Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	5245
Gene name Gene Name - the full gene name approved by the HGNC.	Prohibitin 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PHB1
Synonyms (NCBI Gene) Gene synonyms aliases	BAP32, HEL-215, HEL-S-54e, PHB
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q21.33

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SNP ID	Visualize variation	Clinical significance	Consequence
rs112294663	G>A,C,T	Risk-factor	3 prime UTR variant

Show/Hide all(428)

miRTarBase ID	miRNA	Experiments	Reference
MIRT001210	hsa-miR-27a-3p	qRT-PCR, GFP reporter assay, Western blot	18789835
MIRT001210	hsa-miR-27a-3p	qRT-PCR, GFP reporter assay, Western blot	18789835
MIRT001210	hsa-miR-27a-3p	ChIP-seq, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	22505583
MIRT001210	hsa-miR-27a-3p	ChIP-seq, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	22505583
MIRT001210	hsa-miR-27a-3p	ChIP-seq, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	22505583
MIRT001210	hsa-miR-27a-3p	ChIP-seq, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	22505583
MIRT001210	hsa-miR-27a-3p	ChIP-seq, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	22505583
MIRT001210	hsa-miR-27a-3p	ChIP-seq, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	22505583
MIRT041678	hsa-miR-484	CLASH	23622248
MIRT438656	hsa-miR-26a-5p	Luciferase reporter assay, qRT-PCR, Western blot	23870455
MIRT438656	hsa-miR-26a-5p	Luciferase reporter assay, qRT-PCR, Western blot	23870455
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assay	24133204
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assay	24133204
MIRT438627	hsa-miR-27b-3p	Luciferase reporter assay	24133204
MIRT438627	hsa-miR-27b-3p	Luciferase reporter assay	24133204
MIRT438656	hsa-miR-26a-5p	Luciferase reporter assay, qRT-PCR, Western blot	23870455
MIRT438656	hsa-miR-26a-5p	Luciferase reporter assay, qRT-PCR, Western blot	23870455
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assay	24133204
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assay	24133204
MIRT438627	hsa-miR-27b-3p	Luciferase reporter assay	24133204
MIRT438627	hsa-miR-27b-3p	Luciferase reporter assay	24133204
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assay, Microarray, qRT-PCR	25915942
MIRT001210	hsa-miR-27a-3p	Luciferase reporter assay	25777779
