Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5245
Gene name	Prohibitin 1
Gene symbol	PHB1
Synonyms (NCBI Gene)	BAP32HEL-215HEL-S-54ePHB
Chromosome	17
Chromosome location	17q21.33

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SNP ID	Visualize variation	Clinical significance	Consequence
rs112294663	G>A,C,T	Risk-factor	3 prime UTR variant

428

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001210	hsa-miR-27a-3p	qRT-PCRGFP reporter assayWestern blot	18789835
MIRT001210	hsa-miR-27a-3p	qRT-PCRGFP reporter assayWestern blot	18789835
MIRT001210	hsa-miR-27a-3p	ChIP-seqLuciferase reporter assayNorthern blotqRT-PCRWestern blot	22505583
MIRT001210	hsa-miR-27a-3p	ChIP-seqLuciferase reporter assayNorthern blotqRT-PCRWestern blot	22505583
MIRT001210	hsa-miR-27a-3p	ChIP-seqLuciferase reporter assayNorthern blotqRT-PCRWestern blot	22505583
MIRT001210	hsa-miR-27a-3p	ChIP-seqLuciferase reporter assayNorthern blotqRT-PCRWestern blot	22505583
MIRT001210	hsa-miR-27a-3p	ChIP-seqLuciferase reporter assayNorthern blotqRT-PCRWestern blot	22505583
MIRT001210	hsa-miR-27a-3p	ChIP-seqLuciferase reporter assayNorthern blotqRT-PCRWestern blot	22505583
MIRT041678	hsa-miR-484	CLASH	23622248
MIRT438656	hsa-miR-26a-5p	Luciferase reporter assayqRT-PCRWestern blot	23870455
MIRT438656	hsa-miR-26a-5p	Luciferase reporter assayqRT-PCRWestern blot	23870455
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assay	24133204
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assay	24133204
MIRT438627	hsa-miR-27b-3p	Luciferase reporter assay	24133204
MIRT438627	hsa-miR-27b-3p	Luciferase reporter assay	24133204
MIRT438656	hsa-miR-26a-5p	Luciferase reporter assayqRT-PCRWestern blot	23870455
MIRT438656	hsa-miR-26a-5p	Luciferase reporter assayqRT-PCRWestern blot	23870455
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assay	24133204
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assay	24133204
MIRT438627	hsa-miR-27b-3p	Luciferase reporter assay	24133204
MIRT438627	hsa-miR-27b-3p	Luciferase reporter assay	24133204
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assayMicroarrayqRT-PCR	25915942
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assay	25777779
MIRT1229383	hsa-miR-1252	CLIP-seq
MIRT1229384	hsa-miR-1264	CLIP-seq
MIRT1229385	hsa-miR-128	CLIP-seq
MIRT1229386	hsa-miR-1284	CLIP-seq
MIRT1229387	hsa-miR-205	CLIP-seq
MIRT1229388	hsa-miR-2277-3p	CLIP-seq
MIRT1229389	hsa-miR-27a	CLIP-seq
MIRT1229390	hsa-miR-27b	CLIP-seq
MIRT1229391	hsa-miR-298	CLIP-seq
MIRT1229392	hsa-miR-300	CLIP-seq
MIRT1229393	hsa-miR-3125	CLIP-seq
MIRT1229394	hsa-miR-3126-5p	CLIP-seq
MIRT1229395	hsa-miR-3132	CLIP-seq
MIRT1229396	hsa-miR-3136-3p	CLIP-seq
MIRT1229397	hsa-miR-3152-3p	CLIP-seq
