PFKP (phosphofructokinase, platelet)

Gene

• Entrez ID: 5214
• Gene name: Phosphofructokinase, platelet
• Gene symbol: PFKP
• Synonyms (NCBI Gene): ATP-PFK, PFK-C, PFK-P, PFKF
• Chromosome: 10
• Chromosome location: 10p15.2
• Summary: This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT007336	hsa-miR-520a-3p	Luciferase reporter assay	23389994
MIRT007337	hsa-miR-520b	Luciferase reporter assay	23389994
MIRT007338	hsa-miR-520e	Luciferase reporter assay	23389994
MIRT007336	hsa-miR-520a-3p	qRT-PCR, Western blot	23389994
MIRT007337	hsa-miR-520b	qRT-PCR, Western blot	23389994
MIRT007338	hsa-miR-520e	qRT-PCR, Western blot	23389994
MIRT030323	hsa-miR-26b-5p	Microarray	19088304
MIRT041540	hsa-miR-193b-3p	CLASH	23622248
MIRT039986	hsa-miR-615-3p	CLASH	23622248
MIRT037818	hsa-miR-455-3p	CLASH	23622248
MIRT056498	hsa-miR-302e	HITS-CLIP	21572407
MIRT056484	hsa-miR-302d-3p	HITS-CLIP	21572407
MIRT056485	hsa-miR-372-3p	HITS-CLIP	21572407
MIRT056486	hsa-miR-373-3p	HITS-CLIP	21572407
MIRT056483	hsa-miR-302c-3p	HITS-CLIP	21572407
MIRT056482	hsa-miR-302b-3p	HITS-CLIP	21572407
MIRT056481	hsa-miR-302a-3p	HITS-CLIP	21572407
MIRT007336	hsa-miR-520a-3p	HITS-CLIP	21572407
MIRT007338	hsa-miR-520e	HITS-CLIP	21572407
MIRT007337	hsa-miR-520b	HITS-CLIP	21572407
MIRT056492	hsa-miR-520c-3p	HITS-CLIP	21572407
MIRT056494	hsa-miR-520d-3p	HITS-CLIP	21572407
MIRT056478	hsa-miR-106a-5p	HITS-CLIP	21572407
MIRT056477	hsa-miR-93-5p	HITS-CLIP	21572407
MIRT056490	hsa-miR-526b-3p	HITS-CLIP	21572407
MIRT056476	hsa-miR-20a-5p	HITS-CLIP	21572407
MIRT056487	hsa-miR-20b-5p	HITS-CLIP	21572407
MIRT056493	hsa-miR-519d-3p	HITS-CLIP	21572407
MIRT056475	hsa-miR-17-5p	HITS-CLIP	21572407
MIRT056480	hsa-miR-106b-5p	HITS-CLIP	21572407
MIRT056501	hsa-miR-5590-3p	HITS-CLIP	21572407
MIRT056479	hsa-miR-142-5p	HITS-CLIP	21572407
MIRT506230	hsa-miR-3609	HITS-CLIP	21572407
MIRT506229	hsa-miR-548ah-5p	HITS-CLIP	21572407
MIRT506228	hsa-miR-4796-3p	HITS-CLIP	21572407
MIRT056496	hsa-miR-595	HITS-CLIP	21572407
MIRT056502	hsa-miR-6082	HITS-CLIP	21572407
MIRT056488	hsa-miR-512-3p	HITS-CLIP	21572407
MIRT056499	hsa-miR-3163	HITS-CLIP	21572407
MIRT056500	hsa-miR-4536-3p	HITS-CLIP	21572407
MIRT506227	hsa-miR-8075	HITS-CLIP	21572407
MIRT535362	hsa-miR-520d-5p	HITS-CLIP	21572407
MIRT535361	hsa-miR-524-5p	HITS-CLIP	21572407
MIRT056498	hsa-miR-302e	PAR-CLIP	20371350
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT056485	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT056486	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT007338	hsa-miR-520e	PAR-CLIP	20371350
MIRT007337	hsa-miR-520b	PAR-CLIP	20371350
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT056477	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT056475	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	20371350
MIRT056479	hsa-miR-142-5p	PAR-CLIP	20371350
MIRT506230	hsa-miR-3609	PAR-CLIP	20371350
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT056488	hsa-miR-512-3p	PAR-CLIP	20371350
MIRT056499	hsa-miR-3163	PAR-CLIP	20371350
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	20371350
MIRT506227	hsa-miR-8075	PAR-CLIP	20371350
MIRT056498	hsa-miR-302e	PAR-CLIP	20371350
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT056485	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT056486	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT007338	hsa-miR-520e	PAR-CLIP	20371350
MIRT007337	hsa-miR-520b	PAR-CLIP	20371350
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT056477	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT056475	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	20371350
MIRT056479	hsa-miR-142-5p	PAR-CLIP	20371350
MIRT506230	hsa-miR-3609	PAR-CLIP	20371350
