PIGR (polymeric immunoglobulin receptor)

Gene

• Entrez ID: 5284
• Gene name: Polymeric immunoglobulin receptor
• Gene symbol: PIGR
• Synonyms (NCBI Gene): -
• Chromosome: 1
• Chromosome location: 1q32.1
• Summary: This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical sur

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT713941	hsa-miR-504-5p	HITS-CLIP	19536157
MIRT713940	hsa-miR-3620-3p	HITS-CLIP	19536157
MIRT713939	hsa-miR-1224-3p	HITS-CLIP	19536157
MIRT713938	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT713937	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT713936	hsa-miR-877-3p	HITS-CLIP	19536157
MIRT713935	hsa-miR-150-5p	HITS-CLIP	19536157
MIRT713934	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT713933	hsa-miR-2116-3p	HITS-CLIP	19536157
MIRT713932	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT713931	hsa-miR-7152-3p	HITS-CLIP	19536157
MIRT713930	hsa-miR-4281	HITS-CLIP	19536157
MIRT713929	hsa-miR-1260a	HITS-CLIP	19536157
MIRT713928	hsa-miR-1260b	HITS-CLIP	19536157
MIRT713927	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT713926	hsa-miR-4713-5p	HITS-CLIP	19536157
MIRT713925	hsa-miR-133a-3p	HITS-CLIP	19536157
MIRT693581	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT693580	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT693579	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT693578	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT693577	hsa-miR-940	HITS-CLIP	23313552
MIRT693576	hsa-miR-3937	HITS-CLIP	23313552
MIRT693575	hsa-miR-1827	HITS-CLIP	23313552
MIRT693574	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT693573	hsa-miR-3612	HITS-CLIP	23313552
MIRT693572	hsa-miR-650	HITS-CLIP	23313552
MIRT693571	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT693570	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT693569	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT693568	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT693567	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT693566	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT693565	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT693564	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT693563	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT693562	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT693561	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT693560	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT693559	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT693558	hsa-miR-3689c	HITS-CLIP	23313552
MIRT693557	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT693556	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT693555	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT693554	hsa-miR-3122	HITS-CLIP	23313552
MIRT693553	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT693552	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT693551	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT629574	hsa-miR-583	HITS-CLIP	23824327
MIRT629573	hsa-miR-6089	HITS-CLIP	23824327
MIRT629572	hsa-miR-4743-5p	HITS-CLIP	23824327
MIRT629571	hsa-miR-4284	HITS-CLIP	23824327
MIRT629570	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT540325	hsa-miR-508-5p	PAR-CLIP	21572407
MIRT540324	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT540323	hsa-miR-939-3p	PAR-CLIP	21572407
MIRT540322	hsa-miR-766-3p	PAR-CLIP	21572407
MIRT540320	hsa-miR-4793-3p	PAR-CLIP	21572407
MIRT540321	hsa-miR-4486	PAR-CLIP	21572407
MIRT540319	hsa-miR-661	PAR-CLIP	21572407
MIRT540318	hsa-miR-1273a	PAR-CLIP	21572407
MIRT540317	hsa-miR-4649-5p	PAR-CLIP	21572407
MIRT540316	hsa-miR-6729-5p	PAR-CLIP	21572407
MIRT540315	hsa-miR-6512-3p	PAR-CLIP	21572407
MIRT540313	hsa-miR-6720-5p	PAR-CLIP	21572407
MIRT540314	hsa-miR-7703	PAR-CLIP	21572407
MIRT713941	hsa-miR-504-5p	HITS-CLIP	19536157
