Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	5239
Gene name	Phosphoglucomutase 5
Gene symbol	PGM5
Synonyms (NCBI Gene)	PGMRP
Chromosome	9
Chromosome location	9q21.11
Summary	Phosphoglucomutases (EC 5.2.2.2.), such as PGM5, are phosphotransferases involved in interconversion of glucose-1-phosphate and glucose-6-phosphate. PGM activity is essential in formation of carbohydrates from glucose-6-phosphate and in formation of gluco

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miRTarBase ID	miRNA	Experiments	Reference
MIRT017304	hsa-miR-335-5p	Microarray	18185580
MIRT022385	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT1227917	hsa-miR-106a	CLIP-seq
MIRT1227918	hsa-miR-106b	CLIP-seq
MIRT1227919	hsa-miR-1207-5p	CLIP-seq
MIRT1227920	hsa-miR-1229	CLIP-seq
MIRT1227921	hsa-miR-1271	CLIP-seq
MIRT1227922	hsa-miR-1301	CLIP-seq
MIRT1227923	hsa-miR-132	CLIP-seq
MIRT1227924	hsa-miR-17	CLIP-seq
MIRT1227925	hsa-miR-20a	CLIP-seq
MIRT1227926	hsa-miR-20b	CLIP-seq
MIRT1227927	hsa-miR-212	CLIP-seq
MIRT1227928	hsa-miR-3125	CLIP-seq
MIRT1227929	hsa-miR-3187-3p	CLIP-seq
MIRT1227930	hsa-miR-3614-5p	CLIP-seq
MIRT1227931	hsa-miR-3916	CLIP-seq
MIRT1227932	hsa-miR-3973	CLIP-seq
MIRT1227933	hsa-miR-4289	CLIP-seq
MIRT1227934	hsa-miR-4435	CLIP-seq
MIRT1227935	hsa-miR-4484	CLIP-seq
MIRT1227936	hsa-miR-4509	CLIP-seq
MIRT1227937	hsa-miR-4660	CLIP-seq
MIRT1227938	hsa-miR-4701-5p	CLIP-seq
MIRT1227939	hsa-miR-4720-3p	CLIP-seq
MIRT1227940	hsa-miR-4733-3p	CLIP-seq
MIRT1227941	hsa-miR-4736	CLIP-seq
MIRT1227942	hsa-miR-4763-3p	CLIP-seq
MIRT1227943	hsa-miR-4765	CLIP-seq
MIRT1227944	hsa-miR-4804-3p	CLIP-seq
MIRT1227945	hsa-miR-5047	CLIP-seq
MIRT1227946	hsa-miR-519a	CLIP-seq
MIRT1227947	hsa-miR-519b-3p	CLIP-seq
MIRT1227948	hsa-miR-519c-3p	CLIP-seq
MIRT1227949	hsa-miR-519d	CLIP-seq
MIRT1227950	hsa-miR-520g	CLIP-seq
MIRT1227951	hsa-miR-520h	CLIP-seq
MIRT1227952	hsa-miR-548an	CLIP-seq
MIRT1227953	hsa-miR-548s	CLIP-seq
MIRT1227954	hsa-miR-549	CLIP-seq
MIRT1227955	hsa-miR-570	CLIP-seq
MIRT1227956	hsa-miR-576-3p	CLIP-seq
MIRT1227957	hsa-miR-588	CLIP-seq
MIRT1227958	hsa-miR-718	CLIP-seq
MIRT1227959	hsa-miR-767-5p	CLIP-seq
MIRT1227960	hsa-miR-93	CLIP-seq
MIRT1227961	hsa-miR-96	CLIP-seq
MIRT1227919	hsa-miR-1207-5p	CLIP-seq
MIRT1227920	hsa-miR-1229	CLIP-seq
MIRT1227930	hsa-miR-3614-5p	CLIP-seq
MIRT2066698	hsa-miR-4446-5p	CLIP-seq
MIRT1227942	hsa-miR-4763-3p	CLIP-seq
MIRT1227919	hsa-miR-1207-5p	CLIP-seq
MIRT2294324	hsa-miR-1275	CLIP-seq
MIRT2294325	hsa-miR-1294	CLIP-seq
MIRT1227922	hsa-miR-1301	CLIP-seq
MIRT2294326	hsa-miR-1827	CLIP-seq
MIRT2294327	hsa-miR-2110	CLIP-seq
MIRT2294328	hsa-miR-3147	CLIP-seq
MIRT2294329	hsa-miR-3150a-3p	CLIP-seq
MIRT2294330	hsa-miR-3612	CLIP-seq
MIRT2294331	hsa-miR-4286	CLIP-seq
MIRT2294332	hsa-miR-4327	CLIP-seq
MIRT2294333	hsa-miR-4425	CLIP-seq
MIRT2294334	hsa-miR-4450	CLIP-seq
MIRT2294335	hsa-miR-450b-5p	CLIP-seq
MIRT2294336	hsa-miR-4525	CLIP-seq
MIRT2294337	hsa-miR-4665-5p	CLIP-seq
MIRT2294338	hsa-miR-4723-5p	CLIP-seq
MIRT1227942	hsa-miR-4763-3p	CLIP-seq
MIRT1227945	hsa-miR-5047	CLIP-seq
MIRT2294339	hsa-miR-507	CLIP-seq
MIRT2294340	hsa-miR-520d-5p	CLIP-seq
