PGAM1 (phosphoglycerate mutase 1)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5223 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Phosphoglycerate mutase 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PGAM1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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HEL-S-35, PGAM-B, PGAMA |
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Chromosome
Chromosome number
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10 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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10q24.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a mutase that catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Two transcript variants encoding different isoforms have been found for this gene. [ |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | P18669 | |||||||||||||||
| Protein name | Phosphoglycerate mutase 1 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B) | |||||||||||||||
| Protein function | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglyceratea crucial step in glycolysis, by using 2,3-bisphosphoglycerate (PubMed:23653202). Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-gly | |||||||||||||||
| PDB | 1YFK , 1YJX , 4GPI , 4GPZ , 5Y2I , 5Y2U , 5Y35 , 5Y64 , 5Y65 , 5ZRM , 5ZS8 , 6ISN , 7XB7 , 7XB8 , 7XB9 , 8IT4 , 8IT5 , 8IT6 , 8IT7 , 8IT8 , 8ITB , 8ITC , 8ITD | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in the liver and brain. Not found in the muscle. {ECO:0000269|PubMed:2846553}. | |||||||||||||||
| Sequence |
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| Sequence length | 254 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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