MIRT713940	hsa-miR-3620-3p	HITS-CLIP	19536157
MIRT713939	hsa-miR-1224-3p	HITS-CLIP	19536157
MIRT713938	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT713937	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT713936	hsa-miR-877-3p	HITS-CLIP	19536157
MIRT713935	hsa-miR-150-5p	HITS-CLIP	19536157
MIRT713934	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT713933	hsa-miR-2116-3p	HITS-CLIP	19536157
MIRT713932	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT713931	hsa-miR-7152-3p	HITS-CLIP	19536157
MIRT713930	hsa-miR-4281	HITS-CLIP	19536157
MIRT713929	hsa-miR-1260a	HITS-CLIP	19536157
MIRT713928	hsa-miR-1260b	HITS-CLIP	19536157
MIRT713927	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT713926	hsa-miR-4713-5p	HITS-CLIP	19536157
MIRT713925	hsa-miR-133a-3p	HITS-CLIP	19536157
MIRT693581	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT693580	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT693579	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT693578	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT693577	hsa-miR-940	HITS-CLIP	23313552
MIRT693576	hsa-miR-3937	HITS-CLIP	23313552
MIRT693575	hsa-miR-1827	HITS-CLIP	23313552
MIRT693574	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT693573	hsa-miR-3612	HITS-CLIP	23313552
MIRT693572	hsa-miR-650	HITS-CLIP	23313552
MIRT693571	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT693570	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT693569	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT693568	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT693567	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT693566	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT693565	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT693564	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT693563	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT693562	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT693561	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT693560	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT693559	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT693558	hsa-miR-3689c	HITS-CLIP	23313552
MIRT693557	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT693556	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT693555	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT693554	hsa-miR-3122	HITS-CLIP	23313552
MIRT693553	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT693552	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT693551	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT629574	hsa-miR-583	HITS-CLIP	23824327
MIRT629573	hsa-miR-6089	HITS-CLIP	23824327
MIRT629572	hsa-miR-4743-5p	HITS-CLIP	23824327
MIRT629571	hsa-miR-4284	HITS-CLIP	23824327
MIRT629570	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT540325	hsa-miR-508-5p	PAR-CLIP	21572407
MIRT540324	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT540323	hsa-miR-939-3p	PAR-CLIP	21572407
MIRT540322	hsa-miR-766-3p	PAR-CLIP	21572407
MIRT540320	hsa-miR-4793-3p	PAR-CLIP	21572407
MIRT540321	hsa-miR-4486	PAR-CLIP	21572407
MIRT540319	hsa-miR-661	PAR-CLIP	21572407
MIRT540318	hsa-miR-1273a	PAR-CLIP	21572407
MIRT540317	hsa-miR-4649-5p	PAR-CLIP	21572407
MIRT540316	hsa-miR-6729-5p	PAR-CLIP	21572407
MIRT540315	hsa-miR-6512-3p	PAR-CLIP	21572407
MIRT540313	hsa-miR-6720-5p	PAR-CLIP	21572407
MIRT540314	hsa-miR-7703	PAR-CLIP	21572407
MIRT1233469	hsa-miR-10a	CLIP-seq
MIRT1233470	hsa-miR-10b	CLIP-seq
MIRT1233471	hsa-miR-1207-5p	CLIP-seq
MIRT1233472	hsa-miR-1273	CLIP-seq
MIRT1233473	hsa-miR-1283	CLIP-seq
MIRT1233474	hsa-miR-2114	CLIP-seq
MIRT1233475	hsa-miR-24	CLIP-seq
MIRT1233476	hsa-miR-3137	CLIP-seq
MIRT1233477	hsa-miR-3140-5p	CLIP-seq
MIRT1233478	hsa-miR-3187-3p	CLIP-seq
MIRT1233479	hsa-miR-3192	CLIP-seq
MIRT1233480	hsa-miR-330-3p	CLIP-seq