MIRT1229383	hsa-miR-1252	CLIP-seq
MIRT1229384	hsa-miR-1264	CLIP-seq
MIRT1229385	hsa-miR-128	CLIP-seq
MIRT1229386	hsa-miR-1284	CLIP-seq
MIRT1229387	hsa-miR-205	CLIP-seq
MIRT1229388	hsa-miR-2277-3p	CLIP-seq
MIRT1229389	hsa-miR-27a	CLIP-seq
MIRT1229390	hsa-miR-27b	CLIP-seq
MIRT1229391	hsa-miR-298	CLIP-seq
MIRT1229392	hsa-miR-300	CLIP-seq
MIRT1229393	hsa-miR-3125	CLIP-seq
MIRT1229394	hsa-miR-3126-5p	CLIP-seq
MIRT1229395	hsa-miR-3132	CLIP-seq
MIRT1229396	hsa-miR-3136-3p	CLIP-seq
MIRT1229397	hsa-miR-3152-3p	CLIP-seq
MIRT1229398	hsa-miR-3183	CLIP-seq
MIRT1229399	hsa-miR-3200-5p	CLIP-seq
MIRT1229400	hsa-miR-342-5p	CLIP-seq
MIRT1229401	hsa-miR-3616-5p	CLIP-seq
MIRT1229402	hsa-miR-3647-5p	CLIP-seq
MIRT1229403	hsa-miR-3653	CLIP-seq
MIRT1229404	hsa-miR-3658	CLIP-seq
MIRT1229405	hsa-miR-3689d	CLIP-seq
MIRT1229406	hsa-miR-381	CLIP-seq
MIRT1229407	hsa-miR-3916	CLIP-seq
MIRT1229408	hsa-miR-421	CLIP-seq
MIRT1229409	hsa-miR-4251	CLIP-seq
MIRT1229410	hsa-miR-4300	CLIP-seq
MIRT1229411	hsa-miR-4314	CLIP-seq
MIRT1229412	hsa-miR-4329	CLIP-seq
MIRT1229413	hsa-miR-4447	CLIP-seq
MIRT1229414	hsa-miR-4451	CLIP-seq
MIRT1229415	hsa-miR-4468	CLIP-seq
MIRT1229416	hsa-miR-4472	CLIP-seq
MIRT1229417	hsa-miR-4476	CLIP-seq
MIRT1229418	hsa-miR-4503	CLIP-seq
MIRT1229419	hsa-miR-4508	CLIP-seq
MIRT1229420	hsa-miR-4643	CLIP-seq
MIRT1229421	hsa-miR-4645-5p	CLIP-seq
MIRT1229422	hsa-miR-4650-5p	CLIP-seq
MIRT1229423	hsa-miR-4651	CLIP-seq
MIRT1229424	hsa-miR-466	CLIP-seq
MIRT1229425	hsa-miR-4664-5p	CLIP-seq
MIRT1229426	hsa-miR-4666-3p	CLIP-seq
MIRT1229427	hsa-miR-4667-5p	CLIP-seq
MIRT1229428	hsa-miR-4673	CLIP-seq
MIRT1229429	hsa-miR-4675	CLIP-seq
MIRT1229430	hsa-miR-4690-3p	CLIP-seq
MIRT1229431	hsa-miR-4700-3p	CLIP-seq
MIRT1229432	hsa-miR-4700-5p	CLIP-seq
MIRT1229433	hsa-miR-4709-5p	CLIP-seq
MIRT1229434	hsa-miR-4723-3p	CLIP-seq
MIRT1229435	hsa-miR-4724-3p	CLIP-seq
MIRT1229436	hsa-miR-4729	CLIP-seq
MIRT1229437	hsa-miR-4741	CLIP-seq
MIRT1229438	hsa-miR-4746-5p	CLIP-seq
MIRT1229439	hsa-miR-4761-5p	CLIP-seq
MIRT1229440	hsa-miR-4789-3p	CLIP-seq
MIRT1229441	hsa-miR-4789-5p	CLIP-seq
MIRT1229442	hsa-miR-4795-5p	CLIP-seq
MIRT1229443	hsa-miR-513a-3p	CLIP-seq
MIRT1229444	hsa-miR-513a-5p	CLIP-seq
MIRT1229445	hsa-miR-573	CLIP-seq
MIRT1229446	hsa-miR-608	CLIP-seq
MIRT1229447	hsa-miR-616	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT1229449	hsa-miR-658	CLIP-seq