MIRT1229398	hsa-miR-3183	CLIP-seq
MIRT1229399	hsa-miR-3200-5p	CLIP-seq
MIRT1229400	hsa-miR-342-5p	CLIP-seq
MIRT1229401	hsa-miR-3616-5p	CLIP-seq
MIRT1229402	hsa-miR-3647-5p	CLIP-seq
MIRT1229403	hsa-miR-3653	CLIP-seq
MIRT1229404	hsa-miR-3658	CLIP-seq
MIRT1229405	hsa-miR-3689d	CLIP-seq
MIRT1229406	hsa-miR-381	CLIP-seq
MIRT1229407	hsa-miR-3916	CLIP-seq
MIRT1229408	hsa-miR-421	CLIP-seq
MIRT1229409	hsa-miR-4251	CLIP-seq
MIRT1229410	hsa-miR-4300	CLIP-seq
MIRT1229411	hsa-miR-4314	CLIP-seq
MIRT1229412	hsa-miR-4329	CLIP-seq
MIRT1229413	hsa-miR-4447	CLIP-seq
MIRT1229414	hsa-miR-4451	CLIP-seq
MIRT1229415	hsa-miR-4468	CLIP-seq
MIRT1229416	hsa-miR-4472	CLIP-seq
MIRT1229417	hsa-miR-4476	CLIP-seq
MIRT1229418	hsa-miR-4503	CLIP-seq
MIRT1229419	hsa-miR-4508	CLIP-seq
MIRT1229420	hsa-miR-4643	CLIP-seq
MIRT1229421	hsa-miR-4645-5p	CLIP-seq
MIRT1229422	hsa-miR-4650-5p	CLIP-seq
MIRT1229423	hsa-miR-4651	CLIP-seq
MIRT1229424	hsa-miR-466	CLIP-seq
MIRT1229425	hsa-miR-4664-5p	CLIP-seq
MIRT1229426	hsa-miR-4666-3p	CLIP-seq
MIRT1229427	hsa-miR-4667-5p	CLIP-seq
MIRT1229428	hsa-miR-4673	CLIP-seq
MIRT1229429	hsa-miR-4675	CLIP-seq
MIRT1229430	hsa-miR-4690-3p	CLIP-seq
MIRT1229431	hsa-miR-4700-3p	CLIP-seq
MIRT1229432	hsa-miR-4700-5p	CLIP-seq
MIRT1229433	hsa-miR-4709-5p	CLIP-seq
MIRT1229434	hsa-miR-4723-3p	CLIP-seq
MIRT1229435	hsa-miR-4724-3p	CLIP-seq
MIRT1229436	hsa-miR-4729	CLIP-seq
MIRT1229437	hsa-miR-4741	CLIP-seq
MIRT1229438	hsa-miR-4746-5p	CLIP-seq
MIRT1229439	hsa-miR-4761-5p	CLIP-seq
MIRT1229440	hsa-miR-4789-3p	CLIP-seq
MIRT1229441	hsa-miR-4789-5p	CLIP-seq
MIRT1229442	hsa-miR-4795-5p	CLIP-seq
MIRT1229443	hsa-miR-513a-3p	CLIP-seq
MIRT1229444	hsa-miR-513a-5p	CLIP-seq
MIRT1229445	hsa-miR-573	CLIP-seq
MIRT1229446	hsa-miR-608	CLIP-seq
MIRT1229447	hsa-miR-616	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT1229449	hsa-miR-658	CLIP-seq
MIRT1229450	hsa-miR-663b	CLIP-seq
MIRT1229451	hsa-miR-920	CLIP-seq
MIRT2067179	hsa-miR-1207-5p	CLIP-seq
MIRT1229383	hsa-miR-1252	CLIP-seq
MIRT1229385	hsa-miR-128	CLIP-seq
MIRT2067180	hsa-miR-132	CLIP-seq
MIRT1229387	hsa-miR-205	CLIP-seq
MIRT2067181	hsa-miR-212	CLIP-seq
MIRT1229389	hsa-miR-27a	CLIP-seq
MIRT1229390	hsa-miR-27b	CLIP-seq
MIRT1229391	hsa-miR-298	CLIP-seq
MIRT1229397	hsa-miR-3152-3p	CLIP-seq
MIRT1229400	hsa-miR-342-5p	CLIP-seq
MIRT1229403	hsa-miR-3653	CLIP-seq
MIRT1229404	hsa-miR-3658	CLIP-seq
MIRT1229405	hsa-miR-3689d	CLIP-seq
MIRT2067182	hsa-miR-4292	CLIP-seq
MIRT1229410	hsa-miR-4300	CLIP-seq
MIRT1229411	hsa-miR-4314	CLIP-seq
MIRT1229415	hsa-miR-4468	CLIP-seq
MIRT1229417	hsa-miR-4476	CLIP-seq
MIRT1229418	hsa-miR-4503	CLIP-seq
MIRT2067183	hsa-miR-4514	CLIP-seq
MIRT1229423	hsa-miR-4651	CLIP-seq
MIRT1229425	hsa-miR-4664-5p	CLIP-seq
MIRT1229427	hsa-miR-4667-5p	CLIP-seq
