hsa-miR-422a	CLIP-seq
MIRT2068438	hsa-miR-423-5p	CLIP-seq
MIRT1232854	hsa-miR-424	CLIP-seq
MIRT1232885	hsa-miR-4251	CLIP-seq
MIRT2068439	hsa-miR-4254	CLIP-seq
MIRT1232855	hsa-miR-4258	CLIP-seq
MIRT2068440	hsa-miR-4260	CLIP-seq
MIRT2068441	hsa-miR-4271	CLIP-seq
MIRT2068442	hsa-miR-429	CLIP-seq
MIRT1232856	hsa-miR-4292	CLIP-seq
MIRT2068443	hsa-miR-4294	CLIP-seq
MIRT2068444	hsa-miR-4297	CLIP-seq
MIRT2068445	hsa-miR-4299	CLIP-seq
MIRT1232857	hsa-miR-4300	CLIP-seq
MIRT1232858	hsa-miR-4308	CLIP-seq
MIRT2068446	hsa-miR-4309	CLIP-seq
MIRT2068447	hsa-miR-4323	CLIP-seq
MIRT1232886	hsa-miR-4329	CLIP-seq
MIRT2068448	hsa-miR-4330	CLIP-seq
MIRT1232859	hsa-miR-4435	CLIP-seq
MIRT2068449	hsa-miR-4436b-3p	CLIP-seq
MIRT2068450	hsa-miR-4446-3p	CLIP-seq
MIRT2068451	hsa-miR-4446-5p	CLIP-seq
MIRT1232861	hsa-miR-4453	CLIP-seq
MIRT2068452	hsa-miR-4456	CLIP-seq
MIRT2068453	hsa-miR-4459	CLIP-seq
MIRT1232862	hsa-miR-4483	CLIP-seq
MIRT2068454	hsa-miR-449a	CLIP-seq
MIRT2068455	hsa-miR-449b	CLIP-seq
MIRT2068456	hsa-miR-4520a-3p	CLIP-seq
MIRT2068457	hsa-miR-4520b-3p	CLIP-seq
MIRT1232864	hsa-miR-4538	CLIP-seq
MIRT2068458	hsa-miR-4638-3p	CLIP-seq
MIRT1232865	hsa-miR-4640-5p	CLIP-seq
MIRT2068459	hsa-miR-4641	CLIP-seq
MIRT2068460	hsa-miR-4648	CLIP-seq
MIRT2068461	hsa-miR-4652-3p	CLIP-seq
MIRT1232890	hsa-miR-4653-5p	CLIP-seq
MIRT2068462	hsa-miR-4654	CLIP-seq
MIRT2068463	hsa-miR-4675	CLIP-seq
MIRT2068464	hsa-miR-4677-3p	CLIP-seq
MIRT2068465	hsa-miR-4679	CLIP-seq
MIRT2068466	hsa-miR-4688	CLIP-seq
MIRT1232866	hsa-miR-4701-3p	CLIP-seq
MIRT1232867	hsa-miR-4707-3p	CLIP-seq
MIRT2068467	hsa-miR-4713-5p	CLIP-seq
MIRT2068468	hsa-miR-4721	CLIP-seq
MIRT2068469	hsa-miR-4723-3p	CLIP-seq
MIRT2068470	hsa-miR-4725-3p	CLIP-seq
MIRT1232868	hsa-miR-4726-5p	CLIP-seq
MIRT1232869	hsa-miR-4728-5p	CLIP-seq
MIRT2068471	hsa-miR-4739	CLIP-seq
MIRT2068472	hsa-miR-4741	CLIP-seq
MIRT2068473	hsa-miR-4753-3p	CLIP-seq
MIRT2068474	hsa-miR-4755-5p	CLIP-seq
MIRT2068475	hsa-miR-4756-5p	CLIP-seq
MIRT2068476	hsa-miR-4757-5p	CLIP-seq
MIRT2068477	hsa-miR-4763-3p	CLIP-seq
MIRT2068478	hsa-miR-4769-5p	CLIP-seq
MIRT2068479	hsa-miR-4779	CLIP-seq
MIRT2068480	hsa-miR-4780	CLIP-seq
MIRT2068481	hsa-miR-4782-5p	CLIP-seq
MIRT2068482	hsa-miR-486-3p	CLIP-seq
MIRT1232872	hsa-miR-497	CLIP-seq
MIRT2068483	hsa-miR-502-5p	CLIP-seq
MIRT2068484	hsa-miR-516b	CLIP-seq
MIRT1232873	hsa-miR-519a	CLIP-seq
MIRT1232874	hsa-miR-519b-3p	CLIP-seq
MIRT1232875	hsa-miR-519c-3p	CLIP-seq
MIRT2068485	hsa-miR-532-3p	CLIP-seq
MIRT1232876	hsa-miR-545	CLIP-seq
MIRT1232891	hsa-miR-548b-3p	CLIP-seq
MIRT2068486	hsa-miR-548q	CLIP-seq
MIRT1232877	hsa-miR-548s	CLIP-seq
MIRT2068487	hsa-miR-578	CLIP-seq
MIRT2068488	hsa-miR-622	CLIP-seq
MIRT2068489	hsa-miR-623	CLIP-seq
MIRT1232879	hsa-miR-635	CLIP-seq
MIRT2068490	hsa-miR-642b	CLIP-seq
MIRT2068491	hsa-miR-665	CLIP-seq
MIRT2068492	hsa-miR-671-5p	CLIP-seq
MIRT2068493	hsa-miR-711	CLIP-seq
MIRT2068494	hsa-miR-760	CLIP-seq
MIRT2068495	hsa-miR-876-3p	CLIP-seq
MIRT1232880	hsa-miR-920	CLIP-seq
MIRT2068496	hsa-miR-935	CLIP-seq
MIRT1232881	hsa-miR-939	CLIP-seq
MIRT2068441	hsa-miR-4271	CLIP-seq
MIRT2068470	hsa-miR-4725-3p	CLIP-seq
MIRT1232830	hsa-miR-1193	CLIP-seq
MIRT2068394	hsa-miR-1207-3p	CLIP-seq
MIRT2068395	hsa-miR-1207-5p	CLIP-seq
MIRT2068396	hsa-miR-1224-3p	CLIP-seq
MIRT1232831	hsa-miR-1225-5p	CLIP-seq
MIRT2068397	hsa-miR-1260	CLIP-seq
MIRT2068398	hsa-miR-1260b	CLIP-seq
MIRT1232832	hsa-miR-1262	CLIP-seq
MIRT2068399	hsa-miR-1280	CLIP-seq
MIRT1232834	hsa-miR-1293	CLIP-seq
MIRT1232836	hsa-miR-140-3p	CLIP-seq
MIRT2068405	hsa-miR-149	CLIP-seq
MIRT2068406	hsa-miR-150	CLIP-seq
MIRT2068407	hsa-miR-200b	CLIP-seq
MIRT2068408	hsa-miR-200c	CLIP-seq
MIRT2068409	hsa-miR-204	CLIP-seq
MIRT2068410	hsa-miR-211	CLIP-seq
MIRT1232843	hsa-miR-3132	CLIP-seq
MIRT1232844	hsa-miR-3165	CLIP-seq
MIRT2068417	hsa-miR-3184	CLIP-seq
MIRT2068418	hsa-miR-3189-3p	CLIP-seq