MIRT1229450	hsa-miR-663b	CLIP-seq
MIRT1229451	hsa-miR-920	CLIP-seq
MIRT2067179	hsa-miR-1207-5p	CLIP-seq
MIRT1229383	hsa-miR-1252	CLIP-seq
MIRT1229385	hsa-miR-128	CLIP-seq
MIRT2067180	hsa-miR-132	CLIP-seq
MIRT1229387	hsa-miR-205	CLIP-seq
MIRT2067181	hsa-miR-212	CLIP-seq
MIRT1229389	hsa-miR-27a	CLIP-seq
MIRT1229390	hsa-miR-27b	CLIP-seq
MIRT1229391	hsa-miR-298	CLIP-seq
MIRT1229397	hsa-miR-3152-3p	CLIP-seq
MIRT1229400	hsa-miR-342-5p	CLIP-seq
MIRT1229403	hsa-miR-3653	CLIP-seq
MIRT1229404	hsa-miR-3658	CLIP-seq
MIRT1229405	hsa-miR-3689d	CLIP-seq
MIRT2067182	hsa-miR-4292	CLIP-seq
MIRT1229410	hsa-miR-4300	CLIP-seq
MIRT1229411	hsa-miR-4314	CLIP-seq
MIRT1229415	hsa-miR-4468	CLIP-seq
MIRT1229417	hsa-miR-4476	CLIP-seq
MIRT1229418	hsa-miR-4503	CLIP-seq
MIRT2067183	hsa-miR-4514	CLIP-seq
MIRT1229423	hsa-miR-4651	CLIP-seq
MIRT1229425	hsa-miR-4664-5p	CLIP-seq
MIRT1229427	hsa-miR-4667-5p	CLIP-seq
MIRT1229430	hsa-miR-4690-3p	CLIP-seq
MIRT2067184	hsa-miR-4692	CLIP-seq
MIRT1229432	hsa-miR-4700-5p	CLIP-seq
MIRT1229433	hsa-miR-4709-5p	CLIP-seq
MIRT1229435	hsa-miR-4724-3p	CLIP-seq
MIRT2067185	hsa-miR-4725-5p	CLIP-seq
MIRT2067186	hsa-miR-4763-3p	CLIP-seq
MIRT2067187	hsa-miR-504	CLIP-seq
MIRT1229443	hsa-miR-513a-3p	CLIP-seq
MIRT1229444	hsa-miR-513a-5p	CLIP-seq
MIRT1229446	hsa-miR-608	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT1229449	hsa-miR-658	CLIP-seq
MIRT1229451	hsa-miR-920	CLIP-seq
MIRT2067188	hsa-miR-940	CLIP-seq
MIRT2294704	hsa-miR-103a	CLIP-seq
MIRT2294705	hsa-miR-105	CLIP-seq
MIRT2294706	hsa-miR-107	CLIP-seq
MIRT2067179	hsa-miR-1207-5p	CLIP-seq
MIRT2294707	hsa-miR-1224-3p	CLIP-seq
MIRT2294708	hsa-miR-1228	CLIP-seq
MIRT2294709	hsa-miR-1236	CLIP-seq
MIRT1229383	hsa-miR-1252	CLIP-seq
MIRT2294710	hsa-miR-1253	CLIP-seq
MIRT2294711	hsa-miR-1261	CLIP-seq
MIRT1229384	hsa-miR-1264	CLIP-seq
MIRT2294712	hsa-miR-1271	CLIP-seq
MIRT2294713	hsa-miR-1276	CLIP-seq
MIRT1229385	hsa-miR-128	CLIP-seq
MIRT1229386	hsa-miR-1284	CLIP-seq
MIRT2294714	hsa-miR-1297	CLIP-seq
MIRT2067180	hsa-miR-132	CLIP-seq
MIRT2294715	hsa-miR-1321	CLIP-seq
MIRT2294716	hsa-miR-138	CLIP-seq
MIRT2294717	hsa-miR-148a	CLIP-seq
MIRT2294718	hsa-miR-148b	CLIP-seq
MIRT2294719	hsa-miR-152	CLIP-seq
MIRT2294720	hsa-miR-153	CLIP-seq
MIRT2294721	hsa-miR-15a	CLIP-seq
MIRT2294722	hsa-miR-15b	CLIP-seq
MIRT2294723	hsa-miR-16	CLIP-seq
MIRT2294724	hsa-miR-182	CLIP-seq
MIRT2294725	hsa-miR-1825	CLIP-seq