MIRT1229430	hsa-miR-4690-3p	CLIP-seq
MIRT2067184	hsa-miR-4692	CLIP-seq
MIRT1229432	hsa-miR-4700-5p	CLIP-seq
MIRT1229433	hsa-miR-4709-5p	CLIP-seq
MIRT1229435	hsa-miR-4724-3p	CLIP-seq
MIRT2067185	hsa-miR-4725-5p	CLIP-seq
MIRT2067186	hsa-miR-4763-3p	CLIP-seq
MIRT2067187	hsa-miR-504	CLIP-seq
MIRT1229443	hsa-miR-513a-3p	CLIP-seq
MIRT1229444	hsa-miR-513a-5p	CLIP-seq
MIRT1229446	hsa-miR-608	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT1229449	hsa-miR-658	CLIP-seq
MIRT1229451	hsa-miR-920	CLIP-seq
MIRT2067188	hsa-miR-940	CLIP-seq
MIRT2294704	hsa-miR-103a	CLIP-seq
MIRT2294705	hsa-miR-105	CLIP-seq
MIRT2294706	hsa-miR-107	CLIP-seq
MIRT2067179	hsa-miR-1207-5p	CLIP-seq
MIRT2294707	hsa-miR-1224-3p	CLIP-seq
MIRT2294708	hsa-miR-1228	CLIP-seq
MIRT2294709	hsa-miR-1236	CLIP-seq
MIRT1229383	hsa-miR-1252	CLIP-seq
MIRT2294710	hsa-miR-1253	CLIP-seq
MIRT2294711	hsa-miR-1261	CLIP-seq
MIRT1229384	hsa-miR-1264	CLIP-seq
MIRT2294712	hsa-miR-1271	CLIP-seq
MIRT2294713	hsa-miR-1276	CLIP-seq
MIRT1229385	hsa-miR-128	CLIP-seq
MIRT1229386	hsa-miR-1284	CLIP-seq
MIRT2294714	hsa-miR-1297	CLIP-seq
MIRT2067180	hsa-miR-132	CLIP-seq
MIRT2294715	hsa-miR-1321	CLIP-seq
MIRT2294716	hsa-miR-138	CLIP-seq
MIRT2294717	hsa-miR-148a	CLIP-seq
MIRT2294718	hsa-miR-148b	CLIP-seq
MIRT2294719	hsa-miR-152	CLIP-seq
MIRT2294720	hsa-miR-153	CLIP-seq
MIRT2294721	hsa-miR-15a	CLIP-seq
MIRT2294722	hsa-miR-15b	CLIP-seq
MIRT2294723	hsa-miR-16	CLIP-seq
MIRT2294724	hsa-miR-182	CLIP-seq
MIRT2294725	hsa-miR-1825	CLIP-seq
MIRT2294726	hsa-miR-1913	CLIP-seq
MIRT2294727	hsa-miR-195	CLIP-seq
MIRT2294728	hsa-miR-1972	CLIP-seq
MIRT1229387	hsa-miR-205	CLIP-seq
MIRT2067181	hsa-miR-212	CLIP-seq
MIRT2294729	hsa-miR-214	CLIP-seq
MIRT1229388	hsa-miR-2277-3p	CLIP-seq
MIRT2294730	hsa-miR-26a	CLIP-seq
MIRT2294731	hsa-miR-26b	CLIP-seq
MIRT1229389	hsa-miR-27a	CLIP-seq
MIRT1229390	hsa-miR-27b	CLIP-seq
MIRT1229391	hsa-miR-298	CLIP-seq
MIRT1229392	hsa-miR-300	CLIP-seq
MIRT2294732	hsa-miR-3117-3p	CLIP-seq
MIRT2294733	hsa-miR-3123	CLIP-seq
MIRT1229393	hsa-miR-3125	CLIP-seq
MIRT1229394	hsa-miR-3126-5p	CLIP-seq
MIRT2294734	hsa-miR-3130-3p	CLIP-seq
MIRT1229395	hsa-miR-3132	CLIP-seq
MIRT1229397	hsa-miR-3152-3p	CLIP-seq
MIRT2294735	hsa-miR-3154	CLIP-seq
MIRT2294736	hsa-miR-3157-5p	CLIP-seq
MIRT2294737	hsa-miR-3162-5p	CLIP-seq
MIRT2294738	hsa-miR-3165	CLIP-seq
MIRT1229398	hsa-miR-3183	CLIP-seq
MIRT2294739	hsa-miR-3193	CLIP-seq
MIRT1229399	hsa-miR-3200-5p	CLIP-seq
MIRT2294740	hsa-miR-320e	CLIP-seq
MIRT2294741	hsa-miR-324-3p	CLIP-seq
MIRT2294742	hsa-miR-329	CLIP-seq
MIRT2294743	hsa-miR-338-3p	CLIP-seq
MIRT1229400	hsa-miR-342-5p	CLIP-seq
MIRT2294744	hsa-miR-3614-5p	CLIP-seq
MIRT2294745	hsa-miR-3619-5p	CLIP-seq
MIRT2294746	hsa-miR-3622a-5p	CLIP-seq
MIRT2294747	hsa-miR-362-3p	CLIP-seq