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT056488	hsa-miR-512-3p	PAR-CLIP	20371350
MIRT056499	hsa-miR-3163	PAR-CLIP	20371350
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	20371350
MIRT506227	hsa-miR-8075	PAR-CLIP	20371350
MIRT056498	hsa-miR-302e	PAR-CLIP	21572407
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT056485	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT056486	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT007338	hsa-miR-520e	PAR-CLIP	21572407
MIRT007337	hsa-miR-520b	PAR-CLIP	21572407
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT056477	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT056475	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	21572407
MIRT056479	hsa-miR-142-5p	PAR-CLIP	21572407
MIRT506230	hsa-miR-3609	PAR-CLIP	21572407
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT056488	hsa-miR-512-3p	PAR-CLIP	21572407
MIRT056499	hsa-miR-3163	PAR-CLIP	21572407
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	21572407
MIRT506227	hsa-miR-8075	PAR-CLIP	21572407
MIRT056498	hsa-miR-302e	PAR-CLIP	22012620
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	22012620
MIRT056485	hsa-miR-372-3p	PAR-CLIP	22012620
MIRT056486	hsa-miR-373-3p	PAR-CLIP	22012620
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	22012620
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	22012620
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	22012620
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	22012620
MIRT007338	hsa-miR-520e	PAR-CLIP	22012620
MIRT007337	hsa-miR-520b	PAR-CLIP	22012620
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	22012620
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	22012620
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT056477	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT056475	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	22012620
MIRT056479	hsa-miR-142-5p	PAR-CLIP	22012620
MIRT506230	hsa-miR-3609	PAR-CLIP	22012620
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	22012620
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	22012620
MIRT056496	hsa-miR-595	PAR-CLIP	22012620
MIRT056488	hsa-miR-512-3p	PAR-CLIP	22012620
MIRT056499	hsa-miR-3163	PAR-CLIP	22012620
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	22012620
MIRT506227	hsa-miR-8075	PAR-CLIP	22012620
MIRT535362	hsa-miR-520d-5p	PAR-CLIP	22012620
MIRT535361	hsa-miR-524-5p	PAR-CLIP	22012620
MIRT056498	hsa-miR-302e	PAR-CLIP	23446348
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT056485	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT056486	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT007338	hsa-miR-520e	PAR-CLIP	23446348
MIRT007337	hsa-miR-520b	PAR-CLIP	23446348
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT056477	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT056475	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	23446348
MIRT056479	hsa-miR-142-5p	PAR-CLIP	23446348
MIRT506230	hsa-miR-3609	PAR-CLIP	23446348
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	23446348
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	23446348
MIRT056488	hsa-miR-512-3p	PAR-CLIP	23446348
MIRT056499	hsa-miR-3163	PAR-CLIP	23446348
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	23446348
MIRT506227	hsa-miR-8075	PAR-CLIP	23446348
MIRT056498	hsa-miR-302e	PAR-CLIP	23446348
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT056485	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT056486	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT007338	hsa-miR-520e	PAR-CLIP	23446348
MIRT007337	hsa-miR-520b	PAR-CLIP	23446348