MIRT2294726	hsa-miR-1913	CLIP-seq
MIRT2294727	hsa-miR-195	CLIP-seq
MIRT2294728	hsa-miR-1972	CLIP-seq
MIRT1229387	hsa-miR-205	CLIP-seq
MIRT2067181	hsa-miR-212	CLIP-seq
MIRT2294729	hsa-miR-214	CLIP-seq
MIRT1229388	hsa-miR-2277-3p	CLIP-seq
MIRT2294730	hsa-miR-26a	CLIP-seq
MIRT2294731	hsa-miR-26b	CLIP-seq
MIRT1229389	hsa-miR-27a	CLIP-seq
MIRT1229390	hsa-miR-27b	CLIP-seq
MIRT1229391	hsa-miR-298	CLIP-seq
MIRT1229392	hsa-miR-300	CLIP-seq
MIRT2294732	hsa-miR-3117-3p	CLIP-seq
MIRT2294733	hsa-miR-3123	CLIP-seq
MIRT1229393	hsa-miR-3125	CLIP-seq
MIRT1229394	hsa-miR-3126-5p	CLIP-seq
MIRT2294734	hsa-miR-3130-3p	CLIP-seq
MIRT1229395	hsa-miR-3132	CLIP-seq
MIRT1229397	hsa-miR-3152-3p	CLIP-seq
MIRT2294735	hsa-miR-3154	CLIP-seq
MIRT2294736	hsa-miR-3157-5p	CLIP-seq
MIRT2294737	hsa-miR-3162-5p	CLIP-seq
MIRT2294738	hsa-miR-3165	CLIP-seq
MIRT1229398	hsa-miR-3183	CLIP-seq
MIRT2294739	hsa-miR-3193	CLIP-seq
MIRT1229399	hsa-miR-3200-5p	CLIP-seq
MIRT2294740	hsa-miR-320e	CLIP-seq
MIRT2294741	hsa-miR-324-3p	CLIP-seq
MIRT2294742	hsa-miR-329	CLIP-seq
MIRT2294743	hsa-miR-338-3p	CLIP-seq
MIRT1229400	hsa-miR-342-5p	CLIP-seq
MIRT2294744	hsa-miR-3614-5p	CLIP-seq
MIRT2294745	hsa-miR-3619-5p	CLIP-seq
MIRT2294746	hsa-miR-3622a-5p	CLIP-seq
MIRT2294747	hsa-miR-362-3p	CLIP-seq
MIRT1229403	hsa-miR-3653	CLIP-seq
MIRT1229404	hsa-miR-3658	CLIP-seq
MIRT2294748	hsa-miR-3667-3p	CLIP-seq
MIRT2294749	hsa-miR-3673	CLIP-seq
MIRT1229405	hsa-miR-3689d	CLIP-seq
MIRT2294750	hsa-miR-3691-3p	CLIP-seq
MIRT2294751	hsa-miR-377	CLIP-seq
MIRT1229406	hsa-miR-381	CLIP-seq
MIRT2294752	hsa-miR-3914	CLIP-seq
MIRT1229407	hsa-miR-3916	CLIP-seq
MIRT1229408	hsa-miR-421	CLIP-seq
MIRT2294753	hsa-miR-424	CLIP-seq
MIRT1229409	hsa-miR-4251	CLIP-seq
MIRT2294754	hsa-miR-4291	CLIP-seq
MIRT2067182	hsa-miR-4292	CLIP-seq
MIRT1229410	hsa-miR-4300	CLIP-seq
MIRT2294755	hsa-miR-4311	CLIP-seq
MIRT1229411	hsa-miR-4314	CLIP-seq
MIRT2294756	hsa-miR-4323	CLIP-seq
MIRT1229412	hsa-miR-4329	CLIP-seq
MIRT2294757	hsa-miR-4423-3p	CLIP-seq
MIRT2294758	hsa-miR-4436b-5p	CLIP-seq
MIRT1229413	hsa-miR-4447	CLIP-seq
MIRT1229414	hsa-miR-4451	CLIP-seq
MIRT2294759	hsa-miR-4465	CLIP-seq
MIRT1229415	hsa-miR-4468	CLIP-seq
MIRT1229416	hsa-miR-4472	CLIP-seq
MIRT1229417	hsa-miR-4476	CLIP-seq
MIRT2294760	hsa-miR-448	CLIP-seq
MIRT2294761	hsa-miR-4494	CLIP-seq
MIRT1229418	hsa-miR-4503	CLIP-seq
MIRT2067183	hsa-miR-4514	CLIP-seq