MIRT1229403	hsa-miR-3653	CLIP-seq
MIRT1229404	hsa-miR-3658	CLIP-seq
MIRT2294748	hsa-miR-3667-3p	CLIP-seq
MIRT2294749	hsa-miR-3673	CLIP-seq
MIRT1229405	hsa-miR-3689d	CLIP-seq
MIRT2294750	hsa-miR-3691-3p	CLIP-seq
MIRT2294751	hsa-miR-377	CLIP-seq
MIRT1229406	hsa-miR-381	CLIP-seq
MIRT2294752	hsa-miR-3914	CLIP-seq
MIRT1229407	hsa-miR-3916	CLIP-seq
MIRT1229408	hsa-miR-421	CLIP-seq
MIRT2294753	hsa-miR-424	CLIP-seq
MIRT1229409	hsa-miR-4251	CLIP-seq
MIRT2294754	hsa-miR-4291	CLIP-seq
MIRT2067182	hsa-miR-4292	CLIP-seq
MIRT1229410	hsa-miR-4300	CLIP-seq
MIRT2294755	hsa-miR-4311	CLIP-seq
MIRT1229411	hsa-miR-4314	CLIP-seq
MIRT2294756	hsa-miR-4323	CLIP-seq
MIRT1229412	hsa-miR-4329	CLIP-seq
MIRT2294757	hsa-miR-4423-3p	CLIP-seq
MIRT2294758	hsa-miR-4436b-5p	CLIP-seq
MIRT1229413	hsa-miR-4447	CLIP-seq
MIRT1229414	hsa-miR-4451	CLIP-seq
MIRT2294759	hsa-miR-4465	CLIP-seq
MIRT1229415	hsa-miR-4468	CLIP-seq
MIRT1229416	hsa-miR-4472	CLIP-seq
MIRT1229417	hsa-miR-4476	CLIP-seq
MIRT2294760	hsa-miR-448	CLIP-seq
MIRT2294761	hsa-miR-4494	CLIP-seq
MIRT1229418	hsa-miR-4503	CLIP-seq
MIRT2067183	hsa-miR-4514	CLIP-seq
MIRT2294762	hsa-miR-4520a-5p	CLIP-seq
MIRT2294763	hsa-miR-4520b-5p	CLIP-seq
MIRT2294764	hsa-miR-4530	CLIP-seq
MIRT2294765	hsa-miR-4640-5p	CLIP-seq
MIRT1229420	hsa-miR-4643	CLIP-seq
MIRT1229422	hsa-miR-4650-5p	CLIP-seq
MIRT1229423	hsa-miR-4651	CLIP-seq
MIRT1229424	hsa-miR-466	CLIP-seq
MIRT1229425	hsa-miR-4664-5p	CLIP-seq
MIRT1229426	hsa-miR-4666-3p	CLIP-seq
MIRT1229427	hsa-miR-4667-5p	CLIP-seq
MIRT1229430	hsa-miR-4690-3p	CLIP-seq
MIRT2294766	hsa-miR-4690-5p	CLIP-seq
MIRT2067184	hsa-miR-4692	CLIP-seq
MIRT1229431	hsa-miR-4700-3p	CLIP-seq
MIRT1229432	hsa-miR-4700-5p	CLIP-seq
MIRT2294767	hsa-miR-4707-5p	CLIP-seq
MIRT1229433	hsa-miR-4709-5p	CLIP-seq
MIRT1229434	hsa-miR-4723-3p	CLIP-seq
MIRT1229435	hsa-miR-4724-3p	CLIP-seq
MIRT2067185	hsa-miR-4725-5p	CLIP-seq
MIRT2294768	hsa-miR-4726-5p	CLIP-seq
MIRT1229436	hsa-miR-4729	CLIP-seq
MIRT2294769	hsa-miR-4736	CLIP-seq
MIRT2294770	hsa-miR-4739	CLIP-seq
MIRT2294771	hsa-miR-4743	CLIP-seq
MIRT2294772	hsa-miR-4749-3p	CLIP-seq
MIRT2294773	hsa-miR-4756-5p	CLIP-seq
MIRT1229439	hsa-miR-4761-5p	CLIP-seq
MIRT2067186	hsa-miR-4763-3p	CLIP-seq
MIRT1229440	hsa-miR-4789-3p	CLIP-seq
MIRT1229441	hsa-miR-4789-5p	CLIP-seq
MIRT2294774	hsa-miR-4793-3p	CLIP-seq
MIRT2294775	hsa-miR-497	CLIP-seq
MIRT2294776	hsa-miR-499a-5p	CLIP-seq
MIRT2294777	hsa-miR-500a	CLIP-seq
MIRT2067187	hsa-miR-504	CLIP-seq
MIRT2294778	hsa-miR-508-5p	CLIP-seq
MIRT1229443	hsa-miR-513a-3p	CLIP-seq
MIRT1229444	hsa-miR-513a-5p	CLIP-seq
MIRT2294779	hsa-miR-548q	CLIP-seq
MIRT2294780	hsa-miR-583	CLIP-seq
MIRT2294781	hsa-miR-584	CLIP-seq
MIRT1229446	hsa-miR-608	CLIP-seq
