SLC25A3 (solute carrier family 25 member 3)

Gene

• Entrez ID: 5250
• Gene name: Solute carrier family 25 member 3
• Gene symbol: SLC25A3
• Synonyms (NCBI Gene): OK/SW-cl.48, PHC, PTP, PiC
• Chromosome: 12
• Chromosome location: 12q23.1
• Summary: The protein encoded by this gene catalyzes the transport of phosphate into the mitochondrial matrix, either by proton cotransport or in exchange for hydroxyl ions. The protein contains three related segments arranged in tandem which are related to those f

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs104894375	G>A	Pathogenic	Coding sequence variant, intron variant, missense variant
rs745305932	A>G	Pathogenic-likely-pathogenic	Intron variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT050860	hsa-miR-17-5p	CLASH	23622248
MIRT048927	hsa-miR-92a-3p	CLASH	23622248
MIRT048032	hsa-miR-148a-3p	CLASH	23622248
MIRT043170	hsa-miR-324-5p	CLASH	23622248
MIRT039345	hsa-miR-425-5p	CLASH	23622248
MIRT037487	hsa-miR-744-5p	CLASH	23622248
MIRT037487	hsa-miR-744-5p	CLASH	23622248
MIRT037303	hsa-miR-877-5p	CLASH	23622248
MIRT052685	hsa-miR-1260b	CLASH	23622248
MIRT052685	hsa-miR-1260b	CLASH	23622248
MIRT1356365	hsa-miR-3074-3p	CLIP-seq
MIRT1356366	hsa-miR-873	CLIP-seq
MIRT2105541	hsa-miR-141	CLIP-seq
MIRT2105542	hsa-miR-1910	CLIP-seq
MIRT2105543	hsa-miR-200a	CLIP-seq
MIRT2105544	hsa-miR-224	CLIP-seq
MIRT2105545	hsa-miR-3065-5p	CLIP-seq
MIRT2105546	hsa-miR-3163	CLIP-seq
MIRT2105547	hsa-miR-3671	CLIP-seq
MIRT2105548	hsa-miR-3685	CLIP-seq
MIRT2105549	hsa-miR-384	CLIP-seq
MIRT2105550	hsa-miR-410	CLIP-seq
MIRT2105551	hsa-miR-421	CLIP-seq
MIRT2105552	hsa-miR-4325	CLIP-seq
MIRT2105553	hsa-miR-450b-5p	CLIP-seq
MIRT2105554	hsa-miR-455-3p	CLIP-seq
MIRT2105555	hsa-miR-4659a-3p	CLIP-seq
MIRT2105556	hsa-miR-4659b-3p	CLIP-seq
MIRT2105557	hsa-miR-4742-5p	CLIP-seq
MIRT2105558	hsa-miR-507	CLIP-seq
MIRT2105559	hsa-miR-513a-5p	CLIP-seq
MIRT2105560	hsa-miR-548c-3p	CLIP-seq
MIRT2105561	hsa-miR-557	CLIP-seq
MIRT2105541	hsa-miR-141	CLIP-seq
MIRT2105542	hsa-miR-1910	CLIP-seq
MIRT2105543	hsa-miR-200a	CLIP-seq
MIRT2105545	hsa-miR-3065-5p	CLIP-seq
MIRT2330046	hsa-miR-3940-5p	CLIP-seq
MIRT2105551	hsa-miR-421	CLIP-seq
MIRT2330047	hsa-miR-4259	CLIP-seq
MIRT2105552	hsa-miR-4325	CLIP-seq
MIRT2330048	hsa-miR-4507	CLIP-seq
MIRT2105553	hsa-miR-450b-5p	CLIP-seq
MIRT2105554	hsa-miR-455-3p	CLIP-seq
MIRT2105555	hsa-miR-4659a-3p	CLIP-seq
MIRT2105556	hsa-miR-4659b-3p	CLIP-seq
MIRT2105558	hsa-miR-507	CLIP-seq
MIRT2105561	hsa-miR-557	CLIP-seq
MIRT2330049	hsa-miR-571	CLIP-seq
MIRT2330050	hsa-miR-629	CLIP-seq
MIRT2105541	hsa-miR-141	CLIP-seq
MIRT2105543	hsa-miR-200a	CLIP-seq
MIRT2105551	hsa-miR-421	CLIP-seq
MIRT2105552	hsa-miR-4325	CLIP-seq
MIRT2105555	hsa-miR-4659a-3p	CLIP-seq
MIRT2105556	hsa-miR-4659b-3p	CLIP-seq
MIRT2105558	hsa-miR-507	CLIP-seq