MIRT2294762	hsa-miR-4520a-5p	CLIP-seq
MIRT2294763	hsa-miR-4520b-5p	CLIP-seq
MIRT2294764	hsa-miR-4530	CLIP-seq
MIRT2294765	hsa-miR-4640-5p	CLIP-seq
MIRT1229420	hsa-miR-4643	CLIP-seq
MIRT1229422	hsa-miR-4650-5p	CLIP-seq
MIRT1229423	hsa-miR-4651	CLIP-seq
MIRT1229424	hsa-miR-466	CLIP-seq
MIRT1229425	hsa-miR-4664-5p	CLIP-seq
MIRT1229426	hsa-miR-4666-3p	CLIP-seq
MIRT1229427	hsa-miR-4667-5p	CLIP-seq
MIRT1229430	hsa-miR-4690-3p	CLIP-seq
MIRT2294766	hsa-miR-4690-5p	CLIP-seq
MIRT2067184	hsa-miR-4692	CLIP-seq
MIRT1229431	hsa-miR-4700-3p	CLIP-seq
MIRT1229432	hsa-miR-4700-5p	CLIP-seq
MIRT2294767	hsa-miR-4707-5p	CLIP-seq
MIRT1229433	hsa-miR-4709-5p	CLIP-seq
MIRT1229434	hsa-miR-4723-3p	CLIP-seq
MIRT1229435	hsa-miR-4724-3p	CLIP-seq
MIRT2067185	hsa-miR-4725-5p	CLIP-seq
MIRT2294768	hsa-miR-4726-5p	CLIP-seq
MIRT1229436	hsa-miR-4729	CLIP-seq
MIRT2294769	hsa-miR-4736	CLIP-seq
MIRT2294770	hsa-miR-4739	CLIP-seq
MIRT2294771	hsa-miR-4743	CLIP-seq
MIRT2294772	hsa-miR-4749-3p	CLIP-seq
MIRT2294773	hsa-miR-4756-5p	CLIP-seq
MIRT1229439	hsa-miR-4761-5p	CLIP-seq
MIRT2067186	hsa-miR-4763-3p	CLIP-seq
MIRT1229440	hsa-miR-4789-3p	CLIP-seq
MIRT1229441	hsa-miR-4789-5p	CLIP-seq
MIRT2294774	hsa-miR-4793-3p	CLIP-seq
MIRT2294775	hsa-miR-497	CLIP-seq
MIRT2294776	hsa-miR-499a-5p	CLIP-seq
MIRT2294777	hsa-miR-500a	CLIP-seq
MIRT2067187	hsa-miR-504	CLIP-seq
MIRT2294778	hsa-miR-508-5p	CLIP-seq
MIRT1229443	hsa-miR-513a-3p	CLIP-seq
MIRT1229444	hsa-miR-513a-5p	CLIP-seq
MIRT2294779	hsa-miR-548q	CLIP-seq
MIRT2294780	hsa-miR-583	CLIP-seq
MIRT2294781	hsa-miR-584	CLIP-seq
MIRT1229446	hsa-miR-608	CLIP-seq
MIRT1229447	hsa-miR-616	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT2294782	hsa-miR-651	CLIP-seq
MIRT1229449	hsa-miR-658	CLIP-seq
MIRT2294783	hsa-miR-761	CLIP-seq
MIRT2294784	hsa-miR-766	CLIP-seq
MIRT2294785	hsa-miR-873	CLIP-seq
MIRT2294786	hsa-miR-9	CLIP-seq
MIRT1229451	hsa-miR-920	CLIP-seq
MIRT2294787	hsa-miR-922	CLIP-seq
MIRT2067188	hsa-miR-940	CLIP-seq
MIRT2294788	hsa-miR-96	CLIP-seq
MIRT1229385	hsa-miR-128	CLIP-seq
MIRT1229387	hsa-miR-205	CLIP-seq
MIRT1229389	hsa-miR-27a	CLIP-seq
MIRT1229390	hsa-miR-27b	CLIP-seq
MIRT1229400	hsa-miR-342-5p	CLIP-seq
MIRT1229410	hsa-miR-4300	CLIP-seq
MIRT1229411	hsa-miR-4314	CLIP-seq
MIRT1229415	hsa-miR-4468	CLIP-seq
MIRT1229418	hsa-miR-4503	CLIP-seq
MIRT1229423	hsa-miR-4651	CLIP-seq
MIRT1229425	hsa-miR-4664-5p	CLIP-seq