MIRT1229447	hsa-miR-616	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT2294782	hsa-miR-651	CLIP-seq
MIRT1229449	hsa-miR-658	CLIP-seq
MIRT2294783	hsa-miR-761	CLIP-seq
MIRT2294784	hsa-miR-766	CLIP-seq
MIRT2294785	hsa-miR-873	CLIP-seq
MIRT2294786	hsa-miR-9	CLIP-seq
MIRT1229451	hsa-miR-920	CLIP-seq
MIRT2294787	hsa-miR-922	CLIP-seq
MIRT2067188	hsa-miR-940	CLIP-seq
MIRT2294788	hsa-miR-96	CLIP-seq
MIRT1229385	hsa-miR-128	CLIP-seq
MIRT1229387	hsa-miR-205	CLIP-seq
MIRT1229389	hsa-miR-27a	CLIP-seq
MIRT1229390	hsa-miR-27b	CLIP-seq
MIRT1229400	hsa-miR-342-5p	CLIP-seq
MIRT1229410	hsa-miR-4300	CLIP-seq
MIRT1229411	hsa-miR-4314	CLIP-seq
MIRT1229415	hsa-miR-4468	CLIP-seq
MIRT1229418	hsa-miR-4503	CLIP-seq
MIRT1229423	hsa-miR-4651	CLIP-seq
MIRT1229425	hsa-miR-4664-5p	CLIP-seq
MIRT1229427	hsa-miR-4667-5p	CLIP-seq
MIRT1229432	hsa-miR-4700-5p	CLIP-seq
MIRT1229443	hsa-miR-513a-3p	CLIP-seq
MIRT1229444	hsa-miR-513a-5p	CLIP-seq
MIRT1229446	hsa-miR-608	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT1229451	hsa-miR-920	CLIP-seq
MIRT2294705	hsa-miR-105	CLIP-seq
MIRT2294707	hsa-miR-1224-3p	CLIP-seq
MIRT1229386	hsa-miR-1284	CLIP-seq
MIRT2592547	hsa-miR-1302	CLIP-seq
MIRT2067180	hsa-miR-132	CLIP-seq
MIRT2294715	hsa-miR-1321	CLIP-seq
MIRT2294716	hsa-miR-138	CLIP-seq
MIRT2294720	hsa-miR-153	CLIP-seq
MIRT2294724	hsa-miR-182	CLIP-seq
MIRT2294728	hsa-miR-1972	CLIP-seq
MIRT2067181	hsa-miR-212	CLIP-seq
MIRT2294729	hsa-miR-214	CLIP-seq
MIRT1229392	hsa-miR-300	CLIP-seq
MIRT2294732	hsa-miR-3117-3p	CLIP-seq
MIRT2592548	hsa-miR-3122	CLIP-seq
MIRT2294737	hsa-miR-3162-5p	CLIP-seq
MIRT1229398	hsa-miR-3183	CLIP-seq
MIRT2294739	hsa-miR-3193	CLIP-seq
MIRT2592549	hsa-miR-320a	CLIP-seq
MIRT2592550	hsa-miR-320b	CLIP-seq
MIRT2592551	hsa-miR-320c	CLIP-seq
MIRT2592552	hsa-miR-320d	CLIP-seq
MIRT2294740	hsa-miR-320e	CLIP-seq
MIRT2294743	hsa-miR-338-3p	CLIP-seq
MIRT2294744	hsa-miR-3614-5p	CLIP-seq
MIRT2294745	hsa-miR-3619-5p	CLIP-seq
MIRT2294746	hsa-miR-3622a-5p	CLIP-seq
MIRT2592553	hsa-miR-3649	CLIP-seq
MIRT1229405	hsa-miR-3689d	CLIP-seq
MIRT2294750	hsa-miR-3691-3p	CLIP-seq
MIRT2294751	hsa-miR-377	CLIP-seq
MIRT1229406	hsa-miR-381	CLIP-seq
MIRT2592554	hsa-miR-3913-5p	CLIP-seq
MIRT1229408	hsa-miR-421	CLIP-seq
MIRT2067182	hsa-miR-4292	CLIP-seq
MIRT2592555	hsa-miR-4298	CLIP-seq
MIRT2294757	hsa-miR-4423-3p	CLIP-seq
MIRT2592556	hsa-miR-4429	CLIP-seq
MIRT2294760	hsa-miR-448	CLIP-seq
MIRT2294762	hsa-miR-4520a-5p	CLIP-seq
MIRT2294763	hsa-miR-4520b-5p	CLIP-seq
MIRT2294764	hsa-miR-4530	CLIP-seq
MIRT1229421	hsa-miR-4645-5p	CLIP-seq
MIRT1229422	hsa-miR-4650-5p	CLIP-seq
MIRT1229426	hsa-miR-4666-3p	CLIP-seq
MIRT1229428	hsa-miR-4673	CLIP-seq
MIRT2592557	hsa-miR-4688	CLIP-seq
MIRT2294766	hsa-miR-4690-5p	CLIP-seq
MIRT1229433	hsa-miR-4709-5p	CLIP-seq