MIRT1233481	hsa-miR-339-5p	CLIP-seq
MIRT1233482	hsa-miR-3613-3p	CLIP-seq
MIRT1233483	hsa-miR-3622a-3p	CLIP-seq
MIRT1233484	hsa-miR-3622b-3p	CLIP-seq
MIRT1233485	hsa-miR-3929	CLIP-seq
MIRT1233486	hsa-miR-4252	CLIP-seq
MIRT1233487	hsa-miR-4316	CLIP-seq
MIRT1233488	hsa-miR-4419b	CLIP-seq
MIRT1233489	hsa-miR-4421	CLIP-seq
MIRT1233490	hsa-miR-4433	CLIP-seq
MIRT1233491	hsa-miR-4435	CLIP-seq
MIRT1233492	hsa-miR-4452	CLIP-seq
MIRT1233493	hsa-miR-4453	CLIP-seq
MIRT1233494	hsa-miR-4459	CLIP-seq
MIRT1233495	hsa-miR-4478	CLIP-seq
MIRT1233496	hsa-miR-4529-5p	CLIP-seq
MIRT1233497	hsa-miR-4537	CLIP-seq
MIRT1233498	hsa-miR-4538	CLIP-seq
MIRT1233499	hsa-miR-4649-3p	CLIP-seq
MIRT1233500	hsa-miR-4680-3p	CLIP-seq
MIRT1233501	hsa-miR-4683	CLIP-seq
MIRT1233502	hsa-miR-4684-5p	CLIP-seq
MIRT1233503	hsa-miR-4701-5p	CLIP-seq
MIRT1233504	hsa-miR-4710	CLIP-seq
MIRT1233505	hsa-miR-4722-5p	CLIP-seq
MIRT1233506	hsa-miR-4736	CLIP-seq
MIRT1233507	hsa-miR-4763-3p	CLIP-seq
MIRT1233508	hsa-miR-4768-3p	CLIP-seq
MIRT1233509	hsa-miR-4786-5p	CLIP-seq
MIRT1233510	hsa-miR-4790-3p	CLIP-seq
MIRT1233511	hsa-miR-4793-5p	CLIP-seq
MIRT1233512	hsa-miR-4794	CLIP-seq
MIRT1233513	hsa-miR-485-5p	CLIP-seq
MIRT1233514	hsa-miR-490-3p	CLIP-seq
MIRT1233515	hsa-miR-505	CLIP-seq
MIRT1233516	hsa-miR-548p	CLIP-seq
MIRT1233517	hsa-miR-548s	CLIP-seq
MIRT1233518	hsa-miR-566	CLIP-seq
MIRT1233519	hsa-miR-580	CLIP-seq
MIRT1233520	hsa-miR-588	CLIP-seq
MIRT1233521	hsa-miR-593	CLIP-seq
MIRT1233522	hsa-miR-635	CLIP-seq
MIRT1233523	hsa-miR-658	CLIP-seq
MIRT1233524	hsa-miR-766	CLIP-seq
MIRT1233525	hsa-miR-890	CLIP-seq
MIRT1233486	hsa-miR-4252	CLIP-seq
MIRT1233497	hsa-miR-4537	CLIP-seq
MIRT1233523	hsa-miR-658	CLIP-seq
MIRT2068695	hsa-miR-1262	CLIP-seq
MIRT1233472	hsa-miR-1273	CLIP-seq
MIRT2068696	hsa-miR-128	CLIP-seq
MIRT2068697	hsa-miR-145	CLIP-seq
MIRT1233474	hsa-miR-2114	CLIP-seq
MIRT2068698	hsa-miR-217	CLIP-seq
MIRT2068699	hsa-miR-2355-5p	CLIP-seq
MIRT2068700	hsa-miR-28-5p	CLIP-seq
MIRT1233476	hsa-miR-3137	CLIP-seq
MIRT2068701	hsa-miR-3139	CLIP-seq
MIRT2068702	hsa-miR-3160-3p	CLIP-seq
MIRT2068703	hsa-miR-3672	CLIP-seq
MIRT1233485	hsa-miR-3929	CLIP-seq
MIRT1233486	hsa-miR-4252	CLIP-seq
MIRT2068704	hsa-miR-4270	CLIP-seq
MIRT1233488	hsa-miR-4419b	CLIP-seq
MIRT2068705	hsa-miR-4441	CLIP-seq
MIRT1233495	hsa-miR-4478	CLIP-seq
MIRT2068706	hsa-miR-4481	CLIP-seq
MIRT1233497	hsa-miR-4537	CLIP-seq
MIRT1233499	hsa-miR-4649-3p	CLIP-seq
MIRT2068707	hsa-miR-4701-3p	CLIP-seq
MIRT2068708	hsa-miR-4745-5p	CLIP-seq
MIRT1233513	hsa-miR-485-5p	CLIP-seq
MIRT2068709	hsa-miR-615-5p	CLIP-seq
MIRT2068710	hsa-miR-622	CLIP-seq
MIRT2068711	hsa-miR-642b	CLIP-seq
MIRT1233523	hsa-miR-658	CLIP-seq
MIRT2068712	hsa-miR-665	CLIP-seq
MIRT2068713	hsa-miR-708	CLIP-seq
MIRT1233524	hsa-miR-766	CLIP-seq
MIRT1233472	hsa-miR-1273	CLIP-seq
MIRT1233474	hsa-miR-2114	CLIP-seq
MIRT1233475	hsa-miR-24	CLIP-seq
MIRT2295806	hsa-miR-3128	CLIP-seq
MIRT2295807	hsa-miR-3136-3p	CLIP-seq
MIRT1233476	hsa-miR-3137	CLIP-seq
MIRT2295808	hsa-miR-3183	CLIP-seq
MIRT1233479	hsa-miR-3192	CLIP-seq
MIRT2295809	hsa-miR-326	CLIP-seq
MIRT2295810	hsa-miR-330-5p	CLIP-seq
MIRT1233485	hsa-miR-3929	CLIP-seq
MIRT1233486	hsa-miR-4252	CLIP-seq
MIRT1233487	hsa-miR-4316	CLIP-seq
MIRT1233488	hsa-miR-4419b	CLIP-seq
MIRT1233490	hsa-miR-4433	CLIP-seq
MIRT1233494	hsa-miR-4459	CLIP-seq
MIRT1233495	hsa-miR-4478	CLIP-seq
MIRT1233497	hsa-miR-4537	CLIP-seq
MIRT1233501	hsa-miR-4683	CLIP-seq
MIRT1233504	hsa-miR-4710	CLIP-seq
MIRT2295811	hsa-miR-4720-5p	CLIP-seq
MIRT2295812	hsa-miR-4723-3p	CLIP-seq
MIRT2295813	hsa-miR-4749-3p	CLIP-seq
MIRT1233508	hsa-miR-4768-3p	CLIP-seq
MIRT1233509	hsa-miR-4786-5p	CLIP-seq
MIRT1233511	hsa-miR-4793-5p	CLIP-seq
MIRT1233512	hsa-miR-4794	CLIP-seq
MIRT2295814	hsa-miR-4799-3p	CLIP-seq
MIRT1233513	hsa-miR-485-5p	CLIP-seq
MIRT1233523	hsa-miR-658	CLIP-seq
MIRT1233524	hsa-miR-766	CLIP-seq