MIRT1229427	hsa-miR-4667-5p	CLIP-seq
MIRT1229432	hsa-miR-4700-5p	CLIP-seq
MIRT1229443	hsa-miR-513a-3p	CLIP-seq
MIRT1229444	hsa-miR-513a-5p	CLIP-seq
MIRT1229446	hsa-miR-608	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT1229451	hsa-miR-920	CLIP-seq
MIRT2294705	hsa-miR-105	CLIP-seq
MIRT2294707	hsa-miR-1224-3p	CLIP-seq
MIRT1229386	hsa-miR-1284	CLIP-seq
MIRT2592547	hsa-miR-1302	CLIP-seq
MIRT2067180	hsa-miR-132	CLIP-seq
MIRT2294715	hsa-miR-1321	CLIP-seq
MIRT2294716	hsa-miR-138	CLIP-seq
MIRT2294720	hsa-miR-153	CLIP-seq
MIRT2294724	hsa-miR-182	CLIP-seq
MIRT2294728	hsa-miR-1972	CLIP-seq
MIRT2067181	hsa-miR-212	CLIP-seq
MIRT2294729	hsa-miR-214	CLIP-seq
MIRT1229392	hsa-miR-300	CLIP-seq
MIRT2294732	hsa-miR-3117-3p	CLIP-seq
MIRT2592548	hsa-miR-3122	CLIP-seq
MIRT2294737	hsa-miR-3162-5p	CLIP-seq
MIRT1229398	hsa-miR-3183	CLIP-seq
MIRT2294739	hsa-miR-3193	CLIP-seq
MIRT2592549	hsa-miR-320a	CLIP-seq
MIRT2592550	hsa-miR-320b	CLIP-seq
MIRT2592551	hsa-miR-320c	CLIP-seq
MIRT2592552	hsa-miR-320d	CLIP-seq
MIRT2294740	hsa-miR-320e	CLIP-seq
MIRT2294743	hsa-miR-338-3p	CLIP-seq
MIRT2294744	hsa-miR-3614-5p	CLIP-seq
MIRT2294745	hsa-miR-3619-5p	CLIP-seq
MIRT2294746	hsa-miR-3622a-5p	CLIP-seq
MIRT2592553	hsa-miR-3649	CLIP-seq
MIRT1229405	hsa-miR-3689d	CLIP-seq
MIRT2294750	hsa-miR-3691-3p	CLIP-seq
MIRT2294751	hsa-miR-377	CLIP-seq
MIRT1229406	hsa-miR-381	CLIP-seq
MIRT2592554	hsa-miR-3913-5p	CLIP-seq
MIRT1229408	hsa-miR-421	CLIP-seq
MIRT2067182	hsa-miR-4292	CLIP-seq
MIRT2592555	hsa-miR-4298	CLIP-seq
MIRT2294757	hsa-miR-4423-3p	CLIP-seq
MIRT2592556	hsa-miR-4429	CLIP-seq
MIRT2294760	hsa-miR-448	CLIP-seq
MIRT2294762	hsa-miR-4520a-5p	CLIP-seq
MIRT2294763	hsa-miR-4520b-5p	CLIP-seq
MIRT2294764	hsa-miR-4530	CLIP-seq
MIRT1229421	hsa-miR-4645-5p	CLIP-seq
MIRT1229422	hsa-miR-4650-5p	CLIP-seq
MIRT1229426	hsa-miR-4666-3p	CLIP-seq
MIRT1229428	hsa-miR-4673	CLIP-seq
MIRT2592557	hsa-miR-4688	CLIP-seq
MIRT2294766	hsa-miR-4690-5p	CLIP-seq
MIRT1229433	hsa-miR-4709-5p	CLIP-seq
MIRT1229434	hsa-miR-4723-3p	CLIP-seq
MIRT2067185	hsa-miR-4725-5p	CLIP-seq
MIRT2294770	hsa-miR-4739	CLIP-seq
MIRT2294771	hsa-miR-4743	CLIP-seq
MIRT1229438	hsa-miR-4746-5p	CLIP-seq
MIRT2294773	hsa-miR-4756-5p	CLIP-seq
MIRT2592558	hsa-miR-486-3p	CLIP-seq
MIRT2067187	hsa-miR-504	CLIP-seq
MIRT2294778	hsa-miR-508-5p	CLIP-seq
MIRT2294779	hsa-miR-548q	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT2294782	hsa-miR-651	CLIP-seq