MIRT2068421	hsa-miR-323-5p	CLIP-seq
MIRT2068426	hsa-miR-3676	CLIP-seq
MIRT1232851	hsa-miR-3691-5p	CLIP-seq
MIRT2068428	hsa-miR-378	CLIP-seq
MIRT2068429	hsa-miR-378b	CLIP-seq
MIRT2068430	hsa-miR-378c	CLIP-seq
MIRT2068431	hsa-miR-378d	CLIP-seq
MIRT2068432	hsa-miR-378e	CLIP-seq
MIRT2068433	hsa-miR-378f	CLIP-seq
MIRT2068434	hsa-miR-378h	CLIP-seq
MIRT2068435	hsa-miR-378i	CLIP-seq
MIRT2068437	hsa-miR-422a	CLIP-seq
MIRT2068438	hsa-miR-423-5p	CLIP-seq
MIRT2068442	hsa-miR-429	CLIP-seq
MIRT2068444	hsa-miR-4297	CLIP-seq
MIRT2068445	hsa-miR-4299	CLIP-seq
MIRT2068447	hsa-miR-4323	CLIP-seq
MIRT2068451	hsa-miR-4446-5p	CLIP-seq
MIRT2068452	hsa-miR-4456	CLIP-seq
MIRT2068453	hsa-miR-4459	CLIP-seq
MIRT1232862	hsa-miR-4483	CLIP-seq
MIRT2068458	hsa-miR-4638-3p	CLIP-seq
MIRT2068466	hsa-miR-4688	CLIP-seq
MIRT1232866	hsa-miR-4701-3p	CLIP-seq
MIRT2068467	hsa-miR-4713-5p	CLIP-seq
MIRT2068474	hsa-miR-4755-5p	CLIP-seq
MIRT2068477	hsa-miR-4763-3p	CLIP-seq
MIRT2068479	hsa-miR-4779	CLIP-seq
MIRT2068480	hsa-miR-4780	CLIP-seq
MIRT2068482	hsa-miR-486-3p	CLIP-seq
MIRT2068485	hsa-miR-532-3p	CLIP-seq
MIRT1232876	hsa-miR-545	CLIP-seq
MIRT2068486	hsa-miR-548q	CLIP-seq
MIRT2068487	hsa-miR-578	CLIP-seq
MIRT2068489	hsa-miR-623	CLIP-seq
MIRT2068490	hsa-miR-642b	CLIP-seq
MIRT2068491	hsa-miR-665	CLIP-seq
MIRT2068492	hsa-miR-671-5p	CLIP-seq
MIRT2068493	hsa-miR-711	CLIP-seq
MIRT2068494	hsa-miR-760	CLIP-seq
MIRT2068495	hsa-miR-876-3p	CLIP-seq
MIRT2068496	hsa-miR-935	CLIP-seq
MIRT1232830	hsa-miR-1193	CLIP-seq
MIRT2068394	hsa-miR-1207-3p	CLIP-seq
MIRT2068395	hsa-miR-1207-5p	CLIP-seq
MIRT2068396	hsa-miR-1224-3p	CLIP-seq
MIRT1232831	hsa-miR-1225-5p	CLIP-seq
MIRT2068397	hsa-miR-1260	CLIP-seq
MIRT2068398	hsa-miR-1260b	CLIP-seq
MIRT1232832	hsa-miR-1262	CLIP-seq
MIRT2068399	hsa-miR-1280	CLIP-seq
MIRT1232834	hsa-miR-1293	CLIP-seq
MIRT1232836	hsa-miR-140-3p	CLIP-seq
MIRT2068405	hsa-miR-149	CLIP-seq
MIRT2068406	hsa-miR-150	CLIP-seq
MIRT2068407	hsa-miR-200b	CLIP-seq
MIRT2068408	hsa-miR-200c	CLIP-seq
MIRT2068409	hsa-miR-204	CLIP-seq
MIRT2068410	hsa-miR-211	CLIP-seq
MIRT2687855	hsa-miR-3129-3p	CLIP-seq
MIRT1232843	hsa-miR-3132	CLIP-seq
MIRT1232844	hsa-miR-3165	CLIP-seq
MIRT1232845	hsa-miR-3170	CLIP-seq
MIRT2068417	hsa-miR-3184	CLIP-seq
MIRT2068418	hsa-miR-3189-3p	CLIP-seq
MIRT2068421	hsa-miR-323-5p	CLIP-seq
MIRT2068426	hsa-miR-3676	CLIP-seq
MIRT1232851	hsa-miR-3691-5p	CLIP-seq
MIRT2068428	hsa-miR-378	CLIP-seq
MIRT2068429	hsa-miR-378b	CLIP-seq
MIRT2068430	hsa-miR-378c	CLIP-seq
MIRT2068431	hsa-miR-378d	CLIP-seq
MIRT2068432	hsa-miR-378e	CLIP-seq
MIRT2068433	hsa-miR-378f	CLIP-seq
MIRT2068434	hsa-miR-378h	CLIP-seq
MIRT2068435	hsa-miR-378i	CLIP-seq
MIRT2068437	hsa-miR-422a	CLIP-seq
MIRT2068438	hsa-miR-423-5p	CLIP-seq
MIRT2068442	hsa-miR-429	CLIP-seq
MIRT2068444	hsa-miR-4297	CLIP-seq
MIRT2068445	hsa-miR-4299	CLIP-seq
MIRT2068447	hsa-miR-4323	CLIP-seq
MIRT2068451	hsa-miR-4446-5p	CLIP-seq
MIRT2068452	hsa-miR-4456	CLIP-seq
MIRT2068453	hsa-miR-4459	CLIP-seq
MIRT1232862	hsa-miR-4483	CLIP-seq
MIRT2687856	hsa-miR-4521	CLIP-seq
MIRT2068458	hsa-miR-4638-3p	CLIP-seq
MIRT2068466	hsa-miR-4688	CLIP-seq
MIRT1232866	hsa-miR-4701-3p	CLIP-seq
MIRT2068467	hsa-miR-4713-5p	CLIP-seq
MIRT2687857	hsa-miR-4731-3p	CLIP-seq
MIRT2068474	hsa-miR-4755-5p	CLIP-seq
MIRT2068477	hsa-miR-4763-3p	CLIP-seq
MIRT2068479	hsa-miR-4779	CLIP-seq
MIRT2068480	hsa-miR-4780	CLIP-seq
MIRT2687858	hsa-miR-4801	CLIP-seq
MIRT2068482	hsa-miR-486-3p	CLIP-seq
MIRT2068485	hsa-miR-532-3p	CLIP-seq
MIRT1232876	hsa-miR-545	CLIP-seq
MIRT2068486	hsa-miR-548q	CLIP-seq
MIRT2068487	hsa-miR-578	CLIP-seq
MIRT2687859	hsa-miR-607	CLIP-seq
MIRT2068489	hsa-miR-623	CLIP-seq
MIRT2068490	hsa-miR-642b	CLIP-seq
MIRT2068491	hsa-miR-665	CLIP-seq
MIRT2068492	hsa-miR-671-5p	CLIP-seq
MIRT2068493	hsa-miR-711	CLIP-seq
MIRT2068494	hsa-miR-760	CLIP-seq
MIRT2068495	hsa-miR-876-3p	CLIP-seq
MIRT2068496	hsa-miR-935	CLIP-seq