MIRT2294341	hsa-miR-524-5p	CLIP-seq
MIRT2294342	hsa-miR-557	CLIP-seq
MIRT2294343	hsa-miR-625	CLIP-seq
MIRT2294344	hsa-miR-650	CLIP-seq
MIRT2294345	hsa-miR-940	CLIP-seq
MIRT2294324	hsa-miR-1275	CLIP-seq
MIRT2456297	hsa-miR-200b	CLIP-seq
MIRT2456298	hsa-miR-200c	CLIP-seq
MIRT2294327	hsa-miR-2110	CLIP-seq
MIRT2294328	hsa-miR-3147	CLIP-seq
MIRT2294329	hsa-miR-3150a-3p	CLIP-seq
MIRT2456299	hsa-miR-369-3p	CLIP-seq
MIRT2456300	hsa-miR-429	CLIP-seq
MIRT2294333	hsa-miR-4425	CLIP-seq
MIRT2294334	hsa-miR-4450	CLIP-seq
MIRT2294336	hsa-miR-4525	CLIP-seq
MIRT2294337	hsa-miR-4665-5p	CLIP-seq
MIRT2294338	hsa-miR-4723-5p	CLIP-seq
MIRT2456301	hsa-miR-4781-3p	CLIP-seq
MIRT2294343	hsa-miR-625	CLIP-seq
MIRT2456302	hsa-miR-633	CLIP-seq
MIRT2294324	hsa-miR-1275	CLIP-seq
MIRT2294327	hsa-miR-2110	CLIP-seq
MIRT2294328	hsa-miR-3147	CLIP-seq
MIRT2294329	hsa-miR-3150a-3p	CLIP-seq
MIRT2592261	hsa-miR-4267	CLIP-seq
MIRT2294333	hsa-miR-4425	CLIP-seq
MIRT2294334	hsa-miR-4450	CLIP-seq
MIRT2294336	hsa-miR-4525	CLIP-seq
MIRT2294337	hsa-miR-4665-5p	CLIP-seq
MIRT2592262	hsa-miR-4680-3p	CLIP-seq
MIRT2294338	hsa-miR-4723-5p	CLIP-seq
MIRT2456301	hsa-miR-4781-3p	CLIP-seq
MIRT2592263	hsa-miR-488	CLIP-seq
MIRT2294343	hsa-miR-625	CLIP-seq
MIRT2294324	hsa-miR-1275	CLIP-seq
MIRT2294327	hsa-miR-2110	CLIP-seq
MIRT2294328	hsa-miR-3147	CLIP-seq
MIRT2294329	hsa-miR-3150a-3p	CLIP-seq
MIRT2294333	hsa-miR-4425	CLIP-seq
MIRT2294334	hsa-miR-4450	CLIP-seq
MIRT2294336	hsa-miR-4525	CLIP-seq
MIRT2294337	hsa-miR-4665-5p	CLIP-seq
MIRT2294338	hsa-miR-4723-5p	CLIP-seq
MIRT2456301	hsa-miR-4781-3p	CLIP-seq
MIRT2294343	hsa-miR-625	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000287	Function	Magnesium ion binding	IEA
GO:0001725	Component	Stress fiber	IDA	8175905
GO:0004614	Function	Phosphoglucomutase activity	IBA
GO:0004614	Function	Phosphoglucomutase activity	IDA	8175905
GO:0005198	Function	Structural molecule activity	NAS	8631316
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005912	Component	Adherens junction	IBA
GO:0005912	Component	Adherens junction	IDA	8175905
GO:0005912	Component	Adherens junction	IEA
GO:0005914	Component	Spot adherens junction	IDA	8175905
GO:0005925	Component	Focal adhesion	IDA	8175905
GO:0005975	Process	Carbohydrate metabolic process	IBA
GO:0005975	Process	Carbohydrate metabolic process	IEA
GO:0007155	Process	Cell adhesion	IEA
GO:0009898	Component	Cytoplasmic side of plasma membrane	IDA	10867799
GO:0014704	Component	Intercalated disc	IDA	8175905
GO:0014706	Process	Striated muscle tissue development	IBA
GO:0016010	Component	Dystrophin-associated glycoprotein complex	IEA
GO:0016010	Component	Dystrophin-associated glycoprotein complex	ISS
GO:0016020	Component	Membrane	IEA
GO:0016868	Function	Intramolecular phosphotransferase activity	IEA
GO:0030018	Component	Z disc	IEA
GO:0030055	Component	Cell-substrate junction	IBA
GO:0030055	Component	Cell-substrate junction	IEA
GO:0030239	Process	Myofibril assembly	IBA
GO:0042383	Component	Sarcolemma	IBA
GO:0042383	Component	Sarcolemma	IDA	10867799
GO:0042383	Component	Sarcolemma	IEA
GO:0043034	Component	Costamere	IDA	8175905
GO:0070161	Component	Anchoring junction	IEA