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT056477	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT056475	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	23446348
MIRT056479	hsa-miR-142-5p	PAR-CLIP	23446348
MIRT506230	hsa-miR-3609	PAR-CLIP	23446348
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	23446348
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	23446348
MIRT056488	hsa-miR-512-3p	PAR-CLIP	23446348
MIRT056499	hsa-miR-3163	PAR-CLIP	23446348
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	23446348
MIRT506227	hsa-miR-8075	PAR-CLIP	23446348
MIRT056480	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT056476	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT056480	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT056475	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT056487	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT056477	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT056493	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT056476	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT056498	hsa-miR-302e	HITS-CLIP	21572407
MIRT056484	hsa-miR-302d-3p	HITS-CLIP	21572407
MIRT056485	hsa-miR-372-3p	HITS-CLIP	21572407
MIRT056486	hsa-miR-373-3p	HITS-CLIP	21572407
MIRT056483	hsa-miR-302c-3p	HITS-CLIP	21572407
MIRT056482	hsa-miR-302b-3p	HITS-CLIP	21572407
MIRT056481	hsa-miR-302a-3p	HITS-CLIP	21572407
MIRT007336	hsa-miR-520a-3p	HITS-CLIP	21572407
MIRT007338	hsa-miR-520e	HITS-CLIP	21572407
MIRT007337	hsa-miR-520b	HITS-CLIP	21572407
MIRT056492	hsa-miR-520c-3p	HITS-CLIP	21572407
MIRT056494	hsa-miR-520d-3p	HITS-CLIP	21572407
MIRT056478	hsa-miR-106a-5p	HITS-CLIP	21572407
MIRT056477	hsa-miR-93-5p	HITS-CLIP	21572407
MIRT056490	hsa-miR-526b-3p	HITS-CLIP	21572407
MIRT056476	hsa-miR-20a-5p	HITS-CLIP	21572407
MIRT056487	hsa-miR-20b-5p	HITS-CLIP	21572407
MIRT056493	hsa-miR-519d-3p	HITS-CLIP	21572407
MIRT056475	hsa-miR-17-5p	HITS-CLIP	21572407
MIRT056480	hsa-miR-106b-5p	HITS-CLIP	21572407
MIRT056501	hsa-miR-5590-3p	HITS-CLIP	21572407
MIRT056479	hsa-miR-142-5p	HITS-CLIP	21572407
MIRT506230	hsa-miR-3609	HITS-CLIP	21572407
MIRT506229	hsa-miR-548ah-5p	HITS-CLIP	21572407
MIRT506228	hsa-miR-4796-3p	HITS-CLIP	21572407
MIRT056496	hsa-miR-595	HITS-CLIP	21572407
MIRT056502	hsa-miR-6082	HITS-CLIP	21572407
MIRT056488	hsa-miR-512-3p	HITS-CLIP	21572407
MIRT056499	hsa-miR-3163	HITS-CLIP	21572407
MIRT056500	hsa-miR-4536-3p	HITS-CLIP	21572407
MIRT506227	hsa-miR-8075	HITS-CLIP	21572407
MIRT535362	hsa-miR-520d-5p	HITS-CLIP	21572407
MIRT535361	hsa-miR-524-5p	HITS-CLIP	21572407
MIRT056498	hsa-miR-302e	PAR-CLIP	20371350
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT056485	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT056486	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT007338	hsa-miR-520e	PAR-CLIP	20371350
MIRT007337	hsa-miR-520b	PAR-CLIP	20371350
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT056477	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT056475	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	20371350
MIRT056479	hsa-miR-142-5p	PAR-CLIP	20371350
MIRT506230	hsa-miR-3609	PAR-CLIP	20371350
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT056488	hsa-miR-512-3p	PAR-CLIP	20371350
MIRT056499	hsa-miR-3163	PAR-CLIP	20371350
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	20371350
MIRT506227	hsa-miR-8075	PAR-CLIP	20371350
MIRT056498	hsa-miR-302e	PAR-CLIP	20371350
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT056485	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT056486	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT007338	hsa-miR-520e	PAR-CLIP	20371350
MIRT007337	hsa-miR-520b	PAR-CLIP	20371350
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT056477	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT056475	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	20371350