MIRT1229434	hsa-miR-4723-3p	CLIP-seq
MIRT2067185	hsa-miR-4725-5p	CLIP-seq
MIRT2294770	hsa-miR-4739	CLIP-seq
MIRT2294771	hsa-miR-4743	CLIP-seq
MIRT1229438	hsa-miR-4746-5p	CLIP-seq
MIRT2294773	hsa-miR-4756-5p	CLIP-seq
MIRT2592558	hsa-miR-486-3p	CLIP-seq
MIRT2067187	hsa-miR-504	CLIP-seq
MIRT2294778	hsa-miR-508-5p	CLIP-seq
MIRT2294779	hsa-miR-548q	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT2294782	hsa-miR-651	CLIP-seq
MIRT2294783	hsa-miR-761	CLIP-seq
MIRT2294784	hsa-miR-766	CLIP-seq
MIRT2294705	hsa-miR-105	CLIP-seq
MIRT2294707	hsa-miR-1224-3p	CLIP-seq
MIRT2294711	hsa-miR-1261	CLIP-seq
MIRT1229386	hsa-miR-1284	CLIP-seq
MIRT2592547	hsa-miR-1302	CLIP-seq
MIRT2067180	hsa-miR-132	CLIP-seq
MIRT2294715	hsa-miR-1321	CLIP-seq
MIRT2294716	hsa-miR-138	CLIP-seq
MIRT2294720	hsa-miR-153	CLIP-seq
MIRT2294724	hsa-miR-182	CLIP-seq
MIRT2294728	hsa-miR-1972	CLIP-seq
MIRT2067181	hsa-miR-212	CLIP-seq
MIRT2294729	hsa-miR-214	CLIP-seq
MIRT1229392	hsa-miR-300	CLIP-seq
MIRT2294732	hsa-miR-3117-3p	CLIP-seq
MIRT2592548	hsa-miR-3122	CLIP-seq
MIRT2294737	hsa-miR-3162-5p	CLIP-seq
MIRT2294738	hsa-miR-3165	CLIP-seq
MIRT1229398	hsa-miR-3183	CLIP-seq
MIRT2294739	hsa-miR-3193	CLIP-seq
MIRT2592549	hsa-miR-320a	CLIP-seq
MIRT2592550	hsa-miR-320b	CLIP-seq
MIRT2592551	hsa-miR-320c	CLIP-seq
MIRT2592552	hsa-miR-320d	CLIP-seq
MIRT2294740	hsa-miR-320e	CLIP-seq
MIRT2294743	hsa-miR-338-3p	CLIP-seq
MIRT2294744	hsa-miR-3614-5p	CLIP-seq
MIRT2294745	hsa-miR-3619-5p	CLIP-seq
MIRT2294746	hsa-miR-3622a-5p	CLIP-seq
MIRT2592553	hsa-miR-3649	CLIP-seq
MIRT1229405	hsa-miR-3689d	CLIP-seq
MIRT2294750	hsa-miR-3691-3p	CLIP-seq
MIRT1229406	hsa-miR-381	CLIP-seq
MIRT2592554	hsa-miR-3913-5p	CLIP-seq
MIRT1229408	hsa-miR-421	CLIP-seq
MIRT2067182	hsa-miR-4292	CLIP-seq
MIRT2592555	hsa-miR-4298	CLIP-seq
MIRT2294757	hsa-miR-4423-3p	CLIP-seq
MIRT2592556	hsa-miR-4429	CLIP-seq
MIRT2294760	hsa-miR-448	CLIP-seq
MIRT2294762	hsa-miR-4520a-5p	CLIP-seq
MIRT2294763	hsa-miR-4520b-5p	CLIP-seq
MIRT2294764	hsa-miR-4530	CLIP-seq
MIRT1229421	hsa-miR-4645-5p	CLIP-seq
MIRT1229422	hsa-miR-4650-5p	CLIP-seq
MIRT1229426	hsa-miR-4666-3p	CLIP-seq
MIRT1229428	hsa-miR-4673	CLIP-seq
MIRT2592557	hsa-miR-4688	CLIP-seq
MIRT2294766	hsa-miR-4690-5p	CLIP-seq
MIRT1229433	hsa-miR-4709-5p	CLIP-seq
MIRT1229434	hsa-miR-4723-3p	CLIP-seq
MIRT2067185	hsa-miR-4725-5p	CLIP-seq
MIRT2294770	hsa-miR-4739	CLIP-seq
MIRT2294771	hsa-miR-4743	CLIP-seq
MIRT1229438	hsa-miR-4746-5p	CLIP-seq
MIRT2294773	hsa-miR-4756-5p	CLIP-seq
MIRT2592558	hsa-miR-486-3p	CLIP-seq
MIRT2067187	hsa-miR-504	CLIP-seq
MIRT2294778	hsa-miR-508-5p	CLIP-seq
MIRT2294779	hsa-miR-548q	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT2294782	hsa-miR-651	CLIP-seq
MIRT2294783	hsa-miR-761	CLIP-seq
MIRT2294784	hsa-miR-766	CLIP-seq