MIM	HGNC	e!Ensembl
600981	8908	ENSG00000154330

Q15124

Protein name

Phosphoglucomutase-like protein 5 (Aciculin) (Phosphoglucomutase-related protein) (PGM-RP)

Protein function

Component of adherens-type cell-cell and cell-matrix junctions (PubMed:8175905). Has no phosphoglucomutase activity in vitro (PubMed:8175905).

PDB

7U21

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02878	PGM_PMM_I	19 → 163	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I	Domain
PF02879	PGM_PMM_II	198 → 306	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II	Domain
PF02880	PGM_PMM_III	311 → 425	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected in smooth and cardiac muscle at high levels and in skeletal muscle at low level. Present in other tissues due to vascular or other smooth muscle component. Low levels are present in liver, kidney, skin and brain (at protein le

Sequence

MEGSPIPVLTVPTAPYEDQRPAGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGC
TMVVGSDGRYFSRTAIEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIRKIKAAGGIILT
ASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYAICPDLRIDLSRLGRQEF
DLENKFKPFRVEIVDPVDIYLNLLRTIFDFHAIKGLLTGPSQLKIRIDAMHGVMGPYVRK
VLCDELGAPANSAINCVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYM
ILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSMALDRVAKSMKVPVYET
PAGWRFFSNLMDSGRCNLCGEESFGTGSDHLREKDGLWAVLVWLSIIAARKQSVEEIVRD
HWAKFGRHYYCRFDYEGLDPKTTYYIMRDLEALVTDKSFIGQQFAVGSHVYSVAKTDSFE
YVDPVDGTVTKKQGLRIIFSDASRLIFRLSSSSGVRATLRLYAESYERDPSGHDQEPQAV
LSPLIAIALKISQIHERTGRRGPTVIT

Sequence length

567

Interactions

View interactions

PGM5 (phosphoglucomutase 5)