MIRT056479	hsa-miR-142-5p	PAR-CLIP	20371350
MIRT506230	hsa-miR-3609	PAR-CLIP	20371350
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT056488	hsa-miR-512-3p	PAR-CLIP	20371350
MIRT056499	hsa-miR-3163	PAR-CLIP	20371350
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	20371350
MIRT506227	hsa-miR-8075	PAR-CLIP	20371350
MIRT056498	hsa-miR-302e	PAR-CLIP	21572407
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT056485	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT056486	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT007338	hsa-miR-520e	PAR-CLIP	21572407
MIRT007337	hsa-miR-520b	PAR-CLIP	21572407
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT056477	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT056475	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	21572407
MIRT056479	hsa-miR-142-5p	PAR-CLIP	21572407
MIRT506230	hsa-miR-3609	PAR-CLIP	21572407
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT056488	hsa-miR-512-3p	PAR-CLIP	21572407
MIRT056499	hsa-miR-3163	PAR-CLIP	21572407
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	21572407
MIRT506227	hsa-miR-8075	PAR-CLIP	21572407
MIRT056498	hsa-miR-302e	PAR-CLIP	22012620
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	22012620
MIRT056485	hsa-miR-372-3p	PAR-CLIP	22012620
MIRT056486	hsa-miR-373-3p	PAR-CLIP	22012620
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	22012620
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	22012620
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	22012620
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	22012620
MIRT007338	hsa-miR-520e	PAR-CLIP	22012620
MIRT007337	hsa-miR-520b	PAR-CLIP	22012620
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	22012620
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	22012620
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT056477	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT056475	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	22012620
MIRT056479	hsa-miR-142-5p	PAR-CLIP	22012620
MIRT506230	hsa-miR-3609	PAR-CLIP	22012620
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	22012620
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	22012620
MIRT056496	hsa-miR-595	PAR-CLIP	22012620
MIRT056488	hsa-miR-512-3p	PAR-CLIP	22012620
MIRT056499	hsa-miR-3163	PAR-CLIP	22012620
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	22012620
MIRT506227	hsa-miR-8075	PAR-CLIP	22012620
MIRT535362	hsa-miR-520d-5p	PAR-CLIP	22012620
MIRT535361	hsa-miR-524-5p	PAR-CLIP	22012620
MIRT056498	hsa-miR-302e	PAR-CLIP	23446348
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT056485	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT056486	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT007338	hsa-miR-520e	PAR-CLIP	23446348
MIRT007337	hsa-miR-520b	PAR-CLIP	23446348
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT056477	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT056475	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	23446348
MIRT056479	hsa-miR-142-5p	PAR-CLIP	23446348
MIRT506230	hsa-miR-3609	PAR-CLIP	23446348
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	23446348
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	23446348
MIRT056488	hsa-miR-512-3p	PAR-CLIP	23446348
MIRT056499	hsa-miR-3163	PAR-CLIP	23446348
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	23446348
MIRT506227	hsa-miR-8075	PAR-CLIP	23446348
MIRT056498	hsa-miR-302e	PAR-CLIP	23446348