Show/Hide all (38)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IDA	27009356
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0000166	Function	Nucleotide binding	IEA
GO:0004430	Function	1-phosphatidylinositol 4-kinase activity	IBA
GO:0004430	Function	1-phosphatidylinositol 4-kinase activity	IDA	11277933, 27009356
GO:0004430	Function	1-phosphatidylinositol 4-kinase activity	IEA
GO:0004430	Function	1-phosphatidylinositol 4-kinase activity	TAS	9584208
GO:0005515	Function	Protein binding	IPI	16912074, 17088255, 22124328, 23572552, 24008843, 24876499, 27009356, 28514442, 33961781, 35271311, 36931259
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	TAS	9584208
GO:0005739	Component	Mitochondrion	IEA
GO:0005741	Component	Mitochondrial outer membrane	IEA
GO:0005768	Component	Endosome	TAS	9584208
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005794	Component	Golgi apparatus	IDA	25365221
GO:0005794	Component	Golgi apparatus	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006661	Process	Phosphatidylinositol biosynthetic process	TAS	9020160
GO:0006898	Process	Receptor-mediated endocytosis	TAS	9584208
GO:0007040	Process	Lysosome organization	IDA	25365221
GO:0007165	Process	Signal transduction	TAS	9020160
GO:0012505	Component	Endomembrane system	IEA
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030867	Component	Rough endoplasmic reticulum membrane	IEA
GO:0046854	Process	Phosphatidylinositol phosphate biosynthetic process	IBA
GO:0046854	Process	Phosphatidylinositol phosphate biosynthetic process	IEA
GO:0048015	Process	Phosphatidylinositol-mediated signaling	IBA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0048839	Process	Inner ear development	IBA
GO:0048839	Process	Inner ear development	IMP	33358777
GO:0071889	Function	14-3-3 protein binding	IDA	23572552