MIRT2295815	hsa-miR-767-5p	CLIP-seq
MIRT1233525	hsa-miR-890	CLIP-seq
MIRT1233474	hsa-miR-2114	CLIP-seq
MIRT2295807	hsa-miR-3136-3p	CLIP-seq
MIRT1233476	hsa-miR-3137	CLIP-seq
MIRT1233469	hsa-miR-10a	CLIP-seq
MIRT1233470	hsa-miR-10b	CLIP-seq
MIRT2068695	hsa-miR-1262	CLIP-seq
MIRT2456470	hsa-miR-1299	CLIP-seq
MIRT2068697	hsa-miR-145	CLIP-seq
MIRT2456471	hsa-miR-185	CLIP-seq
MIRT2068698	hsa-miR-217	CLIP-seq
MIRT2456472	hsa-miR-2278	CLIP-seq
MIRT2456473	hsa-miR-3160-5p	CLIP-seq
MIRT2295808	hsa-miR-3183	CLIP-seq
MIRT1233481	hsa-miR-339-5p	CLIP-seq
MIRT1233482	hsa-miR-3613-3p	CLIP-seq
MIRT2456474	hsa-miR-371-5p	CLIP-seq
MIRT2456475	hsa-miR-371b-5p	CLIP-seq
MIRT2456476	hsa-miR-4306	CLIP-seq
MIRT1233489	hsa-miR-4421	CLIP-seq
MIRT2456477	hsa-miR-4644	CLIP-seq
MIRT2456478	hsa-miR-4662a-5p	CLIP-seq
MIRT2456479	hsa-miR-4676-5p	CLIP-seq
MIRT1233502	hsa-miR-4684-5p	CLIP-seq
MIRT2068707	hsa-miR-4701-3p	CLIP-seq
MIRT2295812	hsa-miR-4723-3p	CLIP-seq
MIRT2295813	hsa-miR-4749-3p	CLIP-seq
MIRT2456480	hsa-miR-4755-3p	CLIP-seq
MIRT2456481	hsa-miR-4782-5p	CLIP-seq
MIRT2456482	hsa-miR-516b	CLIP-seq
MIRT2456483	hsa-miR-548c-3p	CLIP-seq
MIRT2456484	hsa-miR-575	CLIP-seq
MIRT1233521	hsa-miR-593	CLIP-seq
MIRT2068710	hsa-miR-622	CLIP-seq
MIRT2456485	hsa-miR-668	CLIP-seq
MIRT1233469	hsa-miR-10a	CLIP-seq
MIRT1233470	hsa-miR-10b	CLIP-seq
MIRT1233481	hsa-miR-339-5p	CLIP-seq
MIRT1233482	hsa-miR-3613-3p	CLIP-seq
MIRT1233489	hsa-miR-4421	CLIP-seq
MIRT2456478	hsa-miR-4662a-5p	CLIP-seq
MIRT2456479	hsa-miR-4676-5p	CLIP-seq
MIRT1233502	hsa-miR-4684-5p	CLIP-seq
MIRT2456480	hsa-miR-4755-3p	CLIP-seq
MIRT2456483	hsa-miR-548c-3p	CLIP-seq
MIRT2456484	hsa-miR-575	CLIP-seq
MIRT1233521	hsa-miR-593	CLIP-seq
MIRT1233469	hsa-miR-10a	CLIP-seq
MIRT1233470	hsa-miR-10b	CLIP-seq
MIRT2068696	hsa-miR-128	CLIP-seq
MIRT1233473	hsa-miR-1283	CLIP-seq
MIRT1233481	hsa-miR-339-5p	CLIP-seq
MIRT1233482	hsa-miR-3613-3p	CLIP-seq
MIRT2068703	hsa-miR-3672	CLIP-seq
MIRT2456474	hsa-miR-371-5p	CLIP-seq
MIRT2456475	hsa-miR-371b-5p	CLIP-seq
MIRT1233489	hsa-miR-4421	CLIP-seq
MIRT1233490	hsa-miR-4433	CLIP-seq
MIRT1233494	hsa-miR-4459	CLIP-seq
MIRT2456478	hsa-miR-4662a-5p	CLIP-seq
MIRT2456479	hsa-miR-4676-5p	CLIP-seq
MIRT1233501	hsa-miR-4683	CLIP-seq
MIRT1233502	hsa-miR-4684-5p	CLIP-seq
MIRT2456480	hsa-miR-4755-3p	CLIP-seq
MIRT1233508	hsa-miR-4768-3p	CLIP-seq
MIRT1233509	hsa-miR-4786-5p	CLIP-seq
MIRT1233511	hsa-miR-4793-5p	CLIP-seq
MIRT1233512	hsa-miR-4794	CLIP-seq
MIRT2456483	hsa-miR-548c-3p	CLIP-seq
MIRT2456484	hsa-miR-575	CLIP-seq
MIRT1233521	hsa-miR-593	CLIP-seq
MIRT2068711	hsa-miR-642b	CLIP-seq
MIRT1233469	hsa-miR-10a	CLIP-seq
MIRT1233470	hsa-miR-10b	CLIP-seq
MIRT1233471	hsa-miR-1207-5p	CLIP-seq
MIRT1233473	hsa-miR-1283	CLIP-seq
MIRT1233481	hsa-miR-339-5p	CLIP-seq
MIRT1233482	hsa-miR-3613-3p	CLIP-seq
MIRT2068703	hsa-miR-3672	CLIP-seq
MIRT2456474	hsa-miR-371-5p	CLIP-seq
MIRT2456475	hsa-miR-371b-5p	CLIP-seq
MIRT2687874	hsa-miR-374a	CLIP-seq
MIRT2687875	hsa-miR-374b	CLIP-seq
MIRT1233489	hsa-miR-4421	CLIP-seq
MIRT1233490	hsa-miR-4433	CLIP-seq
MIRT1233494	hsa-miR-4459	CLIP-seq
MIRT2456478	hsa-miR-4662a-5p	CLIP-seq
MIRT2456479	hsa-miR-4676-5p	CLIP-seq
MIRT1233501	hsa-miR-4683	CLIP-seq
MIRT1233502	hsa-miR-4684-5p	CLIP-seq
MIRT1233506	hsa-miR-4736	CLIP-seq
MIRT2456480	hsa-miR-4755-3p	CLIP-seq
MIRT1233507	hsa-miR-4763-3p	CLIP-seq
MIRT1233508	hsa-miR-4768-3p	CLIP-seq
MIRT1233509	hsa-miR-4786-5p	CLIP-seq
MIRT1233511	hsa-miR-4793-5p	CLIP-seq
MIRT1233512	hsa-miR-4794	CLIP-seq
MIRT2456483	hsa-miR-548c-3p	CLIP-seq
MIRT2456484	hsa-miR-575	CLIP-seq
MIRT1233521	hsa-miR-593	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
AR	Unknown	11171058
IRF1	Unknown	9973374
NFKB1	Unknown	10803841;11714807
RELA	Unknown	10803841
RELB	Activation	15265917
USF1	Activation	14644095
USF1	Unknown	15864740
USF2	Activation	14644095
USF2	Unknown	15864740