MIRT2105561	hsa-miR-557	CLIP-seq
MIRT2433228	hsa-miR-4503	CLIP-seq
MIRT2433229	hsa-miR-451b	CLIP-seq
MIRT2433230	hsa-miR-4738-3p	CLIP-seq
MIRT2624219	hsa-miR-101	CLIP-seq
MIRT2624220	hsa-miR-139-5p	CLIP-seq
MIRT2105541	hsa-miR-141	CLIP-seq
MIRT2624221	hsa-miR-144	CLIP-seq
MIRT2105542	hsa-miR-1910	CLIP-seq
MIRT2105543	hsa-miR-200a	CLIP-seq
MIRT2105545	hsa-miR-3065-5p	CLIP-seq
MIRT1356365	hsa-miR-3074-3p	CLIP-seq
MIRT2105546	hsa-miR-3163	CLIP-seq
MIRT2105547	hsa-miR-3671	CLIP-seq
MIRT2105548	hsa-miR-3685	CLIP-seq
MIRT2105549	hsa-miR-384	CLIP-seq
MIRT2105550	hsa-miR-410	CLIP-seq
MIRT2105551	hsa-miR-421	CLIP-seq
MIRT2105552	hsa-miR-4325	CLIP-seq
MIRT2433228	hsa-miR-4503	CLIP-seq
MIRT2105553	hsa-miR-450b-5p	CLIP-seq
MIRT2433229	hsa-miR-451b	CLIP-seq
MIRT2105554	hsa-miR-455-3p	CLIP-seq
MIRT2105555	hsa-miR-4659a-3p	CLIP-seq
MIRT2105556	hsa-miR-4659b-3p	CLIP-seq
MIRT2433230	hsa-miR-4738-3p	CLIP-seq
MIRT2105558	hsa-miR-507	CLIP-seq
MIRT2624222	hsa-miR-548n	CLIP-seq
MIRT2624223	hsa-miR-548t	CLIP-seq
MIRT2105561	hsa-miR-557	CLIP-seq
MIRT1356366	hsa-miR-873	CLIP-seq
MIRT2624224	hsa-miR-944	CLIP-seq
MIRT2624219	hsa-miR-101	CLIP-seq
MIRT2624220	hsa-miR-139-5p	CLIP-seq
MIRT2105541	hsa-miR-141	CLIP-seq
MIRT2624221	hsa-miR-144	CLIP-seq
MIRT2105542	hsa-miR-1910	CLIP-seq
MIRT2105543	hsa-miR-200a	CLIP-seq
MIRT2105545	hsa-miR-3065-5p	CLIP-seq
MIRT1356365	hsa-miR-3074-3p	CLIP-seq
MIRT2105546	hsa-miR-3163	CLIP-seq
MIRT2105547	hsa-miR-3671	CLIP-seq
MIRT2105548	hsa-miR-3685	CLIP-seq
MIRT2105549	hsa-miR-384	CLIP-seq
MIRT2105550	hsa-miR-410	CLIP-seq
MIRT2105551	hsa-miR-421	CLIP-seq
MIRT2105552	hsa-miR-4325	CLIP-seq
MIRT2433228	hsa-miR-4503	CLIP-seq
MIRT2105553	hsa-miR-450b-5p	CLIP-seq
MIRT2433229	hsa-miR-451b	CLIP-seq
MIRT2105554	hsa-miR-455-3p	CLIP-seq
MIRT2105555	hsa-miR-4659a-3p	CLIP-seq
MIRT2105556	hsa-miR-4659b-3p	CLIP-seq
MIRT2433230	hsa-miR-4738-3p	CLIP-seq
MIRT2105558	hsa-miR-507	CLIP-seq
MIRT2624222	hsa-miR-548n	CLIP-seq
MIRT2624223	hsa-miR-548t	CLIP-seq
MIRT2105561	hsa-miR-557	CLIP-seq
MIRT1356366	hsa-miR-873	CLIP-seq
MIRT2624224	hsa-miR-944	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005315	Function	Inorganic phosphate transmembrane transporter activity	IBA	21873635
GO:0005739	Component	Mitochondrion	IDA
GO:0005743	Component	Mitochondrial inner membrane	TAS	8144629
GO:0005887	Component	Integral component of plasma membrane	TAS	8144629
GO:0015317	Function	Phosphate:proton symporter activity	TAS	8144629
GO:0016020	Component	Membrane	HDA	19946888
GO:0031305	Component	Integral component of mitochondrial inner membrane	IBA	21873635
GO:0035435	Process	Phosphate ion transmembrane transport	IBA	21873635
GO:0044877	Function	Protein-containing complex binding	IDA	23209302
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:1902600	Process	Proton transmembrane transport	IEA