MIRT2294783	hsa-miR-761	CLIP-seq
MIRT2294784	hsa-miR-766	CLIP-seq
MIRT2294705	hsa-miR-105	CLIP-seq
MIRT2294707	hsa-miR-1224-3p	CLIP-seq
MIRT2294711	hsa-miR-1261	CLIP-seq
MIRT1229386	hsa-miR-1284	CLIP-seq
MIRT2592547	hsa-miR-1302	CLIP-seq
MIRT2067180	hsa-miR-132	CLIP-seq
MIRT2294715	hsa-miR-1321	CLIP-seq
MIRT2294716	hsa-miR-138	CLIP-seq
MIRT2294720	hsa-miR-153	CLIP-seq
MIRT2294724	hsa-miR-182	CLIP-seq
MIRT2294728	hsa-miR-1972	CLIP-seq
MIRT2067181	hsa-miR-212	CLIP-seq
MIRT2294729	hsa-miR-214	CLIP-seq
MIRT1229392	hsa-miR-300	CLIP-seq
MIRT2294732	hsa-miR-3117-3p	CLIP-seq
MIRT2592548	hsa-miR-3122	CLIP-seq
MIRT2294737	hsa-miR-3162-5p	CLIP-seq
MIRT2294738	hsa-miR-3165	CLIP-seq
MIRT1229398	hsa-miR-3183	CLIP-seq
MIRT2294739	hsa-miR-3193	CLIP-seq
MIRT2592549	hsa-miR-320a	CLIP-seq
MIRT2592550	hsa-miR-320b	CLIP-seq
MIRT2592551	hsa-miR-320c	CLIP-seq
MIRT2592552	hsa-miR-320d	CLIP-seq
MIRT2294740	hsa-miR-320e	CLIP-seq
MIRT2294743	hsa-miR-338-3p	CLIP-seq
MIRT2294744	hsa-miR-3614-5p	CLIP-seq
MIRT2294745	hsa-miR-3619-5p	CLIP-seq
MIRT2294746	hsa-miR-3622a-5p	CLIP-seq
MIRT2592553	hsa-miR-3649	CLIP-seq
MIRT1229405	hsa-miR-3689d	CLIP-seq
MIRT2294750	hsa-miR-3691-3p	CLIP-seq
MIRT1229406	hsa-miR-381	CLIP-seq
MIRT2592554	hsa-miR-3913-5p	CLIP-seq
MIRT1229408	hsa-miR-421	CLIP-seq
MIRT2067182	hsa-miR-4292	CLIP-seq
MIRT2592555	hsa-miR-4298	CLIP-seq
MIRT2294757	hsa-miR-4423-3p	CLIP-seq
MIRT2592556	hsa-miR-4429	CLIP-seq
MIRT2294760	hsa-miR-448	CLIP-seq
MIRT2294762	hsa-miR-4520a-5p	CLIP-seq
MIRT2294763	hsa-miR-4520b-5p	CLIP-seq
MIRT2294764	hsa-miR-4530	CLIP-seq
MIRT1229421	hsa-miR-4645-5p	CLIP-seq
MIRT1229422	hsa-miR-4650-5p	CLIP-seq
MIRT1229426	hsa-miR-4666-3p	CLIP-seq
MIRT1229428	hsa-miR-4673	CLIP-seq
MIRT2592557	hsa-miR-4688	CLIP-seq
MIRT2294766	hsa-miR-4690-5p	CLIP-seq
MIRT1229433	hsa-miR-4709-5p	CLIP-seq
MIRT1229434	hsa-miR-4723-3p	CLIP-seq
MIRT2067185	hsa-miR-4725-5p	CLIP-seq
MIRT2294770	hsa-miR-4739	CLIP-seq
MIRT2294771	hsa-miR-4743	CLIP-seq
MIRT1229438	hsa-miR-4746-5p	CLIP-seq
MIRT2294773	hsa-miR-4756-5p	CLIP-seq
MIRT2592558	hsa-miR-486-3p	CLIP-seq
MIRT2067187	hsa-miR-504	CLIP-seq
MIRT2294778	hsa-miR-508-5p	CLIP-seq
MIRT2294779	hsa-miR-548q	CLIP-seq
MIRT1229448	hsa-miR-637	CLIP-seq
MIRT2294782	hsa-miR-651	CLIP-seq
MIRT2294783	hsa-miR-761	CLIP-seq
MIRT2294784	hsa-miR-766	CLIP-seq