Show/Hide all (4)

Transcription factor	Regulation	Reference
HDAC1	Repression	21152868
HDAC2	Repression	21152868
STAT3	Unknown	17324931
VDR	Unknown	16849588;17207617

Show/Hide all (85)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	16964284
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0001649	Process	Osteoblast differentiation	HDA	16210410
GO:0001850	Function	Complement component C3a binding	IDA	17070910
GO:0001851	Function	Complement component C3b binding	IDA	17070910
GO:0002639	Process	Positive regulation of immunoglobulin production	IEA
GO:0002639	Process	Positive regulation of immunoglobulin production	ISS
GO:0003714	Function	Transcription corepressor activity	IDA	18487222
GO:0003714	Function	Transcription corepressor activity	IEA
GO:0005515	Function	Protein binding	IPI	11302691, 12065415, 16319068, 16964284, 19640993, 19906925, 20134482, 20195357, 20959514, 21746876, 24380853, 30021884, 30337686, 31522117, 31899195, 32296183
GO:0005634	Component	Nucleus	IDA	16964284, 20959514, 24732013, 31899195
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	16130169
GO:0005654	Component	Nucleoplasm	IDA	12466959
GO:0005737	Component	Cytoplasm	IDA	16964284, 31899195
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	HDA	20833797
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	24732013
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IDA	17008324, 18339324, 20959514, 28017329
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	TAS	14500729
GO:0005769	Component	Early endosome	IDA	24732013
GO:0005886	Component	Plasma membrane	IDA	15274632, 22997079, 24003225, 24732013
GO:0005886	Component	Plasma membrane	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IDA	14500729
GO:0007005	Process	Mitochondrion organization	IBA
GO:0007005	Process	Mitochondrion organization	IEA
GO:0007005	Process	Mitochondrion organization	IMP	17008324
GO:0007005	Process	Mitochondrion organization	NAS	18339324
GO:0007165	Process	Signal transduction	TAS	16130169
GO:0008285	Process	Negative regulation of cell population proliferation	IMP	18487222
GO:0009986	Component	Cell surface	IDA	22417827, 22997079, 24732013
GO:0009986	Component	Cell surface	IEA
GO:0010628	Process	Positive regulation of gene expression	IGI	26310625
GO:0010944	Process	Negative regulation of transcription by competitive promoter binding	IDA	18487222
GO:0016020	Component	Membrane	HDA	16210410, 19946888
GO:0016020	Component	Membrane	IEA
GO:0019899	Function	Enzyme binding	IPI	23921388
GO:0030308	Process	Negative regulation of cell growth	IMP	12065415
GO:0031871	Function	Proteinase activated receptor binding	IPI	24732013
GO:0032740	Process	Positive regulation of interleukin-17 production	IMP	31899195
GO:0035632	Component	Mitochondrial prohibitin complex	IDA	31522117
GO:0035632	Component	Mitochondrial prohibitin complex	IEA
GO:0035632	Component	Mitochondrial prohibitin complex	IPI	20959514
GO:0039529	Process	RIG-I signaling pathway	IDA	31522117
GO:0039529	Process	RIG-I signaling pathway	IEA
GO:0040029	Process	Epigenetic regulation of gene expression	IDA	12466959
GO:0042113	Process	B cell activation	IEA
GO:0042113	Process	B cell activation	ISS
GO:0042177	Process	Negative regulation of protein catabolic process	IMP	24732013
GO:0042826	Function	Histone deacetylase binding	IPI	16964284
GO:0042981	Process	Regulation of apoptotic process	TAS	16130169