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001580	Process	Detection of chemical stimulus involved in sensory perception of bitter taste	IDA	24248522
GO:0001790	Function	Polymeric immunoglobulin binding	IDA	32029689, 36949194
GO:0001792	Function	Polymeric immunoglobulin receptor activity	IDA	22022593
GO:0002415	Process	Immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor	IBA
GO:0002415	Process	Immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor	IDA	9379029, 10229845, 22022593
GO:0004888	Function	Transmembrane signaling receptor activity	IBA
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	HDA	16502470, 22664934, 23580065
GO:0005615	Component	Extracellular space	IDA	24248522
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	9379029, 22022593
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	2920039
GO:0007165	Process	Signal transduction	IBA
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	IDA	22022593
GO:0012505	Component	Endomembrane system	IEA
GO:0016020	Component	Membrane	IEA
GO:0030659	Component	Cytoplasmic vesicle membrane	IEA
GO:0035577	Component	Azurophil granule membrane	TAS
GO:0038093	Process	Fc receptor signaling pathway	IDA	22022593
GO:0043113	Process	Receptor clustering	IDA	22022593
GO:0043235	Component	Receptor complex	IDA	23382219
GO:0070062	Component	Extracellular exosome	HDA	19056867, 19199708, 23533145
GO:0071751	Component	Secretory IgA immunoglobulin complex	IDA	32029686
GO:0098588	Component	Bounding membrane of organelle	IEA