Other IDs

• MIM: 600370
• HGNC: 10989
• e!Ensembl: ENSG00000075415

Protein

• UniProt ID: Q00325
• Protein name: Solute carrier family 25 member 3 (Phosphate carrier protein, mitochondrial) (Phosphate transport protein) (PTP)
• Protein function: Inorganic ion transporter that transports phosphate or copper ions across the mitochondrial inner membrane into the matrix compartment (By similarity) (PubMed:17273968, PubMed:29237729). Mediates proton-coupled symport of phosphate ions necessar
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00153	Mito_carr	63 → 152	Mitochondrial carrier protein	Family
  PF00153	Mito_carr	161 → 249	Mitochondrial carrier protein	Family
  PF00153	Mito_carr	259 → 343	Mitochondrial carrier protein	Family

• Sequence:

  MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEQYSCDYG
  SGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA
  KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL
  APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER
  TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS
  LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL
  TQ

• Sequence length: 362

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Cardiomyopathy-hypotonia-lactic acidosis syndrome	Cardiomyopathy-hypotonia-lactic acidosis syndrome	rs104894375, rs745305932
Hypertrophic cardiomyopathy	Hypertrophic Cardiomyopathy	rs63750743, rs104894655, rs121908987, rs587776643, rs28938173, rs121908989, rs121908991, rs267606977, rs267606978, rs193922384, rs121909374, rs886041030, rs886041031, rs121909375, rs121909377, rs2856655, rs587776700, rs387906397, rs104894204, rs121434470, rs104894828, rs121964855, rs121964856, rs121964858, rs74315380, rs104894724, rs104894725, rs104894727, rs104894728, rs104894729, rs104894730, rs267607127, rs2147283135, rs267607128, rs267607125, rs104894502, rs104894503, rs104894504, rs28933405, rs111033560, rs121434594, rs80338797, rs104893748, rs104894368, rs104894369, rs104894370, rs121913624, rs3218713, rs121913625, rs121913626, rs121913627, rs121913628, rs121913629, rs121913630, rs121913631, rs121913632, rs121913633, rs121913634, rs3218714, rs121913636, rs121913637, rs121913638, rs121913639, rs121913641, rs121913642, rs121913643, rs121913647, rs121913650, rs121913651, rs36211715, rs121913654, rs267606911, rs267606908, rs730880850, rs121912675, rs267606629, rs193922680, rs1600482909, rs387906898, rs199476398, rs387907079, rs199474815, rs199474703, rs199476305, rs199476306, rs199476315, rs199476316, rs199476317, rs199476321, rs199476311, rs193922649, rs36211723, rs187830361, rs193922383, rs193922386, rs193922390, rs193922697, rs387907267, rs397507520, rs727505017, rs397515888, rs397515889, rs397515891, rs397515893, rs397515894, rs397515895, rs397515896, rs397515897, rs397515903, rs397515905, rs375882485, rs397515907, rs397515910, rs397515912, rs397515916, rs397515920, rs397515925, rs397515926, rs397515931, rs397515933, rs397515934, rs397515935, rs397515937, rs397515942, rs397515943, rs397515944, rs397515947, rs397515948, rs397515952, rs397515954, rs112738974, rs111729952, rs397515960, rs397515963, rs397515965, rs397515966, rs397515970, rs397515972, rs397515973, rs397515974, rs397515975, rs397515977, rs376395543, rs397515979, rs397515982, rs397515987, rs397515990, rs397515991, rs397515992, rs397515995, rs397515997, rs397516001, rs397516005, rs113358486, rs397516006, rs397516007, rs397516