GO:0043525	Process	Positive regulation of neuron apoptotic process	IGI	26310625
GO:0044830	Process	Host-mediated perturbation of viral RNA genome replication	IEA
GO:0044830	Process	Host-mediated perturbation of viral RNA genome replication	ISS
GO:0045745	Process	Positive regulation of G protein-coupled receptor signaling pathway	IMP	24732013
GO:0045892	Process	Negative regulation of DNA-templated transcription	IDA	12065415, 12566959
GO:0045892	Process	Negative regulation of DNA-templated transcription	IMP	18487222
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	14500729
GO:0045917	Process	Positive regulation of complement activation	IDA	17070910
GO:0046718	Process	Symbiont entry into host cell	IEA
GO:0046718	Process	Symbiont entry into host cell	ISS
GO:0046982	Function	Protein heterodimerization activity	IPI	28017329
GO:0048661	Process	Positive regulation of smooth muscle cell proliferation	ISS
GO:0050821	Process	Protein stabilization	IDA	18339324
GO:0050821	Process	Protein stabilization	IMP	17008324
GO:0050847	Process	Progesterone receptor signaling pathway	IDA	16964284
GO:0051897	Process	Positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ISS
GO:0060766	Process	Negative regulation of androgen receptor signaling pathway	IDA	16964284
GO:0060766	Process	Negative regulation of androgen receptor signaling pathway	IMP	18487222
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IMP	24732013
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	IMP	22417827
GO:0071354	Process	Cellular response to interleukin-6	IDA	17324931
GO:0071897	Process	DNA biosynthetic process	IEA
GO:0071897	Process	DNA biosynthetic process	IEA
GO:0072538	Process	T-helper 17 type immune response	IDA	31899195
GO:0140374	Process	Antiviral innate immune response	IDA	31522117
GO:0140374	Process	Antiviral innate immune response	IEA
GO:1901224	Process	Positive regulation of non-canonical NF-kappaB signal transduction	IEA
GO:1901224	Process	Positive regulation of non-canonical NF-kappaB signal transduction	ISS
GO:2000323	Process	Negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway	IDA	16964284

MIM	HGNC	e!Ensembl
176705	8912	ENSG00000167085

P35232

Protein name

Prohibitin 1

Protein function

Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription fac

PDB

8RRH

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01145	Band_7	28 → 210	SPFH domain / Band 7 family	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed in different tissues.

Sequence

MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ

Sequence length

272

Interactions

View interactions

	KEGG		Reactome
	Virion - Flavivirus and Alphavirus		RAF activation Signaling by moderate kinase activity BRAF mutants Paradoxical activation of RAF signaling by kinase inactive BRAF Processing of SMDT1 Signaling downstream of RAS mutants

Show/Hide Unknown Diseases (8)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Benign	rs2277637	RCV005937118
Breast cancer, susceptibility to	risk factor	rs112294663	RCV000014325
Familial cancer of breast	Benign	rs2233667	RCV005918614
Hepatocellular carcinoma	Benign	rs2233667	RCV005918615
Ovarian cancer	Benign	rs1229985221	RCV003154711
Ovarian serous cystadenocarcinoma	Benign	rs2277637	RCV005937120
PHB1-related disorder	Benign; Likely benign	rs2277637, rs530616891	RCV003979785 RCV003949611
Sarcoma	Benign	rs2277637	RCV005937119

PHB1 (prohibitin 1)