Other IDs

• MIM: 173880
• HGNC: 8968
• e!Ensembl: ENSG00000162896

Protein

• UniProt ID: P01833
• Protein name: Polymeric immunoglobulin receptor (PIgR) (Poly-Ig receptor) (Hepatocellular carcinoma-associated protein TB6) [Cleaved into: Secretory component]
• Protein function: [Polymeric immunoglobulin receptor]: Mediates selective transcytosis of polymeric IgA and IgM across mucosal epithelial cells. Binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the
• PDB: 1XED, 2OCW, 3CHN, 3CM9, 5D4K, 6KXS, 6LX3, 6LXW, 6UE7, 6UE8, 6UE9, 6UEA, 7K0C, 7YSG, 8SKU, 8SKV
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07686	V-set	23 → 128	Immunoglobulin V-set domain	Domain
  PF07686	V-set	136 → 238	Immunoglobulin V-set domain	Domain
  PF07686	V-set	241 → 341	Immunoglobulin V-set domain	Domain
  PF07686	V-set	354 → 457	Immunoglobulin V-set domain	Domain
  PF07686	V-set	465 → 562	Immunoglobulin V-set domain	Domain

• Sequence:

  MLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGA
  RGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLS
  FDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSS
  GYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKP
  EPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLN
  PQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVK
  GVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPG
  NGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKV
  PCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEG
  WYWCGVKQGHFYGETAAVYVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQ
  DPRLFAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTLVPLGLVLAVGAVAVGV
  ARARHRKNVDRVSIRSYRTDISMSDFENSREFGANDNMGASSITQETSLGGKEEFVATTE
  STTETKEPKKAKRSSKEEAEMAYKDFLLQSSTVAAEAQDGPQEA

• Sequence length: 764

Pathways

KEGG:

Intestinal immune network for IgA production

Reactome:

Neutrophil degranulation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CLEAR CELL RENAL CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
IgA glomerulonephritis	Uncertain significance	ClinVar Disgenet	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
KIDNEY CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
STOMACH NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Acute Disease	Associate	19079204, 32362107	★☆☆☆☆ Found in Text Mining only
Adenocarcinoma	Associate	15881224, 18684029, 23243219	★☆☆☆☆ Found in Text Mining only
Adenocarcinoma Mucinous	Associate	24568264	★☆☆☆☆ Found in Text Mining only
Adenocarcinoma Of Esophagus	Associate	18684029	★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Associate	35152150	★☆☆☆☆ Found in Text Mining only
Atrophy	Associate	34928497	★☆☆☆☆ Found in Text Mining only
Bacterial Infections	Stimulate	22025622	★☆☆☆☆ Found in Text Mining only
Barrett Esophagus	Associate	23243219, 24694107	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	31182966, 36207349, 36243728	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Inhibit	40442365	★☆☆☆☆ Found in Text Mining only
Bronchial Diseases	Inhibit	21965228	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Associate	23243219, 32362107	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Associate	22025622, 33390805	★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Associate	24568264	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Associate	33907270	★☆☆☆☆ Found in Text Mining only
Cardio Renal Syndrome	Associate	32427855	★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Associate	32427855	★☆☆☆☆ Found in Text Mining only
Cheilitis glandularis	Associate	36814917	★☆☆☆☆ Found in Text Mining only
Colitis Ulcerative	Inhibit	25956706	★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Associate	8227356, 8664120	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Associate	33378017	★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Associate	28355232, 32427855	★☆☆☆☆ Found in Text Mining only
Crohn Disease	Associate	19079204	★☆☆☆☆ Found in Text Mining only
Crohn Disease	Inhibit	25956706	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Associate	22606001	★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Associate	30964121, 31692912	★☆☆☆☆ Found in Text Mining only
Epstein Barr Virus Infections	Associate	12546713	★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Associate	18684029, 24694107, 35429246	★☆☆☆☆ Found in Text Mining only
Fibrosis	Associate	33390805	★☆☆☆☆ Found in Text Mining only
Fibrosis	Stimulate	33937393	★☆☆☆☆ Found in Text Mining only
Glomerulonephritis IGA	Associate	11579946	★☆☆☆☆ Found in Text Mining only
Heart Failure	Associate	32427855	★☆☆☆☆ Found in Text Mining only
Hepatitis B	Stimulate	33937393	★☆☆☆☆ Found in Text Mining only
Idiopathic Pulmonary Fibrosis	Associate	31640794, 32362107	★☆☆☆☆ Found in Text Mining only
Inflammation	Associate	19079204, 22025622, 28355232	★☆☆☆☆ Found in Text Mining only
Inflammation	Stimulate	31404540	★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Associate	32697969, 33930428	★☆☆☆☆ Found in Text Mining only
Intestinal Diseases	Associate	18684029	★☆☆☆☆ Found in Text Mining only
Intestinal Diseases	Stimulate	24694107	★☆☆☆☆ Found in Text Mining only
Keratoconus	Inhibit	24194634	★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Associate	31404540, 32427855	★☆☆☆☆ Found in Text Mining only
Leukemia Lymphocytic Chronic B Cell	Associate	29196338, 29367434	★☆☆☆☆ Found in Text Mining only
Liver Cirrhosis	Stimulate	33937393	★☆☆☆☆ Found in Text Mining only
Lung Diseases	Inhibit	21965228	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Inhibit	21965228	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Inhibit	25397670	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Associate	33819484	★☆☆☆☆ Found in Text Mining only
Mallory Weiss Syndrome	Associate	18684029, 24694107	★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Inhibit	26910773	★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Associate	27350400	★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Neoplasms	Associate	12546713	★☆☆☆☆ Found in Text Mining only
Neoplasm Metastasis	Associate	22025622, 33378017	★☆☆☆☆ Found in Text Mining only
Neoplasm Metastasis	Inhibit	26910773	★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	15881224, 18684029, 22025622, 23359139, 24568264, 24699841, 25652121, 33390805, 35429246, 36207349	★☆☆☆☆ Found in Text Mining only
Neoplasms	Inhibit	24694107, 25397670, 33110154	★☆☆☆☆ Found in Text Mining only
Neoplasms Cystic Mucinous and Serous	Inhibit	24568264	★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Associate	24699841	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Associate	21653254, 23359139, 25397670	★☆☆☆☆ Found in Text Mining only
Periodontitis	Associate	22606001	★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Associate	21512171, 30970352	★☆☆☆☆ Found in Text Mining only
Retinal Dysplasia	Associate	23243219	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Associate	18684029, 24694107	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Tertiary Lymphoid Structures	Associate	33390805	★☆☆☆☆ Found in Text Mining only
Virus Diseases	Stimulate	22025622	★☆☆☆☆ Found in Text Mining only