008, rs397516010, rs397516013, rs397516014, rs373746463, rs397516019, rs397516020, rs397516022, rs397516023, rs397516029, rs397516031, rs397516032, rs397516035, rs397516037, rs397516038, rs397516040, rs397516042, rs397516044, rs397516047, rs397516049, rs397516052, rs397516056, rs397516057, rs397516058, rs397516059, rs397516061, rs397516067, rs397516068, rs397516070, rs397516072, rs397516073, rs397516074, rs397516076, rs397516077, rs397516080, rs201078659, rs397516082, rs397516083, rs1555122751, rs397516088, rs397516089, rs397516095, rs397516098, rs397516101, rs397516103, rs397516110, rs397516127, rs371898076, rs397516132, rs397516134, rs397516142, rs3218716, rs397516153, rs397516154, rs397516155, rs397516156, rs397516157, rs397516160, rs397516161, rs397516165, rs397516166, rs397516170, rs397516171, rs397516172, rs397516178, rs397516179, rs397516187, rs397516201, rs397516202, rs145213771, rs397516207, rs397516209, rs397516212, rs397516238, rs397516248, rs397516254, rs397516258, rs397516260, rs45516091, rs397516264, rs397516266, rs397516269, rs397516340, rs397516347, rs121917760, rs397516349, rs397516353, rs397516354, rs397516355, rs397516357, rs397516373, rs397516406, rs397516455, rs397516456, rs397516457, rs397516463, rs397516464, rs45525839, rs397516470, rs397516471, rs45578238, rs111377893, rs397516736, rs397516738, rs397516739, rs397516751, rs397516752, rs397516784, rs397517283, rs397514752, rs143697995, rs267607490, rs199472948, rs138193236, rs398123279, rs869320740, rs606231340, rs606231324, rs587779392, rs587779393, rs587782951, rs587782957, rs587782958, rs587782962, rs587782965, rs138049878, rs376897125, rs368765949, rs727504247, rs376923877, rs727504277, rs727504255, rs727504246, rs727504331, rs727503513, rs727504392, rs397516039, rs727504271, rs727504321, rs727504289, rs727504305, rs727503172, rs573821685, rs727503176, rs727503178, rs727504423, rs727503180, rs727504333, rs727503182, rs727504265, rs727503184, rs727503186, rs727503187, rs727504252, rs727504864, rs727504334, rs727503192, rs397515932, rs727504366, rs727504248, rs727504287, rs200411226, rs727503204, rs727504329, rs727504269, rs573916965, rs367947846, rs727503210, rs730880335, rs727503166, rs727504390, rs730880361, rs727504276, rs111683277, rs727503174, rs727503175, rs727504349, rs727504314, rs727504371, rs730880341, rs727504293, rs727503195, rs111437311, rs727503202, rs727503203, rs727504279, rs727505152, rs727503209, rs727503211, rs727503212, rs727503217, rs727503219, rs730880366, rs727503220, rs727504356, rs727504311, rs727503261, rs727503264, rs727504238, rs148808089, rs727503271, rs727504409, rs727503276, rs727504283, rs727503296, rs45544633, rs727503246, rs727503252, rs727503253, rs202141173, rs2754158, rs727504310, rs727503260, rs727504272, rs727504240, rs727503263, rs727504239, rs727504925, rs727504237, rs727504236, rs727505202, rs727504267, rs727503278, rs727504243, rs727504285, rs727503499, rs727503504, rs727504242, rs727504264, rs727504275, rs727503500, rs727503503, rs727503120, rs730880336, rs730880337, rs730880362, rs730880210, rs730880143, rs730880159, rs730881116, rs730881122, rs730880162, rs730880605, rs730880604, rs730880600, rs730880702, rs730880598, rs730880597, rs730880699, rs730880592, rs730880675, rs730880720, rs730880719, rs730880672, rs730880668, rs730880718, rs730880666, rs730880586, rs730880584, rs11570112, rs730880578, rs730880576, rs730880660, rs