Transcription factors

Show/Hide all(4)

Transcription factor	Regulation	Reference
HDAC1	Repression	21152868
HDAC2	Repression	21152868
STAT3	Unknown	17324931
VDR	Unknown	16849588;17207617

Show/Hide all(85)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	16964284
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0001649	Process	Osteoblast differentiation	HDA	16210410
GO:0001850	Function	Complement component C3a binding	IDA	17070910
GO:0001851	Function	Complement component C3b binding	IDA	17070910
GO:0002639	Process	Positive regulation of immunoglobulin production	IEA
GO:0002639	Process	Positive regulation of immunoglobulin production	ISS
GO:0003714	Function	Transcription corepressor activity	IDA	18487222
GO:0003714	Function	Transcription corepressor activity	IEA
GO:0005515	Function	Protein binding	IPI	11302691, 12065415, 16319068, 16964284, 19640993, 19906925, 20134482, 20195357, 20959514, 21746876, 24380853, 30021884, 30337686, 31522117, 31899195, 32296183
GO:0005634	Component	Nucleus	IDA	16964284, 20959514, 24732013, 31899195
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	16130169
GO:0005654	Component	Nucleoplasm	IDA	12466959
GO:0005737	Component	Cytoplasm	IDA	16964284, 31899195
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	HDA	20833797
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	24732013
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IDA	17008324, 18339324, 20959514, 28017329
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	TAS	14500729
GO:0005769	Component	Early endosome	IDA	24732013
GO:0005886	Component	Plasma membrane	IDA	15274632, 22997079, 24003225, 24732013
GO:0005886	Component	Plasma membrane	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IDA	14500729
GO:0007005	Process	Mitochondrion organization	IBA
GO:0007005	Process	Mitochondrion organization	IEA
GO:0007005	Process	Mitochondrion organization	IMP	17008324
GO:0007005	Process	Mitochondrion organization	NAS	18339324
GO:0007165	Process	Signal transduction	TAS	16130169
GO:0008285	Process	Negative regulation of cell population proliferation	IMP	18487222
GO:0009986	Component	Cell surface	IDA	22417827, 22997079, 24732013
GO:0009986	Component	Cell surface	IEA
GO:0010628	Process	Positive regulation of gene expression	IGI	26310625
GO:0010944	Process	Negative regulation of transcription by competitive promoter binding	IDA	18487222
GO:0016020	Component	Membrane	HDA	16210410, 19946888
GO:0016020	Component	Membrane	IEA
GO:0019899	Function	Enzyme binding	IPI	23921388
GO:0030308	Process	Negative regulation of cell growth	IMP	12065415
GO:0031871	Function	Proteinase activated receptor binding	IPI	24732013
GO:0032740	Process	Positive regulation of interleukin-17 production	IMP	31899195
GO:0035632	Component	Mitochondrial prohibitin complex	IDA	31522117
GO:0035632	Component	Mitochondrial prohibitin complex	IEA
GO:0035632	Component	Mitochondrial prohibitin complex	IPI	20959514
GO:0039529	Process	RIG-I signaling pathway	IDA	31522117
GO:0039529	Process	RIG-I signaling pathway	IEA
GO:0040029	Process	Epigenetic regulation of gene expression	IDA	12466959
GO:0042113	Process	B cell activation	IEA
GO:0042113	Process	B cell activation	ISS
GO:0042177	Process	Negative regulation of protein catabolic process	IMP	24732013
GO:0042826	Function	Histone deacetylase binding	IPI	16964284
GO:0042981	Process	Regulation of apoptotic process	TAS	16130169
GO:0043525	Process	Positive regulation of neuron apoptotic process	IGI	26310625
GO:0044830	Process	Host-mediated perturbation of viral RNA genome replication	IEA
GO:0044830	Process	Host-mediated perturbation of viral RNA genome replication	ISS
GO:0045745	Process	Positive regulation of G protein-coupled receptor signaling pathway	IMP	24732013
GO:0045892	Process	Negative regulation of DNA-templated transcription	IDA	12065415, 12566959
GO:0045892	Process	Negative regulation of DNA-templated transcription	IMP	18487222
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	14500729
GO:0045917	Process	Positive regulation of complement activation	IDA	17070910
GO:0046718	Process	Symbiont entry into host cell	IEA
GO:0046718	Process	Symbiont entry into host cell	ISS
GO:0046982	Function	Protein heterodimerization activity	IPI	28017329
GO:0048661	Process	Positive regulation of smooth muscle cell proliferation	ISS
GO:0050821	Process	Protein stabilization	IDA	18339324
GO:0050821	Process	Protein stabilization	IMP	17008324
GO:0050847	Process	Progesterone receptor signaling pathway	IDA	16964284
GO:0051897	Process	Positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ISS
GO:0060766	Process	Negative regulation of androgen receptor signaling pathway	IDA	16964284
GO:0060766	Process	Negative regulation of androgen receptor signaling pathway	IMP	18487222
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IMP	24732013
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	IMP	22417827
GO:0071354	Process	Cellular response to interleukin-6	IDA	17324931
GO:0071897	Process	DNA biosynthetic process	IEA
GO:0071897	Process	DNA biosynthetic process	IEA
GO:0072538	Process	T-helper 17 type immune response	IDA	31899195
GO:0140374	Process	Antiviral innate immune response	IDA	31522117
GO:0140374	Process	Antiviral innate immune response	IEA
GO:1901224	Process	Positive regulation of non-canonical NF-kappaB signal transduction	IEA
GO:1901224	Process	Positive regulation of non-canonical NF-kappaB signal transduction	ISS
GO:2000323	Process	Negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway	IDA	16964284

MIM	HGNC	e!Ensembl
176705	8912	ENSG00000167085

Protein

UniProt ID

P35232

Protein name

Prohibitin 1

Protein function

Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription fac

PDB

8RRH

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01145	Band_7	28 → 210	SPFH domain / Band 7 family	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed in different tissues.

Sequence

MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW
VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLP
SITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFT
EAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRK
LEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ

Sequence length

272

Interactions

View interactions

	KEGG		Reactome
	Virion - Flavivirus and Alphavirus		RAF activation Signaling by moderate kinase activity BRAF mutants Paradoxical activation of RAF signaling by kinase inactive BRAF Processing of SMDT1 Signaling downstream of RAS mutants

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Coronary artery disease	Coronary artery disease	N/A	N/A	GWAS

PHB1 (prohibitin 1)