MIRT056484	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT056485	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT056486	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT056483	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT056482	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT056481	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT007336	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT007338	hsa-miR-520e	PAR-CLIP	23446348
MIRT007337	hsa-miR-520b	PAR-CLIP	23446348
MIRT056492	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT056494	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT056478	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT056477	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT056490	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT056476	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT056487	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT056493	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT056475	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT056480	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT056501	hsa-miR-5590-3p	PAR-CLIP	23446348
MIRT056479	hsa-miR-142-5p	PAR-CLIP	23446348
MIRT506230	hsa-miR-3609	PAR-CLIP	23446348
MIRT506229	hsa-miR-548ah-5p	PAR-CLIP	23446348
MIRT506228	hsa-miR-4796-3p	PAR-CLIP	23446348
MIRT056488	hsa-miR-512-3p	PAR-CLIP	23446348
MIRT056499	hsa-miR-3163	PAR-CLIP	23446348
MIRT056500	hsa-miR-4536-3p	PAR-CLIP	23446348
MIRT506227	hsa-miR-8075	PAR-CLIP	23446348
MIRT1226464	hsa-miR-106a	CLIP-seq
MIRT1226465	hsa-miR-106b	CLIP-seq
MIRT1226466	hsa-miR-1324	CLIP-seq
MIRT1226467	hsa-miR-17	CLIP-seq
MIRT1226468	hsa-miR-20a	CLIP-seq
MIRT1226469	hsa-miR-20b	CLIP-seq
MIRT1226470	hsa-miR-302a	CLIP-seq
MIRT1226471	hsa-miR-302b	CLIP-seq
MIRT1226472	hsa-miR-302c	CLIP-seq
MIRT1226473	hsa-miR-302d	CLIP-seq
MIRT1226474	hsa-miR-3151	CLIP-seq
MIRT1226475	hsa-miR-331-5p	CLIP-seq
MIRT1226476	hsa-miR-3665	CLIP-seq
MIRT1226477	hsa-miR-369-3p	CLIP-seq
MIRT1226478	hsa-miR-372	CLIP-seq
MIRT1226479	hsa-miR-373	CLIP-seq
MIRT1226480	hsa-miR-4678	CLIP-seq
MIRT1226481	hsa-miR-486-3p	CLIP-seq
MIRT1226482	hsa-miR-517b	CLIP-seq
MIRT1226483	hsa-miR-519d	CLIP-seq
MIRT1226484	hsa-miR-521	CLIP-seq
MIRT1226485	hsa-miR-548ah	CLIP-seq
MIRT1226486	hsa-miR-93	CLIP-seq
MIRT1226464	hsa-miR-106a	CLIP-seq
MIRT1226465	hsa-miR-106b	CLIP-seq
MIRT1226467	hsa-miR-17	CLIP-seq
MIRT1226468	hsa-miR-20a	CLIP-seq
MIRT1226469	hsa-miR-20b	CLIP-seq
MIRT1226470	hsa-miR-302a	CLIP-seq
MIRT1226471	hsa-miR-302b	CLIP-seq
MIRT1226472	hsa-miR-302c	CLIP-seq
MIRT1226473	hsa-miR-302d	CLIP-seq
MIRT1226475	hsa-miR-331-5p	CLIP-seq
MIRT1226477	hsa-miR-369-3p	CLIP-seq
MIRT1226478	hsa-miR-372	CLIP-seq
MIRT1226479	hsa-miR-373	CLIP-seq
MIRT1226480	hsa-miR-4678	CLIP-seq
MIRT1226482	hsa-miR-517b	CLIP-seq
MIRT1226483	hsa-miR-519d	CLIP-seq
MIRT1226485	hsa-miR-548ah	CLIP-seq
MIRT1226486	hsa-miR-93	CLIP-seq
MIRT1226475	hsa-miR-331-5p	CLIP-seq
MIRT1226480	hsa-miR-4678	CLIP-seq
MIRT1226466	hsa-miR-1324	CLIP-seq
MIRT1226484	hsa-miR-521	CLIP-seq
MIRT2066354	hsa-miR-603	CLIP-seq
MIRT1226474	hsa-miR-3151	CLIP-seq
MIRT1226475	hsa-miR-331-5p	CLIP-seq
MIRT1226476	hsa-miR-3665	CLIP-seq
MIRT1226480	hsa-miR-4678	CLIP-seq
MIRT1226481	hsa-miR-486-3p	CLIP-seq
MIRT1226464	hsa-miR-106a	CLIP-seq
MIRT1226465	hsa-miR-106b	CLIP-seq
MIRT1226467	hsa-miR-17	CLIP-seq
MIRT1226468	hsa-miR-20a	CLIP-seq
MIRT1226469	hsa-miR-20b	CLIP-seq
MIRT1226470	hsa-miR-302a	CLIP-seq
MIRT1226471	hsa-miR-302b	CLIP-seq
MIRT1226472	hsa-miR-302c	CLIP-seq
MIRT1226473	hsa-miR-302d	CLIP-seq
MIRT1226478	hsa-miR-372	CLIP-seq
MIRT1226479	hsa-miR-373	CLIP-seq
MIRT1226482	hsa-miR-517b	CLIP-seq
MIRT1226483	hsa-miR-519d	CLIP-seq
MIRT1226485	hsa-miR-548ah	CLIP-seq
MIRT1226486	hsa-miR-93	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
KLF4	Activation	21586797
ZBTB7A	Repression	25184678