730880657, rs730880655, rs730880654, rs730880653, rs730880652, rs730880714, rs730880651, rs730880558, rs730880649, rs730880647, rs730880713, rs730880646, rs730880546, rs727503197, rs730880695, rs730880644, rs730880640, rs730880712, rs730880544, rs730880542, rs730880541, rs730880538, rs730880533, rs730880531, rs730880641, rs730880639, rs397515890, rs730880724, rs730880635, rs730880723, rs730880686, rs730880631, rs730880678, rs730880629, rs730880684, rs368121566, rs730880621, rs730880681, rs375607980, rs730880618, rs730880680, rs730880679, rs730880677, rs730880704, rs730880703, rs730880721, rs730880698, rs730880664, rs730880663, rs730880662, rs730880659, rs730880916, rs727504558, rs730880759, rs730880756, rs730880750, rs730880749, rs730880748, rs730880736, rs727504241, rs727504299, rs730880732, rs730880883, rs730880930, rs730880929, rs730880875, rs370310929, rs730880926, rs730880864, rs730880856, rs397516268, rs730880922, rs730880845, rs730880388, rs730881091, rs786204352, rs786204339, rs786204338, rs786204336, rs786204329, rs2069544, rs281865416, rs773317399, rs121913648, rs730880809, rs863224483, rs863224899, rs863224900, rs863225120, rs863225121, rs863225107, rs863225114, rs863225113, rs863225104, rs863225105, rs863225112, rs863225106, rs863225109, rs863225111, rs863225100, rs863225103, rs863225102, rs863225097, rs863225101, rs730880876, rs863225272, rs863225271, rs190228518, rs863225269, rs761507504, rs864622224, rs1057515421, rs869025470, rs869025469, rs869025461, rs869025468, rs869025460, rs869025467, rs869025466, rs869025465, rs869025464, rs869025463, rs869025459, rs869025462, rs727503512, rs876657706, rs876657705, rs876657703, rs876657702, rs727503213, rs876657884, rs878854428, rs878853831, rs878853842, rs1562999443, rs1563003848, rs1562991002, rs879255639, rs886037900, rs886037902, rs886037901, rs886038822, rs886039030, rs886039185, rs754664923, rs141019458, rs1057517766, rs1057517767, rs779650200, rs1057518030, rs1057517711, rs1057519503, rs1057520814, rs1060499673, rs1060501480, rs1060501484, rs1060501481, rs1060501478, rs1064792936, rs1060501475, rs1060501479, rs1064792935, rs1060501436, rs1060501448, rs1060501443, rs1060501452, rs1060505018, rs1060499604, rs781135153, rs1064796231, rs1064793202, rs977277400, rs1064793429, rs771929829, rs745811346, rs1114167419, rs1114167361, rs1555409659, rs1555123389, rs1131691514, rs1131692185, rs1131692058, rs1553279294, rs1555120920, rs1555121924, rs1555338319, rs1555120300, rs1555121488, rs373792537, rs1444727212, rs1555338462, rs1555120937, rs1555123629, rs794727046, rs1555123633, rs1555121172, rs1555123438, rs1555336467, rs1555338658, rs1213930919, rs1432810664, rs1555122188, rs764743402, rs974671846, rs1420159591, rs745688425, rs1555338080, rs200889953, rs1555120258, rs1298025872, rs767039057, rs1555120529, rs1555121247, rs774521272, rs1555122156, rs1555123473, rs1555123496, rs1555123597, rs1555337701, rs2856897, rs869312381, rs1555122928, rs1555123743, rs1554401581, rs1555120651, rs868819340, rs1555122053, rs730880742, rs758891557, rs1555337794, rs1555338378, rs1555338758, rs1245885836, rs1566530698, rs1566513862, rs1565629792, rs730880751, rs727504294, rs1563001548, rs1565622952, rs1565625473, rs1565626409, rs1565627536, rs1565628062, rs1565628486, rs1565631430, rs1391622163, rs1131691685, rs749007293, rs1566535491, rs1565624090, rs1565625777, rs1565631428, rs1568858210, rs1566537070, rs1565