MIM	HGNC	e!Ensembl
602758	8984	ENSG00000143393

Q9UBF8

Protein name

Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92) (PI4KIII)

Protein function

Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation

PDB

2N73 , 4D0L , 4D0M , 4WAE , 4WAG , 5C46 , 5C4G , 5EUQ , 5FBL , 5FBQ , 5FBR , 5FBV , 5FBW , 5LX2 , 5NAS , 6GL3 , 8Q6F , 8Q6G , 8Q6H , 8VOF

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00454	PI3_PI4_kinase	559 → 763	Phosphatidylinositol 3- and 4-kinase	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver (PubMed:9020160, PubMed:9405935, PubMed:9405938). Expressed in the innear ear in the epithelium of the spinal organ o

Sequence

MGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVGELSVIDPEVAQKACQEVLEKVK
LLHGGVAVSSRGTPLELVNGDGVDSEIRCLDDPPAQIREEEDEMGAAVASGTAKGARRRR
QNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLL
NMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLI
LSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVEN
EDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLN
HKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPE
NRIRSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCD
NISQFSVDSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEK
VRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKI
LVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGY
CLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGG
LDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSM
TEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM

Sequence length

816

Interactions

View interactions

	KEGG		Reactome
	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system		Synthesis of PIPs at the Golgi membrane

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Hearing loss, autosomal dominant 87	Pathogenic	rs2528758305, rs2528620919, rs2528612732, rs765001640	RCV003152559 RCV003152560 RCV003152561 RCV003152562	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
DEAFNESS, AUTOSOMAL DOMINANT 87	—	Disgenet, HPO Disgenet, HPO	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PI4KB-related disorder	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SEVERE ACUTE RESPIRATORY SYNDROME	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (12)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	34155143	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	31759986	★★★★★ ★☆☆☆☆ Found in Text Mining only
Enterovirus Infections	Associate	38189249	★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastrointestinal Stromal Tumors	Associate	37616163	★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Associate	32187552	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Associate	30158316	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	18353764, 34155143	★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Associate	26213922	★★★★★ ★☆☆☆☆ Found in Text Mining only
Polycystic Kidney Diseases	Associate	34469896	★★★★★ ★☆☆☆☆ Found in Text Mining only
Polycythemia Vera	Associate	21177810	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Associate	18353764	★★★★★ ★☆☆☆☆ Found in Text Mining only
SeSAME syndrome	Associate	31640787	★★★★★ ★☆☆☆☆ Found in Text Mining only

PI4KB (phosphatidylinositol 4-kinase beta)