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003824	Function	Catalytic activity	IEA
GO:0003872	Function	6-phosphofructokinase activity	IBA
GO:0003872	Function	6-phosphofructokinase activity	IEA
GO:0003872	Function	6-phosphofructokinase activity	ISS
GO:0003872	Function	6-phosphofructokinase activity	TAS	1834056
GO:0005515	Function	Protein binding	IPI	28514442, 32296183, 33961781
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005737	Component	Cytoplasm	IDA	25468996
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005945	Component	6-phosphofructokinase complex	IBA
GO:0006002	Process	Fructose 6-phosphate metabolic process	IBA
GO:0006002	Process	Fructose 6-phosphate metabolic process	IEA
GO:0006096	Process	Glycolytic process	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IBA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030388	Process	Fructose 1,6-bisphosphate metabolic process	IBA
GO:0042802	Function	Identical protein binding	IPI	25985179
GO:0044877	Function	Protein-containing complex binding	IDA	23209302
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0046872	Function	Metal ion binding	IEA
GO:0061621	Process	Canonical glycolysis	IBA
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:0070095	Function	Fructose-6-phosphate binding	IBA
GO:1990830	Process	Cellular response to leukemia inhibitory factor	IEA

Other IDs

• MIM: 171840
• HGNC: 8878
• e!Ensembl: ENSG00000067057

Protein

• UniProt ID: Q01813
• Protein name: ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)
• Protein function: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
• PDB: 4RH3, 4U1R, 4WL0, 4XYJ, 4XYK, 4XZ2, 7TFF
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00365	PFK	26 → 333	Phosphofructokinase	Domain
  PF00365	PFK	412 → 697	Phosphofructokinase	Domain

• Sequence:

  MDADDSRAPKGSLRKFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFI
  YEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGIT
  NLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCG
  TDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLP
  ESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDT
  RVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMEC
  VQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGA
  PAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTK
  RVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVS
  NNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGA
  DAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKG
  VFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARGRGKKFTTDDSICVL
  GISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQ
  PWSV

• Sequence length: 784

Pathways

KEGG:

Glycolysis / Gluconeogenesis
Pentose phosphate pathway
Fructose and mannose metabolism
Galactose metabolism
Metabolic pathways
Carbon metabolism
Biosynthesis of amino acids
RNA degradation
HIF-1 signaling pathway
AMPK signaling pathway
Thyroid hormone signaling pathway
Glucagon signaling pathway
Central carbon metabolism in cancer

Reactome:

Glycolysis

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Anophthalmia-microphthalmia syndrome	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONNECTIVE TISSUE DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MIXED CONNECTIVE TISSUE DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PFKP-related disorder	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Adenocarcinoma	Associate	27767175	★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of Lung	Associate	33839701	★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Associate	34857756	★☆☆☆☆ Found in Text Mining only
Anophthalmia with pulmonary hypoplasia	Associate	32633891	★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Associate	37845777	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	21586797, 32927665, 37833332	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Associate	30168613, 36362375, 36753968	★☆☆☆☆ Found in Text Mining only
Carcinoma Non Small Cell Lung	Stimulate	33236133	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Associate	34596153, 36901940	★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Associate	34857756	★☆☆☆☆ Found in Text Mining only
Death	Associate	37326348	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Stimulate	37420311	★☆☆☆☆ Found in Text Mining only
Graft vs Host Disease	Associate	35401560	★☆☆☆☆ Found in Text Mining only
Heterotaxy Syndrome	Associate	27821535	★☆☆☆☆ Found in Text Mining only
Histiocytoma Angiomatoid Fibrous	Associate	35347249	★☆☆☆☆ Found in Text Mining only
Hypoxia	Associate	34596153, 36362375	★☆☆☆☆ Found in Text Mining only
Keratoderma Palmoplantar	Associate	30168613	★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Associate	38305210	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Associate	37833332	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Associate	33236133	★☆☆☆☆ Found in Text Mining only
Mouth Neoplasms	Associate	31638999	★☆☆☆☆ Found in Text Mining only
Muscular Diseases	Associate	39438952	★☆☆☆☆ Found in Text Mining only
Neoplasm Metastasis	Associate	34396983, 35067686	★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	33236133, 35067686, 36901940, 37622331, 37833332, 38217030	★☆☆☆☆ Found in Text Mining only
Obesity	Associate	18325910, 18682847, 20712903	★☆☆☆☆ Found in Text Mining only
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	34396983	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Associate	30866497, 36536346	★☆☆☆☆ Found in Text Mining only
Sarcoma Clear Cell	Associate	35347249	★☆☆☆☆ Found in Text Mining only
Sepsis	Associate	39438952	★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Associate	34440660, 38217030	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Associate	37326348	★☆☆☆☆ Found in Text Mining only