627566, rs1567864804, rs1563161306, rs1565622703, rs190765116, rs1595843598, rs1565625795, rs1565628078, rs774316050, rs1565631381, rs1565631424, rs1566531421, rs730880872, rs730880870, rs1566536418, rs1566536436, rs1565623216, rs1265248322, rs113276889, rs1562998062, rs1419032418, rs1565627615, rs1565624196, rs1595843640, rs1595846398, rs764950910, rs1600448065, rs1600462474, rs1417887060, rs1600477808, rs1600480573, rs1050997719, rs1420394583, rs1595840648, rs1595841063, rs1595843549, rs1595843758, rs1595845565, rs1595845888, rs1595846344, rs1595846475, rs1595849931, rs1595070747, rs1246272841, rs730880741, rs1173617248, rs1595085409, rs730880879, rs1299079662, rs1595848628, rs1595849603, rs1450218521, rs1571627587, rs1603037717, rs1603038411, rs1595850762, rs777702465, rs1595841736, rs1595842238, rs1595845204, rs1025692267, rs1595070689, rs1198682781, rs2095879705, rs201911056, rs727504425, rs141414377, rs1596303148, rs1595841206, rs1595844714, rs1595842632, rs1595843828, rs113709679, rs1595841552, rs1595849742, rs754529157, rs1709195189, rs1342121466, rs2095880935, rs2095883508, rs2095884984, rs2095889902, rs2095891411, rs2095898532, rs780625785, rs1892592854, rs1892948780, rs2095879167, rs1956121988, rs2095893477, rs2095894178, rs1801002279, rs1892956157
Myopathy	Myopathy	rs137854521, rs386834236, rs121908557, rs121909092, rs111033570, rs104894299, rs104894294, rs121909273, rs121909274, rs121909275, rs199474699, rs199476140, rs118192165, rs118192169, rs118192166, rs193922856, rs281865489, rs397514675, rs397514676, rs397514677, rs367543058, rs118192117, rs193922837, rs118192129, rs118192143, rs118192153, rs118192133, rs118192156, rs118192149, rs118192148, rs118192183, rs118192147, rs118192123, rs118192127, rs118192142, rs118192144, rs118192178, rs118192151, rs118192150, rs118192184, rs118192154, rs118192134, rs118192155, rs193922893, rs118192132, rs118192146, rs193922867, rs193922884, rs587777528, rs527236030, rs587777672, rs587777673, rs587777674, rs587777675, rs587783343, rs2754158, rs786204796, rs748277951, rs797046047, rs797046064, rs797046060, rs797045479, rs797045931, rs797045932, rs797045934, rs797045935, rs797045477, rs797045478, rs1057518851, rs1057518855, rs1057518773, rs1057518866, rs1555322610, rs1555806119, rs761483896, rs144071404, rs1198364572, rs1568614042, rs978984063, rs1568604308, rs1332371891, rs1601842249, rs777176261, rs1249621033, rs1278804520, rs1568613962, rs1568510406, rs1597512576, rs193922887, rs371455345, rs1603452200, rs1599634685, rs1575065895, rs1575201712, rs139715157, rs1974129338

Unknown
Disease term	Disease name	Evidence	References	Source
Congestive heart failure	Low-output congestive heart failure			ClinVar
Mitochondrial Diseases	mitochondrial disease			GenCC

Associations from Text Mining
Disease Name	Relationship Type	References
Acidosis Lactic	Associate	17273968, 39671292
Blast Crisis	Associate	19654405
Cardiomegaly	Associate	39671292
Cardiomyopathy Hypertrophic	Associate	17273968, 39671292
Colorectal Neoplasms	Inhibit	35924107
Death	Associate	17273968, 39671292
Hypertrophy	Associate	39671292
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	19654405
Mitochondrial Diseases	Associate	17273968, 33615715, 39671292
Mitochondrial Phosphate Carrier Deficiency	Associate	17273968
Muscle Hypotonia	Associate	17273968
Renal Insufficiency	Associate	33615715
Ventricular Dysfunction Left	Associate	39671292