Gene Gene information from NCBI Gene database.
Entrez ID 51808
Gene name Phosphorylated adaptor for RNA export
Gene symbol PHAX
Synonyms (NCBI Gene)
RNUXA
Chromosome 5
Chromosome location 5q23.2
miRNA miRNA information provided by mirtarbase database.
923
miRTarBase ID miRNA Experiments Reference
MIRT046788 hsa-miR-222-3p CLASH 23622248
MIRT044226 hsa-miR-301a-3p CLASH 23622248
MIRT039057 hsa-miR-769-3p CLASH 23622248
MIRT566454 hsa-miR-548c-3p HITS-CLIP 23313552
MIRT695374 hsa-miR-6732-3p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding IEA
GO:0005515 Function Protein binding IPI 26382858
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604924 10241 ENSG00000164902
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9H814
Protein name Phosphorylated adapter RNA export protein (RNA U small nuclear RNA export adapter protein)
Protein function A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus (PubMed:39011894). Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active G
PDB 2XC7 , 8PNT
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF10258 RNA_GG_bind 230 313 PHAX RNA-binding domain Domain
Sequence
MALEVGDMEDGQLSDSDSDMTVAPSDRPLQLPKVLGGDSAMRAFQNTATACAPVSHYRAV
ESVDSSEESFSDSDDDSCLWKRKRQKCFNPPPKPEPFQFGQSSQKPPVAGGKKINNIWGA
VLQEQNQDAVATELGILGMEGTIDRSRQSETYNYLLAKKLRKESQEHTKDLDKELDEYMH
GGKKMGSKEEENGQGHLKRKRPVKDRLGNRPEMNYKGRYEITAEDSQEKVADEISFRLQE
PKKDLIARVVRIIGNKKAIELLMETAEVEQNGGLFIMNGSRRRTPGGVFLNLLKNTPSIS
EEQIKDIFYIENQ
KEYENKKAARKRRTQVLGKKMKQAIKSLNFQEDDDTSRETFASDTNE
ALASLDESQEGHAEAKLEAEEAIEVDHSHDLDIF
Sequence length 394
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Nucleocytoplasmic transport   snRNP Assembly
RNA polymerase II transcribes snRNA genes
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Aganglionic megacolon Uncertain significance rs1581415304 RCV000984782